Sensitivity of the LHC Experiments to Extra Dimensions

This conference report briefly reviews the potential of the ATLAS and CMS experiments to discover evidence of extra dimensions.Comment: Submitted for SUSY07 proceedings, 4 pages, LaTeX, 8 eps figure

A single-system account of the relationship between priming, recognition, and fluency.

A single-system computational model of priming and recognition was applied to studies that have looked at the relationship between priming, recognition, and fluency in continuous identification paradigms. The model was applied to 3 findings that have been interpreted as evidence for a multiple-systems account: (a) priming can occur for items not recognized; (b) the pattern of identification reaction times (RTs) to hits, misses, correct rejections, and false alarms can change as a function of recognition performance; and (c) fluency effects (shorter RTs to words judged old vs. judged new) and priming effects (shorter RTs to old vs. new words) can be observed in amnesic patients at levels comparable with healthy adults despite impaired or near-chance recognition. The authors' simulations suggest, contrary to previous interpretations, that these results are consistent with a single-system account

A single-system model predicts recognition memory and repetition priming in amnesia

We challenge the claim that there are distinct neural systems for explicit and implicit memory by demonstrating that a formal single-system model predicts the pattern of recognition memory (explicit) and repetition priming (implicit) in amnesia. In the current investigation, human participants with amnesia categorized pictures of objects at study and then, at test, identified fragmented versions of studied (old) and nonstudied (new) objects (providing a measure of priming), and made a recognition memory judgment (old vs new) for each object. Numerous results in the amnesic patients were predicted in advance by the single-system model, as follows: (1) deficits in recognition memory and priming were evident relative to a control group; (2) items judged as old were identified at greater levels of fragmentation than items judged new, regardless of whether the items were actually old or new; and (3) the magnitude of the priming effect (the identification advantage for old vs new items) overall was greater than that of items judged new. Model evidence measures also favored the single-system model over two formal multiple-systems models. The findings support the single-system model, which explains the pattern of recognition and priming in amnesia primarily as a reduction in the strength of a single dimension of memory strength, rather than a selective explicit memory system deficit

Intense isolectin-B4 binding in rat dorsal root ganglion neurons distinguishes c-fiber nociceptors with broad action potentials and high nav1.9 expression

Binding to isolectin-B4 (IB4) and expression of tyrosine kinase A (trkA) (the high-affinity NGF receptor) have been used to define two different subgroups of nociceptive small dorsal root ganglion (DRG) neurons. We previously showed that only nociceptors have high trkA levels. However, information about sensory and electrophysiological properties in vivo of single identified IB4-binding neurons, and about their trkA expression levels, is lacking. IB4-positive (IB4+) and small dark neurons had similar size distributions. We examined IB4-binding levels in >120 dye-injected DRG neurons with sensory and electrophysiological properties recorded in vivo. Relative immunointensities for trkA and two TTX-resistant sodium channels (Nav1.8 and Nav1.9) were also measured in these neurons. IB4+ neurons were classified as strongly or weakly IB4+. All strongly IB4+ neurons were C-nociceptor type (C-fiber nociceptive or unresponsive). Of 32 C-nociceptor-type neurons examined, ~50% were strongly IB4+, ~20% were weakly IB4+ and ~30% were IB4–. A{delta} low-threshold mechanoreceptive (LTM) neurons were weakly IB4+ or IB4–. All 33 A-fiber nociceptors and all 44 A{alpha}/beta-LTM neurons examined were IB4–. IB4+ compared with IB4– C-nociceptor-type neurons had longer somatic action potential durations and rise times, slower conduction velocities, more negative membrane potentials, and greater immunointensities for Nav1.9 but not Nav1.8. Immunointensities of IB4 binding in C-neurons were positively correlated with those of Nav1.9 but not Nav1.8. Of 23 C-neurons tested for both trkA and IB4, ~35% were trkA+/IB4+ but with negatively correlated immunointensities; 26% were IB4+/trkA–, and 35% were IB4–/trkA+. We conclude that strongly IB4+ DRG neurons are exclusively C-nociceptor type and that high Nav1.9 expression may contribute to their distinct membrane properties

TRANSFER LEARNING PERFORMANCE FOR REMOTE PASTURELAND TRAIT ESTIMATION IN REAL-TIME FARM MONITORING

In precision agriculture, having knowledge of pastureland forage biomass and moisture content prior to an ensiling process enables pastoralists to enhance silage production. While traditional trait measurement estimation methods relied on hand-crafted vegetation indices, manual measurements, or even destructive methods, remote sensing technology coupled with state-of-the-art deep learning algorithms can enable estimation using a broader spectrum of data, but generally require large volumes of labelled data, which is lacking in this domain. This work investigates the performance of a range of deep learning algorithms on a small dataset for biomass and moisture estimation that was collected with a compact remote sensing system designed to work in real time. Our results showed that applying transfer learning to Inception ResNet improved minimum mean average percentage error from 45.58% on a basic CNN, to 28.07% on biomass, and from 29.33% to 8.03% on moisture content. From scratch models and models optimised for mobile remote sensing applications (MobileNet) failed to produce the same level of improvement

Aging Predicts Decline in Explicit and Implicit Memory: A Life-Span Study

Explicit memory declines with age, but age effects on implicit memory are debated. This issue is important because if implicit memory is age invariant, it may support effective interventions in individuals experiencing memory decline. In this study, we overcame several methodological issues in past research to clarify age effects on implicit memory (priming) and their relationship to explicit memory (recognition, source memory). We (a) recruited a large life-span sample of participants (N = 1,072) during a residency at the Science Museum in London, (b) employed an implicit task that was unaffected by explicit contamination, and (c) systematically manipulated attention and depth of processing to assess their contribution to age effects. Participants witnessed a succession of overlapping colored objects, attending to one color stream and ignoring the other, and identified masked objects at test before judging whether they were previously attended, unattended, or new. Age significantly predicted decline in both explicit and implicit memory for attended items

Salish Sea Initiative Interactive Map

The Salish Sea Initiative (SSI) is a Government of Canada, Trans Mountain Expansion (TMX) Accommodation Measure designed to respond to First Nations concerns about the potential environmental impacts of human activities on coastal and marine ecosystems in the Salish Sea. Led by Fisheries and Oceans Canada, the SSI aims to support the capacity building of eligible First Nations within and around the Salish Sea to plan, develop and conduct marine stewardship activities, including environmental monitoring, traditional use studies, and cumulative effects assessments. Thirty-three First Nations are eligible to participate in SSI and the initiative runs until March 2024. A key component of the SSI is the co-development of the SSI Interactive Map (SSIM). The SSIM is a user-friendly, decision support tool that displays data layers of natural marine environmental components, stressors and Indigenous cultural components. The purpose of the map is to provide a platform for SSI participants to visualize valued components (VCs) and other information that will be useful for project planning, implementation of marine stewardship work and cumulative effects assessments. The map is associated with a data catalogue and portal and functions are being created to enable data analysis. The map also serves as a communication tool to host conversations between SSI participants and between SSI participants and the Government of Canada. Enhanced communication capabilities provide support for project planning and coordination, the creation of partnerships, as well as a shared platform for inter-generational knowledge transfer opportunities within communities. The purpose of this presentation is to outline the background and process associated with the SSIM creation and to provide a demonstration to show the work completed to date. We will also highlight future actions to be taken for map enhancement

An effect of age on implicit memory that is not due to explicit contamination: implications for single and multiple-systems theories

Recognition memory is typically weaker in healthy older relative to young adults, while performance on implicit tests (e.g., repetition priming) is often comparable between groups. Such observations are commonly taken as evidence for independent explicit and implicit memory systems. On a picture version of the continuous identification with recognition (CID-R) task, we found a reliable age-related reduction in recognition memory, while the age effect on priming did not reach statistical significance (Experiment 1). This pattern was consistent with the predictions of a formal single-system model. Experiment 2 replicated these observations using separate priming (continuous identification; CID) and recognition phases, while a combined data analysis revealed a significant effect of age on priming. In Experiment 3, we provide evidence that priming in this task is unaffected by explicit processing, and we conclude that the age difference in priming is unlikely to have been driven by differences in explicit processing between groups of young and older adults ("explicit contamination"). The results support the view that explicit and implicit expressions of memory are driven by a single underlying memory system

Sea urchin populations in the Salish Sea: recent findings regarding invertebrates that support a prized fishery and play an important role in nearshore ecosystems.

Major changes in urchin populations have been reported in recent years around the world, coupled with profound cascading effects on nearshore ecosystems. Extreme climatic events are postulated to be a common driver, along with changes in populations of predators such as sea otters and sea stars. This panel brings together ecologists from British Columbia and Washington to highlight recent results on spatial patterns and temporal trends in sea urchin populations in the Salish Sea and the exposed coast. Findings suggest differences among locations in both species abundances and ecological interactions. Topics include: abundances of individual species, locations with large aggregations, trophic interactions, potential ecosystem effects, hypothesized drivers of observed change, and effects of climate change on these dynamics. These findings touch upon two topics of key interest to communities and resource managers: sea urchin fisheries and ecosystem impacts related to over-grazing

Post-translational processing targets functionally diverse proteins in Mycoplasma hyopneumoniae

© 2016 The Authors. Mycoplasma hyopneumoniae is a genome-reduced, cell wall-less, bacterial pathogen with a predicted coding capacity of less than 700 proteins and is one of the smallest self-replicating pathogens. The cell surface of M. hyopneumoniae is extensively modified by processing events that target the P97 and P102 adhesin families. Here, we present analyses of the proteome of M. hyopneumoniae-type strain J using protein-centric approaches (one- and two-dimensional GeLC-MS/MS) that enabled us to focus on global processing events in this species. While these approaches only identified 52% of the predicted proteome (347 proteins), our analyses identified 35 surface-associated proteins with widely divergent functions that were targets of unusual endopro-teolytic processing events, including cell adhesins, lipoproteins and proteins with canonical functions in the cytosol that moonlight on the cell surface. Affinity chromatography assays that separately used heparin, fibronectin, actin and host epithelial cell surface proteins as bait recovered cleavage products derived from these processed proteins, suggesting these fragments interact directly with the bait proteins and display previously unrecognized adhesive functions. We hypothesize that protein processing is underestimated as a post-translational modification in genome-reduced bacteria and prokaryotes more broadly, and represents an important mechanism for creating cell surface protein diversity