On the correction of anomalous phase oscillation in entanglement witnesses using quantum neural networks

Entanglement of a quantum system depends upon relative phase in complicated ways, which no single measurement can reflect. Because of this, entanglement witnesses are necessarily limited in applicability and/or utility. We propose here a solution to the problem using quantum neural networks. A quantum system contains the information of its entanglement; thus, if we are clever, we can extract that information efficiently. As proof of concept, we show how this can be done for the case of pure states of a two-qubit system, using an entanglement indicator corrected for the anomalous phase oscillation. Both the entanglement indicator and the phase correction are calculated by the quantum system itself acting as a neural network

Electrical activity of carbon-hydrogen centers in Si

The electrical activity of Cs-H defects in Si has been investigated in a combined modeling and experimental study. High-resolution Laplace capacitance spectroscopy with the uniaxial stress technique has been used to measure the stress-energy tensor and the results are compared with theoretical modeling. At low temperatures, implanted H is trapped as a negative-U center with a donor level in the upper half of the gap. However, at higher temperatures, H migrates closer to the carbon impurity and the donor level falls, crossing the gap. At the same time, an acceptor level is introduced into the upper gap making the defect a positive-U center

Analisis Biaya Diferensial dalam Pengambilan Keputusan Memproduksi Sendiri Atau Membeli Bahan Baku pada Rm. Bakso Ba Nyuk Nyang Manado

Perkembangan ilmu pengetahuan dan teknologi berdampak pada persaingan dunia usaha yang semakin ketat, baik Perusahaan yang bergerak di bidang industri, perdagangan maupun jasa. Berhasil tidaknya Perusahaan dalam mencapai tujuannya tergantung pada manajemen Perusahaan tersebut, apakah manajemen suatu Perusahaan sudah mampu mencapai tujuan Perusahaan sebenarnya, baik itu jangka pendek maupun jangka panjang. Sehingga dalam menjalankan kegiatan suatu Perusahaan, maka seringkali manajemen dihadapkan pada beberapa pilihan atau alternatif dari aktivitas yang dilakukan. Analisis biaya diferensial sangat diperlukan sesuai dengan masalah yang dihadapi oleh Perusahaan dalam usaha meningkatkan laba dan mengurangi kerugian. Biaya diferensial didefinisikan sebagai perbedaan biaya yang timbul akibat adanya keputusan tertentu. Tujuan penelitian ini untuk menganalisis biaya diferensial dalam pengambilan keputusan memproduksi sendiri atau membeli bahan baku pada RM. Bakso Ba Nyuk-Nyang Manado. Metode analisis yang digunakan adalah metode deskriptif kuantitatif. Hasil penelitian dilihat dari biaya diferensial menunjukan biaya yang akan dikeluarkan lebih kecil apabila pihak manajemen memproduksi sendiri dari pada membeli dari pemasok. Sebaiknya pimpinan RM. Bakso Ba Nyuk-Nyang, memproduksi mie sendiri karena lebih menguntungkan dan juga dapat menghemat biaya. Kata kunci: biaya diferensial, produksi bahan bak

Procedures for the salvage and necropsy of the dugong (dugong dugon)

This manual provides a detailed guide for dugong (Dugong dugon) carcass handling and necropsy procedures. It is intended to be used as a resource and training guide for anyone involved in dugong incidents, including management officers, biologists, parks and wildlife field staff, and veterinarians and pathologists who may lack dugong expertise. Because of the wide range of professionals this book is targeting, information and the use of technical terms is necessarily extensive. Section 8 provides definitions of various terms used and italicised throughout the text

Molecular docking studies of different phytochemicals obtained from medicinal Plants of Uttarakhand region for identification of potential inhibitors against mucormycosis causing fungal species

Mucormycosis is an insidious fungal infection caused by members of Mucorales and zygomycotic species. During the last few years, mucormycosis has become the third most common invasive fungal infection in patients with haematological malignancies and organ transplantations. The incidence of mucormycosis is particularly high in patients with immunocompromised health. It has been reported that CotH receptor proteins have a potential role in binding  Rhizopus species with the host cells. Further, CotH1, CotH2, and CotH3 are the spore-coating protein of mucormycosis, which are mostly responsible for the invasion of host cells and causing diseases. The present study aimed to predict the structure of CotH1, CotH2, and CotH3 receptors in Rhizpous delemar using homology modelling on SWISS Server and validated the model based on GMQE and QMEAN scores followed by analysis of the predicted model on Ramachandran plot. Further, molecular docking studies of the predominant 46 phytochemicals found in the medicinal plants of Uttarakhand region, India were done against these three receptors. Autodock vina results have shown that the binding energy value of Curcumin was -8.5 Kcal/mol against CotH1, and the binding energy value of Allosecurinin was  -7.6 Kcal/mol against CotH2 and binding energy value of Isoquercetin was -7.7 Kcal/mol against CotH3. Evaluation of the ADMET parameters has shown the high efficacy of these compounds. The present Insilico study suggests that Curcumin, Allosecurinine, and Isoquercetin are effective lead molecules against the receptors CotH1, CotH2, and CotH3 in the mucormycosis caused by fungal species R. delemar

The Genetic Requirements for Fast and Slow Growth in Mycobacteria

Mycobacterium tuberculosis infects a third of the world's population. Primary tuberculosis involving active fast bacterial replication is often followed by asymptomatic latent tuberculosis, which is characterised by slow or non-replicating bacteria. Reactivation of the latent infection involving a switch back to active bacterial replication can lead to post-primary transmissible tuberculosis. Mycobacterial mechanisms involved in slow growth or switching growth rate provide rational targets for the development of new drugs against persistent mycobacterial infection. Using chemostat culture to control growth rate, we screened a transposon mutant library by Transposon site hybridization (TraSH) selection to define the genetic requirements for slow and fast growth of Mycobacterium bovis (BCG) and for the requirements of switching growth rate. We identified 84 genes that are exclusively required for slow growth (69 hours doubling time) and 256 genes required for switching from slow to fast growth. To validate these findings we performed experiments using individual M. tuberculosis and M. bovis BCG knock out mutants. We have demonstrated that growth rate control is a carefully orchestrated process which requires a distinct set of genes encoding several virulence determinants, gene regulators, and metabolic enzymes. The mce1 locus appears to be a component of the switch to slow growth rate, which is consistent with the proposed role in virulence of M. tuberculosis. These results suggest novel perspectives for unravelling the mechanisms involved in the switch between acute and persistent TB infections and provide a means to study aspects of this important phenomenon in vitro

Procedures for the salvage and necropsy of the Dugong (Dugong Dugon)-second edition 2007

This manual provides a detailed guide for dugong (Dugong dugon) carcass handling and necropsy procedures. It is intended to be used as a resource and training guide for anyone involved in dugong incidents including management officers, biologists, parks and wildlife field staff, and veterinarians and pathologists who may lack dugong expertise. Because of the wide range of professionals this book is targeting, information and the use of technical terms is extensive. Section 8.0 provides definitions of various terms used which are italicised throughout the text

Bio-Guided Fractionation and Molecular Networking Reveal Fatty Acids to Be Principal Anti-Parasitic Compounds in Nordic Seaweeds

Copyright © 2021 Bonde, Bornancin, Lu, Simonsen, Martínez-Valladares, Peña- Espinoza, Mejer, Williams and Thamsborg. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.[EN]Widespread use of antimicrobial drugs has led to high levels of drug-resistance in pathogen populations and a need for novel sources of anti-bacterial and anti-parasitic compounds. Macroalgae (seaweed) are potentially a rich source of bioactive compounds, and several species have traditionally been used as vermifuges. Here, we investigated the anti-parasitic properties of four common cold-water Nordic seaweeds; Palmaria palmata (Rhodophyta), Laminaria digitata, Saccharina latissima and Ascophyllum nodosum (Ochrophyta, Phaeophyceae). Screening of organic extracts against helminths of swine (Ascaris suum) and sheep (Teladorsagia circumcincta) revealed that S. latissima and L. digitata had particularly high biological activity. A combination of molecular networking and bio-guided fractionation led to the isolation of six compounds from extracts of these two species identified in both fermented and non-fermented samples. The six isolated compounds were tentatively identified by using MS-FINDER as five fatty acids and one monoglyceride: Stearidonic acid (1), Eicosapentaenoic acid (2), Alpha-Linolenic acid (3), Docosahexaenoic acid (4), Arachidonic acid (5), and Monoacylglycerol (MG 20:5) (6). Individual compounds showed only modest activity against A. suum, but a clear synergistic effect was apparent when selected compounds were tested in combination. Collectively, our data reveal that fatty acids may have a previously unappreciated role as natural anti-parasitic compounds, which suggests that seaweed products may represent a viable option for control of intestinal helminth infections.SIThis project was funded by the Green Development and Demonstration Program (GUDP) (Project No. 34009–17–1220). In vitro studies performed on T. circumcincta was funded by Short Term Scientific Mission (STSM) Grant provided by European Cooperation in Science and Technology (COST CA16230 - Combatting anthelmintic resistance in ruminants). MM-V funded by the Spanish “Ramon y Cajal” Program (Ministerio de Economía y Competitividad; MM-V, RYC-2015–18368)