Persistence of low pathogenic avian influenza virus in artificial streams mimicking natural conditions of waterfowl habitats in the Mediterranean climate

Altres ajuts: acords transformatius de la UABInstituto Nacional de Investigación y Tecnologı́a Agraria y Alimentaria PID2020-114060RR-C33-INFLUOMAAvian influenza viruses (AIVs) can affect wildlife, poultry, and humans, so a One Health perspective is needed to optimize mitigation strategies. Migratory waterfowl globally spread AIVs over long distances. Therefore, the study of AIV persistence in waterfowl staging and breeding areas is key to understanding their transmission dynamics and optimizing management strategies. Here, we used artificial streams mimicking natural conditions of waterfowl habitats in the Mediterranean climate (day/night cycles of photosynthetic active radiation and temperature, low water velocity, and similar microbiome to lowland rivers and stagnant water bodies) and then manipulated temperature and sediment presence (i.e., 10-13 °C vs. 16-18 °C, and presence vs. absence of sediments). An H1N1 low pathogenic AIV (LPAIV) strain was spiked in the streams, and water and sediment samples were collected at different time points until 14 days post-spike to quantify viral RNA and detect infectious particles. Viral RNA was detected until the end of the experiment in both water and sediment samples. In water samples, we observed a significant combined effect of temperature and sediments in viral decay, with higher viral genome loads in colder streams without sediments. In sediment samples, we didn't observe any significant effect of temperature. In contrast to prior laboratory-controlled studies that detect longer persistence times, infectious H1N1 LPAIV was isolated in water samples till 2 days post-spike, and none beyond. Infectious H1N1 LPAIV wasn't isolated from any sediment sample. Our results suggest that slow flowing freshwater surface waters may provide conditions facilitating bird-to-bird transmission for a short period when water temperature are between 10 and 18 °C, though persistence for extended periods (e.g., weeks or months) may be less likely. We hypothesize that experiments simulating real environments, like the one described here, provide a more realistic approach for assessing environmental persistence of AIVs

Neutron emission in ultraperipheral Pb-Pb collisions at sNN\sqrt {s_{NN}} = 5.02 TeV

In ultraperipheral collisions (UPCs) of relativistic nuclei without overlap of nuclear densities, the two nuclei are excited by the Lorentz-contracted Coulomb fields of their collision partners. In these UPCs, the typical nuclear excitation energy is below a few tens of MeV, and a small number of nucleons are emitted in electromagnetic dissociation (EMD) of primary nuclei, in contrast to complete nuclear fragmentation in hadronic interactions. The cross sections of emission of given numbers of neutrons in UPCs of $^{208}$Pb nuclei at $\sqrt{s_{\mathrm{NN}}}=5.02$~TeV were measured with the neutron zero degree calorimeters (ZDCs) of the ALICE detector at the LHC, exploiting a similar technique to that used in previous studies performed at $\sqrt{s_{\mathrm{NN}}}=2.76$~TeV. In addition, the cross sections for the exclusive emission of 1, 2, 3, 4 and 5 forward neutrons in the EMD, not accompanied by the emission of forward protons, and thus mostly corresponding to the production of $^{207,206,205,204,203}$Pb, respectively, were measured for the first time. The predictions from the available models describe the measured cross sections well. These cross sections can be used for evaluating the impact of secondary nuclei on the LHC components, in particular, on superconducting magnets, and also provide useful input for the design of the Future Circular Collider (FCC-hh).In ultraperipheral collisions (UPCs) of relativistic nuclei without overlap of nuclear densities, the two nuclei are excited by the Lorentz-contracted Coulomb fields of their collision partners. In these UPCs, the typical nuclear excitation energy is below a few tens of MeV, and a small number of nucleons are emitted in electromagnetic dissociation (EMD) of primary nuclei, in contrast to complete nuclear fragmentation in hadronic interactions. The cross sections of emission of given numbers of neutrons in UPCs of Pb208 nuclei at sNN=5.02 TeV were measured with the neutron zero degree calorimeters (ZDCs) of the ALICE detector at the LHC, exploiting a similar technique to that used in previous studies performed at sNN=2.76 TeV. In addition, the cross sections for the exclusive emission of one, two, three, four, and five forward neutrons in the EMD, not accompanied by the emission of forward protons, and thus mostly corresponding to the production of Pb207,206,205,204,203, respectively, were measured for the first time. The predictions from the available models describe the measured cross sections well. These cross sections can be used for evaluating the impact of secondary nuclei on the LHC components, in particular, on superconducting magnets, and also provide useful input for the design of the Future Circular Collider (FCC-hh).In ultraperipheral collisions (UPCs) of relativistic nuclei without overlap of nuclear densities, the two nuclei are excited by the Lorentz-contracted Coulomb fields of their collision partners. In these UPCs, the typical nuclear excitation energy is below a few tens of MeV, and a small number of nucleons are emitted in electromagnetic dissociation (EMD) of primary nuclei, in contrast to complete nuclear fragmentation in hadronic interactions. The cross sections of emission of given numbers of neutrons in UPCs of $^{208}$Pb nuclei at $\sqrt{s_{\mathrm{NN}}}=5.02$ TeV were measured with the neutron zero degree calorimeters (ZDCs) of the ALICE detector at the LHC, exploiting a similar technique to that used in previous studies performed at $\sqrt{s_{\mathrm{NN}}}=2.76$ TeV. In addition, the cross sections for the exclusive emission of one, two, three, four, and five forward neutrons in the EMD, not accompanied by the emission of forward protons, and thus mostly corresponding to the production of $^{207,206,205,204,203}$Pb, respectively, were measured for the first time. The predictions from the available models describe the measured cross sections well. These cross sections can be used for evaluating the impact of secondary nuclei on the LHC components, in particular, on superconducting magnets, and also provide useful input for the design of the Future Circular Collider (FCC-hh)

Constraining the K‾N{\overline{\textrm{K}}}{\textrm{N}} coupled channel dynamics using femtoscopic correlations at the LHC

The interaction of ${\rm{K}^{-}}$ with protons is characterised by the presence of several coupled channels, systems like ${\rm \overline{K}^0}$n and ${\pi\Sigma}$ with a similar mass and the same quantum numbers as the ${\rm{K}^{-}}$ p state. The strengths of these couplings to the ${\rm{K}^{-}}$p system are of crucial importance for the understanding of the nature of the $\Lambda(1405)$ resonance and of the attractive ${\rm{K}^{-}}$ p strong interaction. In this article, we present measurements of the ${\rm{K}^{-}}$p correlation functions in relative momentum space obtained in pp collisions at $\sqrt{s} = 13$~TeV, in p$-$Pb collisions at $\sqrt{s_{\rm NN}} = 5.02$~TeV, and (semi)peripheral Pb$-$Pb collisions at $\sqrt{s_{\rm NN}} = 5.02$~TeV. The emitting source size, composed of a core radius anchored to the ${\rm{K}^{+}}$p correlation and of a resonance halo specific to each particle pair, varies between 1 and 2 fm in these collision systems. The strength and the effects of the ${\rm \overline{K}^0}$n and ${\pi\Sigma}$ inelastic channels on the measured ${\rm{K}^{-}}$p correlation function are investigated in the different colliding systems by comparing the data with state-of-the-art models of chiral potentials. A novel approach to determine the conversion weights $\omega$, necessary to quantify the amount of produced inelastic channels in the correlation function, is presented. In this method, particle yields are estimated from thermal model predictions, and their kinematic distribution from blast-wave fits to measured data. The comparison of chiral potentials to the measured ${\rm{K}^{-}}$p interaction indicates that, while the \mbox{${\pi\Sigma}$$-$${\rm{K}^{-}}$p} dynamics is well reproduced by the model, the coupling to the ${\rm \overline{K}^0}$n channel in the model is currently underestimated.The interaction of $\textrm{K}^{-}$with protons is characterised by the presence of several coupled channels, systems like ${\overline{\textrm{K}}}^0$n and \uppi \Sigma with a similar mass and the same quantum numbers as the $\textrm{K}^{-}$p state. The strengths of these couplings to the $\textrm{K}^{-}$p system are of crucial importance for the understanding of the nature of the $\Lambda (1405)$ resonance and of the attractive $\textrm{K}^{-}$p strong interaction. In this article, we present measurements of the $\textrm{K}^{-}$p correlation functions in relative momentum space obtained in pp collisions at $\sqrt{s}~=~13$ Te, in p–Pb collisions at $\sqrt{s_{\textrm{NN}}}~=~5.02$ Te, and (semi)peripheral Pb–Pb collisions at $\sqrt{s_{\textrm{NN}}}~=~5.02$ Te. The emitting source size, composed of a core radius anchored to the $\textrm{K}^{+}$p correlation and of a resonance halo specific to each particle pair, varies between 1 and 2 fm in these collision systems. The strength and the effects of the ${\overline{\textrm{K}}}^0$n and \uppi \Sigma inelastic channels on the measured $\textrm{K}^{-}$p correlation function are investigated in the different colliding systems by comparing the data with state-of-the-art models of chiral potentials. A novel approach to determine the conversion weights $\omega$, necessary to quantify the amount of produced inelastic channels in the correlation function, is presented. In this method, particle yields are estimated from thermal model predictions, and their kinematic distribution from blast-wave fits to measured data. The comparison of chiral potentials to the measured $\textrm{K}^{-}$p interaction indicates that, while the \uppi \Sigma –$\textrm{K}^{-}$p dynamics is well reproduced by the model, the coupling to the ${\overline{\textrm{K}}}^0$n channel in the model is currently underestimated.The interaction of $\rm{K}^{-}$ with protons is characterised by the presence of several coupled channels, systems like ${\rm \overline{K}^0}$n and $\pi\Sigma$ with a similar mass and the same quantum numbers as the $\rm{K}^{-}$p state. The strengths of these couplings to the $\rm{K}^{-}$p system are of crucial importance for the understanding of the nature of the $\Lambda(1405)$ resonance and of the attractive $\rm{K}^{-}$p strong interaction. In this article, we present measurements of the $\rm{K}^{-}$p correlation functions in relative momentum space obtained in pp collisions at $\sqrt{s}~=~13$ TeV, in p-Pb collisions at $\sqrt{s_{\mathrm{NN}}}~=~5.02$ TeV, and (semi)peripheral Pb-Pb collisions at $\sqrt{s_{\mathrm{NN}}}~=~5.02$ TeV. The emitting source size, composed of a core radius anchored to the $\rm{K}^{+}$p correlation and of a resonance halo specific to each particle pair, varies between 1 and 2 fm in these collision systems. The strength and the effects of the ${\rm \overline{K}^0}$n and $\pi\Sigma$ inelastic channels on the measured $\rm{K}^{-}$p correlation function are investigated in the different colliding systems by comparing the data with state-of-the-art models of chiral potentials. A novel approach to determine the conversion weights $\omega$, necessary to quantify the amount of produced inelastic channels in the correlation function, is presented. In this method, particle yields are estimated from thermal model predictions, and their kinematic distribution from blast-wave fits to measured data. The comparison of chiral potentials to the measured $\rm{K}^{-}$p interaction indicates that, while the $\pi\Sigma-\rm{K}^{-}$p dynamics is well reproduced by the model, the coupling to the ${\rm \overline{K}^0}$n channel in the model is currently underestimated

Enhanced deuteron coalescence probability in jets

The transverse-momentum ($p_{\rm T}$) spectra and coalescence parameters $B_2$ of (anti)deuterons are measured in pp collisions at $\sqrt{s} = 13$ TeV in and out of jets. In this measurement, the direction of the leading particle with the highest $p_{\rm T}$ in the event ($p_{\rm T}^{\rm{ lead}} > 5$ GeV/$c$) is used as an approximation for the jet axis. The event is consequently divided into three azimuthal regions and the jet signal is obtained as the difference between the Toward region, that contains jet fragmentation products in addition to the underlying event (UE), and the Transverse region, which is dominated by the UE. The coalescence parameter in the jet is found to be approximately a factor of 10 larger than that in the underlying event. This experimental observation is consistent with the coalescence picture and can be attributed to the smaller average phase-space distance between nucleons inside the jet cone as compared to the underlying event. The results presented in this Letter are compared to predictions from a simple nucleon coalescence model, where the phase space distributions of nucleons are generated using PYTHIA 8 with the Monash 2013 tuning, and to predictions from a deuteron production model based on ordinary nuclear reactions with parametrized energy-dependent cross sections tuned on data. The latter model is implemented in PYTHIA 8.3. Both models reproduce the observed large difference between in-jet and out-of-jet coalescence parametersThe transverse-momentum (pT) spectra and coalescence parameters B2 of (anti)deuterons are measured in p-p collisions at s=13  TeV for the first time in and out of jets. In this measurement, the direction of the leading particle with the highest pT in the event (pTlead>5  GeV/c) is used as an approximation for the jet axis. The event is consequently divided into three azimuthal regions, and the jet signal is obtained as the difference between the toward region, that contains jet fragmentation products in addition to the underlying event (UE), and the transverse region, which is dominated by the UE. The coalescence parameter in the jet is found to be approximately a factor of 10 larger than that in the underlying event. This experimental observation is consistent with the coalescence picture and can be attributed to the smaller average phase-space distance between nucleons in the jet cone as compared with the underlying event. The results presented in this Letter are compared to predictions from a simple nucleon coalescence model, where the phase-space distributions of nucleons are generated using pythia8 with the Monash 2013 tuning, and to predictions from a deuteron production model based on ordinary nuclear reactions with parametrized energy-dependent cross sections tuned on data. The latter model is implemented in pythia8.3. Both models reproduce the observed large difference between in-jet and out-of-jet coalescence parameters, although the almost flat trend of the B2Jet is not reproduced by the models, which instead give a decreasing trend.The transverse-momentum ($p_{\rm T}$) spectra and coalescence parameters $B_2$ of (anti)deuterons are measured in pp collisions at $\sqrt{s} = 13$ TeV for the first time in and out of jets. In this measurement, the direction of the leading particle with the highest $p_{\rm T}$ in the event ($p_{\rm T}^{\rm{ lead}} > 5$ GeV/$c$) is used as an approximation for the jet axis. The event is consequently divided into three azimuthal regions and the jet signal is obtained as the difference between the Toward region, that contains jet fragmentation products in addition to the underlying event (UE), and the Transverse region, which is dominated by the UE. The coalescence parameter in the jet is found to be approximately a factor of 10 larger than that in the underlying event. This experimental observation is consistent with the coalescence picture and can be attributed to the smaller average phase-space distance between nucleons inside the jet cone as compared to the underlying event. The results presented in this Letter are compared to predictions from a simple nucleon coalescence model, where the phase space distributions of nucleons are generated using PYTHIA 8 with the Monash 2013 tuning, and to predictions from a deuteron production model based on ordinary nuclear reactions with parametrized energy-dependent cross sections tuned on data. The latter model is implemented in PYTHIA 8.3. Both models reproduce the observed large difference between in-jet and out-of-jet coalescence parameters, although the almost flat trend of the $B^{\rm Jet}_2$ is not reproduced by the models, which instead give a decreasing trend

Prompt D0^{0}, D+^{+}, and D∗+^{*+} production in Pb–Pb collisions at sNN \sqrt{s_{\mathrm{NN}}} = 5.02 TeV

International audienceThe production of prompt D$^{0}$, D$^{+}$, and D$^{*+}$ mesons was measured at midrapidity (|y| < 0.5) in Pb–Pb collisions at the centre-of-mass energy per nucleon–nucleon pair $\sqrt{s_{\mathrm{NN}}}$ = 5.02 TeV with the ALICE detector at the LHC. The D mesons were reconstructed via their hadronic decay channels and their production yields were measured in central (0–10%) and semicentral (30–50%) collisions. The measurement was performed up to a transverse momentum (p$_{T}$) of 36 or 50 GeV/c depending on the D meson species and the centrality interval. For the first time in Pb–Pb collisions at the LHC, the yield of D$^{0}$ mesons was measured down to p$_{T}$ = 0, which allowed a model-independent determination of the p$_{T}$-integrated yield per unit of rapidity (dN/dy). A maximum suppression by a factor 5 and 2.5 was observed with the nuclear modification factor (R$_{AA}$) of prompt D mesons at p$_{T}$ = 6–8 GeV/c for the 0–10% and 30–50% centrality classes, respectively. The D-meson RAA is compared with that of charged pions, charged hadrons, and J/ψ mesons as well as with theoretical predictions. The analysis of the agreement between the measured R$_{AA}$, elliptic (v$_{2}$) and triangular (v$_{3}$) flow, and the model predictions allowed us to constrain the charm spatial diffusion coefficient D$_{s}$. Furthermore the comparison of R$_{AA}$ and v$_{2}$ with different implementations of the same models provides an important insight into the role of radiative energy loss as well as charm quark recombination in the hadronisation mechanisms.[graphic not available: see fulltext