327 research outputs found

    Theatre as transformative practice : a heuristic exploration of the psychosomatic dynamics of self-expressive theatre practices

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    An exploration into the psychosomatic dynamics of theatre-based practices was undertaken using heuristic methodology (Moustakas, 1990). Twenty-two practitioners, some working independently, others working collaboratively, were interviewed about their approaches, focusing on their experiences of self-expressive performance as a way to work on the self and to induce healing and/or transformative growth. The heuristic approach also allowed for the researcher's direct involvement and participation in the practices under investigation, enabling her to explore firsthand the potential of theatre-based practice as a means to work on the self. Following heuristic methodology, the researcher created a Composite Depiction and a Creative Synthesis, juxtaposing the individual approaches of the research participants and highlighting the core elements of Theatre as a Transformative Practice. In doing so, she proposed that the practices explored facilitate an attunement of ego, some leading to deep, body-based introspection which in turn enables the practitioner to gain greater self-insight and internal balance through expressive engagement with felt senses and corresponding imagery. The researcher further suggested that Theatre as a Transformative Practice requires specific conditions under which the creative journey can lead to healing and personal growth. The chief condition identified was that the work be approached with mindful awareness of others and self in the performative relationship

    The Global Impact of COVID-19 and Tourism on Conservation Rangers\u27 Guardianship Capabilities

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    This thesis explores how the COVID-19 pandemic has impacted wildlife rangers with an emphasis on the influences of tourism rates. Two sets of data are used: one is a survey of rangers around the world and the other looks at global governmental tourism data. While coming from a routine activities perspective, the problem of decreased capable guardianship becomes apparent in the form of massively decreased tourism arrivals and troubling ranger perceptions. This data allows for the establishment of tourism trends and changes during COVID. The findings of this thesis link the downturn in tourism with impacts on formal and informal guardianship within protected areas. Recommendations and discussions include potential ways to preserve guardianship in future pandemic settings

    Lectura a fondo 2

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    Contiene artículos de Carlos Guzman Bockler... [et al.]¿Exclusiones renovadas? tierra y migración en el siglo XXI. Visiones perifericas: poder y cotidianidad en las orillas de la Republica. Guatemala: Memoria abierta: el conflicto armado en perspectiva 1954-199

    Endovascular stenting of a chronic ruptured type B thoracic aortic dissection, a second chance: a case report

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    <p>Abstract</p> <p>Introduction</p> <p>We aim to highlight the need for awareness of late complications of endovascular thoracic aortic stenting and the need for close follow-up of patients treated by this method.</p> <p>Case presentation</p> <p>We report the first case in the English literature of an endovascular repair of a previously stented, ruptured chronic Stanford type B thoracic aortic dissection re-presenting with a type III endoleak of the original repair.</p> <p>Conclusion</p> <p>Endovascular thoracic stenting is now a widely accepted technique for the treatment of thoracic aortic dissection and its complications. Long term follow up is necessary to ensure that late complications are identified and treated appropriately. In this case of type III endoleak, although technically challenging, endovascular repair was feasible and effective.</p

    Domain-oriented edge-based alignment of protein interaction networks

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    Motivation: Recent advances in high-throughput experimental techniques have yielded a large amount of data on protein–protein interactions (PPIs). Since these interactions can be organized into networks, and since separate PPI networks can be constructed for different species, a natural research direction is the comparative analysis of such networks across species in order to detect conserved functional modules. This is the task of network alignment

    DIMA 3.0: Domain Interaction Map

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    Domain Interaction MAp (DIMA, available at http://webclu.bio.wzw.tum.de/dima) is a database of predicted and known interactions between protein domains. It integrates 5807 structurally known interactions imported from the iPfam and 3did databases and 46 900 domain interactions predicted by four computational methods: domain phylogenetic profiling, domain pair exclusion algorithm correlated mutations and domain interaction prediction in a discriminative way. Additionally predictions are filtered to exclude those domain pairs that are reported as non-interacting by the Negatome database. The DIMA Web site allows to calculate domain interaction networks either for a domain of interest or for entire organisms, and to explore them interactively using the Flash-based Cytoscape Web software

    Incidence, natural course, and outcome of type II endoleaks in infrarenal endovascular aneurysm repair based on the ENGAGE registry data

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    Objective: The purpose of this study was to report the incidence, natural history, and outcome of type II endoleaks in the largest prospective real-world cohort to date. Methods: Patients were extracted from the prospective Endurant Stent Graft Natural Selection Global Postmarket Registry (ENGAGE). Two groups were analyzed: first, patients with an isolated type II endoleak; and second, patients with a type II endoleak who later presented with a type I endoleak. A health status analysis between patients with an early type II endoleak and patients with no endoleak was performed. Second, an attempt was made to identify risk factors in patients with a type II endoleak who later presented with a type I endoleak. Results: Through 5 years of follow-up, a total of 197 (15.6%) patients with isolated type II endoleaks were identified. Most were detected within the first 30 days (n = 73 [37.1%]) and through the first year (n = 73 [37.1%]), with the remainder being detected after 1 year of follow-up (n = 51 [25.8%]). Patients with a type II endoleak had a higher incidence of aneurysm growth and more secondary endovascular procedures (15.4% vs 7.5% at 5 years; P <.001). Overall survival was higher in the isolated type II endoleak group compared with patients with no endoleak (77.2% vs 67.0% at 5 years; P =.010). Twenty-two patients (10%) with a type II endoleak were diagnosed with a late type I endoleak (type IA, n = 10; type IB, n = 12), with a secondary intervention rate of 67.5% through 5 years. There was no difference in health status scores between patients with an early type II endoleak and patients without any type of endoleak at 1-year follow-up. Conclusions: In the ENGAGE registry, isolated type II endoleaks are present in 15.6% of patients during follow-up. The majority do not require secondary intervention, and an early isolated type II endoleak does not have an impact on health status through 1 year. However, a small group of patients with a type II endoleak will present with a type I endoleak, resulting in a high secondary intervention rate and significant risk of aneurysm-related complications

    Zygomycetes, Microsporidia, and the Evolutionary Ancestry of Sex Determination

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    Zygomycetes and their alleged sister taxon, the microsporidia, exclusively share the presence of a cluster of three genes encoding a sugar transporter, a high mobility group (HMG)-type transcription factor, and an RNA helicase. In zygomycetes, the HMG-type transcription factor acts as the sole sex determinant. This intimately ties the evolutionary history of this gene cluster to the evolution of sex determination. Here, we have unraveled the relationships of the two gene clusters by vicariously analyzing the sugar transporters and the RNA helicases. We show that if the two gene clusters share a common ancestry, it dates back to the early days of eukaryotic evolution. As a consequence, the zygomycete MAT locus would be old enough to represent the archetype of fungal and animal sex determination. However, the evolutionary scenario that has to be invoked is complex. An independent assembly of the two clusters deserves therefore consideration. In either case, shared ancestry or convergent evolution, the presence of the gene cluster in microsporidia and in zygomycetes represents at best a plesiomorphy. Hence, it is not phylogenetically informative. A further genome-wide reanalysis of gene order conservation reveals that gene order is not significantly more similar between microsporidia and zygomycetes than between microsporidia and any other fungal taxon or even humans. Consequently, the phylogenetic placement of microsporidia as sister to the zygomycetes needs to be reconsidered
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