Digital Interventions Supporting Self-care in People With Type 2 Diabetes Across Greater Manchester (Greater Manchester Diabetes My Way):Protocol for a Mixed Methods Evaluation

BACKGROUND: Type 2 Diabetes (T2D) is common, with a prevalence of approximately 7% of the population in the United Kingdom. The quality of T2D care is inconsistent across the United Kingdom, and Greater Manchester (GM) does not currently achieve the National Institute for Health and Care Excellence treatment targets. Barriers to delivery of care include low attendance and poor engagement with local T2D interventions, which tend to consist of programs of education delivered in traditional, face-to-face clinical settings. Thus, a flexible approach to T2D management that is accessible to people from different backgrounds and communities is needed. Diabetes My Way (DMW) is a digital platform that offers a comprehensive self-management and educational program that should be accessible to a wide range of people through mobile apps and websites. Building on evidence generated by a Scotland-wide pilot study, DMW is being rolled out and tested across GM. OBJECTIVE: The overarching objectives are to assess whether DMW improves outcomes for patients with T2D in the GM area, to explore the acceptability of the DMW intervention to stakeholders, and to assess the cost-effectiveness of the intervention. METHODS: A mixed methods approach will be used. We will take a census approach to recruitment in that all eligible participants in GM will be invited to participate. The primary outcomes will be intervention-related changes compared with changes observed in a matched group of controls, and the secondary outcomes will be within-person intervention-related changes. The cost-effectiveness analysis will focus on obtaining reliable estimates of how each intervention affects risk factors such as HbA1c and costs across population groups. Qualitative data will be collected via semistructured interviews and focus groups and organized using template analysis. RESULTS: As of May 10, 2021, a total of 316 participants have been recruited for the quantitative study and have successfully enrolled. A total of 278 participants attempted to register but did not have appropriate permissions set by the general practitioners to gain access to their data. In total, 10 participants have been recruited for the qualitative study (7 practitioners and 3 patients). An extension to recruitment has been granted for the quantitative element of the research, and analysis should be complete by December 2022. Recruitment and analysis for the qualitative study should be complete by December 2021. CONCLUSIONS: The findings from this study can be used both to develop the DMW system and improve accessibility and usability in more deprived populations generally, thus improving equity in access to support for T2D self-management. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/2623

Underwater Gliders at Memorial University: Summary of Deployments and Collected Data 2006 - 2020

Memorial University has over the past 15 years been involved in various ocean glider activities with deployments focused primarily on the Newfoundland Shelf and the Labrador Sea. For example, there are four deployments with glider data in the Labrador Sea. Partnerships with Fisheries and Oceans Canada and Ocean Gliders Canada have also resulted in deployments of Memorial's gliders in the Pacific. The data contain 14’663 mission kms, 620 deployment days and 25’108 individual glider profiles. L1 NETCDF files for every deployment archived on the Memorial University’s Glider Data server are made available publicly for scientific research. Deployments vary in duration and region. All files were processed with the SOCIB glider toolbox (Troupin et al., 2015), modified by Nicolai von Oppeln-Bronikowski, 2019 for MUN glider deployments

Earth Virtualization Engines (EVE)

To manage Earth in the Anthropocene, new tools, new institutions, and new forms of international cooperation will be required. Earth Virtualization Engines is proposed as an international federation of centers of excellence to empower all people to respond to the immense and urgent challenges posed by climate change

Qualitative data sharing and re-use for socio-environmental systems research: A synthesis of opportunities, challenges, resources and approaches

Researchers in many disciplines, both social and natural sciences, have a long history of collecting and analyzing qualitative data to answer questions that have many dimensions, to interpret other research findings, and to characterize processes that are not easily quantified. Qualitative data is increasingly being used in socio-environmental systems research and related interdisciplinary efforts to address complex sustainability challenges. There are many scientific, descriptive and material benefits to be gained from sharing and re-using qualitative data, some of which reflect the broader push toward open science, and some of which are unique to qualitative research traditions. However, although open data availability is increasingly becoming an expectation in many fields and methodological approaches that work on socio-environmental topics, there remain many challenges associated the sharing and re-use of qualitative data in particular. This white paper discusses opportunities, challenges, resources and approaches for qualitative data sharing and re-use for socio-environmental research. The content and findings of the paper are a synthesis and extension of discussions that began during a workshop funded by the National Socio-Environmental Synthesis Center (SESYNC) and held at the Center Feb. 28-March 2, 2017. The structure of the paper reflects the starting point for the workshop, which focused on opportunities, challenges and resources for qualitative data sharing, and presents as well the workshop outputs focused on developing a novel approach to qualitative data sharing considerations and creating recommendations for how a variety of actors can further support and facilitate qualitative data sharing and re-use. The white paper is organized into five sections to address the following objectives: (1) Define qualitative data and discuss the benefits of sharing it along with its role in socio-environmental synthesis; (2) Review the practical, epistemological, and ethical challenges regarding sharing such data; (3) Identify the landscape of resources available for sharing qualitative data including repositories and communities of practice (4) Develop a novel framework for identifying levels of processing and access to qualitative data; and (5) Suggest roles and responsibilities for key actors in the research ecosystem that can improve the longevity and use of qualitative data in the future.This work was supported by the National Socio-Environmental Synthesis Center (SESYNC) under funding received from the National Science Foundation DBI-1052875

Earth Virtualization Engines (EVE)

To manage Earth in the Anthropocene, new tools, new institutions, and new forms of international cooperation will be required. Earth Virtualization Engines is proposed as an international federation of centers of excellence to empower all people to respond to the immense and urgent challenges posed by climate change

Genomic assessment of quarantine measures to prevent SARS-CoV-2 importation and transmission

Mitigation of SARS-CoV-2 transmission from international travel is a priority. We evaluated the effectiveness of travellers being required to quarantine for 14-days on return to England in Summer 2020. We identified 4,207 travel-related SARS-CoV-2 cases and their contacts, and identified 827 associated SARS-CoV-2 genomes. Overall, quarantine was associated with a lower rate of contacts, and the impact of quarantine was greatest in the 16–20 age-group. 186 SARS-CoV-2 genomes were sufficiently unique to identify travel-related clusters. Fewer genomically-linked cases were observed for index cases who returned from countries with quarantine requirement compared to countries with no quarantine requirement. This difference was explained by fewer importation events per identified genome for these cases, as opposed to fewer onward contacts per case. Overall, our study demonstrates that a 14-day quarantine period reduces, but does not completely eliminate, the onward transmission of imported cases, mainly by dissuading travel to countries with a quarantine requirement

Prevention and protection: will the Domestic Abuse Act transform the response to domestic abuse in England and Wales?

Hailed as a landmark in the prevention of domestic abuse and the protection of victims, the much-anticipated Domestic Abuse Act 2021 was passed by the House of Commons in July 2020 and is expected to come into force later this year. This article considers the extent to which the raft of measures introduced under the new legislation will transform the response to domestic violence and abuse in England and Wales. The paper considers domestic violence and abuse to be a gendered phenomenon with roots in broader social and cultural conditions of inequality, with women being disproportionately impacted due to the role violence and abuse have in sustaining male dominance at a societal level. Recognition of this necessitates a gendered approach to addressing domestic violence and abuse, which in turn shifts the focus away from discrete incidents and on to a full programme of behaviours aimed at disempowering victims. Through a discussion of the major provisions, the paper will argue that while the Act is a welcome addition and has clear potential to improve prevention and protection for individual victims, much more is needed in order to truly transform the response to domestic abuse in England and Wales

Blue Evening

https://digitalcommons.library.umaine.edu/mmb-vp-copyright/5561/thumbnail.jp

Acute effects of chocolate milk and a commercial recovery beverage on postexercise recovery indices and endurance cycling performance

To maximize training quality, athletes have sought nutritional supplements that optimize recovery. This study compared chocolate milk (CHOC) with a carbohydrate replacement beverage (CRB) as a recovery aid after intense exercise, regarding performance and muscle damage markers in trained cyclists. Ten regional-level cyclists and triathletes (maximal oxygen uptake 55.2 7.2mLkg1min1) completed a high-intensity intermittent exercise protocol, then 1518h later performed a performance trial at 85% of maximal oxygen uptake to exhaustion. Participants consumed 1.0 g carbohydratekg1h1 of a randomly assigned isocaloric beverage (CHOC or CRB) after the first high-intensity intermittent exercise session. The same protocol was repeated 1 week later with the other beverage. A 1-way repeated measures analysis of variance revealed no significant difference (p = 0.91) between trials for time to exhaustion at 85% of maximal oxygen uptake (CHOC 13 10.2min, CRB 13.5 8.9min). The change in creatine kinase (CK) was significantly (p\u3c 0.05) greater in the CRB trial than in the CHOC trial (increase CHOC 27.9 134.8 UL1, CRB 211.9 192.5 UL1), with differences not significant for CK levels before the second exercise session (CHOC 394.8 166.1 UL1, CRB 489.1 264.4UL1) between the 2 trials. These findings indicate no difference between CHOC and this commercial beverage as potential recovery aids for cyclists between intense workouts