"Both Count and King: Composite Lordship in Thirteenth-Century Champagne and Navarre"

This dissertation examines how the counts of Champagne in northeastern France simultaneously ruled Champagne and the Iberian kingdom of Navarre from 1234 to 1274. Count Thibaut IV of Champagne (r. 1201-1253) inherited Navarre when his maternal uncle, King Sancho VII (r. 1194-1234), died childless. Because thirteenth-century Champagne and Navarre were culturally, linguistically, and geographically separate, the &ldquo;count-kings&rdquo; developed administrative practices to maintain and assert their sovereignty and lordship despite always being absent from at least one of their principalities. This dissertation analyzes and interprets how they successfully administered both regions and cultivated relationships with their people even when they were not physically present. Based on extensive archival research, this dissertation uses charters, letters, papal bulls, financial accounts, and inquests from both Champagne and Navarre to determine what strategies the count-kings used to govern, who ran their administration, and how they proclaimed their sovereignty. It argues that the count-kings made their presence felt in their absence through grants of protection and by employing a robust cadre of officials to act in their stead. Likewise, their many foundations and building projects made them a physical part of the landscape of Champagne-Navarre, while indulgences explicitly linked to them made them part of their people&rsquo;s devotion.</p

Depression in Student Athletes: A Particularly At-Risk Group? A Systematic Review of the Literature

Mental health initiatives are being implemented based on collegiate athletes being a high risk subculture for a variety of health behaviors that correlate directly to depression. This literature review used the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) method to investigate the association between depression and student athletes. An initial search of the research databases yielded 807 articles. After applying additional delimiting criteria, 30 articles were considered relevant for the critical review and 11 for the systematic review. Results showed that student athletes are actually less likely to be depressed when compared to their non-athlete peers due to protective factors including levels of self-esteem and confidence, social support, and connectedness. However, there were distinct differences among collegiate athletes in how depression manifests and factors that serve as barriers to treatment. It is important for coaches, parents, teachers, peers, and those working with athletes to be able to recognize factors that may influence depression among this population as well as barriers that may instigate the adoption of risky health behaviors and inhibit them from seeking help

Pilot Source Study: An Analysis of Pilot Backgrounds and Subsequent Success in US Regional Airline Training Programs

The 2010 Pilot Source Study, commissioned to research the success of pilots in initial training for Part 121 operations, analyzed the training performance of 2,156 new-hire pilots in the years 2005-2009. Six regional airlines provided data that was mined from human resource and pilot training files. Five university researchers independently analyzed the data and integrated their results. The study expressed success in terms of fewer extra training events and fewer non-completions in regional airline training. Statistically, the best performing pilots were those who had flight instructor certificates, graduated from collegiate accredited flight programs, received advanced (post-Private) pilot training in college, graduated with collegiate aviation degrees (any aviation discipline), and had between 500 and 1,000 pre-employment flight hours. Pilot source characteristics that had no significance in regional airline pilot training success were: having a non-aviation college degree and having prior corporate pilot or airline pilot experience

Once-through CANDU reactor models for the ORIGEN2 computer code

Reactor physics calculations have led to the development of two CANDU reactor models for the ORIGEN2 computer code. The model CANDUs are based on (1) the existing once-through fuel cycle with feed comprised of natural uranium and (2) a projected slightly enriched (1.2 wt % /sup 235/U) fuel cycle. The reactor models are based on cross sections taken directly from the reactor physics codes. Descriptions of the reactor models, as well as values for the ORIGEN2 flux parameters THERM, RES, and FAST, are given

Variation in albedo and other vegetation characteristics in non-forested northern ecosystems: the role of lichens and mosses

Vegetation has a profound impact on climate through complex interactions and feedback loops, where especially regulation of albedo, the ratio of reflected to incoming solar radiation, is important at high latitudes. How vegetation albedo varies along environmental gradients in tundra ecosystems is still not well understood, particularly for ecosystems dominated by nonvascular vegetation. We studied broadband shortwave albedo of open boreal, arctic, and alpine ecosystems over a 2000 km long latitudinal gradient (60◦ N–79◦ N) and contrasted this against species composition, vegetation greenness (normalised difference vegetation index—NDVI), momentary ecosystem CO2 fluxes and reindeer (Rangifer tarandus) grazing pressure. High cover of pale terricolous fruticose lichens was the single most important predictor for vegetation albedo, which had a maximum value of 0.389 under clear sky conditions and solar zenith angle 60◦. To our knowledge, this is the highest broadband albedo recorded for a vegetated surface. NDVI was negatively correlated to lichen biomass (rs = −0.56), and albedo (rs = −0.19). Gross primary production and ecosystem respiration varied considerably less between plots and vegetation types than albedo. While it is well-known that Rangifer affects climate-relevant aboveground biomass, we here show that its regulation of surface albedo in northern ecosystems may also be of high importance for land-atmosphere interactions. The data presented here thus advocate for an increased understanding of the important and complex role of herbivores and lichen cover in climate-vegetation interactions.publishedVersio

Role of macrophage migration inhibitory factor (MIF) in allergic and endotoxin-induced airway inflammation in mice.

Macrophage migration inhibitory factor (MIF) has recently been forwarded as a critical regulator of inflammatory conditions, and it has been hypothesized that MIF may have a role in the pathogenesis of asthma and chronic obstructive pulmonary disease (COPD). Hence, we examined effects of MIF immunoneutralization on the development of allergen-induced eosinophilic inflammation as well as on lipopolysaccharide (LPS)-induced neutrophilic inflammation in lungs of mice. Anti-MIF serum validated with respect to MIF neutralizing capacity or normal rabbit serum (NRS) was administered i.p. repeatedly during allergen aerosol exposure of ovalbumin (OVA)-immunized mice in an established model of allergic asthma, or once before instillation of a minimal dose of LPS into the airways of mice, a tentative model of COPD. Anti-MIF treatment did not affect the induced lung tissue eosinophilia or the cellular composition of bronchoalveolar lavage fluid (BALF) in the asthma model. Likewise, anti-MIF treatment did not affect the LPS-induced neutrophilia in lung tissue, BALF, or blood, nor did it reduce BALF levels of tumor necrosis factor-alpha (TNF-alpha) and macrophage inflammatory protein-1alpha (MIP-1alpha). The present data suggest that MIF is not critically important for allergen-induced eosinophilic, and LPS-induced neutrophilic responses in lungs of mice. These findings do not support a role of MIF inhibition in the treatment of inflammatory respiratory diseases

The creation view of opportunities at the base of the pyramid

This research aims to understand how multinational corporations (MNCs) enter the base of the pyramid (BoP) by adopting the creation view of opportunities. We employ actor–network theory and explore the key actors, the process and the opportunity development that enable MNCs to tackle the relative poverty of the BoP market. Our qualitative exploratory case study illustrates that, at the BoP, MNCs have to involve beneficiary stakeholders such as non-governmental organizations and BoP communities. In this process, they should be open to modifying their business model continuously to build awareness about the product among the poor and ensure affordability, availability and acceptability. At the BoP, opportunities do not exist in the external environment and they should be developed by identifying and addressing the real needs of the poor, enhancing their quality of life and being patient about earning a profit. This research contributes to the entrepreneurship literature by expanding the creation perspective of opportunities and provides implications for the managers of companies targeting the BoP market

Shared CSF Biomarker Profile in Idiopathic Normal Pressure Hydrocephalus and Subcortical Small Vessel Disease

Introduction: In this study, we examine similarities and differences between 52 patients with idiopathic normal pressure hydrocephalus (iNPH) and 17 patients with subcortical small vessel disease (SSVD), in comparison to 28 healthy controls (HCs) by a panel of cerebrospinal fluid (CSF) biomarkers. Methods: We analyzed soluble amyloid precursor protein alpha (sAPPα) and beta (sAPPβ), Aβ isoforms −38, −40, and −42, neurofilament light protein (NFL), glial fibrillary acidic protein (GFAP), myelin basic protein (MBP), matrix metalloproteinases (MMP −1, −2, −3, −9, and −10), and tissue inhibitors of metalloproteinase 1 (TIMP1). Radiological signs of white matter damage were scored using the age-related white matter changes (ARWMC) scale. Results: All amyloid fragments were reduced in iNPH and SSVD (p < 0.05), although more in iNPH than in SSVD in comparison to HC. iNPH and SSVD showed comparable elevations of NFL, MBP, and GFAP (p < 0.05). MMPs were similar in all three groups except for MMP-10, which was increased in iNPH and SSVD. Patients with iNPH had larger ventricles and fewer WMCs than patients with SSVD. Conclusion: The results indicate that patients with iNPH and SSVD share common features of subcortical neuronal degeneration, demyelination, and astroglial response. The reduction in all APP-derived proteins characterizing iNPH patients is also present, indicating that SSVD encompasses similar pathophysiological phenomena as iNPH

Corporate Culture and Its Connection with External and Internal Public Relations

The main aim of this article is to present the influence of corporate culture on company's stakeholders. This paper signalises the tendency in corporate communication with its internal and external publics. It is focused on two issues: corporate social responsibility and employer branding. Those two categories are consequences of corporate culture model.Głównym celem artykułu jest zaprezentowanie wpływu jaki wywiera charakter kultury korporacyjnej na związanych z przedsiębiorstwem interesariuszy (stakeholders). W artykule zasygnalizowane zostały główne tendencje wyznaczające charakter komunikacji między organizacją a jej wewnętrznym i zewnętrznym otoczeniem. Tekst koncentruje się na dwóch kwestiach: społecznej odpowiedzialności przedsiębiorstwa (corporate social responsibilty) i budowanie wizerunku pracodawcy (employer branding), które zaprezentowane zostały jako efekty określonego modelu kultury organizacyjnej