Morpholine and its derivatives as vapour phase corrosion inhibitors for mild steel

Morpholine and its derivatives such as carbonate, borate and phosphate were synthesized llnd evaluated as vapour-phase corrosion inhihitors (VPIs) for mild steel usin~ wei~ht loss and visual observation methods under continuous condensation test (CCT). From the results the perfornlance of mOI"pholine and its derivatives as VI'I for mild steel is comparatively a'isessed

The THREAT-ARREST Cyber-Security Training Platform

Cyber security is always a main concern for critical infrastructures and nation-wide safety and sustainability. Thus, advanced cyber ranges and security training is becoming imperative for the involved organizations. This paper presets a cyber security training platform, called THREAT-ARREST. The various platform modules can analyze an organization’s system, identify the most critical threats, and tailor a training program to its personnel needs. Then, different training programmes are created based on the trainee types (i.e. administrator, simple operator, etc.), providing several teaching procedures and accomplishing diverse learning goals. One of the main novelties of THREAT-ARREST is the modelling of these programmes along with the runtime monitoring, management, and evaluation operations. The platform is generic. Nevertheless, its applicability in a smart energy case study is detailed

Therapeutic Challenge with a CDK 4/6 Inhibitor Induces an RB-Dependent SMAC-Mediated Apoptotic Response in Non-Small Cell Lung Cancer.

Purpose: The retinoblastoma tumor suppressor (RB), a key regulator of cell-cycle progression and proliferation, is functionally suppressed in up to 50% of non-small cell lung cancer (NSCLC). RB function is exquisitely controlled by a series of proteins, including the CyclinD-CDK4/6 complex. In this study, we interrogated the capacity of a CDK4/6 inhibitor, palbociclib, to activate RB function. Experimental Design and Results: We employed multiple isogenic RB-proficient and -deficient NSCLC lines to interrogate the cytostatic and cytotoxic capacity of CDK 4/6 inhibition in vitro and in vivo We demonstrate that while short-term exposure to palbociclib induces cellular senescence, prolonged exposure results in inhibition of tumor growth. Mechanistically, CDK 4/6 inhibition induces a proapoptotic transcriptional program through suppression of IAPs FOXM1 and Survivin, while simultaneously augmenting expression of SMAC and caspase-3 in an RB-dependent manner. Conclusions: This study uncovers a novel function of RB activation to induce cellular apoptosis through therapeutic administration of a palbociclib and provides a rationale for the clinical evaluation of CDK 4/6 inhibitors in the treatment of patients with NSCLC

Extreme Learning Machine for Microarray Cancer Classification

Cancer is a diseases in which a set of cells has not able controlled their growth, attack that interrupts upon and destroy the nearest tissues or spreading to other locations in the body. Cancer has become one of the perilous diseases in the present scenario. In this paper, the recently developed Extreme Learning Machine is used for classification problems in cancer diagnosis area. ELM is an available learning algorithm for single layer feed forward neural network. The advanced and developed methodology known for cancer multi classification using ELM microarray gene expression cancer diagnosis, this used for directing multi category classification problems in the cancer diagnosis area. ELM avoids many problems, improper learning rate and over fitting commonly faced by iterative learning methods and completes the training very fast. The performance of classification ELM on three benchmark microarray data for cancer diagnosis, namely Lymphoma data set, Leukemia data set, SRBCT data set. The results of experiments with RVM and ELM shows that for many categories of ELM still outperformer with RVM. DOI: 10.17762/ijritcc2321-8169.15018

GSM Based Generator Monitoring System for Steel Melting Shop

Steel making processes are highly energy intensive and comprised of many complex unit operations. Iron ore and coal need preprocessing before feeding into a reactor, and molten metal from different reactors needs to be carefully drawn into a solid metal and then rolled into sheets. Each of these operations has a stake in the quality of steel produced, and needs constant monitoring and need continuous power supply for fabrication. If a power failure occurs the production will be stopped, time delay increases for finishing fabrication. In some cases we can loss consumer due to unsatisfactory. My Project focuses the detection of power failure and takes reflex action to solve the problem with help of modem communication using GSM. The power failure will be intimated to the Microcontroller it drive the GSM modem to send a text message to the concern person mobile number which was already programmed in Microcontroller and also monitoring the parameter are temperature, oil level, fuel level and when they exceed predefined limits an automatically intimated to authorized person and also This system can be designed to send SMS alerts whenever the Circuit Breaker (Relay) trips and simulation result done by using LabVIEW software

Pressure Swing Adsorption Based Air Filtration/Purification Systems for NBC Collective Protection

The respiratory protection against chemical warfare agents (CWA) has become a worldwide security concern in light of the many recent international threats utilising CWA. Till date the carbon filtration was adequate to protect the soldiers from the threats of CWA. With the advent of further advancements in the CWA a new threat is looming large that is known as the carbon breakers. pressure swing adsorption (PSA) is a well-established gas separation technique in air separation, gas drying, and hydrogen purification separation. Recently, PSA technology has been applied in the area of chem-bio defence by virtue of its unique advantages. This article reviews recent advances and developments in the field of PSA based purification, separation, and its use in defense sector. This emerging and advanced PSA technology can provide regenerative nuclear, biological and chemical (NBC) collective protection for ground vehicles, aircraft, ships and shelters. This PSA technology challenges threat scenario developed which includes nerve, blood and blister agents, as well as a “carbon breaker” agent, and proved that this technology will be a viable concept for future NBC collective protection systems. New technological breakthroughs and greater sophistication of PSA technologies will transform the collective protection based PSA technology in real field sense, addressing the escalating threat of CWA. We conclude this review with future prospects and challenges associated with PSA technology

HETEROSIS STUDIES FOR FIBRE QUALITY TRAITS IN DIALLEL CROSSES OF UPLAND COTTON (GOSSYPIUM HIRSUTUM L.)

Diallel analysis was studied by involving nine parents and their seventy two cross combinations in upland cotton to investigate the best heterotic crosses for fibre quality traits. The hybrid Anjali x KC 2 recorded both highest positive significant relative heterosis (17.18%) and heterobeltiosis (11.81%) and hybrid MCU 5 x Surabhi exhibited highest positive significant standard heterosis (16.98%) for bundle strength. 2.5% span length in parents and their hybrids ranged from 24.03 to 33.51 mm and 27.31 to 36.90 mm, respectively. Thirty four hybrids showed significant negative heterotic effects for micronaire value and hybrid MCU 5 x KC 3 (-27.89%) displayed greater negative standard heterosis. Mean performance of elongation per cent in parents and hybrids was 5.11% and 4.87%, respectively. Out of seventy two hybrids, six cross combinations viz., KC 2 x MCU 5, MCU 5 x MCU 7, Anjali x Suraj, Anjali x MCU 5, Surabhi x Anjali and KC 2 x Suraj were appeared to more promising for most of the fibre quality traits and could be exploited. The present study reveals good scope for isolation of pure lines from the progenies of heterotic F1’s as well as commercial exploitation of heterosis in upland cotton

Evaluation of oryzalin-induced putative polyploids of Jasminum sambac cv. Ramanathapuram Gundumalli

The aim of the research was to create genetic variations in Jasminum sambac using oryzalin as a polyploidizing agent. Rooted stem cuttings of J. sambac were treated with oryzalin (0.005, 0.01 and 0.05%) and their vegetative and flowering parameters were recorded on 150 days after treatment. The study revealed that the higher concentration of oryzalin (0.05%) caused reduction in plant height, internodal length, number of flowering cymes per plant and number of flower buds per cyme. However, the same treatment significantly enhanced certain vegetative parameters viz., number of secondary branches, stem girth, number of leaves and leaf area, and flowering parameters namely flower bud length, corolla tube length, flower bud girth, diameter of open flower and hundred flower bud weight. High GCV was recorded in major yield attributing traits, i.e. number of flowering cymes per plant and hundred flower bud weight. High heritability and genetic advance registered for the traits viz., plant height, number of secondary branches, internodal length, number of flowering cymes, flower bud girth and hundred flower bud weight per plant indicates least influence by environment and selection such characters may be useful

A PROSPECTIVE STUDY ON RISK FACTORS OF IRON DEFICIENCY ANEMIA IN PREGNANT WOMEN AND THEIR MANAGEMENT

Objective: Iron deficiency anemia during pregnancy leads to preterm birth, low birth weight and increases the incidence of postpartum hemorrhage (PPH) and the reason for the incidence of PPH is higher in India compared with the rest of the world. In this study, our main goal was to find out the risk factors and complications of iron deficiency anemia and their management in pregnant women. Methods: It is a prospective study done at Obstetrics and Gynecology Department in Government District Headquarters Hospital, Tiruppur. All subjects were analyzed in full detail and hemoglobin estimation was also done to the patients. Results: Study found that 52% shows moderate anemia followed by 30% mild and 18% severe, respectively. Risk factors are found in 55% cases. Study found an association between risk factors and severity of anemia. Conclusion: Iron deficiency anemia continues to be the commonest etiology of anemia in pregnancy. The prevalence of iron deficiency in a pregnant woman is amongst the highest in the world. Untreated iron deficiency has significant adverse feto-maternal consequences. Iron supplementation and antenatal care are the basic requirements to prevent anemia

Genetic variability studies on yield attributing traits in Palmyrah (Borassus flabellifer L.): Implications for crop improvement

Palmyrah is a dioecious palm, which is known for its resilience in arid and semi-arid environments. It is used to produce numerous edible and non-edible products. The association among yield-related traits and their pattern of influence are useful in evaluating and planning the selection criteria for desirable traits. The aim of this study was to examine the genetic variability and character association among the Palmyrah genotypes. A total of thirty accessions of Palmyrah were used for this study. Eleven traits contributing to growth and yield were recorded and analysed for genetic variability, correlation and path analysis. The number of bunches, single fruit weight and fruit yield per palm recorded the higher estimates of GCV and PCV. Among the eleven traits, 10 traits showed high heritability and GAM, whereas the trunk girth showed high heritability and moderate GAM. Fruit yield per palm exhibited positive correlation with trunk girth, number of bunches, number of fruits per bunch and single fruit yield. Path coefficient analysis revealed that the traits like number of bunches and single fruit weight had a positive and high direct effect on fruit yield per palm. Based on these results, Palmyrah improvement programme could be accelerated by selecting the variables that have a stronger correlation to fruit yield per palm and moderate to high estimates of PCV, GCV, heritability and high genetic advancement