349 research outputs found

    Percorsi di Educazione in Natura: ri-orientare l’umano verso uno sviluppo sostenibile

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    La situazione attuale ci presenta la necessità di un ri-orientamento dell’educazione verso uno sviluppo sostenibile, consapevole e non retorico. Nel contributo verranno analizzati alcuni modelli e pratiche di educazione ambientale che mirano a superare sporadiche esperienze nel verde per creare una nuova consapevolezza ambientale dove è necessaria una forte condivisione di una prospettiva comune che promuova un nuovo ruolo dell’uomo con e nella Natura. Perché questo si realizzi è prioritaria l’acquisizione di un habitus mentale e comportamentale continuativo, profondo e critico (UNESCO, 2021, p. 11) che non sia solo una speculazione ecologica teorica o occasionale. In particolare, verrà presentato il progetto SentieriOutdoor che apre alla possibilità di riconnetterci con l’ambiente attraverso un tempo a misura di persona e ci permette di ritrovare la complessità della nostra umanità nella relazione con la Natura

    School Climate: Parents\u2019, Students\u2019 And Teachers\u2019 Perceptions

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    Because of the importance of individual perceptions, schools often assess how students or teachers or parents feel about their school, and school climate has often been associated with improved school achievement, but rarely they take into account all these \u201cactors\u201d at the same time. The main aim of this work is to compare the results obtained in a population study on school climate that involves students, parents, teachers and non-teaching staff. In this paper, we will present the results of parents\u2019, students\u2019, teachers\u2019 and no-teacher personnel's perception. We have administered 13,500 structured questionnaires addressed to students, parents, teachers, educational assistance personnel, involved in the four orders of schools (Pre-school, Elementary, Middle, High) of the province of Bolzano. Parental permission was obtained for young people. The present study has been conducted in the province of Bolzano, northern Italy, between January and April 2012. A School Climate Perception Questionnaire (SCPQ), that can be completed in 10 minutes, has been developed to assess environments and climate of all Italian language schools. In order to determine the interrelationships among the questionnaire items, a Principal-Axis Factor Analysis was performed. The final scale was used for Confirmatory Factor Analysis that was done to assess its construct validity. We will present the results regarding the school climate perceptions of teachers, parents and students and their comparison

    Anabolic effects and inhibition of interleukin 6 production induced by neridronate on human osteoblasts

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    Bisphosphonates (BPs) are pharmacological compounds widely used in the treatment of a variety of bone-related diseases, particularly where the bone-turnover is skewed in favour of osteolysis. The mechanisms by which BPs reduce bone-resorption directly acting on osteoclasts (OCs) are now largely clarified even at molecular level. The researches concerning the BPs effects on osteoblasts (OBs) have instead shown variable results. Objectives: We have investigated the efficacy of neridronate (NER), an amino-BP, as anabolic agent on human OBs. Moreover, we have tried to verify if NER is able to negatively modulate the production of IL-6 on OBs stimulated or not by the pro-inflammatory cytokine Il-1b. Methods: We have tested if different concentrations of NER (from 10-11M to 10-3M), added to primary human OB cultures, could affect the cells number, the endogenous cellular alkaline phosphatase (ALP) activity, the collagen I (COLI) synthesis, the formation of mineralized nodules and the IL-6 production. Our experimental approach was performed testing a wide range of NER concentrations because, under physiological conditions, OBs seems to be exposed to variable and transient levels of the drug. Results: Our results show that NER doesn't negatively affect in vitro the viability, proliferation and cellular activity of human OBs, even after 20 days of exposure to concentrations ²10-5 M (therapeutic dose). In addition, NER seems to enhance the differentiation of cultured OBs in mature bone-forming cells. A maximum increase of COL-I synthesis (+25% after 4 days; p<0.05), ALP activity (+50% after 10 days; p<0.01) and mineralized nodules (+48% after 20 days; p<0.05) was observed in cultures treated with NER 10-8M. A maximal reduction of IL-6 secretion (-24% on IL-1b stimulated cultures and -29% on unstimulated cultures) was observed for NER 10-9 M. Conclusions: These results encourage the use of neridronate in therapy of demineralizing metabolic bone disorders

    Explicit connection actions in multiparty session types

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    This work extends asynchronous multiparty session types (MPST) with explicit connection actions to support protocols with op- tional and dynamic participants. The actions by which endpoints are connected and disconnected are a key element of real-world protocols that is not treated in existing MPST works. In addition, the use cases motivating explicit connections often require a more relaxed form of mul- tiparty choice: these extensions do not satisfy the conservative restric- tions used to ensure safety in standard syntactic MPST. Instead, we de- velop a modelling-based approach to validate MPST safety and progress for these enriched protocols. We present a toolchain implementation, for distributed programming based on our extended MPST in Java, and a core formalism, demonstrating the soundness of our approach. We discuss key implementation issues related to the proposed extensions: a practi- cal treatment of choice subtyping for MPST progress, and multiparty correlation of dynamic binary connections

    Controlled growth of InAs nanowires on engineered substrates

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    We demonstrate the Au-assisted growth of semiconductor nanowires on different engineered substrates. Two relevant cases are investigated: GaAs/AlGaAs heterostructures capped by a 50nm50 {\rm nm}-thick InAs layer grown by molecular beam epitaxy and a 2μm2 {\rm \mu m}-thick InAs buffer layer on Si(111) obtained by vapor phase epitaxy. Morphological and structural properties of substrates and nanowires are analyzed by atomic force and transmission electron microscopy. Our results indicate a promising direction for the integration of III-V nanostructures on Si-based electronics as well as for the development of novel micromechanical structures.Comment: 5 pages, 5 figures, suppl.ma

    Reduction in the uncertainty of the neutron-capture cross section of 210Bi: Impact of a precise multipolarity measurement of the 2− → 1− main ground-state transition

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    International audience; The mixing ratio of the main 320-keV, M1 + E2 ground-state γ transition in 210Bi has been more precisely quantified, allowing a significant reduction in the uncertainty of measurements of the neutron-capture cross section to the ground state of 210Bi from 25% to 0.9%. Accurate values for neutron-capture cross sections to both the ground and long-lived 9− isomeric state at 271 keV in 210Bi are of particular importance as Pb-Bi finds increased usage in Accelerator Driven Systems

    Soil DNA metabarcoding: evaluating the efficiency of multiplex primer sets in recovering the soil invertebrate&apos;s community as soil quality indicators

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    DNA Metabarcoding was used to investigate the efficiency of two sets of primers (combinations A and B) for characterizing the soil invertebrate\u2019s communities in different farming management systems. Soil samples were taken from three different sites in the South-West of Milan and DNA was extracted directly. PCR was applied by using 4 pairs of previously published primers targeting invertebrate\u2019s cox1, followed by Illumina Miseq sequencing. The results showed that the presence of the most popular primer pair used in barcoding studies (LCOI490-HCO2198) has affected negatively the taxonomic assignment of OTUs, since about 67.88 % of the obtained sequences where not identified. Our analysis showed that a higher percentage of Arthropoda, Annelida, Nematoda and Rotifera &Tardigrada (41.6, 5.9, 0.8 and 1% of total reads, respectively) was obtained with primer combination B; thus this primers set can be considered a promising method to evaluate the soil arthropods community
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