35 research outputs found

    One Year After Enrollment in Literacy Programs: A Study of Changes in Learners\u27 Lives

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    The study examined changes in the lives of 450 Tennessee adults one year after they enrolled in literacy programs. Among the findings were: increase in rate of employment, in participants’ self-esteem, in their involvement in community organizations, and in some literacy practices

    You are activated, proud of it : A Study of Learner Identified Impacts of Participation in Adult Literacy Programs

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    This study is based on life history interviews with ten adult literacy students. It examines how adults describe the impacts of their participation in adult literacy classes on their lives, and how the impacts they define compare with performance measures in the new Workforce Investment Act

    Parasite Evolution and Life History Theory

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    Beth F. Kochin is with Emory University, James J. Bull is with UT Austin, Rustom Antia is with Emory University.As a group, parasites are extraordinarily diverse. Even closely related parasites may behave very differently, infecting different host species, causing different pathologies, or infecting different tissues. For example, Escherichia coli bacteria, a typically harmless inhabitant of the human gut, can, in different forms, cause diarrhea, intestinal bleeding, urinary tract infections, kidney bleeding, meningitis, and other diseases. Underlying this diversity is evolution.This work is supported by the National Institutes of Health and the Fannie and John Hertz Foundation. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Cellular and Molecular Biolog

    Intelligent Systems for Geosciences: An Essential Research Agenda

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    A research agenda for intelligent systems that will result in fundamental new capabilities for understanding the Earth system. Many aspects of geosciences pose novel problems for intelligent systems research. Geoscience data is challenging because it tends to be uncertain, intermittent, sparse, multiresolution, and multiscale. Geosciences processes and objects often have amorphous spatiotemporal boundaries. The lack of ground truth makes model evaluation, testing, and comparison difficult. Overcoming these challenges requires breakthroughs that would significantly transform intelligent systems, while greatly benefitting the geosciences in turn

    Radiation Induced Apoptosis of Murine Bone Marrow Cells is Independent of Early Growth Response 1 (EGR1)

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    An understanding of how each individual 5q chromosome critical deleted region (CDR) gene contributes to malignant transformation would foster the development of much needed targeted therapies for the treatment of therapy related myeloid neoplasms (t-MNs). Early Growth Response 1 (EGR1) is a key transcriptional regulator of myeloid differentiation located within the 5q chromosome CDR that has been shown to regulate HSC (hematopoietic stem cell) quiescence as well as the master regulator of apoptosis—p53. Since resistance to apoptosis is a hallmark of malignant transformation, we investigated the role of EGR1 in apoptosis of bone marrow cells; a cell population from which myeloid malignancies arise. We evaluated radiation induced apoptosis of Egr1+/+ and Egr1-/- bone marrow cells in vitro and in vivo. EGR1 is not required for radiation induced apoptosis of murine bone marrow cells. Neither p53 mRNA (messenger RNA) nor protein expression is regulated by EGR1 in these cells. Radiation induced apoptosis of bone marrow cells by double strand DNA breaks induced p53 activation. These results suggest EGR1 dependent signaling mechanisms do not contribute to aberrant apoptosis of malignant cells in myeloid malignancies

    The descriptive epidemiology of DSM-IV Adult ADHD in the World Health Organization World Mental Health Surveys

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    We previously reported on the cross-national epidemiology of ADHD from the first 10 countries in the WHO World Mental Health (WMH) Surveys. The current report expands those previous findings to the 20 nationally or regionally representative WMH surveys that have now collected data on adult ADHD. The Composite International Diagnostic Interview (CIDI) was administered to 26,744 respondents in these surveys in high-, upper-middle-, and low-/lower-middle-income countries (68.5% mean response rate). Current DSM-IV/CIDI adult ADHD prevalence averaged 2.8% across surveys and was higher in high (3.6%)- and upper-middle (3.0%)- than low-/lower-middle (1.4%)-income countries. Conditional prevalence of current ADHD averaged 57.0% among childhood cases and 41.1% among childhood subthreshold cases. Adult ADHD was significantly related to being male, previously married, and low education. Adult ADHD was highly comorbid with DSM-IV/CIDI anxiety, mood, behavior, and substance disorders and significantly associated with role impairments (days out of role, impaired cognition, and social interactions) when controlling for comorbidities. Treatment seeking was low in all countries and targeted largely to comorbid conditions rather than to ADHD. These results show that adult ADHD is prevalent, seriously impairing, and highly comorbid but vastly under-recognized and undertreated across countries and cultures

    Subsurface Imaging of South Brighton Spit, Christchurch, New Zealand part I: Data Collection and Processing.

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    Color poster with text and illustrations describing research conducted by Beth Ellison, W. Patrick Dryer, Jackie E. Ebert, and Todd Wermager, advised by Harry M. Jol and David Nobes.Ground penetrating radar (GPR) surveys were conducted in collaboration with the University of Canterbury in order to provide a subsurface image of coastal sedimentary deposits below the South Brighton Spit, Christchurch, New Zealand.University of Wisconsin--Eau Claire Office of Research and Sponsored Programs

    Subsurface Imaging of South Brighton Spit, Christchurch, New Zealand part II: Coastal Processes and Data Interpretation.

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    Color poster with text, illustrations, and maps describing research conducted by W. Patrick Dryer, Jackie Ebert, Beth Ellison, and Keith Erickson, advised by Harry M. Jol and David Nobes.Ground penetrating radar (GPR) surveys were collected along the width of South Brighton Spit at its most southernly extent. The processed GPR data provides a subsurface image of the coastal sedimentary deposits that can be correlated to the layering of the spit.University of Wisconsin--Eau Claire Office of Research and Sponsored Programs
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