Turning conflicts into cooperation? The role of adaptive learning and deliberation in managing natural resources conflicts in Nepal

Conflicts over natural resources are likely to escalate under changing socio-economic contexts and climate change. This paper tests the effectiveness of what we term Adaptive Learning and Deliberation (ALD) in understanding and addressing conflicts over the local management of forests and water, drawing on the experimental works in Nepal. Based on a three-year action research, the paper offers policy and practical insights on how complex and protracted conflicts can be addressed through researcher-facilitated inquiry and deliberative process which forms the core of ALD approach. The conflicts included in the study are not solely triggered by climate change but are a result of diverse environmental changes, diverse policy responses to local issues of resource governance, and wider political and economic factors. We analyze experimental practices of ALD implemented in two sites, where our research team facilitated the ALD process, gathering evidence in relation to conflicting institutional issues, all of which was then fed into researcher-mediated and evidence informed deliberations on conflict management. The analysis shows that the ALD process was helpful in rearranging local institutions to accommodate the interests of the conflicting groups and, to some extent, challenge some of the underlying exclusionary provisions of forest and water institutions which have deep social roots in the Nepalese society. We also identify three key limitations of this approach – transaction costs, the need for strong research and facilitative capacity within the research team, and the acceptance of researchers' involvement among the conflicting stakeholders. Finally, we discuss some policy implications of the findings, including potential implications for building climate resilience

Let us conserve and exchange seeds: celebrating traditional crop diversity of the Nepali lowlands

A seed fair is an activity to create awareness about and appreciate local crop diversity, exchange seed and related knowledge, and celebrate farmers’ efforts to conserve agrobiodiversity. It takes considerable time and effort to organize a seed fair. This brief describes the seed fair organized at the Agyauli Community Seedbank, Nawalparasi in the southern region of Nepal. About 30 members of 10 community seedbanks from the terai (the southern lowland) region of Nepal came together for this. Apart from exchanging seeds of traditional crop varieties, they also shared stories about the socio-cultural, religious, spiritual, nutritional and medicinal values of their varieties. The recent formal registration of the Community Seed Banks Association of Nepal (CSBAN) was also celebrated

Herbage Mass and Chemical Composition of the Heterogeneous Grasslands Affected by Harvesting TIME in Subtropical Terrain Nepal

A study was carried out to evaluate the productivity and chemical composition of heterogeneous grasslands at Agriculture and Forestry University (AFU) livestock farm. The four grassland ecotypes were chosen as upland north, upland south, lowland south and lowland north. The dominating herbage species and cover abundance by the botanical groups were studied on day before the harvesting. Later, the herbage dry matter productivity was estimated by quadrat cutting during May and June, 2017. Chemical analysis was done by using the proximate method for dry matter (DM), crude protein (CP), crude fiber (CF) and ether extract (EE) content. Research results showed that the AFU grassland dominated by perennial grasses and sedges followed by the forbs. The mean coverage of grasses and sedges was about 55%, whilst that of forbs was about 29% and the least was for legumes (about 4%). The cumulative herbage mass was about 1.53 t/ ha on the DM basis, whilst the highest DM was found in the upland-south (1.74 t/ha) and the least was in the upland-north (1.334 t/ha). The proximate analysis further revealed that the site had no effect on CF content, whilst the CP was significant only at the second harvest for the lowland north (8.34%).  Data revealed that the herbage composition might depend upon the soil moisture availability and geographical aspect. The dominance of perennial grasses at AFU grasslands revealed the yield stability, but needs the improvement through inoculation with leguminous forages for improved feed quality

The Possible Application of Ketamine in the Treatment of Depression in Alzheimer\u27s Disease

Depression is a leading cause of disability globally, with a prevalence of 3.8% among the whole population, 5% of the adult population, and 5.7% of the elderly population over 60 years of age. There is evidence that depression is linked to certain neurodegenerative diseases, one being Alzheimer\u27s disease (AD). The efficacy of conventional antidepressants to treat depression in AD is conflicting, especially regarding selective serotonin reuptake inhibitors (SSRIs). A recent systemic review and meta-analysis of 25 randomized controlled trials including fourteen antidepressant medications showed no high efficacy in treating AD patients\u27 symptoms. However, ketamine, a nonselective N-methyl-D-aspartate (NMDA) receptor antagonist, can mediate a wide range of pharmacological effects, including neuroprotection, anti-inflammatory and anticancer properties, multimodal analgesia, and treatment of depression, suicidal attempts, and status epilepticus. Esketamine, which is ketamine formulated as a nasal spray, was approved by the Federal Drug Administration (FDA) in March 2019 as an adjuvant drug to treat treatment-resistant depression. NMDA receptor antagonists treat AD through offsetting AD-related pathological stimulation of subtypes of glutamate receptors in the central nervous system. Recent clinical findings suggest that ketamine may provide neuroprotection and reduce neuropsychiatric symptoms associated with AD. In the present investigation, we evaluate the potential role of ketamine and its postulated mechanism in AD management

SOCIO-PSYCHOLOGICAL STUDY AMONG INJECTABLE DRUG USERS IN KATHMANDU VALLEY

On the background of ever increasing HIV transmission in our community through various routes, the psychosocial factors related with intravenous drug abuse has become necessary to be studied. Aim of the study was to assess the Socio-psychological factors that influence people to use drugs, especially to use Injectable drugs. We enrolled a sample of 393 Intravenous drug users, all male, in the Kathmandu Valley. Participants were administered a semi structured proforma to assess the psychosocial issues related with the drug intravenous drug abuse. Mean age of the sample was 27.76+ 4.86 years. Majority were single, unemployed, Hindu and by caste Newars, with education more than high school (SLC or more). The first psychoactive substance use by most of them was cannabis. The most frequently used psychoactive substance was injection Buprenorphine (Tidigesic), which was followed by mixture of various substances (opiates, benzodiazepines, antihistamines) and Diacetyl morphine (Brown sugar). Factors associated with the start of the drugs were for enjoyment, friend’s pressure and to alleviate mental tension. Many accepted Injectable drug use contributing to problems in mental, marital, social, economic and legal aspects of their life. Despite knowing the harms caused by the drugs majority persist on its use. A needle exchange programme has been viewed positively by many. Key words: buprenorphin, needle sharing, needle replacement, HIV transmission

Trends in the availability of the vulture-toxic drug, diclofenac, and other NSAIDs in South Asia, as revealed by covert pharmacy surveys

SummaryThe catastrophic declines of three species of ‘Critically Endangered’ Gyps vultures in South Asia were caused by unintentional poisoning by the non-steroidal anti-inflammatory drug (NSAID) diclofenac. Despite a ban on its veterinary use in 2006 (India, Nepal, Pakistan) and 2010 (Bangladesh), residues of diclofenac have continued to be found in cattle carcasses and in dead wild vultures. Another NSAID, meloxicam, has been shown to be safe to vultures. From 2012 to 2018, we undertook covert surveys of pharmacies in India, Nepal and Bangladesh to investigate the availability and prevalence of NSAIDs for the treatment of livestock. The purpose of the study was to establish whether diclofenac continued to be sold for veterinary use, whether the availability of meloxicam had increased and to determine which other veterinary NSAIDs were available. The availability of diclofenac declined in all three countries, virtually disappearing from pharmacies in Nepal and Bangladesh, highlighting the advances made in these two countries to reduce this threat to vultures. In India, diclofenac still accounted for 10–46% of all NSAIDs offered for sale for livestock treatment in 2017, suggesting weak enforcement of existing regulations and a continued high risk to vultures. Availability of meloxicam increased in all countries and was the most common veterinary NSAID in Nepal (89.9% in 2017). Although the most widely available NSAID in India in 2017, meloxicam accounted for only 32% of products offered for sale. In Bangladesh, meloxicam was less commonly available than the vulture-toxic NSAID ketoprofen (28% and 66%, respectively, in 2018), despite the partial government ban on ketoprofen in 2016. Eleven different NSAIDs were recorded, several of which are known or suspected to be toxic to vultures. Conservation priorities should include awareness raising, stricter implementation of current bans, bans on other vulture-toxic veterinary NSAIDs, especially aceclofenac and nimesulide, and safety-testing of other NSAIDs on Gyps vultures to identify safe and toxic drugs.</jats:p

Genetics of grain yield and its components in wheat under heat stress

Heat stress is a matter of a great concern for the wheat crop. Heat stress usually either hastens crop development or shortens the grain filling duration, which severely reduces grain yield. Being a complex trait, understanding the genetics and gene interactions of stress tolerance are the two primary requirements for improving yield levels. Genetic analysis through generation mean analysis helps to find out the nature of gene actions involved in a concerned trait by providing an estimate of main gene effects (additive and dominance) along with their digenic interactions (additive × additive, additive × dominance, and dominance × dominance). In the present investigation, we elucidated the inheritance pattern of different yield contributing traits under heat stress using different cross combinations which could be helpful for selecting a suitable breeding strategy. Thus six generations of five crosses were sown normal (non-stress, TS) and late (heat stress, LS) in a randomized block design with three replications during two crop seasons. The model was not adequate for late sown conditions indicating the expression of epistatic genes under stress conditions. The traits i.e. Days to heading (DH), Days to anthesis (DA), Days to maturity (DM), Grain filling duration (GFD), Grain yield (GY), Thousand grain weight (TGW), Grain weight per spike (GWS) and Heat susceptibility index (HSI) under heat stress conditions were found under the control of additive gene action with dominance × dominance interaction, additive gene action with additive × dominance epistatic effect, dominance gene action with additive × additive interaction effect, additive and dominance gene action with dominance × dominance interaction effect, additive gene action with additive × dominance epistatic effect, additive gene action with additive × additive interaction effect and dominance gene action with additive × additive interaction effect, respectively

Dataset of phenotyping recombinant inbred lines population of wheat under heat stress conditions

The presented data included the phenotyping of parents and 249 RIL population of F8 and F9 generations derived from the cross between HUW510 and HD2808 wheat genotypes under timely and late sown conditions during the 2013-14 and 2014-15 crop seasons, respectively. A total of eight agronomic traits were subjected to phenotype and the heat susceptibility index (HSI) of these traits was estimated to identify the effect of heat stress on the parents and RIL population. The presented dataset could be utilized to understand the genetic basis for heat stress tolerance in wheatTHIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE. TO VIEW A LIST OF FILES AND ACCESS THE FILES IN THIS DATASET CLICK ON THE DOI-LINK ABOV