96 research outputs found

    Using Semantic Technologies in Digital Libraries- A Roadmap to Quality Evaluation

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    Abstract. In digital libraries semantic techniques are often deployed to reduce the expensive manual overhead for indexing documents, maintaining metadata, or caching for future search. However, using such techniques may cause a decrease in a collection’s quality due to their statistical nature. Since data quality is a major concern in digital libraries, it is important to be able to measure the (loss of) quality of metadata automatically generated by semantic techniques. In this paper we present a user study based on a typical semantic technique use

    lncRNA-Induced Spread of Polycomb Controlled by Genome Architecture, RNA Abundance, and CpG Island DNA

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    Long noncoding RNAs (lncRNAs) cause Polycomb repressive complexes (PRCs) to spread over broad regions of the mammalian genome. We report that in mouse trophoblast stem cells, the Airn and Kcnq1ot1 lncRNAs induce PRC-dependent chromatin modifications over multi-megabase domains. Throughout the Airn-targeted domain, the extent of PRC-dependent modification correlated with intra-nuclear distance to the Airn locus, preexisting genome architecture, and the abundance of Airn itself. Specific CpG islands (CGIs) displayed characteristics indicating that they nucleate the spread of PRCs upon exposure to Airn. Chromatin environments surrounding Xist, Airn, and Kcnq1ot1 suggest common mechanisms of PRC engagement and spreading. Our data indicate that lncRNA potency can be tightly linked to lncRNA abundance and that within lncRNA-targeted domains, PRCs are recruited to CGIs via lncRNA-independent mechanisms. We propose that CGIs that autonomously recruit PRCs interact with lncRNAs and their associated proteins through three-dimensional space to nucleate the spread of PRCs in lncRNA-targeted domains. Schertzer et al. studied relationships between long noncoding RNAs (lncRNAs) and Polycomb repressive complexes (PRCs) in mouse trophoblast stem cells. They found that genome architecture, lncRNA abundance, and CpG island DNA each play important roles in dictating the intensity of PRC-induced chromatin modifications within lncRNA target domains

    Characterizing the Sensitivity of 40 GHz TES Bolometers for BICEP Array

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    The BICEP/Keck (BK) experiment aims to detect the imprint of primordial gravitational waves in the cosmic microwave background polarization, which would be direct evidence of the inflation theory. While the tensor-to-scalar ratio has been constrained to be r_(0.05) < 0.06 at 95% c.l., further improvements on this upper limit are hindered by polarized galactic foreground emissions and removal of gravitational lensing polarization. The 30/40 GHz receiver of the BICEP Array (BA) will deploy at the end of 2019 and will constrain the synchrotron foreground with unprecedented accuracy within the BK sky patch. We will show the design of the 30/40 GHz detectors and test results summarizing its performance. The low optical and atmospheric loading at these frequencies requires our TES detectors to have low saturation power in order to be photon noise dominated. To realize the low thermal conductivity required from a 250 mK base temperature, we developed new bolometer leg designs. We will present the relevant measured detector parameters: G, T_c, R_n, P_(sat), and spectral bands, and noise spectra. We achieved a per bolometer NEP including all noise components of 2.07×10⁻¹⁷ W/√Hz, including an anticipated photon noise level 1.54×10⁻¹⁷W/√Hz

    2022 Upgrade and Improved Low Frequency Camera Sensitivity for CMB Observation at the South Pole

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    Constraining the Galactic foregrounds with multi-frequency Cosmic Microwave Background (CMB) observations is an essential step towards ultimately reaching the sensitivity to measure primordial gravitational waves (PGWs), the sign of inflation after the Big-Bang that would be imprinted on the CMB. The BICEP Array telescope is a set of multi-frequency cameras designed to constrain the energy scale of inflation through CMB B-mode searches while also controlling the polarized galactic foregrounds. The lowest frequency BICEP Array receiver (BA1) has been observing from the South Pole since 2020 and provides 30 GHz and 40 GHz data to characterize the Galactic synchrotron in our CMB maps. In this paper, we present the design of the BA1 detectors and the full optical characterization of the camera including the on-sky performance at the South Pole. The paper also introduces the design challenges during the first observing season including the effect of out-of-band photons on detectors performance. It also describes the tests done to diagnose that effect and the new upgrade to minimize these photons, as well as installing more dichroic detectors during the 2022 deployment season to improve the BA1 sensitivity. We finally report background noise measurements of the detectors with the goal of having photon noise dominated detectors in both optical channels. BA1 achieves an improvement in mapping speed compared to the previous deployment season.Comment: Proceedings of SPIE Astronomical Telescopes + Instrumentation 2022 (AS22

    Detection of B-mode polarization at degree angular scales by BICEP2

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    We report results from the BICEP2 experiment, a cosmic microwave background (CMB) polarimeter specifically designed to search for the signal of inflationary gravitational waves in the B-mode power spectrum around ℓ∼80. The telescope comprised a 26 cm aperture all-cold refracting optical system equipped with a focal plane of 512 antenna coupled transition edge sensor 150 GHz bolometers each with temperature sensitivity of ≈300  μKCMB√s . BICEP2 observed from the South Pole for three seasons from 2010 to 2012. A low-foreground region of sky with an effective area of 380 square deg was observed to a depth of 87 nK deg in Stokes Q and U. In this paper we describe the observations, data reduction, maps, simulations, and results. We find an excess of B-mode power over the base lensed-ΛCDM expectation in the range 305σ. Through jackknife tests and simulations based on detailed calibration measurements we show that systematic contamination is much smaller than the observed excess. Cross correlating against WMAP 23 GHz maps we find that Galactic synchrotron makes a negligible contribution to the observed signal. We also examine a number of available models of polarized dust emission and find that at their default parameter values they predict power ∼(5–10)× smaller than the observed excess signal (with no significant cross-correlation with our maps). However, these models are not sufficiently constrained by external public data to exclude the possibility of dust emission bright enough to explain the entire excess signal. Cross correlating BICEP2 against 100 GHz maps from the BICEP1 experiment, the excess signal is confirmed with 3σ significance and its spectral index is found to be consistent with that of the CMB, disfavoring dust at 1.7σ. The observed B-mode power spectrum is well fit by a lensed-ΛCDM+tensor theoretical model with tensor-to-scalar ratio r=0.20 +0.07 −0.05, with r=0 disfavored at 7.0σ. Accounting for the contribution of foreground, dust will shift this value downward by an amount which will be better constrained with upcoming data sets

    Uma heurística simples e eficaz para resolver o problema do carregamento de paletes do produtor A simple and effective heuristic to solve the manufacturing pallet loading problem

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    Neste artigo apresentamos uma heurística simples e eficaz para resolver o problema do carregamento de paletes (PCP) com caixas de mesma dimensão, também chamado PCP do produtor. Basicamente, o problema consiste em como arranjar, sem sobreposição, o maior número de retângulos (l,w) dentro de um retângulo maior (L,W). Este problema também aparece no carregamento de paletes sobre carrocerias de caminhões e no projeto de embalagens para formar unidades de carga intermediárias. Aparentemente simples de ser resolvido otimamente, o PCP do produtor em geral é difícil do ponto de vista da teoria de complexidade, e diversos autores têm proposto métodos de solução aproximados. No presente artigo apresentamos um refinamento da heurística de Bischoff e Dowsland, de fácil implementação computacional e que foi capaz de obter a solução ótima de todos os exemplos aqui analisados.<br>In this paper we present a simple and effective heuristic to solve the pallet loading problem (PLP) with identical boxes, namely the manufacturer's PLP. Basically, the problem consists of arranging the maximum number of rectangles (l,w) into a larger rectangle (L,W) without overlapping. This problem also arises in the loading of pallets into trucks or rail cars, and in the design of packages which will be further combined to form a unit load. Although apparently easy to be optimally solved, the manufacturer's PLP is difficult from the perspective of the complexity theory, and several authors have proposed approximate methods to treat it. In this paper we present a refinement of Bischoff and Dowsland's heuristic which is easily implementable in a computer and provided the optimal solution of all examples here analysed
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