A REPORT ON FORMULATION AND DEVELOPMENT OF DIFFERENT DOSAGE FORMS

The new developed pharmaceutical formulation is related to the fact that it is able to deliver the active substance to the target organ at therapeutically relevant levels, with negligible discomfort and side effects, increasing the patient compliance to the therapeutics. Regarding this respect, the route of administration is of major relevance. Various methods of Novel Drug Delivery systems are used for the better patient compliance. During the recent decades several studies have suggested that novel drug delivery systems based on lipid nanoparticles have the potential of increasing cutaneous drug delivery of both hydrophilic and lipophilic drugs. Despite the substantial potential of transdermal and dermal drug delivery, only relatively few drugs are yet commercially available as topical formulations. The limitation lies in the barrier function of the skin function, which is considered one of the most impermeable epithelia of the human body to exogenous substances. The current review gathered information on the, formulation, advantages, and disadvantages of Tablet in Tablet or compression coating. The report also elaborates on the importance of Tablets in Tablet techniques in the development of a modified release system. And information on capsule types, formulation, advantages and disadvantages. And various instruments required in the laboratory practices

<span style="font-size:12.0pt;line-height: 115%;font-family:"Times New Roman";mso-fareast-font-family:"Times New Roman"; mso-ansi-language:EN-IN;mso-fareast-language:EN-IN;mso-bidi-language:HI" lang="EN-IN">Influence of antiangiogenic fraction from <i>Diogenes</i> <i>avarus</i> (Heller) on fertility and implantation in mice</span>

581-588<span style="font-size:12.0pt;line-height: 115%;font-family:" times="" new="" roman";mso-fareast-font-family:"times="" roman";="" mso-ansi-language:en-in;mso-fareast-language:en-in;mso-bidi-language:hi"="" lang="EN-IN">The methanol extract isolated from hermit crab, D. avarus degenerated ovarion and uterine ti ssues in cyclic and pregnant mice, treated before and after the implantation. Immunohi stochemical staining using CD31 and Factor VIII specific to endothelial cells showed reduction in microvessel density. The hormonal assay showed decrease in the progesterone secretion in all experimental mice. </span

Hereditary angioedema: Not an allergy

Hereditary angioedema is a genetic disorder due to a deficiency or malfunction of C1 esterase inhibitor. We herein describe a case of 25-year-old male who presented with swelling over face since one day. There was history of similar episodes since two years with gradual subsidence of swelling without any treatment. Investigations revealed grossly reduced complement C4 and C1 esterase inhibitor level. Patient was diagnosed to have hereditary angioedema type 1 and started on stanozolol 2 mg three times a day with no recurrence in one year of follow-up. Hereditary angioedema resembles angioedema of an allergic reaction. However, the cause is different

Passphrase and Keystroke Dynamics Authentication: Usable Security

It was found that employees spend a total of 2.25 days within 60 days on password-related activities. The time consumed by this is unproductive and has a negative impact on usability. The problem is caused by current text-based user authentication policies in use. This study aims to address this research problem by assessing the effectiveness of a proposed two-tier user authentication solution involving passphrases and keystroke dynamics