Dysfunkcje rodziny, a piecza zastępcza

In the article, the issues concerning child welfare, family dysfunctions and foster care in Polish legal system are discussed. The thesis characterizes the importance of the family, its functions and the role in the life of each child. The problem of family dysfunctions, improper attitudes and parental behaviours is disclosed. Moreover, the foster care institution is presented as a form of family support applied in the absence of due parental care and violation of the child welfare principle.W artykule zostały omówione zagadnienia dobra dziecka, dysfunkcji rodziny oraz pieczy zastępczej w polskim systemie prawnym. W pracy opisano znaczenie rodziny, jej funkcji oraz roli w życiu każdego dziecka. Przybliżono problem dysfunkcji rodziny, niewłaściwych postaw i zachowań rodzicielskich. Ponadto przedstawiono instytucję pieczy zastępczej jako formę pomocy rodzinie stosowaną w przypadku braku należytej pieczy rodzicielskiej oraz naruszenia zasady dobra dziecka

Liposuction in the treatment of idiopathic lower extremity lymphoedema

Idiopatyczny obrzęk limfatyczny kończyn dolnych jest dość rzadką chorobą o nieznanej etiologii. Wśród prawdopodobnych czynników wywołujących go wyróżnia się infekcję, predyspozycje genetyczne, malformacje naczyń limfatycznych. Diagnozę potwierdza zwykle obserwacja kliniczna, jednak powinno się ją zweryfikować, przeprowadzając limfoscyntygrafię. Rekomendowana przez Międzynarodowe Towarzystwo Limfologiczne terapia zwana kompleksową terapią przeciwzastoinową (CTD) obejmuje ręczny drenaż limfatyczny, bandażowanie uciskowe z zastosowaniem bandaży o małej elastyczności i ćwiczenia przeciwzastoinowe. Kompleksowa terapia przeciwzastoinowa daje dobre efekty terapeutyczne, potwierdzone badaniami klinicznymi. Jednak w niektórych przypadkach niemożliwe jest osiągniecie jakiejkolwiek redukcji obrzęku lub uzyskany rezultat jest niewielki. W obrzęku limfatycznym niepoddającym się leczeniu za pomocą terapii kompresyjnej bezpieczną i skuteczną metodą okazała się liposukcja, wprowadzona do leczenia obrzęku przez Brorsona. W poniższym artykule przedstawiono przypadek obrzęku limfatycznego kończyny dolnej leczony za pomocą liposukcji w ośrodku autorów pracy. Acta Angiol 2011; 17, 4: 271–276Idiopathic lymphoedema of the lower extremities is an uncommon disease of unknown aetiology. Possible pathogenic factors include infection, genetic predisposition, and lymphatic vascular malformations. Diagnosis is usually based upon clinical presentation; however, it should be confirmed by lymphoscintigraphy. Standard treatment, recommended by the International Society of Lymphology, called complex decongestive therapy (CDT) includes manual lymphatic drainage, compression therapy using low-stretch bandages, and decongestive exercises. CDT is an effective treatment which is proven in clinical studies; however, in some cases only limited or no oedema reduction can be achieved. Liposuction, introduced to lymphoedema therapy by Brorson, has been proven to be a safe and effective treatment in lymphoedema not responding to compression therapy. We present a case of idiopathic lower extremity lymphoedema treated with liposuction in our centre. Acta Angiol 2011; 17, 4: 271–27

Arsenic (As) and breast cancer risk

The study was conducted to determine the correlations between serum concentration of arsenic (As) with increased or decreased predisposition to breast and ovarian cancer

Geoproduct potential analysis based on the example of the GEOsfera Ecological and Geological Education Center in Jaworzno

At the time of discovering and exposing the scientific and educational potential of areas where mineral resources were exploited in the past, they have become a significant element in tourism elements. In the presented paper, the potential of the GEOsfera Ecological and Geological Education Centre in Jaworzno as a geoproduct was analysed. In the first part of the study, based on the published works and consultations with experts, the “geoproduct” was defined. Then the area, where the GEOsphere is located, was characterized. Its geology, the natural world, the way of land development and the promotion of geo-attractions located in this area are described. In the next stage, an analysis of the opinions of users regarding their perception of the GEOsphere was carried out. For this purpose, evaluations posted on social media and the collected survey results were used. As shown by the results, the majority of users of the GEOsfera are residents of Jaworzno – 63% of the respondents. The importance of the GEOsphere as an educational centre was indicated by 22% of visitors. About 5% of the respondents mentioned learning and obtaining information from the descriptions placed next to the exhibits in the centre. 93% of respondents recognised the graduation tower as the greatest attraction of the GEOsphere. Over 92% of people noticed the recreational role of the GEOsphere. 81% of users declared that they were satisfied with their visit to the GEOsphere. More than half of the respondents (56%) visited the GEOsfera with their family. A significant part of respondents (42%), pointed to the role of environmental protection, which is extremely important from the point of view of geoproducts’ design. The respondents also indicated that the GEOsphere has numerous geological, natural and educational functions and protects and promotes the geological heritage of the region

ACE and ACE2 expression in normal and malignant skin lesions

 The renin-angiotensin system (RAS) is known mainly as a regulator of cardiovascular homeostasis. However, it has also been shown to mediate processes such as proliferation, apoptosis, angiogenesis, and carcinogenesis. Nonmelanoma skin cancers (NMSC) — including basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) — are among the most common cancers. The aim of the present study was to determine the immunohistochemical expression of angiotensin-converting enzyme (ACE), angiotensin-converting enzyme 2 (ACE2), and Ki-67 antigen in archival samples of normal skin, actinic keratosis, and malignant skin lesions. Cytoplasmic-nuclear ACE immunoreactivity was observed in 99% of examined cases of both normal skin and cancers. Significantly higher ACE immunoreactivity occurred in normal skin, as compared with BCC and SCC (p < 0.01, p < 0.0001, respectively). Additionally, ACE immunoreactivity was also significantly higher in BCC, compared with SCC (p < 0.05). ACE2 immunoreactivity was noted in basal epidermal layers and in sebaceous gland cells in normal skin, though not in NMSC. These novel observations suggest that ACE and skin RAS may be involved in the pathogenesis of malignant skin lesions.

Geoproduct potential analysis based on the example of the GEOsfera Ecological and Geological Education Center in Jaworzno

At the time of discovering and exposing the scientific and educational potential of areas where mineral resources were exploited in the past, they have become a significant element in tourism elements. In the presented paper, the potential of the GEOsfera Ecological and Geological Education Centre in Jaworzno as a geoproduct was analysed. In the first part of the study, based on the published works and consultations with experts, the “geoproduct” was defined. Then the area, where the GEOsphere is located, was characterized. Its geology, the natural world, the way of land development and the promotion of geo-attractions located in this area are described. In the next stage, an analysis of the opinions of users regarding their perception of the GEOsphere was carried out. For this purpose, evaluations posted on social media and the collected survey results were used. As shown by the results, the majority of users of the GEOsfera are residents of Jaworzno – 63% of the respondents. The importance of the GEOsphere as an educational centre was indicated by 22% of visitors. About 5% of the respondents mentioned learning and obtaining information from the descriptions placed next to the exhibits in the centre. 93% of respondents recognised the graduation tower as the greatest attraction of the GEOsphere. Over 92% of people noticed the recreational role of the GEOsphere. 81% of users declared that they were satisfied with their visit to the GEOsphere. More than half of the respondents (56%) visited the GEOsfera with their family. A significant part of respondents (42%), pointed to the role of environmental protection, which is extremely important from the point of view of geoproducts’ design. The respondents also indicated that the GEOsphere has numerous geological, natural and educational functions and protects and promotes the geological heritage of the region. W dobie odkrywania i eksponowania potencjału naukowego i edukacyjnego terenów, na których w przeszłości prowadzono eksploatację surowców, stają się one znaczącymi obiektami turystycznymi. W prezentowanej pracy dokonano analizy potencjału Centrum Edukacji Ekologiczno-Geologicznej GEOsfera w Jaworznie, zlokalizowanego na terenie wyrobiska surowców skalnych, jako geoproduktu. W pierwszej części opracowania, opierając się na dostępnych pracach publikowanych i konsultacjach z ekspertami, zdefiniowano „geoprodukt” oraz określono kryteria, jakie powinien spełniać. Następnie opisano teren, na którym zlokalizowana jest GEOsfera, uwzględniając geologię, elementy przyrody ożywionej oraz sposób zagospodarowania terenu i promowania geoatrakcji, które się tam znajdują. Na kolejnym etapie przeprowadzono analizę opinii użytkowników w zakresie postrzegania przez nich GEOsfery. Do tego celu wykorzystano oceny zamieszczone w mediach społecznościowych i zgromadzone wyniki badań ankietowych. Wykazały one, że większość spośród badanych użytkowników GEOsfery to mieszkańcy Jaworzna, którzy stanowili 63% ankietowanych. Znaczenie GEOsfery jako istotnego ośrodka edukacyjnego wskazało 22% odwiedzających. Około 5% pytanych doceniło uczenie się i pozyskiwanie informacji z opisów umieszczonych na tablicach obok eksponatów na terenie ośrodka. Jako największą atrakcję terenu GEOsfery 93% ankietowanych wskazało tężnię solankową. Ponad 92% respondentów dostrzegło rekreacyjną rolę GEOsfery i dogodne warunki do aktywnego spędzania czasu. 81% badanych zadeklarowało zadowolenie z wizyty. Ponad połowa respondentów (56%) odwiedziła GEOsferę z rodziną. Znaczna część ankietowanych (42%) zwróciła uwagę na znaczenie ochrony środowiska w funkcjonowaniu GEOsfery, co jest niezwykle ważną informacją przydatną podczas projektowania geoproduktu. Użytkownicy, którzy wzięli udział w badaniu, wskazali również, że GEOsfera ma liczne walory geologiczne, przyrodnicze i edukacyjne oraz chroni i promuje dziedzictwo geologiczne regionu

Varied effect of fortification of kale sprouts with novel organic selenium compounds on the synthesis of sulphur and phenolic compounds in relation to cytotoxic, antioxidant and anti-inflammatory activity

Selenium deficiency in daily diet is a common problem in many countries, thus searching for new dietary sources of this trace element is an important scientific challenge. Selenium biofortified sprouts from Brassicaceae family are good candidates for new dietary selenium source, as they reveal one of the highest capability to synthesize and accumulate this element. As a part of this extensive search, the influence of novel selenium organic compounds on fortification of kale sprouts biological activity was investigated. The present study is focused on the evaluation of the influence of these compounds on the synthesis of glucosinolates, isothiocyanates, indoles and phenolic acids in kale sprouts, together with the determination of their impact on antioxidant, anti-inflammatory and cytotoxic activity on gastrointestinal, prostate, and thyroid normal and cancer cells. The present study yields the conclusion that fortification of kale sprouts with selenium organic compounds bearing benzoselenoate scaffold influences the production of isothiocyanates, phenolic acids, and enhances the antioxidant properties of fortified sprouts. Notably, fortification with compounds based on benzoselenoate scaffold display chemoprotective properties in various cancer types (gastric, thyroid, and prostate cancer). The present study can facilitate the design of future agrochemicals. Compounds bearing benzoselenoate scaffold or selenyl phenylpiperazine motif seem to be particularly promising for these purposes.This study was partly supported by Polish grants N42/DBS/000231 and N42/DBS/000167. The publication was created with the use of equipment’s (Biotek Synergy microplate reader and Dionex HPLC system) co-financed by the qLIFE Priority Research Area under the program “Excellence Initiative—Research University” (No. 06/IDUB/2019/94) at Jagiellonian University

Postoperative functioning of cardiac patients. Diagnostic methods of postoperative monitoring and risk of mortality

Abstract Introduction: Cardiovascular diseases are the most common reason for deaths of people. Progress in cardiac surgery and cardiac diagnosis a significantly decreased the risk of surgery and postoperative mortality in patients. The aim of our study was to present methods for monitoring patients after cardiac surgery and to assess the risk of morality. Material and methods: Articles in the EBSCO database have been analysed using keywords: postoperative functioning, cardiac surgery, risk of morality. Results: Studies have shown that cardiac surgery patients are a large group with many co-existing health problems that affect the occurrence of problems in the postoperative period. Hemodynamic monitoring of patients is carried out using a variety of techniques, both invasive and non-invasive. There are also many tools to assess post operative cognitive dysfunction. Interesting are modern methods of hemodynamic monitoring, which can be used by patients at home, after leaving the hospital. It should be remembered that all methods of treatment and monitoring of cardiac surgery patients have an impact on their quality of life and functioning. Do not forget about non-pharmacological methods of affecting the functioning of postoperative patients included in the ERAS protocol. Conclusions: Cardiac patients require a complex and interdisciplinary approach in the postoperative period. Many elements should be taken into account and prepared the patient for this situation. Progress in medicine more often reduces the risk of morality cardiac patients. However, should remember about the impact of all our activities on the quality of life and functioning of patients. Keywords: postoperative functioning, cardiac surgery, risk of morality Introduction Cardiovascular diseases are causing more than 17 million deaths worldwide, and according to the World Health Organization (WHO) mortality due to cardiovascular diseases will become the leading cause of deaths of up to 20 million people per year [1]. Progress achieved in cardiac surgery and cardiac diagnosis allows for a significant reduction in the risk of surgery and postoperative mortality in patients. However, the evaluation of the result of the operation should not focus only on the effectiveness of the surgery itself. Treatment of cardiac surgery patients should also take into account how will they function in everyday life situations after the surgery