Titan Mare Explorer (TiME): first in situ exploration of an extraterrestrial sea

The lakes and seas of Titan are a sink of products of photolysis in the atmosphere, and a crucial component in Titan's active methane cycle. In situ exploration of the seas is necessary to understand their intriguing prebiotic organic chemistry

MP3 - A meteorology and physical properties package to explore air-sea interaction on Titan

The exchange of mass, heat and momentum at the air:sea interface are profound influences on the terrestrial environment, affecting the intensity of hurricanes, the size of waves and lake-effect precipitation. Titan presents us with an opportunity to study these processes in a novel physical context, with a different sea, atmosphere and gravity. The MP3 instrument, under development for the proposed Discovery mission TiME (Titan Mare Explorer [1,2]) is an integrated suite of small, simple sensors that combines the function of traditional meteorology packages with liquid physical properties and depth-sounding : these latter functions follow the concept of - and indeed use spare elements from - the Huygens Surface Science Package (SSP,[3]). However, unlike Huygens’ brief and dynamic 3 hours of measurement, in TiME’s 6-Titan-day (96 Earth day) nominal mission enabled by radioisotope power, MP3 will have an unprecedented long-term measurement opportunity in one of the most evocative environments in the solar system, Titan’s sea Ligeia Mare

Hemispherical differences in the shape and topography of asteroid (101955) Bennu

We investigate the shape of near-Earth asteroid (101955) Bennu by constructing a high-resolution (20 cm) global digital terrain model from laser altimeter data. By modeling the northern and southern hemispheres separately, we find that longitudinal ridges previously identified in the north extend into the south but are obscured there by surface material. In the south, more numerous large boulders effectively retain surface materials and imply a higher average strength at depth to support them. The north has fewer large boulders and more evidence of boulder dynamics (toppling and downslope movement) and surface flow. These factors result in Bennu’s southern hemisphere being rounder and smoother, whereas its northern hemisphere has higher slopes and a less regular shape. We infer an originally asymmetric distribution of large boulders followed by a partial disruption, leading to wedge formation in Bennu’s history

Accumulation of advanced glycation end (AGEs) products in intensive care patients: an observational, prospective study

<p>Abstract</p> <p>Background</p> <p>Oxidative stress plays an important role in the course and eventual outcome in a majority of patients admitted to the intensive care unit (ICU). Markers to estimate oxidative stress are not readily available in a clinical setting. AGEs accumulation has been merely described in chronic conditions, but can also occur acutely due to oxidative stress. Since AGEs have emerged to be stable end products, these can be a marker of oxidative stress. Skin autofluorescence (AF) is a validated marker of tissue content of AGEs. We hypothesized that AGEs accumulate acutely in ICU patients.</p> <p>Methods</p> <p>We performed an observational prospective study in a medical surgical ICU in a university affiliated teaching hospital. All consecutively admitted ICU patients in a 2 month period were included. Skin AF was measured using an AGE reader in 35 consecutive ICU patients > 18 yrs. As a comparison, historical data of a control group (n = 231) were used. These were also used to calculate age-adjusted AF-levels (AF_adj). Values are expressed as median and interquartile range [P₂₅-P₇₅]. Differences between groups were tested by non parametric tests. P < 0.05 was considered statistically significant.</p> <p>Results</p> <p>AF_adjvalues were higher in ICU patients (0.33 [0.00 - 0.68]) than in controls (-0.07 [-0.29 - 0.24]; P < 0.001). No differences in skin AF_adjwere observed between acute or planned admissions, or presence of sepsis, nor was skin AF_adjrelated to severity of disease as estimated by APACHE-II score, length of ICU, hospital stay or mortality.</p> <p>Conclusion</p> <p>Acute AGE accumulation in ICU patients was shown in this study, although group size was small. This can possibly reflect oxidative stress in ICU patients. Further studies should reveal whether AGE-accumulation will be a useful parameter in ICU patients and whether skin AF has a predictive value for outcome, which was not shown in this small study.</p

Bennu regolith mobilized by TAGSAM: Expectations for the OSIRIS-REx sample collection event and application to understanding naturally ejected particles

The Origins, Spectral Interpretation, Resource Identification, and Security–Regolith Explorer (OSIRIS-REx) mission will collect material from the asteroid Bennu and return it to Earth. The sample collection method uses pressurized nitrogen gas to mobilize regolith. It is likely that the gas will mobilize more, potentially much more, material than is captured by the Touch-and-Go Sample Acquisition Mechanism (TAGSAM) for return. The amount, velocities, and fate of this mobilized material have important implications for our understanding of Bennu's physical properties and processes, such as impact cratering, regolith mobility, and the recently observed natural ejection of particles. The nature of the TAGSAM-ejected material is also significant for mission operations. We conducted numerical simulations and ground-based tests to estimate the amount and speeds of material mobilized by the sampling event. The estimated ejected masses range from 12 kg to >165 kg; given that Bennu appears to be a nearly strengthless rubble pile, the higher end of the mass range is more likely. Maximum ejection speeds for 1-cm-diameter particles could reach 10 m/s; smaller particles will be ejected at faster speeds. Minimum ejection speeds will be determined by the as yet unknown cohesive strength of Bennu's regolith. Material ejected more slowly than 10 cm/s will reaccrete on Bennu; material ejected between 10 and 30 cm/s may or may not reaccrete; and material ejected faster than 30 cm/s will escape. Some of the ejected material is predicted to remain in transient orbits around Bennu. The lifetimes of these orbits span from days to several weeks, the maximum duration of our integrations. Reaccreted material should be concentrated in a region near the sample site, although re-impacts will occur globally. Gas from TAGSAM will mobilize material beyond the contact perimeter; because of interactions between cohesion and microgravity, there is a preferred particle size of mobility, predicted to be tens of centimeters, depending on the TAG latitude. Observing Bennu during and after the sampling event will make it possible to test these predictions and understand how the asteroid responds to disruption and particle mobility across the surface

Craters, Boulders and Regolith of (101955) Bennu Indicative of an Old and Dynamic Surface

Small, kilometre-sized near-Earth asteroids are expected to have young and frequently refreshed surfaces for two reasons: collisional disruptions are frequent in the main asteroid belt where they originate, and thermal or tidal processes act on them once they become near-Earth asteroids. Here we present early measurements of numerous large candidate impact craters on near-Earth asteroid (101955) Bennu by the OSIRIS-REx (Origins, Spectral Interpretation, Resource Identification, and Security- Regolith Explorer) mission, which indicate a surface that is between 100 million and 1 billion years old, predating Bennu's expected duration as a near-Earth asteroid. We also observe many fractured boulders, the morphology of which suggests an influence of impact or thermal processes over a considerable amount of time since the boulders were exposed at the surface. However, the surface also shows signs of more recent mass movement: clusters of boulders at topographic lows, a deficiency of small craters and infill of large craters. The oldest features likely record events from Bennu's time in the main asteroid belt