267 research outputs found
QCD on \alpha-Clusters
It is shown that the 21264 Alpha processor can reach about 20% sustained
efficiency for the inversion of the Wilson-Dirac operator. Since fast ethernet
is not sufficient to get balancing between computation and communication on
reasonable lattice- and system-sizes, an interconnection using Myrinet is
discussed. We find a price/performance ratio comparable with state-of-the-art
SIMD-systems for lattice QCD.Comment: LATTICE99(machines), 3 page
Role of interactions in 87Rb-40K Bose-Fermi mixtures in a 3d optical lattice
We investigate the effect of interspecies interaction on a degenerate mixture
of bosonic 87Rb and fermionic 40K atoms in a three-dimensional optical lattice
potential. Using a Feshbach resonance, the 87Rb-40K interaction is tuned over a
wide range. Through an analysis of the 87Rb momentum distribution, we find a
pronounced asymmetry between strong repulsion and strong attraction. In the
latter case, the Bose-Hubbard parameters are renormalized due to self-trapping,
leading to a marked shift in the superfluid to Mott insulator transition with
increasing Bose-Fermi interaction.Comment: 5 pages, 4 figure
Relativistic Kinetic Equations for Electromagnetic, Scalar and Pseudoscalar Interactions
We derive the kinetic equations for both the covariant and equal-time Wigner
functions of Dirac particles with electromagnetic, scalar and pseudoscalar
interactions. We emphasize the constraint equations for the spinor components
in the equal-time formulation.Comment: 12 pages, no figures, revte
Free fermion antibunching in a degenerate atomic Fermi gas released from an optical lattice
Noise in a quantum system is fundamentally governed by the statistics and the
many-body state of the underlying particles. Whereas for bosonic particles the
correlated noise observed for e.g. photons or bosonic neutral atoms can still
be explained within a classical field description with fluctuating phases, the
anticorrelations in the detection of fermionic particles have no classical
analogue. The observation of such fermionic antibunching is so far scarce and
has been confined to electrons and neutrons. Here we report on the first direct
observation of antibunching of neutral fermionic atoms. Through an analysis of
the atomic shot noise in a set of standard absorption images, of a gas of
fermionic 40K atoms released from an optical lattice, we find reduced
correlations for distances related to the original spacing of the trapped
atoms. The detection of such quantum statistical correlations has allowed us to
characterise the ordering and temperature of the Fermi gas in the lattice.
Moreover, our findings are an important step towards revealing fundamental
fermionic many-body quantum phases in periodic potentials, which are at the
focus of current research.Comment: (Nature, in press
Recent results from systematic parameterizations of Ginsparg-Wilson fermions
The Fixed Point Dirac Operator and Chirally Improved Fermions both use large
numbers of gauge paths and the full Dirac structure to approximate a solution
of the Ginsparg-Wilson equation. After a brief review of the two approaches we
present recent results for quenched QCD with pion masses down to 210 MeV. We
discuss the limits and advantages of approximate parameterizations and outline
future perspectives.Comment: Lattice2002(plenary). References and Fig. 5 updated. Final version
submitted to the proceeding
Equal-Time Hierarchies in Quantum Transport Theory
We investigate in the equal-time formalism the derivation and truncation of
infinite hierarchies of equations of motion for the energy moments of the
covariant Wigner function. From these hierarchies we then extract kinetic
equations for the physical distribution functions which are related to
low-order energy moments, and show how to determine the higher order moments in
terms of these lowest order ones. We apply the general formalism to scalar and
spinor QED with classical background fields and compare with the results
derived from the three-dimensional Wigner transformation method.Comment: 44 pages, no figure
Criterion Validity and Applicability of Motor Screening Instruments in Children Aged 5-6 Years:A Systematic Review
The detection of motor developmental problems, especially developmental coordination disorder, at age 5–6 contributes to early interventions. Here, we summarize evidence on (1) criterion validity of screening instruments for motor developmental problems at age 5–6, and (2) their applicability. We systematically searched seven databases for studies assessing criterion validity of these screening instruments using the M-ABC as reference standard. We applied COSMIN criteria for systematic reviews of screening instruments to describe the correlation between the tests and the M-ABC. We extracted information on correlation coefficients or area under the receiver operating curve, sensitivity and specificity, and applicability in practice. We included eleven studies, assessing eight instruments: three performance-based tests (MAND, MOT 4–6, BFMT) and five questionnaires (DCD-Q, PQ, ASQ-3, MOQ-T-FI, M-ABC-2-C). The quality of seven studies was fair, one was good, and three were excellent. Seven studies reported low correlation coefficients or AUC (<0.70), four did not report these. Sensitivities ranged from 21–87% and specificities from 50–96%, with the MOT4–6 having the highest sensitivity and specificity. The DCD-Q, PQ, ASQ-3, MOQ-T-FI, and M-ABC-2-C scored highest on applicability. In conclusion, none of the instruments were sufficiently valid for motor screening at age 5–6. More research is needed on screening instruments of motor delay at age 5–6
Rigorous mean-field dynamics of lattice bosons: Quenches from the Mott insulator
We provide a rigorous derivation of Gutzwiller mean-field dynamics for
lattice bosons, showing that it is exact on fully connected lattices. We apply
this formalism to quenches in the interaction parameter from the Mott insulator
to the superfluid state. Although within mean-field the Mott insulator is a
steady state, we show that a dynamical critical interaction exists, such
that for final interaction parameter the Mott insulator is
exponentially unstable towards emerging long-range superfluid order, whereas
for the Mott insulating state is stable. We discuss the implications
of this prediction for finite-dimensional systems.Comment: 6 pages, 3 figures, published versio
Genes of intestinal Escherichia coli and their relation to the inflammatory activity in patients with ulcerative colitis and Crohn’s disease
Escherichia coli gene fimA was the most frequent gene that occurred in the intestine of all investigated groups. All subjects with fimA gene had significantly higher values of tumor necrosis factor alpha (TNF-α) and CRP than those with other E. coli genes. There was also a tendency to increased serum interleukin (IL)-6 levels in patients carrying the fimA gene; however, no relation was observed to serum IL-8 and IL-10. Patients with Crohn’s disease had significantly higher IL-6 than those with ulcerative colitis (UC) and controls. The highest levels of TNF-α were detected in the UC group. There were no significant differences in serum IL-8 and IL-10 between all three groups. The presence of E. coli gene fimA in the large bowel of patients with IBD is related to the immunological activity of the disease which may be important from the aspect of therapeutical strategy
Interconversion of Functional Motions between Mesophilic and Thermophilic Adenylate Kinases
Dynamic properties are functionally important in many proteins, including the enzyme adenylate kinase (AK), for which the open/closed transition limits the rate of catalytic turnover. Here, we compare our previously published coarse-grained (double-well Gō) simulation of mesophilic AK from E. coli (AKmeso) to simulations of thermophilic AK from Aquifex aeolicus (AKthermo). In AKthermo, as with AKmeso, the LID domain prefers to close before the NMP domain in the presence of ligand, but LID rigid-body flexibility in the open (O) ensemble decreases significantly. Backbone foldedness in O and/or transition state (TS) ensembles increases significantly relative to AKmeso in some interdomain backbone hinges and within LID. In contact space, the TS of AKthermo has fewer contacts at the CORE-LID interface but a stronger contact network surrounding the CORE-NMP interface than the TS of AKmeso. A “heated” simulation of AKthermo at 375K slightly increases LID rigid-body flexibility in accordance with the “corresponding states” hypothesis. Furthermore, while computational mutation of 7 prolines in AKthermo to their AKmeso counterparts produces similar small perturbations, mutation of these sites, especially positions 8 and 155, to glycine is required to achieve LID rigid-body flexibility and hinge flexibilities comparable to AKmeso. Mutating the 7 sites to proline in AKmeso reduces some hinges' flexibilities, especially hinge 2, but does not reduce LID rigid-body flexibility, suggesting that these two types of motion are decoupled in AKmeso. In conclusion, our results suggest that hinge flexibility and global functional motions alike are correlated with but not exclusively determined by the hinge residues. This mutational framework can inform the rational design of functionally important flexibility and allostery in other proteins toward engineering novel biochemical pathways
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