116 research outputs found

    Stable and Unstable Operations in mod p Cohomology Theories

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    We consider operations between two multiplicative, complex orientable cohomology theories. Under suitable hypotheses, we construct a map from unstable to stable operations, left-inverse to the usual map from stable to unstable operations. In the main example, where the target theory is one of the Morava K-theories, this provides a simple and explicit description of a splitting arising from the Bousfield-Kuhn functorComment: 28 pages; corrected proof of proposition 3.2, other minor improvement

    Changing Patterns of Human Campylobacteriosis, England and Wales, 1990–2007

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    To explore hypotheses for age-related changes in the incidence of Campylobacter infections in England and Wales during 1990–2007, we analyzed electronic laboratory data. Disease incidence was reduced among children, and the greatest increase in risk was for those >60 years of age. Risk factors for campylobacteriosis in the elderly population should be identified

    Association between preterm brain injury and exposure to chorioamnionitis during fetal life

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    Preterm infants are susceptible to inflammation-induced white matter injury but the exposures that lead to this are uncertain. Histologic chorioamnionitis (HCA) reflects intrauterine inflammation, can trigger a fetal inflammatory response, and is closely associated with premature birth. In a cohort of 90 preterm infants with detailed placental histology and neonatal brain magnetic resonance imaging (MRI) data at term equivalent age, we used Tract-based Spatial Statistics (TBSS) to perform voxel-wise statistical comparison of fractional anisotropy (FA) data and computational morphometry analysis to compute the volumes of whole brain, tissue compartments and cerebrospinal fluid, to test the hypothesis that HCA is an independent antenatal risk factor for preterm brain injury. Twenty-six (29%) infants had HCA and this was associated with decreased FA in the genu, cingulum cingulate gyri, centrum semiovale, inferior longitudinal fasciculi, limbs of the internal capsule, external capsule and cerebellum (p < 0.05, corrected), independent of degree of prematurity, bronchopulmonary dysplasia and postnatal sepsis. This suggests that diffuse white matter injury begins in utero for a significant proportion of preterm infants, which focuses attention on the development of methods for detecting fetuses and placentas at risk as a means of reducing preterm brain injury
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