91 research outputs found
Nuclear Photoabsorption at Photon Energies between 300 and 850 Mev
We construct the formula for the photonuclear total absorption cross section
using the projection method and the unitarity relation. Our treatment is very
effective when interference effects in the absorption processes on a nucleon
are strong. The disappearance of the peak around the position of the
resonance in the nuclear photoabsorption can be explained with the cooperative
effect of the interference in two-pion production processes,the Fermi motion,
the collision broadenings of and , and the pion distortion in the
nuclear medium. The change of the interference effect by the medium plays an
important role.Comment: 22pages,7figures,revtex
Genetics and other factors in the aetiology of female pattern hair loss.
Pattern hair loss is the most common form of hair loss in both women and men. Male pattern hair loss, also termed male androgenetic alopecia (M-AGA), is an androgen-dependent trait that is predominantly genetically determined. Androgen-mediated mechanisms are probably involved in FPHL in some women but the evidence is less strong than in M-AGA; and other non-androgenic pathways, including environmental influences, may contribute to the aetiology. Genome-wide association studies (GWASs) have identified several genetic loci for M-AGA and have provided better insight into the underlying biology. However, the role of heritable factors in female pattern hair loss (FPHL) is largely unknown. Recently published studies have been restricted to candidate gene approaches and could not clearly identify any susceptibility locus/gene for FPHL but suggest the aetiology differs substantially from that of M-AGA. Hypotheses about possible pathomechanisms of FPHL as well as the results of the genetic studies performed to date are summarized. This article is protected by copyright. All rights reserved
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Statement from the frontal fibrosing alopecia international expert alliance: SOFFIA 2024
Background
As the incidence of frontal fibrosing alopecia (FFA) continues to rise, there is a need for an optimal treatment algorithm for FFA.
Objective
To produce an international consensus statement on the treatment modalities and prognostic indicators of FFA.
Methods
Sixty-nine hair experts from six continents were invited to participate in a three-round Delphi process. The final stage was held as a virtual meeting facilitated via Zoom. The consensus threshold was set at ≥66%.
Results
Of 365 questions, expert consensus was achieved in 204 (56%) questions following completion of the three rounds. Three additional questions were included at the final meeting. The category with the strongest consensus agreement was disease monitoring (9; 100%). Questions pertaining to physical therapies achieved the least category consensus (15; 40%), followed by systemic therapy (45; 43%).
Limitations
The study lacked sufficient representation from Africa and South America.
Conclusion
SOFFIA highlights areas of agreement and disagreement among experts. Robust research is warranted to provide evidence-based treatment recommendations
Point View in Bird and Flower Painting
在中国传统绘画中,点景是极其重要的一种表达方式。石涛所研究的绘画问题中,情感、理性、力量都是不可缺少的,如何恰当地运用这三者,却有可能导致完全不同的创作结果。而点景正是这三者的集合点,不仅要用心灵去感受自然对象的内在精神,不能因为对象的限制而使感受层次也受到限制,把眼睛之受升华为心理之受。在绘画作品中合理地运用点景能使画家的情感与物象更加融合,画家自身的主观感受在画面上得到充分的体现,以一种小的特殊表现符号流露出画家作品里表达的象征倾向和审美概念,对画面的构图及意境有着画龙点睛的作用。本文以花鸟画点景为研究对象,重点介绍了点景的表现与意义;进一步阐述了点景在传统花鸟画构成中的作用,着重论述其在...The “point view” is extremely important as a means of expression in the traditional Chinese painting. Emotion, rationality and power are essential in the Shi Tao studied painting, and how to properly use them may lead to the creation of a completely different result. For the reason that “point view” is a collection of these three points, shouldn’t we only use the soul to feel the inner spirit of n...学位:文学硕士院系专业:艺术教育学院美术系_美术学学号:1862007115166
Genetik der monogenen isolierten Alopezien
Zusammenfassung
Die monogen vererbten isolierten Alopezien umfassen eine Gruppe klinisch und genetisch heterogener Formen von Haarlosigkeit/-verlust. Die klinische Unterteilung der isolierten Alopezien erfolgt nach Erkrankungsbeginn, betroffenen Regionen und Struktur des Haarschafts. Frauen und Männer sind gleichermaßen betroffen, die Vererbung ist autosomal-dominant oder autosomal-rezessiv. Seit der Identifizierung des Keratingens KRT86 als Ursache für die so genannte Monilethrix im Jahr 1997 konnten in der letzten Dekade Mutationen in 9 weiteren Genen für verschiedene Formen isolierter Alopezien identifiziert werden, darunter weitere Keratingene (KRT81 und KRT83) für die Monilethrix, das Hairless-Gen für die Atrichia congenita/papuläre Atrichie, das Corneodesmosingen für die autosomal-dominante Form der Hypotrichosis simplex sowie die Gene Desmoglein 4, Lipase H und der G-Protein gekoppelte Rezeptor P2RY5 (LPAR6) für autosomal-rezessive Formen der Hypotrichose. Molekulargenetische und pathophysiologische Untersuchungen dieser seltenen Haarentwicklungsstörungen trugen entscheidend dazu bei, grundlegende Mechanismen des Haarausfalls und somit auch physiologische Mechanismen des Haarwachstums besser zu verstehen.</jats:p
Novel mutation for disseminated superficial actinic porokeratosis and its functional impact at the protein level
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