2,656 research outputs found
Negative ion spectrometry for detecting nitrated explosives
Ionization procedure is modified to produce mainly negative ions by electron capture. Peaks of negative ions are monitored conventionally. Nitrated organic materials could be identified directly from sample sniff inlet stream by suitably modified mass spectrometer because of unique electronegativity which nitro group imparts to organic material
Electronic Stopping and Momentum Density of Diamond Obtained from First-Principles Calculations
We calculate the "head" element or the (0,0)-element of the wave-vector and
frequency-dependent dielectric matrix of bulk crystals via first-principles,
all-electron Kohn-Sham states in the integral of the irreducible polarizability
in the random phase approximation. We approximate the macroscopic "head"
element of the inverse matrix by its reciprocal value, and integrate over
frequencies and momenta to obtain the electronic energy loss of protons at low
velocities. Numerical evaluation for diamond targets predicts that the band gap
causes a strong non-linear reduction of the electronic stopping power at ion
velocities below 0.2 atomic units.Comment: 8 pages, 6 figures, REVTeX
Tuberculosis vaccine strain _Mycobacterium bovis_ BCG Russia is a natural _recA_ mutant
The current tuberculosis vaccine is a live vaccine derived from _Mycobacterium bovis_ and attenuated by serial _in vitro_ passaging. All vaccine substrains in use stem from one source, strain Bacille Calmette-Guérin. However, they differ in regions of genomic deletions, antigen expression levels, immunogenicity, and protective efficacy. As a RecA phenotype increases genetic stability and may contribute restricting the ongoing evolution of the various BCG substrains, we aimed to inactivate _recA_ by allelic replacement in BCG vaccine strains representing different phylogenetic lineages (Pasteur, Frappier, Denmark, Russia). Homologous gene replacement was successful in three out of four strains. However, only illegitimate recombination was observed in BCG substrain Russia. Sequence analyses of _recA_ revealed that a single nucleotide insertion in the 5' part of _recA_ led to a translational frameshift with an early stop codon making BCG Russia a natural _recA_ mutant. At the protein level BCG Russia failed to express RecA. According to phylogenetic analyses BCG Russia is an ancient vaccine strain most closely related to the parental _M. bovis_. Our data suggest that _recA_ inactivation in BCG Russia occurred early and is in part responsible for its high degree of genomic stability, resulting in a substrain that has less genetic alterations than other vaccine substrains with respect to _M. bovis_ AF2122/97 wild type
High-pressure Debye-Waller and Grueneisen parameters of Au and Cu
The lattice vibrations are determined in the quasi-harmonic approximation for
elemental Au and Cu to twice their normal density by first-principles
electronic band-structure calculations. It is found for these materials that
the important moments of the phonon density of states can be obtained to high
accuracy from short-ranged force constant models. We discuss the implications
for the Grueneisen parameters on the basis of calculated phonon moments and
their approximations by using bulk moduli and Debye-Waller factors.Comment: 4 pages, 2 figures to appear in the proceedings of the 13th APS
Topical Conference on Shock Compression of Condensed Matter (scheduled for
April 2004
Virtual machine scheduling in dedicated computing clusters
Time-critical applications process a continuous stream of input data and have to meet specific timing constraints. A common approach to ensure that such an application satisfies its constraints is over-provisioning: The application is deployed in a dedicated cluster environment with enough processing power to achieve the target performance for every specified data input rate. This approach comes with a drawback: At times of decreased data input rates, the cluster resources are not fully utilized. A typical use case is the HLT-Chain application that processes physics data at runtime of the ALICE experiment at CERN. From a perspective of cost and efficiency it is desirable to exploit temporarily unused cluster resources. Existing approaches aim for that goal by running additional applications. These approaches, however, a) lack in flexibility to dynamically grant the time-critical application the resources it needs, b) are insufficient for isolating the time-critical application from harmful side-effects introduced by additional applications or c) are not general because application-specific interfaces are used. In this thesis, a software framework is presented that allows to exploit unused resources in a dedicated cluster without harming a time-critical application. Additional applications are hosted in Virtual Machines (VMs) and unused cluster resources are allocated to these VMs at runtime. In order to avoid resource bottlenecks, the resource usage of VMs is dynamically modified according to the needs of the time-critical application. For this purpose, a number of previously not combined methods is used. On a global level, appropriate VM manipulations like hot migration, suspend/resume and start/stop are determined by an informed search heuristic and applied at runtime. Locally on cluster nodes, a feedback-controlled adaption of VM resource usage is carried out in a decentralized manner. The employment of this framework allows to increase a cluster’s usage by running additional applications, while at the same time preventing negative impact towards a time-critical application. This capability of the framework is shown for the HLT-Chain application: In an empirical evaluation the cluster CPU usage is increased from 49% to 79%, additional results are computed and no negative effect towards the HLT-Chain application are observed
Virtual machine scheduling in dedicated computing clusters
Time-critical applications process a continuous stream of input data and have to meet specific timing constraints. A common approach to ensure that such an application satisfies its constraints is over-provisioning: The application is deployed in a dedicated cluster environment with enough processing power to achieve the target performance for every specified data input rate. This approach comes with a drawback: At times of decreased data input rates, the cluster resources are not fully utilized. A typical use case is the HLT-Chain application that processes physics data at runtime of the ALICE experiment at CERN. From a perspective of cost and efficiency it is desirable to exploit temporarily unused cluster resources. Existing approaches aim for that goal by running additional applications. These approaches, however, a) lack in flexibility to dynamically grant the time-critical application the resources it needs, b) are insufficient for isolating the time-critical application from harmful side-effects introduced by additional applications or c) are not general because application-specific interfaces are used. In this thesis, a software framework is presented that allows to exploit unused resources in a dedicated cluster without harming a time-critical application. Additional applications are hosted in Virtual Machines (VMs) and unused cluster resources are allocated to these VMs at runtime. In order to avoid resource bottlenecks, the resource usage of VMs is dynamically modified according to the needs of the time-critical application. For this purpose, a number of previously not combined methods is used. On a global level, appropriate VM manipulations like hot migration, suspend/resume and start/stop are determined by an informed search heuristic and applied at runtime. Locally on cluster nodes, a feedback-controlled adaption of VM resource usage is carried out in a decentralized manner. The employment of this framework allows to increase a cluster’s usage by running additional applications, while at the same time preventing negative impact towards a time-critical application. This capability of the framework is shown for the HLT-Chain application: In an empirical evaluation the cluster CPU usage is increased from 49% to 79%, additional results are computed and no negative effect towards the HLT-Chain application are observed
A Study of the Vocabulary Growth Made by Intermediate Students with Learning Disabilities When Exposed to Repeated Readings
For years researchers and educators alike have been looking for successful methods of phonics instruction for students with disabilities. All too often, students with learning disabilities struggle with word attack and focus on the method in isolation, often omitting the other mutually important aspects of reading such as fluency and comprehension. In addition, students with disabilities have not been successful at sounding out multi-syllabic words as a result of their phonetic usage deficits. The purpose of this study was to determine if the method of repeated readings helps students with learning disabilities to develop secondary phonological awareness skills and thus, higher level vocabulary.
Students with learning disabilities read short take-home books with the researcher aloud at least twice per week. When a criterion rate of at least 85 words per minute and no more than five errors was achieved, a new book was started. Students kept track of their progress for each book on a chart posted in the classroom.
After five months, students were given the Word Identification Subtest of the Woodcock Reading Mastery Test-Revised. These results were compared with a control group of students with learning disabilities who did not receive instruction in the method of repeated readings. The results showed that there was no statistically significant difference between vocabulary development for the group that participated in the repeated readings method and the group who received no repeated readings practice
Sample processor for chemical analysis
An apparatus is provided which can process numerous samples that must be chemically analyzed by the application of fluids such as liquid reagents, solvents and purge gases, as well as the application of dumps for receiving the applied fluid after they pass across the sample, in a manner that permits numerous samples to be processed in a relatively short time and with minimal manpower. The processor includes a rotor which can hold numerous cartridges containing inert or adsorbent material for holding samples, and a pair of stators on opposite sides of the rotor. The stators form stations spaced along the path of the cartridges which lie in the rotor, and each station can include an aperture in one stator through which a fluid can be applied to a cartridge resting at that station, and an aperture in the other stator which can receive the fluid which has passed through the cartridge. The stators are sealed to the ends of the cartridges lying on the rotor, to thereby isolate the stations from one another
Automated mass spectrometer/analysis system: A concept
System performs rapid multiple analyses of entire compound classes or individual compounds on small amounts of sample and reagent. Method will allow screening of large populations for metabolic disorders and establishment of effective-but-safe levels of therapeutic drugs in body fluids and tissues
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