Preheat Train Crude Distillation Fouling Propensity Evaluation by the Ebert and Panchal Model

The Ebert and Panchal fouling model was used to assess the fouling tendency of the exchangers of an industrial crude distillation unit (CDU) preheat train. The ranking obtained through a monitoring and processing of the performances of the different exchangers matched quite well the predictions of the Ebert and Panchal fouling model. In the meantime, a first mitigation solution consisted in periodically cleaning heat exchangers and installing TURBOTALTM tube inserts. Through the fouling monitoring of the equipped exchangers, the beneficial action of the TURBOTALTM inserts is also made quite clear

Environmental Impacts of Tartaric Stabilisation Processes for Wines using Electrodialysis and Cold Treatment

The environmental impacts of the two tartaric stabilisation methods used for wines, electrodialysis andcold treatment, were studied by determining water consumption (for the process and cleaning), wasteproduced (organic load and the composition of wastewater and residues) and energy consumption, atthe pilot stage and in wineries. Thanks to an online treatment of electrodialysis brines by reverse osmosis(industrial facility that treats 30 hL wine/h), the recycling of permeates led to a 65% reduction in waterconsumption, the volume of which represented only 3.9% of the wine treated. When washing and cleaningwater from the ED-RO system was taken into account, overall water consumption was 5.5 L/hL wine. Thepresence of ethanol, due to an osmotic phenomenon with no loss of wine volume, and tartaric acid in thebrines contributes to the organic load of the brine, with a COD of close to 8.4 g O2/L. Overall electricalenergy consumption for stabilisation by electrodialysis (0.21 kWh/hL) turned out to be eight times lowerthan that of cold stabilisation. An evaluation of cold stabilisation effluents revealed that 66.6% of the CODdischarged came from the diatomaceous earth (DE), 21.8% from the washing of the filter and 11.4% fromthe washing of the cold treatment tank. The production of used DE was 2.64 g (wet weight)/L of wine, andthe ethanol present in the DE waste represented a loss in wine volume of 0.14 L/hL

Radio(chemo)therapy in Elderly Patients with Esophageal Cancer: A Feasible Treatment with an Outcome Consistent with Younger Patients

BACKGROUND: Although the prevalence of esophageal cancer increases in elderly patients, its clinical history and outcome after treatment remain poorly described. METHODS: Between January 2001 and December 2011, 58 patients (pts) older than 75 years received 3D-conformal radiotherapy (mean dose 51 Gy) in two French cancer centers. 47/58 (82%) patients received concomitant chemotherapy (with CDDP and/or FU regimens) and 8 patients underwent surgery after primary radiochemotherapy (RCT). RESULTS: Median age was 77.9 years and the performance status (PS) was 0 or 1 in 89%. Tumors were mainly adenocarcinoma of lower esophagus or gastroesophageal junction (n = 51, 89%), T3T4 (n = 54, 95%), and N1 (n = 44, 77%). The mean follow-up was 21.9 months. In the overall population, the median progression-free survival was 9.6 months and median overall survival (OS) was 14.5 months. Using univariate analysis, OS was significantly associated with age (p = 0.048), PS (p < 0.001), and surgery (p = 0.035). 35 (60.3%) and 18 patients (31%) experienced grade 1-2 or 3-4 toxicity, respectively (CTCAE v4.0). CONCLUSION: Radiochemotherapy in elderly patients is a feasible treatment and its outcome is close to younger patient's outcome published in the literature. Surgical resection, after comprehensive geriatric assessment, should be recommended as the standard treatment for adenocarcinoma of lower esophagus or gastroesophageal junction in elderly patients with good PS and low co-morbidity profile, as it is in younger patients

Wireless networks and EMF-paving the way for low-EMF networks of the future: the LEXNET project

While, according to the World Health Organization, no adverse health effects of radio-frequency (RF) electromagnetic fields (EMFs) have been established to date, EMF exposure from wireless communication networks is nonetheless often cited as a major cause of public concern and is frequently given considerable media coverage. This article presents the results of a new survey on RF-EMF exposure risk perception together with a comprehensive overview of the EMF footprint of existing and emerging networks. On the basis of these findings, we then put forward the rationale for EMF-aware networking. Subsequently, we highlight the gaps in existing systems, which impede EMF-aware networking, and outline the key concepts of the recently launched European Union (EU) Seventh Framework Programme (FP7) Integrated Project Low-EMF Exposure Future Networks (LEXNET): a new, all-encompassing, population-based metric of exposure and ways it can be used for low-EMF, quality of service (QoS)-aware network optimization.This paper reports work undertaken in the context of the project LEXNET. LEXNET is a project supported by the European Commission in the 7th Framework Programme (GA n°318273). For further information, please visit www.lexnet-project.e

Scientific Opinion on the safety and efficacy of Urea for ruminants

Urea supplementation to feed for ruminants provides non-protein nitrogen for microbial protein synthesis in the rumen and thus in part replaces other dietary protein sources. Urea supplementation of feed for ruminants at doses up to 1 % of complete feed DM (corresponding to 0.3 g/kg bw/day) is considered safe when given to animals with a well adapted ruminal microbiota and fed diets rich in easily digestible carbohydrates. Based on the metabolic fate of urea in ruminants, the use of urea in ruminant nutrition does not raise any concern for consumers\u2019 safety. Urea is considered to be non irritant to skin and eyes and its topical use suggests that it is not a dermal sensitiser. The risk of exposure by inhalation would be low. The substitution of protein by urea in well balanced feed for ruminants would not result in an increased environmental nitrogen load. Urea is an effective source of non-protein nitrogen substituting for dietary protein in ruminants

Safety and efficacy of a natural mixture of dolomite plus magnesite and magnesium-phyllosilicates (Fluidol) as feed additive for all animal species

The additive, a natural mixture of dolomite plus magnesite and magnesium-phyllosilicates, is intended to be used as a technological additive (functional groups: anticaking agents) in feedingstuffs for all animal species. The additive is safe in complete feed for dairy cows, piglets and pigs for fattening at a maximum concentration of 20,000 mg/kg. No conclusions can be drawn for all the other animal species/categories. The additive is not genotoxic. As the additive is essentially not absorbed from the gut lumen, the Panel on Additives and Products or Substances used in Animal Feed considers that use of the additive in animal nutrition is safe for consumers of food products from animals fed diets containing the additive. The additive is not an irritant to the eyes and the skin, it is not a skin sensitiser and it is of low toxicity by the inhalation route. The components of the additive (dolomite, magnesite, talc and chlorite) are natural constituents of soil. Consequently, the use of the additive in animal nutrition will not pose a risk to the environment. The additive is effective as an anticaking agent at a minimum inclusion level of 5,000 mg/kg feed

Safety and efficacy of methylester of conjugated linoleic acid (t10,c12 isomer) for pigs for fattening, sows and cows

A mixture of methylated conjugated linoleic acid (CLA) isomers (t10,c12 and c9,t11) in equal proportions was not genotoxic and caused no reproductive toxicity. In a sub-acute study in dogs, a sub-chronic toxicity study in rats and a chronic study in dogs, no adverse effects were seen up to the highest levels tested. The maximum recommended feed concentration (5 g CLA (t10,c12)-ME from Lutalin (R)/kg feed for piglets, pigs for fattening and sows) or dose (30 g CLA (t10,c12)-ME from Lutrell (R) Pure/cow per day) is considered safe for target species. The CLA content of milk from cows treated with the highest recommended dose did not exceed background values (in milk of untreated cows) for both CLA isomers. An estimate of consumer exposure to both CLA isomers from food from pigs receiving 3 g of both CLA isomers/kg feed is <= 320 mg CLA isomers/person and day. This quantity corresponds to about 9% of the quantity considered safe for 6 months and is considered unlikely to raise concerns for consumer safety. Exposure of users by inhalation of the additive is likely to be minimal. Neither of the products under application, the liquid or the solid product, was tested as such for skin and eye irritation and skin sensitisation. The use of the additive in animal nutrition would not pose a risk to the environment. In pigs for fattening, CLA (t10,c12)-ME has a potential for improving feed to gain ratio. More consistent effects are a reduction in subcutaneous fat, an increase in intramuscular fat and fat firmness. No essential effects were found in sows. Administration of CLA to dairy cows reduces in a dose-dependent manner the fat content of milk, and milk fat yield. Energy balance in early lactation is improved by CLA (t10,c12)-ME; however, reproductive parameters were not influenced