Chirality induced anomalous-Hall effect in helical spin crystals

Under pressure, the itinerant helimagnet MnSi displays unusual magnetic properties. We have previously discussed a BCC helical spin crystal as a promising starting point for describing the high pressure phenomenology. This state has topologically nontrivial configurations of the magnetization field. Here we note the consequences for magneto-transport that arise generally from such spin textures. In particular a skyrmion density induced `topological' Hall effect, with unusual field dependence, is described.Comment: 4 pages, 3 figures, to appear in the proceedings of SCES 07 (the international conference on strongly correlated electron systems 2007 in Houston, USA

Skyrmion Lattice in a Chiral Magnet

Skyrmions represent topologically stable field configurations with particle-like properties. We used neutron scattering to observe the spontaneous formation of a two-dimensional lattice of skyrmion lines, a type of magnetic vortices, in the chiral itinerant-electron magnet MnSi. The skyrmion lattice stabilizes at the border between paramagnetism and long-range helimagnetic order perpendicular to a small applied magnetic field regardless of the direction of the magnetic field relative to the atomic lattice. Our study experimentally establishes magnetic materials lacking inversion symmetry as an arena for new forms of crystalline order composed of topologically stable spin states

Magnetic domain formation in itinerant metamagnets

We examine the effects of long-range dipolar forces on metamagnetic transitions and generalize the theory of Condon domains to the case of an itinerant electron system undergoing a first-order metamagnetic transition. We demonstrate that within a finite range of the applied field, dipolar interactions induce a spatial modulation of the magnetization in the form of stripes or bubbles. Our findings are consistent with recent observations in the bilayer ruthenate Sr$_3$Ru$_2$O$_7$.Comment: 4 pages, 3 figures, minor changes, references adde

Phonon-mediated tuning of instabilities in the Hubbard model at half-filling

We obtain the phase diagram of the half-filled two-dimensional Hubbard model on a square lattice in the presence of Einstein phonons. We find that the interplay between the instantaneous electron-electron repulsion and electron-phonon interaction leads to new phases. In particular, a d$_{x^2-y^2}$-wave superconducting phase emerges when both anisotropic phonons and repulsive Hubbard interaction are present. For large electron-phonon couplings, charge-density-wave and s-wave superconducting regions also appear in the phase diagram, and the widths of these regions are strongly dependent on the phonon frequency, indicating that retardation effects play an important role. Since at half-filling the Fermi surface is nested, spin-density-wave is recovered when the repulsive interaction dominates. We employ a functional multiscale renormalization-group method that includes both electron-electron and electron-phonon interactions, and take retardation effects fully into account.Comment: 8 pages, 5 figure

The Most Severe Test for Hydrophobicity Scales: Two Proteins with 88% Sequence Identity but Different Structure and Function

Protein-protein interactions (protein functionalities) are mediated by water, which compacts individual proteins and promotes close and temporarily stable large-area protein-protein interfaces. In their classic paper Kyte and Doolittle (KD) concluded that the "simplicity and graphic nature of hydrophobicity scales make them very useful tools for the evaluation of protein structures". In practice, however, attempts to develop hydrophobicity scales (for example, compatible with classical force fields (CFF) in calculating the energetics of protein folding) have encountered many difficulties. Here we suggest an entirely different approach, based on the idea that proteins are self-organized networks, subject to finite-scale criticality (like some network glasses). We test this proposal against two small proteins that are delicately balanced between alpha and alpha/beta structures, with different functions encoded with only 12% of their amino acids. This example explains why protein structure prediction is so challenging, and it provides a severe test for the accuracy and content of hydrophobicity scales. The new method confirms KD's evaluation, and at the same time suggests that protein structure, dynamics and function can be best discussed without using CFF

Solution of the infinite range t-J model

The t-J model with constant t and J between any pair of sites is studied by exploiting the symmetry of the Hamiltonian with respect to site permutations. For a given number of electrons and a given total spin the exchange term simply yields an additive constant. Therefore the real problem is to diagonalize the "t- model", or equivalently the infinite U Hubbard Hamiltonian. Using extensively the properties of the permutation group, we are able to find explicitly both the energy eigenvalues and eigenstates, labeled according to spin quantum numbers and Young diagrams. As a corollary we also obtain the degenerate ground states of the finite $U$ Hubbard model with infinite range hopping -t>0.Comment: 15 pages, 2 figure

Topological Hall effect in the A-phase of MnSi

Recent small angle neutron scattering suggests, that the spin structure in the A-phase of MnSi is a so-called triple-$Q$ state, i.e., a superposition of three helices under 120 degrees. Model calculations suggest that this structure in fact is a lattice of so-called skyrmions, i.e., a lattice of topologically stable knots in the spin structure. We report a distinct additional contribution to the Hall effect in the temperature and magnetic field range of the proposed skyrmion lattice, where such a contribution is neither seen nor expected for a normal helical state. Our Hall effect measurements constitute a direct observation of a topologically quantized Berry phase that identifies the spin structure seen in neutron scattering as the proposed skyrmion lattice

spl(2,1) dynamical supersymmetry and suppression of ferromagnetism in flat band double-exchange models

The low energy spectrum of the ferromagnetic Kondo lattice model on a N-site complete graph extended with on-site repulsion is obtained from the underlying spl(2,1) algebra properties in the strong coupling limit. The ferromagnetic ground state is realized for 1 and N+1 electrons only. We identify the large density of states to be responsible for the suppression of the ferromagnetic state and argue that a similar situation is encountered in the Kagome, pyrochlore, and other lattices with flat bands in their one-particle density of states.Comment: 7 pages, 1 figur

Botulinum neurotoxin type C protease induces apoptosis in differentiated human neuroblastoma cells

Neuroblastomas constitute a major cause of cancer-related deaths in young children. In recent years, a number of translation-inhibiting enzymes have been evaluated for killing neuroblastoma cells. Here we investigated the potential vulnerability of human neuroblastoma cells to protease activity derived from botulinum neurotoxin type C. We show that following retinoic acid treatment, human neuroblastoma cells, SiMa and SH-SY5Y, acquire a neuronal phenotype evidenced by axonal growth and expression of neuronal markers. Botulinum neurotoxin type C which cleaves neuron-specific SNAP25 and syntaxin1 caused apoptotic death only in differentiated neuroblastoma cells. Direct comparison of translation-inhibiting enzymes and the type C botulinum protease revealed one order higher cytotoxic potency of the latter suggesting a novel neuroblastoma-targeting pathway. Our mechanistic insights revealed that loss of ubiquitous SNAP23 due to differentiation coupled to SNAP25 cleavage due to botulinum activity may underlie the apoptotic death of human neuroblastoma cells