241 research outputs found

    'Preaching the social gospel' : Methodist pacifism, 1935-1945

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    This thesis is a study of pacifism in the Methodist Church during the 1930's and World War 11. It concentrates particularly on the nature of Methodist Pacifism at this time. This was based on Christian pacifism, the social gospel and secular pacifism. The pacifist philosophy of some Methodists caused them to act in particular ways and elicited a particular response from their Church. These actions and this response developed as a result of the experience of the thirties and intensified at the outbreak of World War 11 in September 1939. The first two chapters seek to establish the nature of Methodist pacifism and place it within the context of New Zealand and overseas experiences. The chapter on the Bible Class Movement examines its importance in the development of Methodist pacifism and chapter four demonstrates how pacifists in the Church used it as an organization to further achieve their aims. This chapter also touches on the Church's reaction to this pacifist pressure. The Church's lack of response prompted Methodist pacifists to establish a new peace group specifically for the growing body of Christian pacifists from the mainstream denominations. This group, the Christian Pacifist Society, is the subject of chapters five and six. With the outbreak of war, the Church attempted to reassert control over its pacifists by using the 1940 Manifesto on Peace and War to obtain their promise of silence. Chapter seven traces the Church’s attempts to control its pacifists ad the pacifist response to them. The final chapter quickly outlines the ostensible outcome of the surge ·of pacifist thought in th Methodist Church: the Methodist Conscientious Objector. The experience of Methodist objectors with their Church and in detention camps concludes this study. The number and fervour of Methodist pacifists in World War 11 can almost be seen as an aberration both within the Methodist Church and society. They were the outcome of the particular circumstances of the 1920’s and 1930’s and they had a strong effect on the Church during World War II. However, they had little effect on society and even the Church soon assimilated their ‘absolute’ pacifist views into a vague anti-nuclear pacifism

    High preoperative blood levels of HE4 predicts poor prognosis in patients with ovarian cancer

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    The aim of this study was to assess the clinical value of preoperative blood levels of HE4 as a predictor of overall survival in patients with ovarian cancer and to validate previous data of HE4 and the ROMA algorithm including HE4 and CA125 in discriminating benign and malignant ovarian tumors. Experimental design: The preoperative plasma levels of HE4 and CA125 were analyzed with ELISA in 312 patients with adnexal lesions. Tumors were classified as benign (n= 206), borderline (i.e. low malignant potential tumors) (n= 25), and well (n= 14), moderately (n= 15), and poorly (n= 51) differentiated malignant. Results: In univariate Cox regression analyses high levels (dichotomized at the median) of HE4, CA125, increased age (continuous variable), advanced-stage of disease 2-4, histological grade 3 and non-optimal tumor debulking at primary surgery were all significantly associated with shorter overall survival. A multivariate Cox regression model including pre-operative available covariates HE4 and CA125 both dichotomized at median in addition to age as continuous variable showed that high levels of HE4 was an independent prognostic marker for worse prognosis HR 2.02 (95% CI 1.1-3.8). In postmenopausal women the ROMA algorithm gave the highest AUC of 0.94 (95% CI, 0.90-0.97) which was higher than the separate markers HE4 AUC 0.91 (95% CI 0.86-0.95) and CA125 AUC 0.91(95% CI 0.87-0.96). Conclusions: High concentration of plasma HE4 is an independent preoperative marker of poor prognosis in patients with ovarian cancer. The algorithm ROMA discriminates in postmenopausal women between malignant and benign tumors with an AUC of 0.94

    Hopp om förbÀttring av överlevnad i ovarialcancer

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    Ovarian cancer is the most common cause of death from a gynecologic cancer. Every year around 700 women contracts ovarian cancer in Sweden. The overall survival is among the highest in Europe, but still long term relative survival is only 46%. It is a long-held myth that ovarian cancer is a disease without symptoms. Almost 90% of women have symptoms, even in the early stages. Symptoms that should arise suspicion of ovarian cancer and initiate diagnostic work-up are continuous abdominal extension, early feeling of satiety, pelvic or abdominal pain, urinary urge and postmenopausal bleeding. Women's awareness of symptoms and willingness to seek medical advice and the organization of the health care system are important factors determining cancer survival. Ovarian cancer is a heterogeneous group of diseases with different tumor traits and prognosis. Personalized medicine and preventive measures recognizing recent knowledge about tumor biology will positively affect survival

    Prevalence, symptoms and management of uterine fibroids: an international internet-based survey of 21,746 women

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    <p>Abstract</p> <p>Background</p> <p>In 2009 the Uterine Bleeding and Pain Women's Research Study (UBP-WRS) was conducted interviewing 21,479 women across 8 countries in order to gain patient-based prevalence data on uterine pain and bleeding indications and investigate uterine symptoms and women's treatment experiences. This article shows relevant results of the study for the indication uterine fibroids providing data on self-reported prevalence, symptomatology and management of uterine fibroids.</p> <p>Methods</p> <p>2,500 women (USA: 4,500 women) in each country (Brazil, Canada, France, Germany, Italy, South Korea, the UK, the USA) completed an online survey. Women included were in their reproductive age (age group 15-49 years; USA: 18-49 years) and had ever experienced menstrual bleedings. Quotas were applied for age, region, level of education and household income of respondents. Variables have been analyzed descriptively and exploratory statistical tests have been performed.</p> <p>Results</p> <p>The self-reported prevalence of uterine fibroids ranged from 4.5% (UK) to 9.8% (Italy), reaching 9.4% (UK) to 17.8% (Italy) in the age group of 40-49 years. Women with a diagnosis of uterine fibroids reported significantly more often about bleeding symptoms than women without a diagnosis: heavy bleedings (59.8% vs. 37.4%), prolonged bleedings (37.3% vs. 15.6%), bleeding between periods (33.3% vs. 13.5%), frequent periods (28.4% vs. 15.2%), irregular and predictable periods (36.3% vs. 23.9%). Furthermore women with diagnosed uterine fibroids reported significantly more often about the following pain symptoms: pressure on the bladder (32.6% vs. 15.0%), chronic pelvic pain (14.5% vs. 2.9%), painful sexual intercourse (23.5% vs. 9.1%) and pain occurring mid-cycle, after and during menstrual bleeding (31.3%, 16.7%, 59.7%, vs. 17.1%, 6.4%, 52.0%). 53.7% of women reported that their symptoms had a negative impact on their life in the last 12 month, influencing their sexual life (42.9%), performance at work (27.7%) and relationship & family (27.2%).</p> <p>Conclusions</p> <p>Uterine fibroid is a common concern in women at fertile age causing multiple bleeding and pain symptoms which can have a negative impact on different aspects in women's life.</p

    Radiotherapy Versus Inguinofemoral Lymphadenectomy as Treatment for Vulvar Cancer Patients With Micrometastases in the Sentinel Node: Results of GROINSS-V II

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    PURPOSE: The Groningen International Study on Sentinel nodes in Vulvar cancer (GROINSS-V)-II investigated whether inguinofemoral radiotherapy is a safe alternative to inguinofemoral lymphadenectomy (IFL) in vulvar cancer patients with a metastatic sentinel node (SN). METHODS: GROINSS-V-II was a prospective multicenter phase-II single-arm treatment trial, including patients with early-stage vulvar cancer (diameter < 4 cm) without signs of lymph node involvement at imaging, who had primary surgical treatment (local excision with SN biopsy). Where the SN was involved (metastasis of any size), inguinofemoral radiotherapy was given (50 Gy). The primary end point was isolated groin recurrence rate at 24 months. Stopping rules were defined for the occurrence of groin recurrences. RESULTS: From December 2005 until October 2016, 1,535 eligible patients were registered. The SN showed metastasis in 322 (21.0%) patients. In June 2010, with 91 SN-positive patients included, the stopping rule was activated because the isolated groin recurrence rate in this group went above our predefined threshold. Among 10 patients with an isolated groin recurrence, nine had SN metastases > 2 mm and/or extracapsular spread. The protocol was amended so that those with SN macrometastases (> 2 mm) underwent standard of care (IFL), whereas patients with SN micrometastases (≀ 2 mm) continued to receive inguinofemoral radiotherapy. Among 160 patients with SN micrometastases, 126 received inguinofemoral radiotherapy, with an ipsilateral isolated groin recurrence rate at 2 years of 1.6%. Among 162 patients with SN macrometastases, the isolated groin recurrence rate at 2 years was 22% in those who underwent radiotherapy, and 6.9% in those who underwent IFL (P = .011). Treatment-related morbidity after radiotherapy was less frequent compared with IFL. CONCLUSION: Inguinofemoral radiotherapy is a safe alternative for IFL in patients with SN micrometastases, with minimal morbidity. For patients with SN macrometastasis, radiotherapy with a total dose of 50 Gy resulted in more isolated groin recurrences compared with IFL

    ”Det kan vara svĂ„rt att förklara pĂ„ rader” : perspektiv pĂ„ analys och bedömning av multimodal textproduktion i Ă„rskurs 3

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    Drawing and coloring have been part of young students text making as  longas the writing system has been used, but with the increased use of digital tools and an enlarged focus on accountability of today there is a reinforced educational interest to understand what constitutes multimodal student texts in the context of classroom practice. This thesis project overall aim is to highlight and discuss the opportunities and difficulties in the assessment of language and knowledge-developing multimodal text work in a multilingual educational context.Conceptually the study is grounded in sociocultural theories, in sociosemiotic theory and in multiliteracies research. The methods used consist of qualitative multimodal text analysis and semi-structured interviews with students and their teacher.The three empirical studies were carried out, each having a different perspective. The first study looks at the text production of students in an integrated work of drawing, coloring and writing. The second study focuses how students reason when they choose to draw, write or both draw and write when they report to their teacher what they have learned. The third study discusses what the teacher highlights when assessing her students’ multimodal text productions. Overall, the results show that the semiotic resources, images and color, dominate students’ text productions and that the teacher attaches great importance to the illustrations, but that she, despite the best intentions, has trouble using multimodal criteria when assessing the students’ different ways of expressions and semiotic resources into a whole. It seems to be problematic for the teacher to allow students to freely interpret and independently design the task while she at the same time intends to make an overall assessment of how the content is presented. The results also indicate that it is difficult  for  the  students  to  verbalize  their  thoughts on the assessment and in practice; the teacher more often is focused on assessing abilities relating to how thoroughly the students carry out the process of documenting rather than encouraging the students to develop and express their knowledge. Finally, the thesis concludes with discussing the content of an ongoing need for research, especially regarding the consequences it may have for younger students, whatever language background they have.Ytterligare delarbetenBorgfeldt, E., &amp; Lyngfelt, A. (2017). ”Jag ritade först sen skrev jag”. Elevperspektiv pĂ„ multimodal textproduktion i Ă„rskurs 3. Forskning om undervisning och lĂ€rande 2017: 1 vol. 5, s. 64-88. http://www.forskul.se/tidskrift/nummer18/jag_ritade_forst_sen_skrev_jag_ __elevperspektiv_pa_multimodal_textproduktion_i_arskurs_3Borgfeldt, E. (2017).Multimodal textproduktion i Ă„rskurs 3 – analys av en lĂ€rares bedömning. Educare: 2017: 1, s. 118-151. Malmö: LĂ€rande och samhĂ€lle, Malmö högskola. https://www.mah.se/upload/FAKULTETER/LS/Dokument%20LS/Educa re%2017.1%20muep.pdf</p

    The Southerners, JSC Marching Band, with Drum Major Freddie Pollard and Featured Twirlers Jerry Hill and Sharon Holland

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    A postcard depicts the Jacksonville State College 1965-1966 Southerners Marching Band members standing outside a campus building with the Alabama Jacksonville State College banner. Drum Major was Freddie Pollard and featured twirlers were Jerry Hill and Sharon Holland.https://digitalcommons.jsu.edu/lib-ac-histimg/49004/thumbnail.jp
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