Cryptococcal choroiditis in advanced AIDS with clinicopathologic correlation.

PurposeTo describe a case of disseminated cryptococcal meningitis with multifocal choroiditis and provide optical coherence tomography (OCT) findings correlated with described histopathology in a patient with advanced acquired immunodeficiency syndrome (AIDS).ObservationsThe patient was a 54-year-old man with AIDS who presented with dyspnea and headache followed by acute vision loss. OCT demonstrated a lesion with a small area of fluid that was limited by a more prominent and irregular external limiting membrane with underlying nodular choroidal thickening, mild RPE disorganization, and hyperreflectivity of the overlying photoreceptor layer. Patient was found to have disseminated cryptococcal infection and passed away despite aggressive therapy. Autopsy was performed including bilateral enucleation and a Cryptococcus lesion was confirmed on histopathology.Conclusion and importanceThis case highlights the clinical, imaging, and histopathologic findings of cryptococcal choroiditis and provides a review of the updated treatment recommendations for disseminated infection in a patient with advanced AIDS. Although currently fundoscopy has proven most useful in directing the diagnostic algorithm in choroiditis in the setting of advanced immunosuppression, OCT may provide insight into the spread of Cryptococcus within the eye

Family centred care before and during life-sustaining treatment withdrawal in intensive care: A survey of information provided to families by Australasian critical care nurses

publisher: Elsevier articletitle: Family centred care before and during life-sustaining treatment withdrawal in intensive care: A survey of information provided to families by Australasian critical care nurses journaltitle: Australian Critical Care articlelink: http://dx.doi.org/10.1016/j.aucc.2016.08.006 content_type: article copyright: © 2016 Australian College of Critical Care Nurses Ltd. Published by Elsevier Ltd. All rights reserved

Nonlocal restoration of two-mode squeezing in the presence of strong optical loss

We present the experimental realization of a theoretical effect discovered by Olivares and Paris, in which a pair of entangled optical beams undergoing independent losses can see nonlocal correlations restored by the use of a nonlocal resource correlating the losses. Twin optical beams created in an entangled Einstein-Podolsky-Rosen (EPR) state by an optical parametric oscillator above threshold were subjected to 50% loss from beamsplitters in their paths. The resulting severe degradation of the signature quantum correlations observed between the two beams was then suppressed when another, independent EPR state impinged upon the other input ports of the beamsplitters, effectively entangling the losses inflicted to the initial EPR state. The additional EPR beam pair was classically coherent with the primary one but had no quantum correlations with it. This result may find applications as a quantum tap for entanglement.Comment: 14 pages, 6 figures, submitted for publicatio

Torsion, an alternative to dark matter?

We confront Einstein-Cartan's theory with the Hubble diagram. An affirmative answer to the question in the title is compatible with today's supernovae data.Comment: 14 pp, 3 figures. Version 2 matches the version published in Gen. Rel. Grav., references added. Version 3 corrects a factor 3 in Cartan's equations to become

Report of the multidisciplinary investigation of differentiation and potential hybridisation between two Yellowfish species Labeobarbus Kimberleyensis and L. Aeneus from the Orange-Vaal system

From the executive summary]: The relationships within and between two yellowfish species, Labeobarbus aeneus (smallmouth yellowfish) and L. kimberleyensis (largemouth yellowfish) from the Orange-Vaal system were investigated through three independently conducted studies of the same material collected from the Sak River (the type locality of L. aeneus), the upper Orange River at Aliwal North and the lower Orange River at Pella and Onseepkans

Real-Gas Effects and Phase Separation in Underexpanded Jets at Engine-Relevant Conditions

A numerical framework implemented in the open-source tool OpenFOAM is presented in this work combining a hybrid, pressure-based solver with a vapor-liquid equilibrium model based on the cubic equation of state. This framework is used in the present work to investigate underexpanded jets at engine-relevant conditions where real-gas effects and mixture induced phase separation are probable to occur. A thorough validation and discussion of the applied vapor-liquid equilibrium model is conducted by means of general thermodynamic relations and measurement data available in the literature. Engine-relevant simulation cases for two different fuels were defined. Analyses of the flow field show that the used fuel has a first order effect on the occurrence of phase separation. In the case of phase separation two different effects could be revealed causing the single-phase instability, namely the strong expansion and the mixing of the fuel with the chamber gas. A comparison of single-phase and two-phase jets disclosed that the phase separation leads to a completely different penetration depth in contrast to single-phase injection and therefore commonly used analytical approaches fail to predict the penetration depth.Comment: Preprint submitted to AIAA Scitech 2018, Kissimmee, Florid

Broadband amplitude squeezing in a periodically poled KTiOPO_4 waveguide

We generated -2.2 dB of broadband amplitude squeezing at 1064 nm in a periodically poled KTiOPO_4 (PPKTP) waveguide, by coupling of the fundamental and second harmonic continuous-wave fields. This is the largest amount of squeezing obtained to date in a KTP waveguide, limited by propagation losses. This result paves the way for further improvements by use of lower-loss buried ion-exchanged waveguides.Comment: 3 pages, 2 figures, submitted for publicatio

Collaboration and contestation in further and higher education partnerships in England: a Bourdieusian field analysis

Internationally, ‘College for All’ policies are creating new forms of vocational higher education (HE), and shifting relationships between HE and further education (FE) institutions. In this paper, we consider the way in which this is being implemented in England, drawing on a detailed qualitative case study of a regional HE–FE partnership to widen participation. We focus on the complex mix of collaboration and contestation that arose within it, and how these affected socially differentiated groups of students following high- and low-status routes through its provision. We outline Bourdieu’s concept of ‘field’ as a framework for our analysis and interpretation, including its theoretical ambiguities regarding the definition and scale of fields. Through hermeneutic dialogue between data and theory, we tentatively suggest that such partnerships represent bridges between HE and FE. These bridges are strong between higher-status institutions, but highly contested between lower-status institutions competing closely for distinction. We conclude that the trajectories and outcomes for socially disadvantaged students require attention and collective action to address the inequalities they face, and that our theoretical approach may have wider international relevance beyond the English case

Exploring the promotion of youth voice and activism by youth development workers in community-based programs.

Youth-adult partnerships (Y-APs) and youth voice promotion are best practices within the youth development sector, but youth development workers receive little training or guidance in employing these concepts. A scarcity of research explores the relationships between organizational supports, as demonstrated by training, supervision, evaluation, and worker engagement in promoting youth voice. The two studies within this dissertation investigated the social processes of how and why youth development workers promoted youth voice. Program participants were primarily youth of color living in areas of high multidimensional poverty. They also explored how and why organizational factors impacted the promotion of youth voice within programmatic contexts. Three aims were established in pursuit of this goal: 1) describe the relationship between organizational support, as demonstrated by job clarity and supervision, and youth development worker promotion of youth voice 2) develop a context-specific framework describing the necessary conditions for high youth voice promotion and 3) develop a context-specific framework describing the social process of youth development workers promoting youth voice while experiencing varying degrees of organization support. Questions supporting these aims included: 1) What processes do youth development workers engage in when promoting youth voice? 2) What strategies do youth development workers employ when they face barriers in promoting youth voice? Furthermore, 3) How do youth development workers make meaning of their role within the organization and program? The approach to these studies was Constructivist Grounded Theory aided by Situational Analysis, which included methods of coding, memoing, relational and positional mapping, using in-depth interviews with 19 youth development workers. Results of Chapter 2 indicated that sharing experiences and internalizing social justice youth development principles resulted in adopting roles more congruent with high youth voice promotion. Organizational policies and restrictions acted as barriers for workers in promoting youth voice when they restricted flexibility in programmatic development. A context-specific framework entitled Internalizing Social Justice Youth Development Principles: Conditions for Promoting High Levels of Youth Voice Programs” was produced. Results of Chapter 3 indicated a relationship between job role clarity and perceptions of self-efficacy for youth development workers in navigating conflict within programming. Higher levels of perceived self-efficacy led workers to adopt the stance love them through it and promote higher levels of individual youth voice. External factors, such as funding entities and youth development models, influenced the conceptualization of job roles for workers and led to the adoption of more educationally based foci. A context-specific framework entitled Promoting Youth Voice: The Influence of Role Identity and Self-Efficacy in Youth-Adult Relationships” resulted from findings