375 research outputs found
Star cluster survival and compressive tides in Antennae-like mergers
Gravitational tides are widely understood to strip and destroy galactic
substructures. In the course of a galaxy merger, however, transient totally
compressive tides may develop and prevent star forming regions from dissolving,
after they condensed to form clusters of stars. We study the statistics of such
compressive modes in an N-body model of the galaxy merger NGC 4038/39 (the
Antennae) and show that ~15% of the disc material undergoes compressive tides
at pericentre. The spatial distribution of observed young clusters in the
overlap and nuclear regions of the Antennae matches surprisingly well the
location of compressive tides obtained from simulation data. Furthermore, the
statistics of time intervals spent by individual particles embedded in a
compressive tide yields a log-normal distribution of characteristic time ~10
Myr, comparable to star cluster formation timescales. We argue that this
generic process is operative in galaxy mergers at all redshifts and possibly
enhances the formation of star clusters. We show with a model calculation that
this process will prevent the dissolution of a star cluster during the
formation phase, even for a star formation efficiency as low as ~10%. The
transient nature of compressive tides implies that clusters may dissolve
rapidly once the tidal field switches to the usual disruptive mode.Comment: 5 pages, 3 figures, accepted for publication in MNRAS Letters. For
higher resolution, see http://astro.u-strasbg.fr/~renaud/publi/mnras08.pd
The role of heterosexual anal intercourse for HIV transmission in developing countries: are we ready to draw conclusions?
Energy ejection in the collapse of a cold spherical self-gravitating cloud
When an open system of classical point particles interacting by Newtonian
gravity collapses and relaxes violently, an arbitrary amount of energy may in
principle be carried away by particles which escape to infinity. We investigate
here, using numerical simulations, how this released energy and other related
quantities (notably the binding energy and size of the virialized structure)
depends on the initial conditions, for the one parameter family of starting
configurations given by randomly distributing N cold particles in a spherical
volume. Previous studies have established that the minimal size reached by the
system scales approximately as N^{-1/3}, a behaviour which follows trivially
when the growth of perturbations (which regularize the singularity of the cold
collapse in the infinite N limit) are assumed to be unaffected by the
boundaries. Our study shows that the energy ejected grows approximately in
proportion to N^{1/3}, while the fraction of the initial mass ejected grows
only very slowly with N, approximately logarithmically, in the range of N
simulated. We examine in detail the mechanism of this mass and energy ejection,
showing explicitly that it arises from the interplay of the growth of
perturbations with the finite size of the system. A net lag of particles
compared to their uniform spherical collapse trajectories develops first at the
boundaries and then propagates into the volume during the collapse. Particles
in the outer shells are then ejected as they scatter through the time dependent
potential of an already re-expanding central core. Using modified initial
configurations we explore the importance of fluctuations at different scales,
and discreteness (i.e. non-Vlasov) effects in the dynamics.Comment: 20 pages, 27 figures; revised version with small changes and
corrections, to appear in MNRA
The mass-to-light ratio of rich star clusters
We point out a strong time-evolution of the mass-to-light conversion factor
eta commonly used to estimate masses of unresolved star clusters from observed
cluster spectro-photometric measures. We present a series of gas-dynamical
models coupled with the Cambridge stellar evolution tracks to compute
line-of-sight velocity dispersions and half-light radii weighted by the
luminosity. We explore a range of initial conditions, varying in turn the
cluster mass and/or density, and the stellar population's IMF. We find that
eta, and hence the estimated cluster mass, may increase by factors as large as
3 over time-scales of 50 million years. We apply these results to an hypothetic
cluster mass distribution function (d.f.) and show that the d.f. shape may be
strongly affected at the low-mass end by this effect. Fitting truncated
isothermal (Michie-King) models to the projected light profile leads to
over-estimates of the concentration parameter c of delta c ~ 0.3 compared to
the same functional fit applied to the projected mass density.Comment: 6 pages, 2 figures, to appear in the proceedings of the "Young
massive star clusters", Granada, Spain, September 200
Effects of the integrated galactic IMF on the chemical evolution of the solar neighbourhood
The initial mass function determines the fraction of stars of different
intial mass born per stellar generation. In this paper, we test the effects of
the integrated galactic initial mass function (IGIMF) on the chemical evolution
of the solar neighbourhood. The IGIMF (Weidner & Kroupa 2005) is computed from
the combination of the stellar intial mass function (IMF), i.e. the mass
function of single star clusters, and the embedded cluster mass function, i.e.
a power law with index beta. By taking into account also the fact that the
maximum achievable stellar mass is a function of the total mass of the cluster,
the IGIMF becomes a time-varying IMF which depends on the star formation rate.
We applied this formalism to a chemical evolution model for the solar
neighbourhood and compared the results obtained by assuming three possible
values for beta with the results obtained by means of a standard, well-tested,
constant IMF. In general, a lower absolute value of beta implies a flatter
IGIMF, hence a larger number of massive stars and larger metal ejection rates.
This translates into higher type Ia and II supernova rates, higher mass
ejection rates from massive stars and a larger amount of gas available for star
formation, coupled with lower present-day stellar mass densities. (abridged) We
also discuss the importance of the present day stellar mass function (PDMF) in
providing a way to disentangle among various assumptions for beta. Our results
indicate that the model adopting the IGIMF computed with beta ~2 should be
considered the best since it allows us to reproduce the observed PDMF and to
account for most of the chemical evolution constraints considered in this work.Comment: 22 pages, 19 figure
Potential population-level effectiveness of one-dose HPV vaccination in low-income and middle-income countries: a mathematical modelling analysis
BACKGROUND: Given the accumulating evidence that one-dose vaccination could provide high and sustained protection against human papillomavirus (HPV) infection and related diseases, we examined the population-level effectiveness and efficiency of one-dose HPV vaccination of girls compared with two-dose vaccination, using mathematical modelling. METHODS: In this mathematical modelling study, we used HPV-ADVISE LMIC, an individual-based transmission-dynamic model independently calibrated to four epidemiologically diverse low-income and middle-income countries (LMICs; India, Nigeria, Uganda, and Viet Nam). We parameterised and calibrated the model using sexual behaviour and epidemiological data identified from international population-based datasets and the literature. All base-case vaccination scenarios start in 2023 with the nonavalent vaccine and assumed 80% vaccination coverage with one or two doses. We assumed that two doses of vaccine provide 100% efficacy against vaccine-type infections and a lifelong duration of protection. We examined a non-inferior vaccination scenario for one dose compared with two doses, pessimistic scenarios of lower one-dose vaccine efficacy (85%) or a shorter duration of protection (ie, 20 or 30 years), and the effectiveness of a mitigation scenario in which schedules would switch from one dose to two doses. We also did sensitivity analyses by varying vaccination coverage. We used three outcomes: the relative reduction in cervical cancer incidence, the number of cervical cancers averted, and the number of vaccine doses needed to prevent one cervical cancer. FINDINGS: Assuming non-inferior vaccine characteristics for one dose compared with two doses, the model projections show that two-dose or one-dose routine vaccination of girls aged 9 years (with a multi-age cohort vaccination of girls aged 10-14 years) would avert 12·0 million (80% UI 9·5-14·5) cervical cancers in India, 4·7 million (3·4-5·8) in Nigeria, 2·3 million (1·9-2·6) in Uganda, and 0·4 million (0·2-0·5) in Viet Nam over 100 years. Under pessimistic assumptions of lower one-dose efficacy (85%) or a shorter duration of protection (ie, 30 years), one-dose routine vaccination would avert 69% (61-80) to 94% (92-96) of the cervical cancers averted with two-dose routine vaccination. However, when assuming a duration of protection of 20 years, one-dose routine vaccination would avert substantially fewer cervical cancers (ie, 35% [26-44] to 69% [65-71] of the cervical cancers averted with two-dose routine vaccination). A switch from one-dose to two-dose routine vaccination of girls aged 9 years, with a one-dose catch-up of girls aged 10-14 years, 5 years after the start of the vaccination programme, could mitigate potential losses in cervical cancer prevention from a short one-dose duration of protection (averting 92% [83-98] to 99% [97-100]) of the cervical cancers averted with two-dose routine vaccination). One-dose routine vaccination would result in fewer doses needed to prevent one cervical cancer than two-dose routine vaccination, even if the duration of protection is as low as 20 years. Finally, for countries with two-dose routine vaccination, adding one-dose multi-age cohort vaccination in the first year would provide similar benefits as a two-dose multi-age cohort vaccination, and would be more efficient even under the pessimistic assumptions of lower one-dose vaccine efficacy or duration of protection. INTERPRETATION: One-dose routine vaccination could avert most of the cervical cancers averted with two-dose vaccination while being more efficient, provided the duration of one-dose protection is greater than 20-30 years (depending on the LMIC). The doses saved by introducing one-dose routine vaccination could offer the opportunity to vaccinate girls before they age out of the vaccination window of 9-14 years and, potentially, to vaccinate boys or older age groups. FUNDING: Fonds de recherche du Québec-Santé, Digital Research Alliance of Canada, Bill & Melinda Gates Foundation
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