Incorporación de nuevas metodologías docentes en las asignaturas de Acondicionamiento y Servicios del Grado en Fundamentos de la Arquitectura

Tras los resultados obtenidos a lo largo del curso académico 14/15 con motivo de la red sobre trabajo colaborativo realizada el curso anterior entre las asignaturas de Acondicionamiento y Servicios 1 y 2 del Grado en Fundamentos de Arquitectura de 3º y 4º curso respectivamente, se propone esta nueva red como continuación de la anterior, con el propósito fundamental de la implementación de la nueva metodología de aprendizaje colaborativo entre ambas asignaturas. A lo largo de estas asignaturas los alumnos deben adquirir la capacidad de trabajo en grupo, repartiendo las tareas y asumiendo roles. A través de un supuesto práctico real común para las dos asignaturas, deben proyectar y resolver problemas reales demandados por la sociedad en el ámbito de la arquitectura, en concreto en el campo de las instalaciones de edificación. La participación conjunta de este taller vertical entre alumnos de 3º y 4º de arquitectura, en la resolución de los trabajos propuestos, habilita a los alumnos para la integración de los distintos saberes y disciplinas, así como aporta la motivación para el trabajo en equipo con responsabilidades compartidas

Red de desarrollo de metodología de trabajo colaborativo entre las asignaturas de Acondicionamiento y Servicios I y II del Grado en Arquitectura

El propósito fundamental de esta red es la implantación de una nueva metodología de aprendizaje colaborativo entre las asignaturas de Acondicionamiento y Servicios I de 3º y Acondicionamiento y Servicios II de 4º del Grado en Fundamentos de Arquitectura. A lo largo de estas asignaturas los alumnos deben adquirir la capacidad de trabajo en grupo, repartiendo las tareas y asumiendo roles. A través de un supuesto práctico real común para las dos asignaturas, deben proyectar y resolver problemas reales demandados por la sociedad en el ámbito de la arquitectura, en concreto en el campo de las instalaciones de edificación. La participación conjunta de este taller vertical entre alumnos de 3º y 4º de arquitectura, en la resolución de los trabajos propuestos, habilita a los alumnos para la integración de los distintos saberes y disciplinas, así como aporta la motivación para el trabajo en equipo con responsabilidades compartidas

Integración de las asignaturas de Construcción y Acondicionamiento y servicios en Arquitectura. Hacia una materialización del proyecto arquitectónico

El proyecto Arquitectónico es una realidad compleja, en la que han de integrarse un gran abanico de conocimientos de diversas disciplinas, a la vez que en el proceso creativo hay que garantizar su viabilidad, ejecución posible de las obras, mantenimiento de la edificación una vez en uso, cumplimiento de las normativas vigentes, etc. También son críticos aspectos como la eficiencia energética de los edificios, su respeto hacia el medio ambiente, el confort del ambiente interior de las estancias y espacios arquitectónicos, etc. Es fácil pues entender la complejidad de dicha actividad, complejidad que también se manifiesta a la hora de formar a los futuros arquitectos, que serán los verdaderos proyectistas directores de ejecución de dichas obras de Arquitectura. En dicho proceso formativo de los futuros técnicos en las Escuelas de Arquitectura, la coordinación entre las diversas materias de Construcción y Acondicionamiento y Servicios es fundamental. En esta comunicación se exponen algunas iniciativas de coordinación llevadas a cabo en el curso académico 2014/15 en los estudios de Grado en Arquitectura y Grado en Fundamentos de la Arquitectura. Se ha plasmado a través de las actividades de dos Cátedras de Empresa: la Cátedra Marjal de la Universidad de Alicante, y el Taller Cerámico dentro del Convenio ASCER-UA. Ambas Cátedras están dirigidas por profesores del Departamento de Construcciones Arquitectónicas, lo que ha facilitado dicha coordinación. Cada una de ellas se enmarca en cada una de las dos Areas: Construcción y Acondicionamiento y Servicios

COVID-19: Some unresolved issues

Two years after the COVID-19 pandemic, many uncertainties persist about the causal agent, the disease and its future. This document contains the reflection of the COVID-19 working group of the Official College of Physicians of Madrid (ICOMEM) in relation to some questions that remain unresolved. The document includes considerations on the origin of the virus, the current indication for diagnostic tests, the value of severity scores in the onset of the disease and the added risk posed by hypertension or dementia. We also discuss the possibility of deducing viral behavior from the examination of the structure of the complete viral genome, the future of some drug associations and the current role of therapeutic resources such as corticosteroids or extracorporeal oxygenation (ECMO). We review the scarce existing information on the reality of COVID 19 in Africa, the uncertainties about the future of the pandemic and the status of vaccines, and the data and uncertainties about the long-term pulmonary sequelae of those who suffered severe pneumonia.post-print462 K

New variants of SARS-CoV-2

The emergence and spread of new variants of SARS-CoV-2 has produced enormous interest due to their possible implication in the improved transmissibility of the virus, their consequences in the individual evolution of the infection, as well as in the possible escape from the immunity generated by the current vaccines. The variants that attract most attention are those of public health concern, including B.1.1.7 (UK), P.1 (Brazilian) and B.1.351 (South African). This list is extended by the variants of interest that emerge and are expanding in certain countries but are found sporadically in others, such as B.1.427 and B.1.429 (Californians) or B.1.617 (Indian). Whole genome sequencing or strategies specifically targeting the spicule gene are used in the microbiology laboratories for characterization and detection. The number of infected individuals, the sanitary situation of each country, epidemiological measures and vaccination strategies influence its dispersion and new variants are expected to emerge. This emergence can only be avoided today by increasing the vaccinated population in all countries and by not relaxing epidemiological containment measures. It is not excluded that in the future it will be necessary to revaccinate against new variants.post-print186 K

Persistence and viability of SARS-CoV-2 in primary infection and reinfections

Since the beginning of the SARS-CoV-2 epidemic, virus isolation in the infected patient was only possible for a short period of time and it was striking that this occurred constantly and did not provide guidance on the clinical course. This fact led to confusion about the efficacy of some of the drugs initially used, which seemed to have a high efficiency in viral clearance and proved ineffective in modifying the course of the disease. The immune response also did not prove to be definitive in terms of evolution, although most of the patients with very mild disease had a weak or no antibody response, and the opposite was true for the most severe patients. With whatever the antibody response, few cases have been re-infected after a first infection and generally, those that have, have not reproduced a spectrum of disease similar to the first infection. Among those re-infected, a large number have been asymptomatic or with very few symptoms, others have had a moderate picture and very few have had a poor evolution. Despite this dynamic of rapid viral clearance, laboratory tests were still able to generate positive results in the recovery of genomic sequences and this occurred in patients who were already symptom-free, in others who were still ill and in those who were very seriously ill. There was also no good correlate. For this reason and with the perspective of this year and the half of pandemic, we compiled what the literature leaves us in these aspects and anticipating that, as always in biology, there are cases that jump the limits of the general behavior of the dynamics of infection in genera

Actions and attitudes on the immunized patients against SARS-CoV-2

The access to COVID vaccines by millions of human beings and their high level of protection against the disease, both in its mild and severe forms, together with a plausible decrease in the transmission of the infection from vaccinated patients, has prompted a series of questions from the members of the College of Physicians of Madrid (ICOMEM) and the society. The ICOMEM Scientific Committee on this subject has tried to answer these questions after discussion and consensus among its members. The main answers can be summarized as follows: The occurrence of new SARS-CoV-2 infections in both vaccinated and previously infected patients is very low, in the observation time we already have. When breakthrough infections do occur, they are usually asymptomatic or mild and, purportedly, should have a lower capacity for transmission to other persons. Vaccinated subjects who have contact with a SARS-CoV-2 infected patient can avoid quarantine as long as they are asymptomatic, although this decision depends on variables such as age, occupation, circulating variants, degree of contact and time since vaccination. In countries with a high proportion of the population vaccinated, it is already suggested that fully vaccinated persons could avoid the use of masks and social distancing in most circumstances. Systematic use of diagnostic tests to assess the immune response or the degree of protection against reinfection after natural infection or vaccination is discouraged, since their practical consequences are not known at this time. The existing information precludes any precision regarding a possible need for future revaccination. This Committee considers that when mass vaccination of health care workers and the general population is achieved, SARS-CoV-2 screening tests could be avoided at least in out-patient care and in the case of exploratory procedures that do not require hospitalizatio

Vacunación anti-COVID-19: la realidad tras los ensayos clínicos.

Tras el comienzo de la vacunación frente a SARS-CoV-2, se está acumulando ya suficiente experiencia clínica, en el mundo real y fuera de los ensayos clínicos, para resolver algunas de las cuestiones que siguen pendientes sobre este problema. El Comité Científico sobre COVID-19 del Colegio de Médicos de Madrid ha discutido y revisado algunos de estos temas con una aproximación multidisciplinar. El documento que sigue es un intento de responder a algunas de dichas cuestiones con la información disponible hasta el momento. Este documento se ha estructurado en preguntas sobre distintos aspectos de las indicaciones, eficacia y tolerancia de la vacunación anti- COVID-19.post-print214 K

CIBERER : Spanish national network for research on rare diseases: A highly productive collaborative initiative

Altres ajuts: Instituto de Salud Carlos III (ISCIII); Ministerio de Ciencia e Innovación.CIBER (Center for Biomedical Network Research; Centro de Investigación Biomédica En Red) is a public national consortium created in 2006 under the umbrella of the Spanish National Institute of Health Carlos III (ISCIII). This innovative research structure comprises 11 different specific areas dedicated to the main public health priorities in the National Health System. CIBERER, the thematic area of CIBER focused on rare diseases (RDs) currently consists of 75 research groups belonging to universities, research centers, and hospitals of the entire country. CIBERER's mission is to be a center prioritizing and favoring collaboration and cooperation between biomedical and clinical research groups, with special emphasis on the aspects of genetic, molecular, biochemical, and cellular research of RDs. This research is the basis for providing new tools for the diagnosis and therapy of low-prevalence diseases, in line with the International Rare Diseases Research Consortium (IRDiRC) objectives, thus favoring translational research between the scientific environment of the laboratory and the clinical setting of health centers. In this article, we intend to review CIBERER's 15-year journey and summarize the main results obtained in terms of internationalization, scientific production, contributions toward the discovery of new therapies and novel genes associated to diseases, cooperation with patients' associations and many other topics related to RD research