730 research outputs found

    Winning the Obesity Battle

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    Winning the Obesity Battl

    Reducing Disparities by way of a Cancer Disparities Research Training Program

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    Background: For minority populations, there is a continuing disparity in the burden of death and illness from cancer. Research to address this disparity should be conducted by investigators who can best understand and address the needs of culturally diverse communities. However, minorities are under-represented in health-related research. The goal of this project was to develop and evaluate an approach to motivating and preparing master’s degree students for careers dedicated to cancer disparities research. Method: A Cancer Disparities Research Training Program (CDRTP) was initiated in 2010. The program consists of coursework, practicum experiences, and research opportunities. Assessment of the curriculum is based on monitoring achievement of evaluation indicators and includes a quantitative assessment and qualitative approach. Results: In its first three years, the program graduated 20 trainees, all of whom were minorities (18 African Americans and two Asians). When asked about career goals, two-thirds of the trainees indicated interest in pursuing careers in research on cancer prevention and control. The trainees expressed high satisfaction with the courses, instructor, materials, and curriculum. Although trainees had suggestions about course details, evaluations overall were positive. Across focus groups, three recurrent themes emerged regarding activities to enhance the student experience: having a wider variety of topics, more guest speakers, and field trips. Conclusion: The CDRTP was intended to recruit students – primarily African Americans – into research on prevention and control of cancer disparities. Although final evaluation of the program’s overall outcome will not be available for several years, a preliminary evaluation indicates the program is being successful

    Chip-Scale, Sub-Hz Fundamental Sub-kHz Integral Linewidth 780 nm Laser through Self-Injection-Locking a Fabry-P\'erot laser to an Ultra-High Q Integrated Resonator

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    Today's state of the art precision experiments in quantum, gravimetry, navigation, time keeping, and fundamental science have strict requirements on the level and spectral distribution of laser frequency noise. For example, the laser interaction with atoms and qubits requires ultra-low frequency noise at multiple offset frequencies due to hyperfine atomic transitions, motional sidebands, and fast pulse sequencing. Chip-scale integration of lasers that meet these requirements is essential for reliability, low-cost, and weight. Here, we demonstrate a significant advancement in atomic precision light sources by realizing a chip-scale, low-cost, 780 nm laser for rubidium atom applications with record-low 640 mHz (white noise floor at 0.2 Hz2^2/Hz) fundamental and 732 Hz integral linewidths and a frequency noise that is multiple orders of magnitude lower than previous hybrid and heterogeneous self-injection locked 780 nm lasers and lower noise than bulk microresonator implementations. The laser is a Fabry-P\'erot laser diode self-injection locked to an ultra-high Q photonic integrated silicon nitride resonator. This performance is enabled by a 145 million resonator Q with a 30 dB extinction ratio, the highest Q at 780 nm, to the best of our knowledge. We analyze the impact of our frequency noise on specific atomic applications including atomic frequency references, Rydberg quantum gates, and cold atom gravimeters. The photonic integrated resonator is fabricated using a CMOS foundry-compatible, wafer-scale process, with demonstrated integration of other components showing promise for a full system-on-a-chip. This performance is scalable to other visible atomic wavelengths, opening the door to a variety of transitions across many atomic species and enabling low-power, compact, ultra-low noise lasers impacting applications including quantum sensing, computing, clocks and more

    Fundamental noise dynamics in cascaded-order Brillouin lasers

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    The dynamics of cascaded-order Brillouin lasers make them ideal for applications such as rotation sensing, highly coherent optical communications, and low-noise microwave signal synthesis. Remark- ably, when implemented at the chip-scale, recent experimental studies have revealed that Brillouin lasers can operate in the fundamental linewidth regime where optomechanical and quantum noise sources dominate. To explore new opportunities for enhanced performance, we formulate a simple model to describe the physics of cascaded Brillouin lasers based on the coupled mode dynamics governed by electrostriction and the fluctuation-dissipation theorem. From this model, we obtain analytical formulas describing the steady state power evolution and accompanying noise properties, including expressions for phase noise, relative intensity noise and power spectra for beat notes of cascaded laser orders. Our analysis reveals that cascading modifies the dynamics of intermediate laser orders, yielding noise properties that differ from single-mode Brillouin lasers. These modifications lead to a Stokes order linewidth dependency on the coupled order dynamics and a broader linewidth than that predicted with previous single order theories. We also derive a simple analytical expression for the higher order beat notes that enables calculation of the Stokes linewidth based on only the relative measured powers between orders instead of absolute parameters, yielding a method to measure cascaded order linewidth as well as a prediction for sub-Hz operation. We validate our results using stochastic numerical simulations of the cascaded laser dynamics.Comment: 18 pages, 9 figure

    The Small Scale Anisotropies, the Spectrum and the Sources of Ultra High Energy Cosmic Rays

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    We calculate the number density and luminosity of the sources of ultra high energy cosmic rays (UHECRs), using the information about the small scale anisotropies and the observed spectra. We find that the number of doublets and triplets observed by AGASA can be best reproduced for a source density of 105Mpc3\sim 10^{-5} Mpc^{-3}, with large uncertainties. The spectrum of UHECRs implies an energy input of 6×1044ergyr1Mpc3\sim 6\times 10^{44} erg yr^{-1} Mpc^{-3} above 101910^{19} eV and an injection spectrum E2.6\propto E^{-2.6}. A flatter injection spectrum, E2.4E^{-2.4}, can be adopted if the sources have luminosity evolution (1+z)4\propto (1+z)^4. The combination of these two pieces of information suggests that the single sources should on average have a cosmic ray luminosity above 101910^{19} eV of Lsource2×1042ergs1L_{source}\approx 2\times 10^{42} erg s^{-1}, weakly dependent upon the injection spectrum. Unfortunately, with the limited statistics of events available at present, there are approximately one-two orders of magnitude uncertainty in the source density provided above. We make predictions on the expected performances of the Auger and EUSO experiments, with particular attention for the expected improvements in our understanding of the nature of the sources of UHECRs. We find that a critical experimental exposure Σc\Sigma_c exists, such that experiments with exposure larger than Σc\Sigma_c can detect at least one event from each source at energies above 102010^{20} eV. This represents a unique opportunity to directly count and identify the sources of UHECRs.Comment: Submitted to Astropart. Phy
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