1,825 research outputs found

    Brane World Cosmic String Interaction

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    It is shown that brane world gravity produces an attractive force between cosmic strings, in contrast to conventional Einstein gravity. This force is sufficient for stable bound states of Type II strings (which normally repel each other) to form. There is a small separation between the strings, giving them a rope-like structure. At astronomical scales these `cosmic ropes' resemble higher winding number strings, and so all brane world cosmic strings are effectively Type I.Comment: 5 page

    Desenvolvimento de interacções pessoais na construção de blogues no âmbito da disciplina de biologia/geologia : um estudo preliminar

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    Este documento apresenta resultados preliminares de um estudo de caso desenvolvido no âmbito do Doutoramento em Didáctica das Ciências, onde se utilizaram as tecnologias informáticas em contexto educativo, numa turma do Ensino Secundário. O projecto desenvolvido propôs-se analisar a utilização de blogues como complemento nas aprendizagens em Biologia/Geologia, com enfoque nas CTSA. Pretendeu ainda analisar como se construíram as relações interpessoais entre os membros do projecto, realizado com recurso a trabalho de grupo. Estratégias que envolvam as chamadas “novas tecnologias” são importantes na Educação dos jovens para a sociedade actual também conhecida por “sociedade do conhecimento”

    The education of children in care in North East England

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    This report presents findings from a multi-strategy study conducted by UCL Institute of Education, commissioned by and in collaboration with Virtual School Headteachers (VSH) from across the twelve local authorities (LA) in North East England and DAppEdPsy Educational Psychology students from Newcastle University. The overall aim of the project was to gain an insight into teaching and learning practice in schools in North East England at the pupil and whole school level to support the education of children in care. Previously reported research has often highlighted many of the shortcomings of provision in schools and how the education system collectively has not always met the education needs of children and young people in care. It was within this national and regional context that the North East England region of Virtual School Headteachers wanted to learn more about the effective teaching and learning of children and young people in care. Moreover, this study purposefully identified a group of children who had very positive experiences of education and were thriving in their settings, in order to learn more about what success looks like in schools to support the education of children and young people in care. Over the spring and summer terms of 2018, data were collected from an e-survey of over 400 designated teachers (DT) across North East England, focus group meetings with DTs, face-to-face interviews with children and lesson observations. The research is one of the first large scale studies in England to investigate, in depth, teaching and learning practices in schools, for a group of children and young people who experience significant disadvantage

    A probable early 16th century colonial shipwreck in the Portuguese coast

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    UIDB/04666/2020 UIDP/04666/2020The Ria de Aveiro F site was discovered during preventive archaeological works carried out in the scope of the 2002 expansion of Aveiro’s harbour into the Ria de Aveiro, a lagoon system located in northern Portugal which played a great role in the salt trade of the Early Modern period. Despite the global destruction of the context caused by the dredging works, several well preserved structural elements were recovered. They belonged to two ships, a carvel-built one and a clinker-built one. The former features several construction characteristics that are common in the Mediterranean. The latter possibly corresponds to a small support boat. Beside the structural findings, several rigging elements wooden and rope artifacts, some pottery shards, ballast stones and a limestone cannonball were also recovered. The global study of the findings allowed to assign these remains to a chronology around the first half of the 16th century. Wood identification analysis were recently carried out; the results indicate the use of tropical, South American species in the construction of the clinker-built vessel. This data allows us to suggest that this site may belong to an initial phase of the relationship between the Americas and the Iberian Peninsula.publishersversionpublishe

    Peripartum Cardiomyopathy. Post Partum Cardiorespiratory Arrest Complicated by Placental Accretism

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    Peripartum cardiomiopathy is a rare and life-threatening cardiac disease that affects young women previously healthy, during the peripartum period. It is a form of dilated cardiomyopathy with left-sided systolic dysfunction, which may lead to symptoms and signs of congestive heart failure. The exclusion diagnosis is based essentially on clinical presentation and initial symptoms may mimic physiologic alterations of pregnancy. The authors present a case of a 34 week multiple gestation with a growth restriction of one of the fetus and with a suspicion of a mild pre-eclampsia, motive by which we decided labour induction. During placental expulsion, in which we noticed difficulty in finding placental cleavage, the patient presented an assistoly, recovering after cardiorespiratory reanimation. However, the profuse bleeding after labour leaded to a life saving hysterectomy. Histological examination revealed placenta accreta. The echocardiography performed post-operatively diagnosed a dilated cardiomyopathy

    Promoting the achievement of looked after children and young people in South Tyneside

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    As of March 2016, there were 70,440 children and young people in care in England. The number of looked after children has continued to increase steadily over the last eight years. Sixty per cent of these children are in care because of abuse or neglect and three-quarters are placed in foster care arrangements. Children and young people who are in or have experienced care remain one of the lowest performing groups in terms of educational outcomes. Last year, 14% of looked after children achieved five or more A*–C GCSEs or equivalent, including English and mathematics. As a consequence, they also experience poorer employment and health outcomes after leaving school compared to their peers. They are over-represented amongst the offender population and those who experience homelessness. However, research is emerging to show that children and young people in care can have very positive experiences of school and are supported effectively to reach their full potential academically and socially. The purpose of this report is to share practice in selected South Tyneside schools that is contributing to improved outcomes and school experiences for children and young people in care. In July 2015, the South Tyneside Virtual School (VS) collaborated with UCL Institute of Education to run their Promoting the Achievement of Looked After Children (PALAC) programme with seven schools in the local authority (LA). This report presents an account of the programme, including the activities undertaken by the participants and the outcomes of the programme to date for students in care and staff in the participating school

    Parkinsonian phenotype in Machado-Joseph disease (MJD/SCA3): a two-case report

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    Background: Machado-Joseph disease (MJD), or spinocerebellar ataxia type 3 (SCA3), is an autosomal dominant neurodegenerative disorder of late onset, which is caused by a CAG repeat expansion in the coding region of the ATXN3 gene. This disease presents clinical heterogeneity, which cannot be completely explained by the size of the repeat tract. MJD presents extrapyramidal motor signs, namely Parkinsonism, more frequently than the other subtypes of autosomal dominant cerebellar ataxias. Although Parkinsonism seems to segregate within MJD families, only a few MJD patients develop parkinsonian features and, therefore, the clinical and genetic aspects of these rare presentations remain poorly investigated. The main goal of this work was to describe two MJD patients displaying the parkinsonian triad (tremor, bradykinesia and rigidity), namely on what concerns genetic variation in Parkinson's disease (PD) associated loci (PARK2, LRRK2, PINK1, DJ-1, SNCA, MAPT, APOE, and mtDNA tRNAGln T4336C). Case presentation: Patient 1 is a 40 year-old female (onset at 30 years of age), initially with a pure parkinsonian phenotype (similar to the phenotype previously reported for her mother). Patient 2 is a 38 year-old male (onset at 33 years of age), presenting an ataxic phenotype with parkinsonian features (not seen either in other affected siblings or in his father). Both patients presented an expanded ATXN3 allele with 72 CAG repeats. No PD mutations were found in the analyzed loci. However, allelic variants previously associated with PD were observed in DJ-1 and APOE genes, for both patients. Conclusions: The present report adds clinical and genetic information on this particular and rare MJD presentation, and raises the hypothesis that DJ-1 and APOE polymorphisms may confer susceptibility to the parkinsonian phenotype in MJD
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