933 research outputs found
Impact of flow on oxygen dynamics in photosynthetically active sediments
To assess the influence of boundary flow on interfacial oxygen flux in sediments inhabited by benthic phototrophs, we measured the oxygen distribution and the photosynthetic activity in an intertidal sandy core at flow velocities of 0, 2, 5, 10, and 15 cm s(-1) in a laboratory flume. The impact of flow was large; the effects were reversible and most pronounced in the velocity range of 0 to 5 cm s(-1) With increasing flow velocity, both the maximum oxygen concentration in the sediment and the oxygen penetration decreased significantly The depth of the oxygen concentration maximum was shifted over 1 mm closer towards the sediment surface at the highest flow and the diffusive boundary layer was gradually compressed to a width of 0.2 +/- 0.1 mm. The width of the photosynthetically active sediment layer decreased from 3.2 +/- 0.6 mm in stagnant water to 1.4 +/- 0.3 mm under flow, resulting in an overall reduction of gross photosynthesis. This is explained by a migration of the benthic algae (dominated by pennate diatoms) into deeper sediment layers under flow to avoid resuspension into the water, and thereby impairing photosynthesis. Despite the decrease in photosynthesis, the flux of oxygen into the water column did not change significantly, suggesting that advective processes enhanced the release of oxygen from the sediment under flow conditions. We concluded that boundary layer flow is an important factor controlling photosynthesis and oxygen release in shallow water sediments
Handwriting speed in children with Developmental Coordination Disorder: Are they really slower?
This is the post-print version of the final paper published in Research in Developmental Disabilities. The
published article is available at the link below. Changes
resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality
control mechanisms may not be reflected in this document. Changes may have been made to this work since it was
submitted for publication. Copyright @ 2013 Elsevier B.V.Handwriting difficulties are often included in descriptions of Developmental Coordination Disorder (DCD). They are cited as the most common reason for referral to health professionals following parent and teacher concerns about slow and untidy writing. The aim of this study was to compare handwriting performance in English children with and without DCD across a range of writing tasks, to gain a better understanding of the nature of ‘slowness’ so commonly reported. Twenty-eight 8–14 year-old children with a diagnosis of DCD participated in the study, with 28 typically developing age and gender matched controls. Participants completed the four handwriting tasks from the Detailed Assessment of Speed of Handwriting (DASH) and wrote their own name; all on a digitising writing tablet. The number of words written, speed of pen movements and the time spent pausing during the tasks were calculated. The findings confirmed what many professionals report, that children with DCD produce less text than their peers. However, this was not due to slow movement execution, but rather a higher percentage of time spent pausing. Discussion centres on the understanding of the pausing phenomenon in children with DCD and areas for further research.Oxford Brookes Universit
An examination of writing pauses in the handwriting of children with Developmental Coordination Disorder.
This article has been made available through the Brunel Open Access Publishing Fund.Difficulties with handwriting are reported as one of the main reasons for the referral of children with Developmental Coordination Disorder (DCD) to healthcare professionals. In a recent study we found that children with DCD produced less text than their typically developing (TD) peers and paused for 60% of a free-writing task. However, little is known about the nature of the pausing; whether they are long pauses possibly due to higher level processes of text generation or fatigue, or shorter pauses related to the movements between letters. This gap in the knowledge-base creates barriers to understanding the handwriting difficulties in children with DCD. The aim of this study was to characterise the pauses observed in the handwriting of English children with and without DCD. Twenty-eight 8-14 year-old children with a diagnosis of DCD participated in the study, with 28 TD age and gender matched controls. Participants completed the 10 min free-writing task from the Detailed Assessment of Speed of Handwriting (DASH) on a digitising writing tablet. The total overall percentage of pausing during the task was categorised into four pause time-frames, each derived from the literature on writing (250 ms to 2 s; 2-4 s; 4-10 s and >10 s). In addition, the location of the pauses was coded (within word/between word) to examine where the breakdown in the writing process occurred. The results indicated that the main group difference was driven by more pauses above 10 s in the DCD group. In addition, the DCD group paused more within words compared to TD peers, indicating a lack of automaticity in their handwriting. These findings may support the provision of additional time for children with DCD in written examinations. More importantly, they emphasise the need for intervention in children with DCD to promote the acquisition of efficient handwriting skill
Non-overlapping domain decomposition for the Richards equation via superposition operators
Simulations of saturated-unsaturated groundwater flow in heterogeneous soil can be carried out by considering non-overlapping domain decomposition problems for the Richards equation in subdomains with homogeneous soil. By the application of different Kirchhoff transformations in the different subdomains local convex minimization problems can be obtained which are coupled via superposition operators on the interface between the subdomains. The purpose of this article is to provide a rigorous mathematical foundation for this reformulation in a weak sense. In particular, this involves an analysis of the Kirchhoff transformation as a superposition operator on Sobolev and trace spaces
Magnetically Controlled Exchange Process in an Ultracold Atom-Dimer Mixture
We report on the observation of an elementary exchange process in an
optically trapped ultracold sample of atoms and Feshbach molecules. We can
magnetically control the energetic nature of the process and tune it from
endoergic to exoergic, enabling the observation of a pronounced threshold
behavior. In contrast to relaxation to more deeply bound molecular states, the
exchange process does not lead to trap loss. We find excellent agreement
between our experimental observations and calculations based on the solutions
of three-body Schr\"odinger equation in the adiabatic hyperspherical
representation. The high efficiency of the exchange process is explained by the
halo character of both the initial and final molecular states.Comment: 4 pages, 4 figure
Cultured subventricular zone progenitor cells transduced with neurogenin-2 become mature glutamatergic neurons and integrate into the dentate gyrus.
We have previously shown that transplantation of immature DCX+/NeuN+/Prox1+ neurons (found in the neonatal DG), but not undifferentiated neuronal progenitor cells (NPCs) from ventral subventricular zone (SVZ), results in neuronal maturation in vivo within the dentate niche. Here we investigated whether we could enhance the integration of SVZ NPCs by forced expression of the proneural gene Neurogenin 2 (NEUROG2). NPCs cultured from neonatal GFP-transgenic rat SVZ for 7 days in a non-differentiating medium were transduced with a retrovirus encoding NEUROG2 and DsRed or the DsRed reporter gene alone (control). By 3 days post-transduction, the NEUROG2-transduced cells maintained in culture contained mostly immature neurons (91% DCX+; 76% NeuN+), whereas the control virus-transduced cells remained largely undifferentiated (30% DCX+; <1% NeuN+). At 6 weeks following transplantation into the DG of adult male rats, there were no neurons among the transplanted cells treated with the control virus but the majority of the NEUROG2-transduced DsRed+ SVZ cells became mature neurons (92% NeuN+; DCX-negative). Although the NEUROG2-transduced SVZ cells did not express the dentate granule neuron marker Prox1, most of the NEUROG2-transduced SVZ cells (78%) expressed the glutamatergic marker Tbr1, suggesting the acquisition of a glutamatergic phenotype. Moreover, some neurons extended dendrites into the molecular layer, grew axons containing Ankyrin G+ axonal initial segments, and projected into the CA3 region, thus resembling mature DG granule neurons. A proportion of NEUROG2 transduced cells also expressed c-Fos and P-CREB, two markers of neuronal activation. We conclude that NEUROG2-transduction is sufficient to promote neuronal maturation and integration of transplanted NPCs from SVZ into the DG.This is the final version of the article. It was published by PLOS in PLOS One and can be found here: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0031547
Resonant Five-body Recombination in an Ultracold Gas of Bosonic Atoms
We combine theory and experiment to investigate five-body recombination in an
ultracold gas of atomic cesium at negative scattering length. A refined
theoretical model, in combination with extensive laboratory tunability of the
interatomic interactions, enables the five-body resonant recombination rate to
be calculated and measured. The position of the new observed recombination
feature agrees with a recent theoretical prediction and supports the prediction
of a family of universal cluster states at negative that are tied to an
Efimov trimer.Comment: 14 pages, 5 figure
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