<span style="font-size:12.0pt;line-height: 115%;font-family:"Times New Roman";mso-fareast-font-family:"Times New Roman"; mso-ansi-language:EN-IN;mso-fareast-language:EN-IN;mso-bidi-language:HI" lang="EN-IN">Influence of antiangiogenic fraction from <i>Diogenes</i> <i>avarus</i> (Heller) on fertility and implantation in mice</span>

Abstract

581-588<span style="font-size:12.0pt;line-height: 115%;font-family:" times="" new="" roman";mso-fareast-font-family:"times="" roman";="" mso-ansi-language:en-in;mso-fareast-language:en-in;mso-bidi-language:hi"="" lang="EN-IN">The methanol extract isolated from hermit crab, D. avarus degenerated ovarion and uterine ti ssues in cyclic and pregnant mice, treated before and after the implantation. Immunohi stochemical staining using CD31 and Factor VIII specific to endothelial cells showed reduction in microvessel density. The hormonal assay showed decrease in the progesterone secretion in all experimental mice. </span