773 research outputs found
Analysis of heavy spin--3/2 baryon--heavy spin--1/2 baryon--light vector meson vertices in QCD
The heavy spin--3/2 baryon--heavy spin--1/2 baryon vertices with light vector
mesons are studied within the light cone QCD sum rules method. These vertices
are parametrized in terms of three coupling constants. These couplings are
calculated for all possible transitions. It is shown that correlation functions
for these transitions are described by only one invariant function for every
Lorenz structure. The obtained relations between the correlation functions of
the different transitions are structure independent while explicit expressions
of invariant functions depend on the Lorenz structure.Comment: 17 Pages, 6 Figures and 4 Table
The 4 K outer cryostat for the CUORE experiment: construction and quality control
The external shell of the CUORE cryostat is a large cryogen-free system
designed to host the dilution refrigerator and the bolometers of the CUORE
experiment in a low radioactivity environment. The three vessels that form the
outer shell were produced and delivered to the Gran Sasso underground
Laboratories in July 2012. In this paper, we describe the production techniques
and the validation tests done at the production site in 2012.Comment: 11 pages, 13 figures; to appear in NIM
Searches for axioelectric effect of solar axions with BGO-scintillator and BGO-bolometer detectors
A search for axioelectric absorption of 5.5 MeV solar axions produced in the
reaction has been
performed with a BGO detectors. A model-independent limit on the product of
axion-nucleon and axion-electron coupling constants has
been obtained: for 90\% C.L..Comment: 5 pages, 3 figures, Proceedings of the 10th Patras Workshop on
Axions, WIMPs and WISP 29 June - 4 July 2014, CERN, Geneva, Switzerlan
The CUORE Cryostat: A 1-Ton Scale Setup for Bolometric Detectors
The cryogenic underground observatory for rare events (CUORE) is a 1-ton
scale bolometric experiment whose detector consists of an array of 988 TeO2
crystals arranged in a cylindrical compact structure of 19 towers. This will be
the largest bolometric mass ever operated. The experiment will work at a
temperature around or below 10 mK. CUORE cryostat consists of a cryogen-free
system based on pulse tubes and a custom high power dilution refrigerator,
designed to match these specifications. The cryostat has been commissioned in
2014 at the Gran Sasso National Laboratories and reached a record temperature
of 6 mK on a cubic meter scale. In this paper, we present results of CUORE
commissioning runs. Details on the thermal characteristics and cryogenic
performances of the system will be also given.Comment: 7 pages, 2 figures, LTD16 conference proceedin
First array of enriched ZnSe bolometers to search for double beta decay
The R&D activity performed during the last years proved the potential of ZnSe
scintillating bolometers to the search for neutrino-less double beta decay,
motivating the realization of the first large-mass experiment based on this
technology: CUPID-0. The isotopic enrichment in Se, the ZnSe
crystals growth, as well as the light detectors production have been
accomplished, and the experiment is now in construction at Laboratori Nazionali
del Gran Sasso (Italy). In this paper we present the results obtained testing
the first three ZnSe crystals operated as scintillating bolometers, and
we prove that their performance in terms of energy resolution, background
rejection capability and intrinsic radio-purity complies with the requirements
of CUPID-0
CUPID-0: the first array of enriched scintillating bolometers for 0decay investigations
The CUPID-0 detector hosted at the Laboratori Nazionali del Gran Sasso, Italy, is the first large array of enriched scintillating cryogenic detectors for the investigation of82Se neutrinoless double-beta decay (0). CUPID-0 aims at measuring a background index in the region of interest (RoI) for 0at the level of 10- 3 counts/(keV kg years), the lowest value ever measured using cryogenic detectors. CUPID-0 operates an array of Zn82Se scintillating bolometers coupled with bolometric light detectors, with a state of the art technology for background suppression and thorough protocols and procedures for the detector preparation and construction. In this paper, the different phases of the detector design and construction will be presented, from the material selection (for the absorber production) to the new and innovative detector structure. The successful construction of the detector lead to promising preliminary detector performance which is discussed here
Search for 14.4 keV solar axions from M1 transition of Fe-57 with CUORE crystals
We report the results of a search for axions from the 14.4 keV M1 transition
from Fe-57 in the core of the sun using the axio-electric effect in TeO2
bolometers. The detectors are 5x5x5 cm3 crystals operated at about 10 mK in a
facility used to test bolometers for the CUORE experiment at the Laboratori
Nazionali del Gran Sasso in Italy. An analysis of 43.65 kg d of data was made
using a newly developed low energy trigger which was optimized to reduce the
detectors energy threshold. An upper limit of 0.63 c kg-1 d-1 was established
at 95% C.L.. From this value, a lower bound at 95% C.L. was placed on the
Peccei-Quinn energy scale of fa >= 0.76 10**6 GeV for a value of S=0.55 for the
flavor-singlet axial vector matrix element. Bounds are given for the interval
0.15 < S < 0.55.Comment: 14 pages, 6 figures, submitted to JCA
Transitioning to molecular diagnostics in pediatric high-grade glioma: Experiences with the 2016 WHO classification of CNS tumors
BACKGROUND:
Pediatric neuro-oncology was profoundly changed in the wake of the 2016 revision of the WHO Classification of Tumors of the Central Nervous System. Practitioners were challenged to quickly adapt to a system of tumor classification redefined by molecular diagnostics.
METHODS:
We designed a 22-question survey studying the impact of the revised WHO classification on pediatric high-grade glioma. The survey collected basic demographics, general attitudes, issues encountered, and opinions on pediatric subtypes. Participant answers were analyzed along socioeconomic lines utilizing the human development index (HDI) of the United Nations and membership in the group of seven (G7) world economic forum.
RESULTS:
Four hundred and sixty-five participants from 53 countries were included, 187 pediatric neurooncologists (40%), 160 neuropathologists (34%), and 118 other experts (26%). When asked about pediatric high-grade glioma entities, participants from very high development countries preferred treating a patient based on genetic findings. Participants from high and medium development countries indicated using traditional histology and tumor location as mainstays for therapeutic decisions. Non-G7 countries tended to regard the introduction of molecularly characterized tumor entities as a problem for daily routine due to lack of resources.
CONCLUSIONS:
Our findings demonstrate an overall greater reliance and favorability to molecular diagnostics among very high development countries. A disparity in resources and access to molecular diagnostics has left some centers unable to classify pediatric high-grade glioma per the WHO classification. The forthcoming edition should strain to abate disparities in molecular diagnostic availability and work toward universal adaptation
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