States with a history of undemocratic regimes in the 20th century are more likely to repress racist movements.

Why do some liberal democracies repress racist associations, while others tolerate their existence? Erik Bleich outlines the results of a study into the different factors that affect a state’s response to racist political parties and movements. He finds that the most significant predisposing factor to states placing restrictions on racist associations is a history of undemocratic regimes in the 20th century. The trigger for a country choosing to pass or enforce such provisions varies, however, with external pressure from international bodies, and a rise in domestic racist incidents being two of the most common precipitating events

Faith and state. British policy responses to Islamist extremism

El extremismo islámico ha sido objeto de intenso escrutinio global desde septiembre de 2001. Muchos Estados han respondido al desafío del terrorismo islámico con una estrategia antiterrorista común. Tal estrategia incluye políticas genéricas anti violenciIslamist extremism has been the focus of intensive global scrutiny since September 2001. Many states have responded to the challenge of Islamic terrorism with a common anti terrorist strategy. Those policies include generic anti violence policies that co

Media coverage of Muslims: Introduction and overview

Existing research largely concurs that coverage of Muslims is negative. Yet this masks how much remains unknown. In particular, there has been no clear or consistent way to gauge precisely how much negativity is present in stories about Muslims. This chapter introduces a systematic way to assess the tone of articles and discusses how this allows for answers to six important questions about coverage of Muslims. The chapter also outlines the structure of the book and summarizes the key findings. In particular, it argues that coverage of Muslims is strikingly negative by every comparative measure examined.https://scholarworks.wm.edu/asbookchapters/1139/thumbnail.jp

Atheism in US and UK Newspapers: Negativity about Non-Belief and Non-Believers

Atheists are among the most disliked “religious” groups in the United States, but the origins of this aversion remain poorly understood. Because the media are an important source of public attitudes, we analyze coverage of atheism and atheists in American and British newspapers. Using computational text analysis techniques, including sentiment analysis and topic modeling, we show that atheism is portrayed negatively by the print media. Significantly, we show that greater negativity is associated with atheism as a concept than with atheists as individuals. Building on this insight, and challenging arguments that prominent atheist intellectuals attract negative coverage, we also find that coverage of famous atheists is actually more positive than that of atheists or atheism in general. Overall, our findings add a new dimension to scholarship on differences between individual-targeted and group-targeted tolerance in public attitudes, establishing for the first time that media coverage mirrors such differences

Media Coverage of Muslim Devotion: A Four-Country Analysis of Newspaper Articles, 1996–2016

Scholars have identified Muslims’ religiosity and faith practices, often believed to be more intense than those of other religious groups, as a point of friction in liberal democracies. We use computer-assisted methods of lexical sentiment analysis and collocation analysis to assess more than 800,000 articles between 1996 and 2016 in a range of British, American, Canadian, and Australian newspapers. We couple this approach with human coding of 100 randomly selected articles to investigate the tone of devotion-related themes when linked to Islam and Muslims. We show that articles touching on devotion are not as negative as articles about other aspects of Islam—and indeed that they are not negative at all, on average, when focused on a key subset of devotion-related articles. We thus offer a new perspective on the perception of Islamic religiosity in Western societies. Our findings also suggest that if newspapers strive to provide a more balanced portrayal of Muslims and Islam within their pages, they may seek opportunities to include more frequent mentions of Muslim devotion

How secularized is Germany? Cohort and comparative perspectives

"The author seeks to answer the question 'How secularized is Germany?' on the basis of different perspectives and databases. The meaning of the term secularization is limited for this study to the decline of religiosity and its consequences, and a distinction is made between church-related and individual religiosity. First, evidence for the decline of church-related religiosity in Germany is presented. Next, it is shown that individual religiosity, i.e. religiosity not necessarily related to organized religion, is also declining. Then the analysis is extended to investigate the relationship between religiosity and non-religious attitudes. Taking two illustrative examples, it is claimed that religion today is far less salient for the way we live and see the world than it has been in the past. Finally, the focus of the analysis is broadened to an international perspective in which Germany is compared with other countries. The author ends with some thoughts on the future of secularization in Germany." (author's abstract

Can Gene Expression Analysis in Zero-Time Biopsies Predict Kidney Transplant Rejection?

Zero-time biopsies are taken to determine the quality of the donor organ at the time of transplantation. Histological analyses alone have so far not been able to identify parameters that allow the prediction of subsequent rejection episodes or graft survival. This study investigated whether gene expression analyses of zero-time biopsies might support this prediction. Using a well-characterized cohort of 26 zero-time biopsies from renal transplant patients that include 4 living donor (LD) and 22 deceased donor (DD) biopsies that later developed no rejection (Ctrl, n = 7), delayed graft function (DGF, n = 4), cellular (T-cell mediated rejection; TCMR, n = 8), or antibody-mediated rejection (ABMR, n = 7), we analyzed gene expression profiles for different types of subsequent renal transplant complication. To this end, RNA was isolated from formalin-fixed, paraffin-embedded (FFPE) sections and gene expression profiles were quantified. Results were correlated with transplant data and B-cell, and plasma cell infiltration was assessed by immunofluorescence microscopy. Both principal component analysis and clustering analysis of gene expression data revealed marked separation between LDs and DDs. Differential expression analysis identified 185 significant differentially expressed genes (adjusted p < 0.05). The expression of 68% of these genes significantly correlated with cold ischemia time (CIT). Furthermore, immunoglobulins were differentially expressed in zero-time biopsies from transplants later developing rejection (TCMR + ABMR) compared to non-rejected (Ctrl + DGF) transplants. In addition, immunoglobulin expression did not correlate with CIT but was increased in transplants with previous acute renal failure (ARF). In conclusion, gene expression profiles in zero-time biopsies derived from LDs are markedly different from those of DDs. Pre-transplant ARF increased immunoglobulin expression, which might be involved in triggering later rejection events. However, these findings must be confirmed in larger cohorts and the role of early immunoglobulin upregulation in zero-biopsies needs further clarification

シンポジウム『ヘイト・スピーチはどこまで規制できるか』

1. シンポジウム『ヘイト・スピーチはどこまで規制できるか』　企画・司会　東川浩二2. 基調講演「ヘイト・スピーチとは何か」　エリック・ブライシュ/　東川浩二(訳)3.「ヘイトスピーチ事案における不法行為法・填補賠償法理の担う役割の再評価～京都・徳島事件を題材に、反差別（差別被害への共感醸成）の運動展開の文脈において」　弁護士　冨増四季4. ヘイトスピーチ規制賛成論に対するいくつかの疑問　ー憲法学的観点、政治学的観点、哲学的観点のそれぞれからー　駒村圭吾5. ヘイト・スピーチと「公の施設」　川崎市ガイドラインを素材として　奈須祐

Design and baseline characteristics of the finerenone in reducing cardiovascular mortality and morbidity in diabetic kidney disease trial

Background: Among people with diabetes, those with kidney disease have exceptionally high rates of cardiovascular (CV) morbidity and mortality and progression of their underlying kidney disease. Finerenone is a novel, nonsteroidal, selective mineralocorticoid receptor antagonist that has shown to reduce albuminuria in type 2 diabetes (T2D) patients with chronic kidney disease (CKD) while revealing only a low risk of hyperkalemia. However, the effect of finerenone on CV and renal outcomes has not yet been investigated in long-term trials. Patients and Methods: The Finerenone in Reducing CV Mortality and Morbidity in Diabetic Kidney Disease (FIGARO-DKD) trial aims to assess the efficacy and safety of finerenone compared to placebo at reducing clinically important CV and renal outcomes in T2D patients with CKD. FIGARO-DKD is a randomized, double-blind, placebo-controlled, parallel-group, event-driven trial running in 47 countries with an expected duration of approximately 6 years. FIGARO-DKD randomized 7,437 patients with an estimated glomerular filtration rate >= 25 mL/min/1.73 m(2) and albuminuria (urinary albumin-to-creatinine ratio >= 30 to <= 5,000 mg/g). The study has at least 90% power to detect a 20% reduction in the risk of the primary outcome (overall two-sided significance level alpha = 0.05), the composite of time to first occurrence of CV death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for heart failure. Conclusions: FIGARO-DKD will determine whether an optimally treated cohort of T2D patients with CKD at high risk of CV and renal events will experience cardiorenal benefits with the addition of finerenone to their treatment regimen. Trial Registration: EudraCT number: 2015-000950-39; ClinicalTrials.gov identifier: NCT02545049