Experiencing Remote Classical Music Performance Over Long Distance: A JackTrip Concert Between Two Continents During the Pandemic

The recent lockdown restrictions imposed by the severe acute respiratory syndrome coronavirus 2 pandemic have heightened the need for new forms of remote collaboration for music schools, conservatories, musician ensembles, and artists, each of which would benefit from being provided with adequate tools to make high-quality, live collaborative music in a distributed fashion. This paper demonstrates the usage of the Networked Music Performance software JackTrip to support a distributed classical concert involving singers and musicians from four different locations in two continents, using readily available hardware/software solutions and internet connections while guaranteeing high-fidelity audio quality. This paper provides a description of the technical setup with a numerical analysis of the achieved mouth-to-ear latency and assessment of the music-making experience as perceived by the performers

Defective FoxP3+ Treg cell differentiation in the gut of Type 1 Diabetic patients

Environmental factors that act at the intestinal level such as diet, drugs, and microflora have a high impact on the pathogenesis of autoimmune Type 1 Diabetes (T1D), but it is still unclear how the gut milieu affects autoimmunity outside the intestine. Here we show that peripheral FoxP3+ Treg cell differentiation, a mechanism that takes place in the gut and is crucial to maintain systemic immune tolerance, is impaired in T1D patients. These results provide the first evidence that gut mucosa alteration could predispose to autoimmune T1D by affecting systemic immune regulation

Apoio social percebido por pacientes oncológicos e sua relação com as características sociodemográficas

To analyze the relation between social support and socio-demographic characteristics of oncology patients. Transversal study, developed with oncology patients living in the Ijuí city, Rio Grande do Sul state, Brazil between July and December 2012, the population was selected through convenience. For data collection we used the Brazilian version of the Social Support Scale and the Medical Outcomes Study data were analyzed with descriptive statistics resources and analytical. Average scores on the dimensions were: 82,36±24,42 (positive interaction), 85,39± 19,81(information), 87,98±18,68 (emotional support), 88,52±18,56 (material support) and 93,50±14,44 (affective support). Evidences showed higher averages in male mulattos patients (p<0,05). There was a direct and growing relationship between per capita income, social support and affective positive interaction. It was proven that patients receive social support in all dimensions, with high scores, but with variations, considering the characteristics of gender, civil status, educational level, per capita income and race.Analizar la relación entre el apoyo social y las características sociodemográficas de los pacientes oncológicos. Estudio transversal, cuantitativo realizado con 268 enfermos de cáncer que residen en la ciudad de Ijuí / Rio Grande do Sul, Brasil, entre julio y diciembre de 2012. Para la recolección de datos se utilizó la versión brasileña de la Escala de Apoyo Social y los datos del estudio los resultados médicos se analizaron con los recursos estadísticos descriptivos y analíticos. Las puntuaciones medias en las dimensiones fueron 82,36 ± 24,42 (interacción positiva), 85,39 ± 19,81 (información), 87,98 ± 18,68 (apoyo emocional), 88,52 ± 18,56 (apoyo material) y 93,50 ± 14,44 (apoyo afectivo). Puntuaciones medias más altas son encontradas entre los pacientes de sexo masculino y mulatos (p<0,05). Se observó relación directa y creciente entre el ingreso per capita, el apoyo social afectivo y la interacción positiva. Se comprobó que los pacientes reciben apoyo social en todas las dimensiones, con altas puntuaciones, pero con variaciones, teniendo en cuenta las características de género, estado civil, educación, ingreso per capita y raza.Analisar a relação entre o apoio social e características sociodemográficas de pacientes oncológicos. Estudo transversal, realizado com 268 pacientes oncológicos, residentes no Município de Ijuí, Rio Grande do Sul, Brasil, no período entre julho e dezembro de 2012. Para a coleta de dados, utilizou-se a versão brasileira da Escala de Apoio Social do Medical Outcomes Study e os dados foram analisados com os recursos da estatística descritiva e analítica. Os escores médios nas dimensões foram: 82,36±24,42 (interação positiva), 85,39± 19,81(informação), 87,98±18,68 (apoio emocional), 88,52±18,56 (apoio material) e 93,50±14,44 (apoio afetivo). Maiores médias foram obtidas entre os pacientes do sexo masculino e etnia parda (p<0,05). Houve relação direta e crescente, entre renda per capita, apoio social afetivo e interação positiva. Evidenciou-se que os pacientes recebem apoio social em todas as dimensões, com elevados escores, porém com variações, considerando as características sexo, estado civil, escolaridade, renda per capita e etnia.Universidade do Noroeste do Estado do Rio Grande do Sul Department of Life SciencesUNIJUÍFederal University of Santa Maria Department of NursingUNIFESP Paulista School of Nursing Department of Clinical and Surgical NursingUNIFESP, EPE Department of Clinical and Surgical NursingSciEL

The Burden of Structured Self-Monitoring of Blood Glucose on Diabetes-Specific Quality of Life and Locus of Control in Patients with Noninsulin-Treated Type 2 Diabetes: The PRISMA Study

Background: To evaluate whether structured self-monitoring of blood glucose (SMBG) is associated with changes in diabetes-specific quality of life (DSQoL) and locus of control (LOC) in patients with noninsulin-treated type 2 diabetes (T2DM). Study Design and Methods: In this analysis of the PRISMA (Prospective Randomized Trial on Intensive SMBG Management Added Value in Noninsulin-Treated T2DM Patients) Study psychosocial data, we evaluated the impact of 12 months of structured SMBG on the individual domains of DSQoL and LOC questionnaires, including the role of selected confounders. Results: The score for Satisfaction, Impact, and Worry domains (DSQoL) improved when compared with baseline, without significant differences between structured SMBG regimen (intervention group, n = 501) and active control group (n = 523). Scores for Internal, Chance, and Powerful Others domains (LOC) improved compared with baseline, with a significant between-group change in Chance (P = 0.0309). For DSQoL domain score, improvements were associated with higher number of SMBG measurements (P = 0.007), older age (P = 0.013), and male sex (P = 0.0133) for Satisfaction and with male sex (P &lt; 0.0001) for Worry. Concerning LOC domain score, improvements were associated with longer diabetes duration (P = 0.0084) and younger age (P &lt; 0.0001) for Chance and total number of SMBG measurements (P = 0.0036) for Internal, with the intervention group close to being significant (P = 0.06). Conclusions: Our analysis demonstrates that in patients with noninsulin-treated T2DM, structured SMBG is not associated with a deterioration of quality of life and LOC, which is strongly predicted by demographics and diabetes-related variables. These findings should be considered when tailoring educational support to SMBG for these patients

Thermal noise reduction for present and future gravitational wave detectors

Thermal noise in mirror suspension is and will be the most severe fundamental limit to the low-frequency sensitivity of interferometric gravitational wave detectors currently under construction. The technical solutions, adopted in the Virgo detector, optimize the current suspension scheme, but new materials and new designs are needed to further reduce the suspension thermal noise. Silicon fibers are promising candidates both for room temperature advanced detectors and for future cryogenic interferometric detectors

Heritability and Demographic Analyses in the Large Isolated Population of Val Borbera Suggest Advantages in Mapping Complex Traits Genes

Isolated populations are a useful resource for mapping complex traits due to shared stable environment, reduced genetic complexity and extended Linkage Disequilibrium (LD) compared to the general population. Here we describe a large genetic isolate from the North West Apennines, the mountain range that runs through Italy from the North West Alps to the South.The study involved 1,803 people living in 7 villages of the upper Borbera Valley. For this large population cohort, data from genealogy reconstruction, medical questionnaires, blood, anthropometric and bone status QUS parameters were evaluated. Demographic and epidemiological analyses indicated a substantial genetic component contributing to each trait variation as well as overlapping genetic determinants and family clustering for some traits.The data provide evidence for significant heritability of medical relevant traits that will be important in mapping quantitative traits. We suggest that this population isolate is suitable to identify rare variants associated with complex phenotypes that may be difficult to study in larger but more heterogeneous populations

SERVIÇO HOSPITALAR DE LIMPEZA E ABSENTEÍSMO: DOENÇA NO TRABALHO

RESUMO O estudo objetivou analisar a relação entre o absenteísmo-doença, o perfil sociodemográfico e laboral, os hábitos e a saúde dos trabalhadores do serviço hospitalar de limpeza. Estudo transversal envolvendo 157 trabalhadores do Serviço de Limpeza Hospitalar de um hospital universitário público do Rio Grande do Sul, Brasil. Predominou trabalhadores do sexo feminino, com ensino médio completo, casados/com companheiro, até três filhos. As faltas ao trabalho prevaleceram até nove dias. Os trabalhadores que mais faltaram foram os que tinham até três filhos (53,5%), com renda per capita familiar < 01 salário mínimo (52,4%), que não possuíam outro emprego (43,9%) e estavam acima do peso normal (71,4%). Evidenciou-se associação estatística entre absenteísmo-doença e ter filhos, sofrer acidente de trabalho, não ter tempo para lazer, necessidade de atendimento médico no último ano, suspeição para o alcoolismo, baixa capacidade para o trabalho e dor musculoesquelética

Monocrystalline fibres for low thermal noise suspension in advanced gravitational wave detectors

Thermal noise in mirror suspension will be the most severe fundamental limit to the low-frequency sensitivity of future interferometric gravitational wave detectors. We propose a new type of materials to realize low thermal noise suspension in such detectors. Monocrystalline suspension fibres are good candidates both for cryogenic and for ambient temperature interferometers. Material characteristics and a production facility are described in this paper

Avaliação científica do risco de extinção da fauna brasileira – resultados alcançados em 2012

Artigo retirado do ar a pedido dos autores - justificativa no arquivo pdf