Steps to Follow at a Dance

Fine manners are like personal beauty-a letter of credit everywhere. - C. A. Bartol. The formal season is a good time to inspect your manners and see just how they stand. Formal dances are not much different from other dances except in the matter of dress. Of course, everyone is more dignified when dressed in formal attire-at least, he should be

Turn Your Spare Time into Gifts

Christmas reminds me of Santa Claus and Santa Claus reminds me that I have ten million gifts to get for that many people. Now that I\u27m in school my allowance won\u27t allow me to spend very much for gifts. The best thing for me to do is to make what I give this year. I must get started right away using all my spare moments

Should Women Have Careers? College Men Say -- No!

Women should not have careers! If you don\u27t believe it, ask the opinion of some college men. Though they may make a few exceptions after awhile, they are generally agreed that woman\u27s place is in the home and that she should stay there

Improving Learning in Rural Lower Primary School through Provision of Informal ECD: Lessons from an NGO Model in Uganda

Despite the importance of early childhood education in improving academic achievements in subsequent years and also in social development, it remains out of reach for majority of children in developing countries. This leaves informal education as the main preparation children in rural areas receive before entry into primary schools. This paper focuses on contributions of informal early childhood education to pupils learning in lower primary schools. Data was drawn from a three-year longitudinal study of children who had benefitted from the informal early childhood education provided by a nongovernmental organization (LABE), in Uganda. Findings show that attendance of informal home based learning improves pupils’ performance in literacy and numeracy by primary three. Children who attend the informal early childhood education performed better than those who start school direct from home. Informal early childhood education also increases children readiness for schools and helps them cope better with school. The paper recommends adaptation of the LABE model in rural areas with inadequate formal ECCE provisions. In addition, for improved supervision, linking HLC and primary schools is critical

Teaching homophones in grades one, two and three

Thesis (Ed.M.)--Boston Universit

The Relationship Between Interaction Time and Reading and Math Achievement for Chapter I Students Using Computer-Assisted Instruction in Grades Three, Four and Five.

The role of computer technology, particularly computer-assisted instruction, in the educational delivery system has steadily increased over the last decade. Although the largest number of CAI programs can be categorized as drill and practice, an increasing number of high quality simulation and tutorial programs are becoming available. The interactive nature of CAI is supported by the learning theories of Piaget, Gagne, and other learning theorists. Research on the topic indicates that CAI has a generally positive effect on student achievement and fosters positive attitudes among students and instructors toward the learning environment. This research study had two goals. The first was to compare achievement as measured by a standardized achievement test for Chapter I students using CAI in reading and math and the achievement of Chapter I students not using CAI. The second goal of this project was to measure the relationship between computer interaction time and achievement. Findings indicated that reading achievement was higher for students who received CAI in reading and math. Achievement in reading and math was found to be higher for third grade students who received CAI in math compared to fourth and fifth grade students. Findings also indicated that computer interaction time in math was positively related to certain measures of math achievement for third grade students in the study

Potent modulation of the CepR quorum sensing receptor and virulence in a Burkholderia cepacia complex member using non-native lactone ligands

This work is licensed under a Creative Commons Attribution 4.0 International License.The Burkholderia cepacia complex (Bcc) is a family of closely related bacterial pathogens that are the causative agent of deadly human infections. Virulence in Bcc species has been shown to be controlled by the CepI/CepR quorum sensing (QS) system, which is mediated by an N-acyl L-homoserine lactone (AHL) signal (C8-AHL) and its cognate LuxR-type receptor (CepR). Chemical strategies to block QS in Bcc members would represent an approach to intercept this bacterial communication process and further delineate its role in infection. In the current study, we sought to identify non-native AHLs capable of agonizing or antagonizing CepR, and thereby QS, in a Bcc member. We screened a library of AHL analogs in cell-based reporters for CepR, and identified numerous highly potent CepR agonists and antagonists. These compounds remain active in a Bcc member, B. multivorans, with one agonist 250-fold more potent than the native ligand C8-AHL, and can affect QS-controlled motility. Further, the CepR antagonists prolong C. elegans survival in an infection model. These AHL analogs are the first reported non-native molecules that both directly modulate CepR and impact QS-controlled phenotypes in a Bcc member, and represent valuable chemical tools to assess the role of QS in Bcc infections

The Iowa Homemaker vol.16, no.7

Menus for the College Miss by Katherine Hoffman, page 2 Fun to Make Scrapbooks by Alvina Iverson, page 3 A Party to Remember by Beth Cummings, page 4 Dan Cupid Counts His Candles by Jean Reis, page 5 College Coed on Parade by Gaynold Carroll, page 6 Food – I Sing of Thee! By Marie Bernds, page 7 What’s New in Home Economics, page 8 Roomate or Ruffian by Peggy Schenk, page 10 Steps to Follow at a Dance by Josephine Betty, page 11 College and Business Get Together by Josephine Wylie Drips, page 11 Careers and Marriages Beckon Our Grads by Faithe Danielson, page 12 Are Hose and Holes Roommates? by Ruth Kunerth, page 13 Spray It! by Carol Brueck, page 13 Poor Eyesight Creates Modern Art by Bernadine Landsberg, page 14 Behind Bright Jackets, page 15 Don’t Scrub, Carve! by Peggy Schenk, page 16 Furniture of 1937 by Marjorie Pettinger, page 1

The Iowa Homemaker vol.16, no.6

Cooperation Transforms Work Into Play by Helen Clark and Charlotte Heffner, page 2 Modernize Your Walls by Virginia Berry, page 3 Take a Hint from Sally by Gaynold Carroll, page 4 Should Women Have Careers? by Josephine Betty, page 6 Many Foods Make Their Debut by Jean Reis and Clare Pell, page 7 What’s New in Home Economics, page 8 The Woman’s Place in Politics by Dorothy Fedderson, page 11 Mrs. Chang Serves a Chinese Dinner by Helen Peg Belken, page 12 Graduates in New Positions by Faithe Danielson, page 13 Extend the Holiday Hilarity by Marie Larson, page 14 Shopping for Hose by Rosalie Ralston, page 15 Hints for the Coed, page 1

De Novo ORFs in Drosophila Are Important to Organismal Fitness and Evolved Rapidly from Previously Non-coding Sequences

Funding for Open Access provided by the UMD Libraries Open Access Publishing Fund.How non-coding DNA gives rise to new protein-coding genes (de novo genes) is not well understood. Recent work has revealed the origins and functions of a few de novo genes, but common principles governing the evolution or biological roles of these genes are unknown. To better define these principles, we performed a parallel analysis of the evolution and function of six putatively protein-coding de novo genes described in Drosophila melanogaster. Reconstruction of the transcriptional history of de novo genes shows that two de novo genes emerged from novel long non-coding RNAs that arose at least 5 MY prior to evolution of an open reading frame. In contrast, four other de novo genes evolved a translated open reading frame and transcription within the same evolutionary interval suggesting that nascent open reading frames (proto-ORFs), while not required, can contribute to the emergence of a new de novo gene. However, none of the genes arose from proto-ORFs that existed long before expression evolved. Sequence and structural evolution of de novo genes was rapid compared to nearby genes and the structural complexity of de novo genes steadily increases over evolutionary time. Despite the fact that these genes are transcribed at a higher level in males than females, and are most strongly expressed in testes, RNAi experiments show that most of these genes are essential in both sexes during metamorphosis. This lethality suggests that protein coding de novo genes in Drosophila quickly become functionally important.This work was supported by NSF Grant #mcb0920196 and a Royster Society Fellowship from the University of North Carolina. Open Access publication fees were provided by the University of Maryland Libraries Open Access Publishing Fund. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript