Lagere vervanging succesformule doormelken

Doormelken blijkt onder andere in het Why dry-project een mogelijke oplossing om de koegezondheid in het begin van de lactatie te verbeteren. Maar is doormelken ook economisch interessant? Wageningen-student Johan Heeren deed een modelstudie naar de economische gevolgen van doormelken. Dit blijkt alleen interessant als het vervangingspercentage ook echt lager is

Chapter X: The Tour de France: a success story in spite of competitive imbalance and doping

International audienceThe chapter goes as follows. In the first section it is demonstrated how the Tour de France is a high quality product. This is a result from its accurate design, its management, its economic model and its finance structure, both in comparison to other mega-sporting events and with reference to tournament theory. It is not easy to assess the competitive balance in the Tour de France since, as was demonstrated in chapter 10, it is at the same time an individual and a team sport contest. After reviewing some results published in literature so far, a new metrics for evaluating competitive balanced in the Tour de France is presented in section 2. Finally, the Tour de France cannot ignore doping as a potential threat to fan attendance and TV viewing. We therefore discuss the issue of doping and a new procedure to deal with doping in section 3

Schijnwerpers op economie De M.e

Het proefbedrijf De M.e weet scherpe milieudoelstelling te realiseren. De afgelopen jaren is hierover al veel geschreven en gesproken. Regelmatig werd daarbij opgemerkt: Leuk zulke goede cijfers maar wat kost dat nou?. Dit is reden geweest voor een aantal onderzoeksinstellingen om de schijnwerpers meer te richten op de economische resultaten

Switched Spatial Impulse Response Convolution as an Ambisonic Distance-Panning Function

Ambisonics offers a robust and effective approach to the recording, processing and delivery of Spatial Audio. The Ambisonic system is often considered to provide a perceptually and computationally advantageous Spatial Audio experience in comparison to typical Binaural systems. This is true even when an end-step Binaural render is required, as is typical in Virtual or Augmented Reality systems which naturally imply audio delivery via headphones. Standard Ambisonic processing allows for the rotation of a sound field around an origin position. There is not, however, a strongly established means of modulating the radial distance of a virtual sound source from the origin. This paper presents a potential solution to an Ambisonic distance-panning function for both static and dynamic virtual sources in the form of a FOA (First Order Ambisonics) Switched-SIR (Spatial Impulse Response) Convolution Reverberator. This includes a presentation of the framework for such a function, and an analysis of audio rendered using prototype scripts

Characterisation of the Immunophenotype of Dogs with Primary Immune-Mediated Haemolytic Anaemia

Immune-mediated haemolytic anaemia (IMHA) is reported to be the most common autoimmune disease of dogs, resulting in significant morbidity and mortality in affected animals. Haemolysis is caused by the action of autoantibodies, but the immunological changes that result in their production have not been elucidated.To investigate the frequency of regulatory T cells (Tregs) and other lymphocyte subsets and to measure serum concentrations of cytokines and peripheral blood mononuclear cell expression of cytokine genes in dogs with IMHA, healthy dogs and dogs with inflammatory diseases.19 dogs with primary IMHA, 22 dogs with inflammatory diseases and 32 healthy control dogs.Residual EDTA-anti-coagulated blood samples were stained with fluorophore-conjugated monoclonal antibodies and analysed by flow cytometry to identify Tregs and other lymphocyte subsets. Total RNA was also extracted from peripheral blood mononuclear cells to investigate cytokine gene expression, and concentrations of serum cytokines (interleukins 2, 6 10, CXCL-8 and tumour necrosis factor α) were measured using enhanced chemiluminescent assays. Principal component analysis was used to investigate latent variables that might explain variability in the entire dataset.There was no difference in the frequency or absolute numbers of Tregs among groups, nor in the proportions of other lymphocyte subsets. The concentrations of pro-inflammatory cytokines were greater in dogs with IMHA compared to healthy controls, but the concentration of IL-10 and the expression of cytokine genes did not differ between groups. Principal component analysis identified four components that explained the majority of the variability in the dataset, which seemed to correspond to different aspects of the immune response.The immunophenotype of dogs with IMHA differed from that of dogs with inflammatory diseases and from healthy control dogs; some of these changes could suggest abnormalities in peripheral tolerance that permit development of autoimmune disease. The frequency of Tregs did not differ between groups, suggesting that deficiency in the number of these cells is not responsible for development of IMHA