HERITABILITY AND PATH ANALYSIS OF SOME ECONOMICAL CHARACTERISTICS IN LENTIL

Twenty-nine lentil (Lens culinaris Medik) genotypes were grown from 1997/98 to 1998/2001 at Dicle University, Faculty of Agriculture in Diyarbakir The heritability for days to fl owering and maturity, plant height, height of lowest pod, number of pod per plant, 1000 seed weight and seed yield were estimated as 0.94, 0.78, 0.52, 0.72, 0.37, 0.87 and 0.53, respectively. The path analysis indicated that total biological yield and number of clusters and pods per plant had very high positive direct effect on seed yield

STABILITY PARAMETERS IN LENTIL

Fourteen lentil genotypes were tested for grain yield in Southeastern Anatolia ecological conditions, over our consecutive years to classify these cultivars for yield stability. Seed yield ranged from 1.903 t/ha to 1.367 t/ha. RM76, RM601 and RM152 showed regression coeffi cient above 1.00, but RM76 among these lines was consistently produced the highest yields. The unstable cultivars, RM601 and RM152 had the highest S2 values and high C.V. for grain yield

Study on Red Lentil Genotypes For Drought And Cold Tolerance And Yield Components

Abstract: This study was conducted at rainfall conditions in Southeastern Anatolia of Turkey, Diyarbakır, during 2011-2012 growing season. This work reviewed the three different lentil nurseries obtained from ICARDA; 1.Lentil International Elite Nursery-Drought Tolerance-2012, 2.Nursery-Early-2012 and 3.Nursery-Red-2012. The experiment was designed a simple lattice (7x7) and (6x6). Total one thousand twenty-two genotypes were evaluated for cold, drought tolerance and other agronomical and botanic traits. Wide variation observed for all traits among genotypes. Hopeful genotypes for earlier, more pods, average yield, drought and cold resistance were selected in first trial. The most genotypes affected by cold in all trials, also, some genotypes in plots killed by low temperature

Transpiration rate of chickpea wild accessions and cultivars in Turkey

Chickpea (Cicer arietinum L.), like most cultivated crops, has exceedingly narrow genetic and phenotypic diversity. Thus breeding with only cultivated germplasm will have steeply diminishing returns, raising an urgent need for new sources of diversity. The focus of the research was to assess a representative set of newly collected wild accessions of C. reticulatum and C. echinospermum, for drought adaptation traits, i.e. transpiration rate (TR) response to increasing VPD and to soil drying. These experiments were conducted during the spring season (18 March to 21 April 2016) at the Dicle University glasshouse. The experimental design was a complete randomised block design with six replications. Measurements were conducted in late April during vegetative growth and VPD changed from 2.13 to 4.35 kPa. To measure TR, potted plants were weighed at regular time intervals over the course of an entire day, and therefore, under increasing VPD. At the end of the experiment total leaf area was destructively measured, along with shoot, root and leaf dry weights. There was a 2.31-fold range of variation in the transpiration response among genotypes. The wild genotypes Sirnak and Deste had extreme TR values exceeding cultivated check cultivars, and several wild genotypes had only a moderate increase in TR under increasing VPD. These moderate TR responses provide germplasm sources with a potential to limit water losses under high evaporative demand, akin to a protection mechanism, especially under dry environments or in future climates. These screenings, therefore, open an exciting opportunity for breeding cultivars with enhanced performance under harsh climates

ChIP-Seq analysis identifies p27(Kip1)-target genes involved in cell adhesion and cell signalling in mouse embryonic fibroblasts.

The protein p27Kip1 (p27), a member of the Cip-Kip family of cyclin-dependent kinase inhibitors, is involved in tumorigenesis and a correlation between reduced levels of this protein in human tumours and a worse prognosis has been established. Recent reports revealed that p27 also behaves as a transcriptional regulator. Thus, it has been postulated that the development of tumours with low amounts of p27 could be propitiated by deregulation of transcriptional programs under the control of p27. However, these programs still remain mostly unknown. The aim of this study has been to define the transcriptional programs regulated by p27 by first identifying the p27-binding sites (p27-BSs) on the whole chromatin of quiescent mouse embryonic fibroblasts. The chromatin regions associated to p27 have been annotated to the most proximal genes and it has been considered that the expression of these genes could by regulated by p27. The identification of the chromatin p27-BSs has been performed by Chromatin Immunoprecipitation Sequencing (ChIP-seq). Results revealed that p27 associated with 1839 sites that were annotated to 1417 different genes being 852 of them protein coding genes. Interestingly, most of the p27-BSs were in distal intergenic regions and introns whereas, in contrast, its association with promoter regions was very low. Gene ontology analysis of the protein coding genes revealed a number of relevant transcriptional programs regulated by p27 as cell adhesion, intracellular signalling and neuron differentiation among others. We validated the interaction of p27 with different chromatin regions by ChIP followed by qPCR and demonstrated that the expressions of several genes belonging to these programs are actually regulated by p27. Finally, cell adhesion assays revealed that the adhesion of p27-/- cells to the plates was much higher that controls, revealing a role of p27 in the regulation of a transcriptional program involved in cell adhesion

Does primary brachial plexus surgery alter palliative tendon transfer surgery outcomes in children with obstetric paralysis?

<p>Abstract</p> <p>Background</p> <p>The surgical management of obstetrical brachial plexus palsy can generally be divided into two groups; early reconstructions in which the plexus or affected nerves are addressed and late or palliative reconstructions in which the residual deformities are addressed. Tendon transfers are the mainstay of palliative surgery. Occasionally, surgeons are required to utilise already denervated and subsequently reinnervated muscles as motors. This study aimed to compare the outcomes of tendon transfers for residual shoulder dysfunction in patients who had undergone early nerve surgery to the outcomes in patients who had not.</p> <p>Methods</p> <p>A total of 91 patients with obstetric paralysis-related shoulder abduction and external rotation deficits who underwent a modified Hoffer transfer of the latissimus dorsi/teres major to the greater tubercle of the humerus tendon between 2002 and 2009 were retrospectively analysed. The patients who had undergone neural surgery during infancy were compared to those who had not in terms of their preoperative and postoperative shoulder abduction and external rotation active ranges of motion.</p> <p>Results</p> <p>In the early surgery groups, only the postoperative external rotation angles showed statistically significant differences (25 degrees and 75 degrees for total and upper type palsies, respectively). Within the palliative surgery-only groups, there were no significant differences between the preoperative and postoperative abduction and external rotation angles. The significant differences between the early surgery groups and the palliative surgery groups with total palsy during the preoperative period diminished postoperatively (p < 0.05 and p > 0.05, respectively) for abduction but not for external rotation. Within the upper type palsy groups, there were no significant differences between the preoperative and postoperative abduction and external rotation angles.</p> <p>Conclusions</p> <p>In this study, it was found that in patients with total paralysis, satisfactory shoulder abduction values can be achieved with tendon transfers regardless of a previous history of neural surgery even if the preoperative values differ.</p

Age- and region-specific hepatitis B prevalence in Turkey estimated using generalized linear mixed models: a systematic review

Toy M, Önder FO, Wörmann T, et al. Age- and region-specific hepatitis B prevalence in Turkey estimated using generalized linear mixed models: a systematic review. BMC infectious diseases. 2011;11(1): 337.BACKGROUND: To provide a clear picture of the current hepatitis B situation, the authors performed a systematic review to estimate the age- and region-specific prevalence of chronic hepatitis B (CHB) in Turkey. METHODS: A total of 339 studies with original data on the prevalence of hepatitis B surface antigen (HBsAg) in Turkey and published between 1999 and 2009 were identified through a search of electronic databases, by reviewing citations, and by writing to authors. After a critical assessment, the authors included 129 studies, divided into categories: 'age-specific'; 'region-specific'; and 'specific population group'. To account for the differences among the studies, a generalized linear mixed model was used to estimate the overall prevalence across all age groups and regions. For specific population groups, the authors calculated the weighted mean prevalence. RESULTS: The estimated overall population prevalence was 4.57, 95% confidence interval (CI): 3.58, 5.76, and the estimated total number of CHB cases was about 3.3 million. The outcomes of the age-specific groups varied from 2.84, (95% CI: 2.60, 3.10) for the 0-14-year olds to 6.36 (95% CI: 5.83, 6.90) in the 25-34-year-old group. CONCLUSION: There are large age-group and regional differences in CHB prevalence in Turkey, where CHB remains a serious health problem

Erratum: Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

Interpretation: By quantifying levels and trends in exposures to risk factors and the resulting disease burden, this assessment offers insight into where past policy and programme efforts might have been successful and highlights current priorities for public health action. Decreases in behavioural, environmental, and occupational risks have largely offset the effects of population growth and ageing, in relation to trends in absolute burden. Conversely, the combination of increasing metabolic risks and population ageing will probably continue to drive the increasing trends in non-communicable diseases at the global level, which presents both a public health challenge and opportunity. We see considerable spatiotemporal heterogeneity in levels of risk exposure and risk-attributable burden. Although levels of development underlie some of this heterogeneity, O/E ratios show risks for which countries are overperforming or underperforming relative to their level of development. As such, these ratios provide a benchmarking tool to help to focus local decision making. Our findings reinforce the importance of both risk exposure monitoring and epidemiological research to assess causal connections between risks and health outcomes, and they highlight the usefulness of the GBD study in synthesising data to draw comprehensive and robust conclusions that help to inform good policy and strategic health planning