Анализ механических состояний силовых систем. Сообщение 1. Предельное состояние

Изложены основы теории предельных состояний силовых систем, которые работают в условиях сложного нагружения (механическая усталость, трение и изнашивание, температура, электрохимическая коррозия). Получен энергетический критерий предельного состояния и описаны методы определения его параметров. Записаны условия прочности с учетом как циклической, так и контактной нагрузок.Викладено основи теорії граничних станів силових систем, що працюють в умовах складного навантаження (механічна утома, тертя та спрацьовування, температура, електрохімічна корозія). Отримано енергетичний критерій граничного стану та описано методи визначення його параметрів. Записано рівняння міцності з урахуванням як циклічного, так і контактного навантажень.Fundamentals of the theory of ultimate states in force systems operating under complex loading (mechanical fatigue, friction and wear, temperature, and electrochemical corrosion) have been described. Energy criterion of an ultimate state has been obtained and methods for calculating its parameters are given. Strength conditions taking into account both cyclic and contact loads are described

All that glisters is not gold: a comparison of electronic monitoring versus filled prescriptions – an observational study

BACKGROUND: Poor compliance with antihypertensive medication is assumed to be an important reason for unsatisfactory control of blood pressure. Poor compliance is difficult to detect. Each method of measuring compliance has its own strengths and weaknesses. The aim of the present study was to compare patient compliance with antihypertensive drugs as measured by two methods, electronic monitoring versus refill compliance. METHODS: 161 patients with a diagnosis of hypertension for at least a year prior to inclusion, and inadequate blood pressure control (systolic blood pressure ≥ 160 mmHg and/or diastolic blood pressure ≥ 95 mmHg) despite the use of antihypertensive drugs, were included. Patients' pharmacy records from 12 months prior to inclusion were obtained. Refill compliance was calculated as the number of days for which the pills were prescribed divided by the total number of days in this period. After inclusion compliance was measured with an electronic monitor that records time and date of each opening of the pillbox. Agreement between both compliance measures was calculated using Spearman's correlation coefficient and Cohen's kappa coefficient. RESULTS: There was very little agreement between the two measures. Whereas refill compliance showed a large range of values, compliance as measured by electronic monitoring was high in almost all patients with estimates between 90% and 100%. Cohen's kappa coefficient was 0.005. CONCLUSION: While electronic monitoring is often considered to be the gold standard for compliance measurements, our results suggest that a short-term electronic monitoring period with the patient being aware of electronic monitoring is probably insufficient to obtain valid compliance data. We conclude that there is a strong need for more studies that explore the effect of electronic monitoring on patient's compliance