Hyperfine magnetic field in ferromagnetic graphite

Information on atomic-scale features is required for a better understanding of the mechanisms leading to magnetism in non-metallic, carbon-based materials. This work reports a direct evaluation of the hyperfine magnetic field produced at 13C nuclei in ferromagnetic graphite by nuclear magnetic resonance (NMR). The experimental investigation was made possible by the results of first-principles calculations carried out in model systems, including graphene sheets with atomic vacancies and graphite nanoribbons with edge sites partially passivated by oxygen. A similar range of maximum hyperfine magnetic field values (18-21T) was found for all systems, setting the frequency span to be investigated in the NMR experiments; accordingly, a significant 13C NMR signal was detected close to this range without any external applied magnetic field in ferromagnetic graphite

Spontaneous CO release from Ru(II)(CO)2-protein complexes in aqueous solution, cells, and mice.

We demonstrate that Ru(II)(CO)2-protein complexes, formed by the reaction of the hydrolytic decomposition products of [fac-RuCl(κ(2)-H2NCH2CO2)(CO)3] (CORM-3) with histidine residues exposed on the surface of proteins, spontaneously release CO in aqueous solution, cells, and mice. CO release was detected by mass spectrometry (MS) and confocal microscopy using a CO-responsive turn-on fluorescent probe. These findings support our hypothesis that plasma proteins act as CO carriers after in vivo administration of CORM-3. CO released from a synthetic bovine serum albumin (BSA)-Ru(II)(CO)2 complex leads to downregulation of the cytokines interleukin (IL)-6, IL-10, and tumor necrosis factor (TNF)-α in cancer cells. Finally, administration of BSA-Ru(II)(CO)2 in mice bearing a colon carcinoma tumor results in enhanced CO accumulation at the tumor. Our data suggest the use of Ru(II)(CO)2-protein complexes as viable alternatives for the safe and spatially controlled delivery of therapeutic CO in vivo.We thank the FCT, the EU, and the EPSRC for funding. G.J.L.B. is a Royal Society University Research Fellow.This is the final published version. It first appeared at http://onlinelibrary.wiley.com/doi/10.1002/anie.201409344/abstract

Modelling inactivation of Staphylococcus spp. on sliced Brazilian dry-cured loin with thermosonication and peracetic acid combined treatment

peer-reviewedUltrasound (US) has a high capacity to increase food safety. Although high and/or moderate temperature in combination with US has been studied, the knowledge about cooling/low temperatures as well as its combined effect with chemical preservation methods is scarce. Therefore, the aim of this study was to describe the inactivation of Staphylococcus spp. (SA) present in the natural microbiota of sliced Brazilian dry-cured loin (BDL) using US (40 kHz and 5.40 W/g) at 1.6–17.9 kJ/g, temperature (T) between 6.4 and 73.6 °C and peracetic acid (PA) between 5.5 and 274.5 mg/L employing the Central Composite Rotatable Design. The model fully describes how the combination of US, T, and PA affects SA inactivation. In BDL, an increase in US acoustic energy density (kJ/g) allows the reduction of T necessary to inactivate SA because of the occurrence of synergistic effect. However, US applied at low T was inefficient. On the other hand, PA was more efficient at low T, since high T degraded this compound at different rates according to the holding T. Therefore, the data indicates a relation between the technologies used in the combined decontamination of sliced BDL improving dry-cured meat safety

Compostos bioativos, atividade antioxidante e características físicas e químicas de frutos de cagaiteira nativos do cerrado mineiro.

Dentre as várias espécies frutíferas do bioma cerrado, a cagaiteira (Eugenia dysenterica DC) vem se destacando. Seus frutos são globulosos de coloração amarelada, polpa com sabor acidificado sendo utilizado no consumo in natura ou processados. Objetivou-se caracterizar frutos por amostragem de populações de plantas existentes em três diferentes regiões de Minas Gerais: Sete Lagoas (SL), Matozinhos (MT) e Três Marias (TM). Foram coletados 90 frutos maduros em cada região sendo 30 frutos de cada árvore de forma aleatória. Os frutos foram caraterizados quanto a morfologia e avaliou-se a cor, composição centesimal, parâmetros físico-químicos e os conteúdos de frutose, glicose, carotenoides totais, compostos fenólicos totais e a capacidade antioxidante. Os frutos apresentaram formato achatado, coloração amarelo- esverdeada (parâmetros L*, a* e b*), pH entre 3,35 e 2,26, acidez titulável entre 0,42 e 0,73 g de ácido cítrico/100g de matéria fresca. Quanto a atividade antioxidante os frutos exibiram valores relevantes apenas na maior concentração do extrato metanólico (1000 µg/mL). Os frutos oriundos de algumas regiões se destacaram em parâmetros isolados: frutos de Sete Lagoas com alto teor de taninos, frutos de Matozinhos com menor valor de proteínas e frutos de Três Marias com menor conteúdo de carotenoides totais. Nenhuma das regiões estudas apresentou frutos que se sobressaíram em todos os parâmetros avaliados

Small bowel enteroscopy - A joint clinical guideline from the spanish and portuguese small bowel study groups

The present evidence-based guidelines are focused on the use of device-assisted enteroscopy in the management of small-bowel diseases. A panel of experts selected by the Spanish and Portuguese small bowel study groups reviewed the available evidence focusing on the main indications of this technique, its role in the management algorithm of each indication and on its diagnostic and therapeutic yields. A set of recommendations were issued accordingly.Estas recomendações baseadas na evidência detalham o uso da enteroscopia assistida por dispositivo no manejo clínico das doenças do intestino delgado. Um conjunto de Gastrenterologistas diferenciados em patologia do intestino delgado foi selecionado pelos grupos de estudos Espanhol e Português de intestino delgado para rever a evidência disponível sobre as principais indicações desta técnica, o seu papel nos algoritmos de manejo de cada indicação e sobre o seu rendimento diagnóstico e terapêutico. Foi gerado um conjunto de recomendações pelos autores

Cronoestratigrafía del Paleozoico Superior de América del Sur : Primera etapa de trabajo hacia una nueva propuesta

Fil: Azcuy, Carlos L.. Departamento de Geología. Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires. CABA; ArgentinaFil: Beri, Ángeles. Sección Paleontología. Departamento de Geología. Facultad de Ciencias. Montevideo; UruguayFil: Bernardes-de-Oliveira, Mary E.C.. Universidade Guarulhos. SP; BrasilFil: Carrizo, Hugo A.. Fundación Miguel Lillo. Dirección de Geología. San Miguel de Tucumán; ArgentinaFil: di Pasquo, Mercedes. Departamento de Geología. Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires. CABA; ArgentinaFil: Díaz Saravia, Pamela. Fil: González, Carlos R.. Fundación Miguel Lillo. Dirección de Geología. San Miguel de Tucumán; ArgentinaFil: Iannuzzi, Roberto. Instituto de Geociências. Universidad Federal Río Grande do Sul. Porto Alegre; BrasilFil: Lemos, Valesca B.. Instituto de Geociências. Universidad Federal Río Grande do Sul. Porto Alegre; BrasilFil: Melo, José Henrique G.. PETROBRAS/CENPES/PDEXP/BPA. Rio de Janeiro; BrasilFil: Pagani, María Alejandra. Museo Paleontológico Egidio Feruglio. Trelew. Chubut; ArgentinaFil: Rhon, Rosemarie. Departamento de Geologia Aplicada, IGCE/UNESP. Rio Claro; BrasilFil: Amenabar, Cecilia. Departamento de Geología. Facultad de Ciencias Exactas y Naturales. UBA. CABA; ArgentinaFil: Sabattini, Nora María. Facultad de Ciencias Naturales y Museo. Universidad Nacional de La Plata; ArgentinaFil: Souza, Paulo. Instituto de Geociências. Universidad Federal Río Grande do Sul. Porto Alegre; BrasilFil: Taboada, Arturo C.. Laboratorio de Investigaciones en Evolución y Biodiversidad (LIEB). Facultad de Ciencias Naturales Sede Esquel. Universidad Nacional de La Patagonia San Juan Bosco. Chubut; ArgentinaFil: Vergel, María del Milagro. Fundación Miguel Lillo. Dirección de Geología. San Miguel de Tucumán; Argentin

The inventory of geological heritage of the state of São Paulo, Brazil: Methodological basis, results and perspectives

An inventory of geological sites based on solid and clear criteria is a first step for any geoconservation strategy. This paper describes the method used in the geoheritage inventory of the State of São Paulo, Brazil, and presents its main results. This inventory developed by the geoscientific community aimed to identify geosites with scientific value in the whole state, using a systematic approach. All 142 geosites representative of 11 geological frameworks were characterised and quantitatively evaluated according to their scientific value and risk of degradation, in order to establish priorities for their future management. An online database of the inventory is under construction, which will be available to be easily consulted and updated by the geoscientific community. All data were made available to the State Geological Institute as the backbone for the implementation of a future state geoconservation strategy.The authors acknowledge the Science Without Borders Programme, Process 075/2012, which supported this study and the São Paulo Research Foundation (FAPESP), Process 2011/17261-6. We also thanks C. Mazoca for his help with maps and figures.info:eu-repo/semantics/acceptedVersio