42 research outputs found
Flutter analysis of rotary laminated composite structures using higher-order kinematics
Abstract The flutter analysis of rotary laminated structures has been performed using Carrera Unified Formulation (CUF). CUF is a one-dimensional higher-order structural model, in which the displacement at the cross-section is the only unknown parameter. The cross-sectional displacement fields of the model are defined using the Lagrange- and Taylor expansion. The quasi-steady and unsteady theories (Theodorsen and Loewy) have been used to apply the aerodynamic force. Subsequently, the equation of motion is defined in 'fundamental nucleus' form using Hamilton's principle. The engineering solution of the flutter condition has been obtained by using p-k method. The computational studies of flutter analysis have been done for various rotor hub, lamination sequence, and structural models. The regular, irregular plies and arbitrary fiber orientation of the orthotropic structures have also been considered. The present study suggests that the proposed CUF model can obtain an aeroelastic solution of rotary structure in a computationally and economically efficient manner
Frustrated and Confused: Mapping the Socio-political Struggles of Female Ex-combatants in Nepal
The Communist Party of Nepal (Maoist) declared an armed insurrection against the State in February 1996; they began to attack police posts and gradually the insurrection was sparked all over the country, lasting for ten years. Consequently, it caused 17,886 deaths, 79,571 displacements, 1,530 disappearances, 3,142 abductions, 8,935 disabilities, and left 620 children orphaned (MoPR 2016). In the armed conflict 20 percent of Maoist combatants were women. After several rounds of negotiations, the armed conflict ended in November 2006, with the signing of the Comprehensive Peace Agreement (CPA) between the Government of Nepal and the then Communist Party of Nepal (Maoist) that demanded disarmament, demobilization and reintegration (DDR) of the Maoist ex-combatants. Among the ex-combatants the DDR process for reintegrating female ex-combatants was more complicated. This paper examines the DDR process with a specific focus on ex-combatants. Focus group interviews, key informant interviews, roundtable discussions, and direct interviews with the female- ex-combatants were the methods used in collecting data, in addition to secondary sources. This paper argues that the DDR was not only contested, but also procedurally flawed, and therefore not able to produce the desired result. Because the DDR was a complex, socio-psychological and politico-economic process and required sensitive handling, key Nepali actors and international supporters failed to properly deal with the DDR. The DDR process was largely gender-blind and therefore, the female ex-combatants suffered more in terms of their social relations, specific needs and achieving livelihood security. The approach of United Mission to Nepal (UNMIN) was one of the reasons; consequently, its engagement was terminated without completing the DDR process mainly because it failed to internalize gender sensitivity and local complexity
Temporal expression of thyroid hormone regulating genes (tsh-b, tsh-r, dio2 and dio3) and their correlation with annual reproductive cycle of the Indian freshwater catfish, Heteropneustes fossilis (Bloch).
Photoperiod and temperature are well-established environmental cues for gonadal growth in seasonally reproducing organisms. The photoperiod is known to regulate seasonal reproduction via induction of thyroid hormone regulating genes in the saccus vasculosus (SV) of fishes. However, SV is absent in many seasonally breeding fishes, including Heteropneustes fossilis. H. fossilis is a long-day breeding catfish in which gonadal recrudescence begins six months earlier than spawning. The present study attempted to analyse the expression of thyroid hormone-regulating genes (tsh-b, tsh-r, dio2 and dio3) in the brain, liver and ovary. In the brain, upregulated expression of thyrotropin-beta subunit (tsh-b), deiodinase2 (dio2) and deiodinase3 (dio3) genes is concomitant with the increasing photoperiod and temperature in nature, which may appear to regulate seasonal reproduction. Both deiodinases, dio2 and dio3, were also upregulated in the liver and ovarian tissue during the gonadal growth phase. The upregulation of deiodinases may enhance the metabolism and activity of tissues, thereby facilitating their respective roles. The expression of these genes was also assessed in the brain, liver, ovary, kidney, skin, spleen and gill tissues during the spawning period. The ubiquitous expression of deiodinases may point to enhanced activity in their organ-specific role. The present study speculates that expression of tsh-b, tsh-r, dio2 and dio3 genes during the reproductive phase of H. fossilis might be involved in the regulation of seasonal reproduction
Effects of planting configuration and row spacing on growth and production of potato under mulched condition in Dadeldhura, Nepal
An experiment was conducted at the research site of Dadeldhura, Nepal in 2019 to identify optimum plant spacing for potato under mulched condition. Three levels of inter row spacing; 60 cm with single row per bed (1RB), 45 cm with double row per bed (2RB) and 30 cm with triple row per bed (3RB) and intra row spacing (20, 30 and 40 cm) were laid out in factorial randomized complete block design with three replications. Results showed that there was significant difference (p<0.05) for all parameters except on days to 50% germination, 90% flowering, 50% maturity and on main stem number and graded large sized tuber number and it's weight. Growth parameters namely canopy, leaf number and leaf area were significantly higher (p<0.05) in 60 cm (1RB) Ă30 cm spacing. Plant height and leaf area index was significantly higher (p<0.05) in 60 cm (1RB) Ă 20 cm and 30(3RB) Ă20 cm spacing respectively. Total number of tubers m-2 , weight of tubers m-2, weight of marketable tubers m-2, harvest index, number of small sized tuber m-2 ,weight of small sized tubers m-2 and weight of medium sized tubers m-2 were found to be 56.24%,39.79%, 47.98%,4.41%,90.56%, 113.23% and 70.15% significantly higher (p<0.05) in 30 cm (3RB) compared to 60 cm on (1RB) inter row spacing respectively and 59.72%, 61.15%, 58.30%, 4.41%, 114.90%, 137.31%, 55.39% higher in 20cm compared to 40 cm intra row spacing. Interaction effect was significant (p<0.05) in marketable tuber number and medium sized tuber number in which the average highest number of marketable tubers (134.44) and medium sized tubers (121.08) was found in 30(3RB) Ă20 cm spacing which was 165.95% and 235.03% significantly higher compared to 60Ă40 cm spacing respectively. So, this study showed that 30(3RB) Ă20 cm spacing would be best spacing combination under mulched condition
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The COVIDâ19 Pandemic Not Only Poses Challenges, but Also Opens Opportunities for Sustainable Transformation
The COVID-19 pandemic has impacted social, economic, and environmental systems worldwide, slowing down and reversing the progress made in achieving the Sustainable Development Goals (SDGs). SDGs belong to the 2030 Agenda to transform our world by tackling humankind's challenges to ensure well-being, economic prosperity, and environmental protection. We explore the potential impacts of the pandemic on SDGs for Nepal. We followed a knowledge co-creation process with experts from various professional backgrounds, involving five steps: online survey, online workshop, assessment of expert's opinions, review and validation, and revision and synthesis. The pandemic has negatively impacted most SDGs in the short term. Particularly, the targets of SDG 1, 4, 5, 8, 9, 10, 11, and 13 have and will continue to have weakly to moderately restricting impacts. However, a few targets of SDG 2, 3, 6, and 11 could also have weakly promoting impacts. The negative impacts have resulted from impeding factors linked to the pandemic. Many of the negative impacts may subside in the medium and long terms. The key five impeding factors are lockdowns, underemployment and unemployment, closure of institutions and facilities, diluted focus and funds for non-COVID-19-related issues, and anticipated reduction in support from development partners. The pandemic has also opened a window of opportunity for sustainable transformation, which is short-lived and narrow. These opportunities are lessons learned for planning and action, socio-economic recovery plan, use of information and communication technologies and the digital economy, reverse migration and âbrain gain,â and local governments' exercising authorities
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Burden and predictors of hypertension in India: results of SEEK (Screening and Early Evaluation of Kidney Disease) study
Background: Hypertension (HTN) is one of the major causes of cardiovascular morbidity and mortality. The objective of the study was to investigate the burden and predictors of HTN in India. Methods: 6120 subjects participated in the Screening and Early Evaluation of Kidney disease (SEEK), a community-based screening program in 53 camps in 13 representative geographic locations in India. Of these, 5929 had recorded blood pressure (BP) measurements. Potential predictors of HTN were collected using a structured questionnaire for SEEK study. Results: HTN was observed in 43.5% of our cohort. After adjusting for center variation (p < 0.0001), predictors of a higher prevalence of HTN were older age â„40 years (p < 0.0001), BMI of â„ 23 Kg/M2 (p < 0.0004), larger waist circumference (p < 0.0001), working in sedentary occupation (p < 0.0001), having diabetes mellitus (p < 0.0001), having proteinuria (p < 0.0016), and increased serum creatinine (p < 0.0001). High school/some college education (p = 0.0016), versus less than 9th grade education, was related with lower prevalence of HTN. Of note, proteinuria and CKD were observed in 19% and 23.5% of HTN subjects. About half (54%) of the hypertensive subjects were aware of their hypertension status. Conclusions: HTN was common in this cohort from India. Older age, BMI â„ 23 Kg/M2, waist circumference, sedentary occupation, education less, diabetes mellitus, presence of proteinuria, and raised serum creatinine were significant predictors of hypertension. Our data suggest that HTN is a major public health problem in India with low awareness, and requires aggressive community-based screening and education to improve health
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Epidemiology and risk factors of chronic kidney disease in India â results from the SEEK (Screening and Early Evaluation of Kidney Disease) study
Background: There is a rising incidence of chronic kidney disease that is likely to pose major problems for both healthcare and the economy in future years. In India, it has been recently estimated that the age-adjusted incidence rate of ESRD to be 229 per million population (pmp), and >100,000 new patients enter renal replacement programs annually. Methods: We cross-sectionally screened 6120 Indian subjects from 13 academic and private medical centers all over India. We obtained personal and medical history data through a specifically designed questionnaire. Blood and urine samples were collected. Results: The total cohort included in this analysis is 5588 subjects. The mean ± SD age of all participants was 45.22 ± 15.2 years (range 18â98 years) and 55.1% of them were males and 44.9% were females. The overall prevalence of CKD in the SEEK-India cohort was 17.2% with a mean eGFR of 84.27 ± 76.46 versus 116.94 ± 44.65 mL/min/1.73 m2 in non-CKD group while 79.5% in the CKD group had proteinuria. Prevalence of CKD stages 1, 2, 3, 4 and 5 was 7%, 4.3%, 4.3%, 0.8% and 0.8%, respectively. Conclusion: The prevalence of CKD was observed to be 17.2% with ~6% have CKD stage 3 or worse. CKD risk factors were similar to those reported in earlier studies. It should be stressed to all primary care physicians taking care of hypertensive and diabetic patients to screen for early kidney damage. Early intervention may retard the progression of kidney disease. Planning for the preventive health policies and allocation of more resources for the treatment of CKD/ESRD patients are imperative in India
Climate change and water availability in western Nepal
The response of any hydrological system to climate change may differ depending on characteristics of the system. Such studies are lacking for basins in Western Nepal. This paper, therefore, argues for a need to re-phrase the context of Western Nepal in more positive light and then analyses how a projected change in climate may impact on water availability of the region with a case of Chamelia watershed. A hydrological model in SWAT (Soil and Water Assessment Tool) environment is developed for the purpose. Future climate is projected using a set of fi ve Regional Circulation Models (RCMs). Then response of streamfl ow with projected change in climate is assessed. Results show the developed model performance is adequate to represent hydrological characteristics of the watershed. Future is projected to be warmer (high model consensus) and slightly wetter (more uncertainty), with winter and premonsoon season receiving more rainfall. Under the projected future changes, simulated stream fl ow is projected to change across future periods and seasons. The results are expected to be useful for future water resource and water infrastructure planning in the area