TLS data for architectural 2D representation and 3D modeling. Different approaches tested in the case of San Giovanni in Saluzzo (Cn) Italy

TLS (Terrestrial Laser Scanners) data today represents one of the most attractive ways to face the metric survey of an architectural object. When a restoration project is needed not many restorers are used to managing 3D models and traditional graphic results such as plans and sections are usually required. The paper defines a correct balance between the use of traditional (manual and total station) and TLS techniques in order to satisfy the usual requirements for the metric survey of an architectural object in order to obtain a complete 2D documentation of the San Giovanni Church in Saluzzo (Cn) - Italy that would be used for the restoration both of the decorative apparatus and of the structure of the church. Furthermore using the acquired 3D data some tests on commercial and open-source software for 3D modeling purpose are realised. The paper deals first of all with the followed methodology for the 2D documentation starting from 3D data. Moreover an analysis and a comparison between different software packages for the 3D modeling phase is reporte

ASSESSING TERRESTRIAL MMS 3D DATA FOR OUTDOOR MULTI-SCALE MODELLING

Mobile Mapping Systems (MMS) have recently benefited from the development of many fusion-based technologies with countless systems development based on cars, drones, trolley, wearable or portable mapping system. The scale of applicating range from the urban to the architectural scale. Recent solution are also based on visual or Lidar SLAM (Simultaneous Localization and Mapping), which substantially takes advantage of environmental features and techniques of continuous co-registration of the clouds, also in case of absence on GNSS positioning measurement. FARO Technology has recently developed the Swift, a fusion-based hybrid solution that integrates the sensors for 3D mapping in a trolley system configuration and recently, an external camera Panocam Theta Z1 is equipping the system enabling the possibility to associate radiometry to the acquired data. The working principle is the exploitation of a system of static and mobile configuration, using the so-called “anchor scans” co-registration as an hybrid intermediate solution between a typical static scan and a profilometers-based MMS point cloud. The co-registered clouds therefore yield a trajectory mode such as SLAM but benefit from the comparable range and density characteristics, according to user-customized settings, of static scans, with a duration of a few seconds per scan and a few minutes overall. In the present research the Swift System is tested in two different context and the assessment are conducted aimed at satisfying both the urban and the architectural scale instances in the direction of improving further evaluations

A new indoor LiDAR-based MMS challenging complex architectural environments

The use of moving devices equipped with range- and image-based sensor, generically defined Mobile Mapping systems (MMS), have been quite a disruptive innovation in the development of Geomatics techniques for 3D surveying large indoor-outdoor spaces and offer multiple solutions. The recent expansion of portable devices in the form of trolleys, backpacks, handheld tools largely implements SLAM (Simultaneous Localization and Mapping) algorithms and technology based on both Lidar and/or visual solutions for answering to the positioning and the 3D reconstruction problems. The research on MMS is directed to improve both multi-sensor integration implementation and usability of systems in diversified use contexts and application fields. The aim of the presented research is the evaluation of the potential of the Swift system recently developed by FARO Technologies, that has been fine-tuned for regular and large extent interiors mapping (such as factories, hospitals, airports, offices). The work tries to preliminary investigate the data delivery and usability of the integrated system. This is based on three elements mounted on a sliding trolley moved by the operator walking: the ScanPlan profilometer working for the 2D SLAM mapping, the static TLS Focus S-series, and the smartphone managing the sensors operation and the acquisition progress. The evaluation strategy undertaken will be based on the global and local performance analysis related to the trajectory, the data accuracy, the metric content and consistency. Two test studies belonging to the 20th century. architecture are presented in a preliminary framework of evaluation and validation: a Liberty-style cinema and the Torino Esposizioni Hall B designed in ferrocement by pier Luigi Nervi

Prevalência de obesidade na infância em diferentes agrupamentos sociais e a importância de estratégias pedagógicas

The subject of this research was the prevalence of obesity in children, from 6 to 8 years old attending the first-grade of 'Fundamental Teaching', in different social groups, in Santa Maria, RS. The study included 424 children (212 girls and 212 boys) distributed in the following groups: group 1 (central area, middle class), group 2 (suburban area, middle class), and group 3 (suburban area, poor class). Height and weight were measured in all the children. Overweight and obesity was defined by body mass index (BMI, kg/m2) of 85-95th percentile and > 95th percentile, respectively, according to the NCHS. Data are reported as frequencies and compared by chi2 test (p 95, respectivamente. A referência utilizada foi do NCHS. Para a análise dos dados utilizou-se a estatística descritiva e chi2 (p < 0,05). Os resultados mostram uma prevalência de obesidade de 29,95% na amostra e semelhança entre agrupamentos e gêneros. A presença de sobrepeso e obesidade no início da idade escolar reforça a importância de hábitos saudáveis na infância, tanto na alimentação como na prática sistemática de atividades motoras

A DINÂMICA FLUVIAL DO RIO ACRE: UMA ANÁLISE AMBIENTAL DO TRECHO URBANO DA CIDADE DE RIO BRANCO-AC: The fluvial dynamics of river Acre: An environmental analysis in urban section of the city of Rio Branco-AC

Estudos que abordam a dinâmica fluvial em bacias hidrográficas são considerados de extrema importância por discutir seu funcionamento natural ou alterado por ações antrópicas. O objetivo desse estudo foi analisar a dinâmica Geofluvial da área urbana do rio Acre. Para alcançar este propósito, o estudo foi baseado nas técnicas de Christoffoletti (1980) e da pesquisa de campo que ocorreu no mês de dezembro de 2017. Através destas medidas foi possível observar os aspectos físicos, ambientais e sociais que estão ocorrendo as margens do rio Acre. &nbsp;Neste sentido, foi possível compreender que o rio Acre é um rio capaz e competente, que tem os seus processos alterados pela presença da urbanização em suas margens

Violacein treatment modulates acute and chronic inflammation through the suppression of cytokine production and induction of regulatory T cells

FAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOCNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOInflammation is a necessary process to control infection. However, exacerbated inflammation, acute or chronic, promotes deleterious effects in the organism. Violacein (viola), a quorum sensing metabolite from the Gram-negative bacterium Chromobacterium violaceum, has been shown to protect mice from malaria and to have beneficial effects on tumors. However, it is not known whether this drug possesses anti-inflammatory activity. In this study, we investigated whether viola administration is able to reduce acute and chronic autoimmune inflammation. For that purpose, C57BL/6 mice were intraperitoneally injected with 1 mu g of LPS and were treated with viola (3.5mg/kg) via i.p. at the same time-point. Three hours later, the levels of inflammatory cytokines in the sera and phenotypical characterization of leukocytes were determined. Mice treated with viola presented a significant reduction in the production of inflammatory cytokines compared with untreated mice. Interestingly, although viola is a compound derived from bacteria, it did not induce inflammation upon administration to naive mice. To test whether viola would protect mice from an autoimmune inflammation, Experimental Autoimmune Encephalomyelitis (EAE)-inflicted mice were given viola i.p. at disease onset, at the 10th day from immunization. Viola-treated mice developed mild EAE disease in contrast with placebo-treated mice. The frequencies of dendritic cells and macrophages were unaltered in EAE mice treated with viola. However, the sole administration of viola augmented the levels of splenic regulatory T cells (CD4+ Foxp3+). We also found that adoptive transfer of viola-elicited regulatory T cells significantly reduced EAE. Our study shows, for the first time, that violacein is able to modulate acute and chronic inflammation. Amelioration relied in suppression of cytokine production (in acute inflammation) and stimulation of regulatory T cells (in chronic inflammation). New studies must be conducted in order to assess the possible use of viola in therapeutic approaches in human autoimmune diseases.Inflammation is a necessary process to control infection. However, exacerbated inflammation, acute or chronic, promotes deleterious effects in the organism. Violacein (viola), a quorum sensing metabolite from the Gram-negative bacteriumChromobacterium vio105116FAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOCNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOFAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOCNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOFAPESP [2011/17965-3]CNPq [471066/2012-5]FAPESP [2014/02631-0, 2011/23664-6, 2012/01892-0]2011/17965-3; 471066/2012-5; 2014/02631-0; 2011/23664-6; 2012/01892-0sem informaçã

AVALIAÇÃO DA QUALIDADE DE COMPRIMIDOS DISPENSADOS EM UMA FARMÁCIA PÚBLICA DO NOROESTE DO RIO GRANDE DO SUL

O controle de qualidade é um processo importante após o preparo de medicamentos e deve abranger todas as etapas da produção. Desvios na qualidade de um medicamento podem causar diversos danos à saúde do paciente. O Sistema Único de Saúde (SUS) conta com distribuição gratuita de medicamentos para a população e a aquisição desses medicamentos é feita através de licitações. Nesse sentido, o objetivo deste trabalho foi realizar testes físico-químicos de controle de qualidade de comprimidos dispensados em uma Farmácia Pública de um município do noroeste do Rio Grande do Sul. Foram fornecidos pela Farmácia Pública, os seguintes medicamentos: furosemida 40 mg, enalapril de 10 mg e propranolol 40 mg. Os testes realizados foram: análise do aspecto físico, peso médio, friabilidade, tempo de desintegração e doseamento. A furosemida foi reprovada no teste do peso médio e aprovada nos demais testes. Já o propranolol foi reprovado no ensaio de doseamento, encontrando-se abaixo das especificações. O enalapril apresentou conformidade em todos os testes realizados. Esses resultados demonstram que os medicamentos podem comprometer a saúde do usuário do Sistema público e que esses requisitos podem ser utilizados para qualificar os fornecedores que participam dos processos licitatórios

Crescimento de prematuros durante internação em unidade de tratamento intensivo neonatal / Growth of prematures during hospitalization in unit neonatal intensive care

O crescimento de recém-nascidos pré-termo no período neonatal é uma das preocupações da equipe neonatal, especialmente porque está relacionado ao neurodesenvolvimento. O objetivo deste trabalho foi avaliar o crescimento de recém-nascidos pré-termo durante a internação neonatal. Foram incluídos 51 recém-nascidos pré-termo internados na Unidade de Tratamento Intensivo Neonatal de Hospital do Sul do Brasil. As variáveis peso, comprimento e perímetro cefálico foram aferidas em 4 momentos: ao nascer, na liberação da via oral, na via oral plena e na alta hospitalar. A avaliação do crescimento teve por referência as curvas de Fenton.  Ao nascer 53% eram do sexo masculino, com idade gestacional de 33,6(±1,5) semanas e 71% eram adequados para idade gestacional.  Peso menor que percentil 10° da referência foi observado em 25% dos pré-termos ao nascer, havendo aumento para 57% na alta hospitalar (p&lt;0,001). Não houve diferença percentual significativa para o comprimento e o perímetro cefálico. Conclui-se que, apesar do crescimento no comprimento e Perímetro cefálico ter sido satisfatório, o peso não acompanhou ganho suficiente para se manter dentro da normalidade durante a internação neonatal, apontando para a importância da adoção de um protocolo de nutrição sistematizado, a fim de evitar a desnutrição no período e pós-natal

Impact of social determinants on antiretroviral therapy access and outcomes entering the era of universal treatment for people living with HIV in Italy

Background: Social determinants are known to be a driving force of health inequalities, even in high income countries. Aim of our study was to determine if these factors can limit antiretroviral therapy (ART) access, outcome and retention in care of people living with HIV (PLHIV) in Italy. Methods: All ART naïve HIV+ patients (pts) of Italian nationality enrolled in the ICONA Cohort from 2002 to 2016 were included. The association of socio-demographic characteristics (age, sex, risk factor for HIV infection, educational level, occupational status and residency area) with time to: ART initiation (from the first positive anti-HIV test), ART regimen discontinuation, and first HIV-RNA &lt; 50 cp/mL, were evaluated by Cox regression analysis, Kaplan Meier method and log-rank test. Results: A total of 8023 HIV+ pts (82% males, median age at first pos anti-HIV test 36 years, IQR: 29-44) were included: 6214 (77.5%) started ART during the study period. Women, people who inject drugs (PWID) and residents in Southern Italy presented the lowest levels of education and the highest rate of unemployment compared to other groups. Females, pts aged &gt; 50 yrs., unemployed vs employed, and people with lower educational levels presented the lowest CD4 count at ART initiation compared to other groups. The overall median time to ART initiation was 0.6 years (yrs) (IQR 0.1-3.7), with a significant decrease over time [2002-2006 = 3.3 yrs. (0.2-9.4); 2007-2011 = 1.0 yrs. (0.1-3.9); 2012-2016 = 0.2 yrs. (0.1-2.1), p &lt; 0.001]. By multivariate analysis, females (p &lt; 0.01) and PWID (p &lt; 0.001), presented a longer time to ART initiation, while older people (p &lt; 0.001), people with higher educational levels (p &lt; 0.001), unemployed (p = 0.02) and students (p &lt; 0.001) were more likely to initiate ART. Moreover, PWID, unemployed vs stable employed, and pts. with lower educational levels showed a lower 1-year probability of achieving HIV-RNA suppression, while females, older patients, men who have sex with men (MSM), unemployed had higher 1-year risk of first-line ART discontinuation. Conclusions: Despite median time to ART start decreased from 2002 to 2016, socio-demographic factors still contribute to disparities in ART initiation, outcome and durability