534 research outputs found
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Pilot-Plant Development of a Rover Waste Calcination Flowsheet
Results of eight runs, six using the 10-cm dia and two using the 30-cm dia pilot-plant calciners, in which simulated first-cycle Rover waste was calcined, are described. Results of the tests showed that a feed blend consisting of one volume simulated first-cycle Rover waste and one or two volumes simulated first-cycle zirconium waste could not be successfully calcined. 5 figs., 8 tables
The Hubble Constant determined through an inverse distance ladder including quasar time delays and Type Ia supernovae
Context. The precise determination of the present-day expansion rate of the
Universe, expressed through the Hubble constant , is one of the most
pressing challenges in modern cosmology. Assuming flat CDM,
inference at high redshift using cosmic-microwave-background data from Planck
disagrees at the 4.4 level with measurements based on the local
distance ladder made up of parallaxes, Cepheids and Type Ia supernovae (SNe
Ia), often referred to as "Hubble tension". Independent,
cosmological-model-insensitive ways to infer are of critical importance.
Aims. We apply an inverse-distance-ladder approach, combining strong-lensing
time-delay-distance measurements with SN Ia data. By themselves, SNe Ia are
merely good relative distance indicators, but by anchoring them to strong
gravitational lenses one can obtain an measurement that is relatively
insensitive to other cosmological parameters. Methods. A cosmological parameter
estimate is performed for different cosmological background models, both for
strong-lensing data alone and for the combined lensing + SNe Ia data sets.
Results. The cosmological-model dependence of strong-lensing measurements
is significantly mitigated through the inverse distance ladder. In combination
with SN Ia data, the inferred consistently lies around 73-74 km s
Mpc, regardless of the assumed cosmological background model. Our
results agree nicely with those from the local distance ladder, but there is a
>2 tension with Planck results, and a ~1.5 discrepancy with
results from an inverse distance ladder including Planck, Baryon Acoustic
Oscillations and SNe Ia. Future strong-lensing distance measurements will
reduce the uncertainties in from our inverse distance ladder.Comment: 5 pages, 3 figures, A&A letters accepted versio
TDCOSMO XI. Automated Modeling of 9 Strongly Lensed Quasars and Comparison Between Lens Modeling Software
To use strong gravitational lenses as an astrophysical or cosmological probe,
models of their mass distributions are often needed. We present a new,
time-efficient automation code for uniform modeling of strongly lensed quasars
with GLEE, a lens modeling software, for high-resolution multi-band data. By
using the observed positions of the lensed quasars and the spatially extended
surface brightness distribution of the lensed quasar host galaxy, we obtain a
model of the mass distribution of the lens galaxy. We apply this uniform
modeling pipeline to a sample of nine strongly lensed quasars with HST WFC 3
images. The models show in most cases well reconstructed light components and a
good alignment between mass and light centroids. We find that the automated
modeling code significantly reduces the user input time during the modeling
process. The preparation time of required input files is reduced significantly.
This automated modeling pipeline can efficiently produce uniform models of
extensive lens system samples which can be used for further cosmological
analysis. A blind test through a comparison with the results of an independent
automated modeling pipeline based on the modeling software Lenstronomy reveals
important lessons. Quantities such as Einstein radius, astrometry, mass
flattening and position angle are generally robustly determined. Other
quantities depend crucially on the quality of the data and the accuracy of the
PSF reconstruction. Better data and/or more detailed analysis will be necessary
to elevate our automated models to cosmography grade. Nevertheless, our
pipeline enables the quick selection of lenses for follow-up monitoring and
further modeling, significantly speeding up the construction of
cosmography-grade models. This is an important step forward to take advantage
of the orders of magnitude increase in the number of lenses expected in the
coming decade.Comment: 36 pages, 13 figures, submitted to A&
STRIDES: a 3.9 per cent measurement of the Hubble constant from the strong lens system DES J0408-5354
We present a blind time-delay cosmographic analysis for the lens system DES J0408-5354. This system is extraordinary for the presence of two sets of multiple images at different redshifts, which provide the opportunity to obtain more information at the cost of increased modelling complexity with respect to previously analysed systems. We perform detailed modelling of the mass distribution for this lens system using three band Hubble Space Telescope imaging. We combine the measured time delays, line-of-sight central velocity dispersion of the deflector, and statistically constrained external convergence with our lens models to estimate two cosmological distances. We measure the 'effective' time-delay distance corresponding to the redshifts of the deflector and the lensed quasar DΔ t eff=3382-115+146 Mpc and the angular diameter distance to the deflector Dd = 1711-280+376 Mpc, with covariance between the two distances. From these constraints on the cosmological distances, we infer the Hubble constant H0= 74.2-3.0+2.7 km s-1 Mpc-1 assuming a flat ΛCDM cosmology and a uniform prior for ωm as \Omega m ∼ \mathcal {U(0.05, 0.5). This measurement gives the most precise constraint on H0 to date from a single lens. Our measurement is consistent with that obtained from the previous sample of six lenses analysed by the H0 Lenses in COSMOGRAIL's Wellspring (H0LiCOW) collaboration. It is also consistent with measurements of H0 based on the local distance ladder, reinforcing the tension with the inference from early Universe probes, for example, with 2.2σ discrepancy from the cosmic microwave background measurement. © 2020 The Author(s) Published by Oxford University Press on behalf of the Royal Astronomical Society
Sio: A spatioimageomics pipeline to identify prognostic biomarkers associated with the ovarian tumor microenvironment
Stromal and immune cells in the tumor microenvironment (TME) have been shown to directly affect high-grade serous ovarian cancer (HGSC) malignant phenotypes, however, how these cells interact to influence HGSC patients’ survival remains largely unknown. To investigate the cell-cell communication in such a complex TME, we developed a SpatioImageOmics (SIO) pipeline that combines imaging mass cytometry (IMC), location-specific transcriptomics, and deep learning to identify the distribution of various stromal, tumor and immune cells as well as their spatial relationship in TME. The SIO pipeline automatically and accurately segments cells and extracts salient cellular features to identify biomarkers, and multiple nearest-neighbor interactions among tumor, immune, and stromal cells that coordinate to influence overall survival rates in HGSC patients. In addition, SIO integrates IMC data with microdissected tumor and stromal transcriptomes from the same patients to identify novel signaling networks, which would lead to the discovery of novel survival rate-modulating mechanisms in HGSC patients
Immunomodulation by α(1)-proteinase inhibitor: lack of chemotactic effects of recombinant human α(1)-proteinase inhibitor from yeast on human peripheral blood granulocytes
The ellipticity parameterization for an NFW profile: An overlooked angular structure in strong lens modeling
peer reviewedGalaxy-scale gravitational lenses are often modeled with two-component mass profiles where one component represents the stellar mass and the second is an NFW profile representing the dark matter. Outside of the spherical case, the NFW profile is costly to implement, and so it is approximated via two different methods; ellipticity can be introduced via the lensing potential (NFWp) or via the mass by approximating the NFW profile as a sum of analytical profiles (NFWm). While the NFWp method has been the default for lensing applications, it gives a different prescription of the azimuthal structure, which we show introduces ubiquitous gradients in ellipticity and boxiness in the mass distribution rather than having a constant elliptical shape. Because unmodeled azimuthal structure has been shown to be able to bias lens model results, we explore the degree to which this introduced azimuthal structure can affect the model accuracy. We construct input profiles using composite models using both the NFWp and NFWm methods and fit these mocks with a power-law elliptical mass distribution (PEMD) model with external shear. As a measure of the accuracy of the recovered lensing potential, we calculate the value of the Hubble parameter one would determine from the lensing fit. We find that the fits to the NFWp input return values which are systematically biased by about lower than the NFWm counterparts. We explore whether such an effect is attributable to the mass sheet transformation (MST) by using an MST-independent quantity, . We show that, as expected, the NFWm mocks are degenerate with PEMD through an MST. For the NFWp, an additional bias is found beyond the MST due to azimuthal structures {\it exterior to the Einstein radius}. We recommend modelers use an NFWm prescription in the future, such that azimuthal structure can be introduced explicitly rather than implicitly
SkyPy: A package for modelling the Universe
SkyPy is an open-source Python package for simulating the astrophysical sky. It comprises
a library of physical and empirical models across a range of observables and a command line
script to run end-to-end simulations. The library provides functions that sample realisations
of sources and their associated properties from probability distributions. Simulation pipelines
are constructed from these models using a YAML-based configuration syntax, while task
scheduling and data dependencies are handled internally and the modular design allows users
to interface with external software. SkyPy is developed and maintained by a diverse community
of domain experts with a focus on software sustainability and interoperability. By fostering
co-development, it provides a framework for correlated simulations of a range of cosmological
probes including galaxy populations, large scale structure, the cosmic microwave background,
supernovae and gravitational waves.
Version 0.4 implements functions that model various properties of galaxies including luminosity functions, redshift distributions and optical photometry from spectral energy distribution
templates. Future releases will provide additional modules, for example to simulate populations of dark matter halos and model the galaxy-halo connection, making use of existing
software packages from the astrophysics community where appropriate
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H0LiCOW X: Spectroscopic/imaging survey and galaxy-group identification around the strong gravitational lens system WFI2033-4723
Galaxies and galaxy groups located along the line of sight towards
gravitationally lensed quasars produce high-order perturbations of the
gravitational potential at the lens position. When these perturbation are too
large, they can induce a systematic error on of a few-percent if the lens
system is used for cosmological inference and the perturbers are not explicitly
accounted for in the lens model. In this work, we present a detailed
characterization of the environment of the lens system WFI2033-4723 (, = 0.6575), one of the core targets of the H0LICOW
project for which we present cosmological inferences in a companion paper (Rusu
et al. 2019). We use the Gemini and ESO-Very Large telescopes to measure the
spectroscopic redshifts of the brightest galaxies towards the lens, and use the
ESO-MUSE integral field spectrograph to measure the velocity-dispersion of the
lens ( km/s) and of several nearby
galaxies. In addition, we measure photometric redshifts and stellar masses of
all galaxies down to mag, mainly based on Dark Energy Survey imaging
(DR1). Our new catalog, complemented with literature data, more than doubles
the number of known galaxy spectroscopic redshifts in the direct vicinity of
the lens, expanding to 116 (64) the number of spectroscopic redshifts for
galaxies separated by less than 3 arcmin (2 arcmin) from the lens. Using the
flexion-shift as a measure of the amplitude of the gravitational perturbation,
we identify 2 galaxy groups and 3 galaxies that require specific attention in
the lens models. The ESO MUSE data enable us to measure the
velocity-dispersions of three of these galaxies. These results are essential
for the cosmological inference analysis presented in Rusu et al. (2019).Comment: Matches the version accepted for publication by MNRAS. Note that this
paper previously appeared as H0LICOW X
Gas Accretion and Galactic Chemical Evolution: Theory and Observations
This chapter reviews how galactic inflows influence galaxy metallicity. The
goal is to discuss predictions from theoretical models, but particular emphasis
is placed on the insights that result from using models to interpret
observations. Even as the classical G-dwarf problem endures in the latest round
of observational confirmation, a rich and tantalizing new phenomenology of
relationships between , , SFR, and gas fraction is emerging both in
observations and in theoretical models. A consensus interpretation is emerging
in which star-forming galaxies do most of their growing in a quiescent way that
balances gas inflows and gas processing, and metal dilution with enrichment.
Models that explicitly invoke this idea via equilibrium conditions can be used
to infer inflow rates from observations, while models that do not assume
equilibrium growth tend to recover it self-consistently. Mergers are an overall
subdominant mechanism for delivering fresh gas to galaxies, but they trigger
radial flows of previously-accreted gas that flatten radial gas-phase
metallicity gradients and temporarily suppress central metallicities. Radial
gradients are generically expected to be steep at early times and then
flattened by mergers and enriched inflows of recycled gas at late times.
However, further theoretical work is required in order to understand how to
interpret observations. Likewise, more observational work is needed in order to
understand how metallicity gradients evolve to high redshifts.Comment: Invited review to appear in Gas Accretion onto Galaxies, Astrophysics
and Space Science Library, eds. A. J. Fox & R. Dav\'e, to be published by
Springer. 29 pages, 2 figure
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