Chance of Centralia

"F. Gano Chance, '29, president and chairman of the board of the A. B. Chance Co. of Centralia, Mo., is convinced that a well-rounded liberal education is just as important to the engineer as the necessary technical training. No matter what line of engineering a man may follow, he still must work with people, and this means not only the customer, but fellow workers and other members of society."--Page

Beyond Trial Registration: A Global Trial Bank for Clinical Trial Reporting

The prose reporting of trial information could be powerfully augmented by a computable repository of trial information-a global "trial bank.

The Dutchman Vol. 7, No. 3

● Major and Minor in Fractur ● Gilbert and Mason - Pennsylvania Wood Engravers ● Barring Out the Schoolmaster ● The Himmelreich Collection ● A Mennonite Encyclopedia ● Pennsylvania Crafts Event ● Europe Calling ● Book Note ● Pennsylvania Dutch Pioneers ● The Zehn-uhr Schtickhttps://digitalcommons.ursinus.edu/dutchmanmag/1006/thumbnail.jp

A multilevel study of leadership, empowerment, and performance in teams.

A multilevel model of leadership, empowerment, and performance was tested using a sample of 62 teams, 445 individual members, 62 team leaders, and 31 external managers from 31 stores of a Fortune 500 company. Leader-member exchange and leadership climate related differently to individual and team empowerment and interacted to influence individual empowerment. Also, several relationships were supported in more but not in less interdependent teams. Specifically, leader-member exchange related to individual performance partially through individual empowerment; leadership climate related to team performance partially through team empowerment; team empowerment moderated the relationship between individual empowerment and performance; and individual performance was positively related to team performance. Contributions to team leadership theory, research, and practices are discussed. Keywords: teams, leadership, motivation, multilevel, performance As a result of the widespread move to team-based organizations in industry, managers are often asked to lead and motivate not only individuals but also teams as a whole Perhaps owing to these same trends in industry, researchers have primarily focused their efforts at the team level of analysis without considering important individual-level processes in team contexts Accordingly, the main purpose of our study was to extend previous research and answer these theoretically and practically relevant calls for multilevel team leadership and motivation research. We do so by examining team leader behaviors and employee motivation simultaneously at both the individual and team levels of analysis. In particular, we develop and test a multilevel model of leadership and motivation through the lens of employee empowerment, a motivational concept that, over the last two de

The Pennsylvania Dutchman Vol. 8, No. 4

● Such Fancy Boxes, Yet ● Dried Corn ● Pennsylvania Dutch Cooking is Corny ● The Amish at Play ● Colonial Button Mold ● Illness and Cure of Domestic Animals Among the Pennsylvania Dutch ● Pennsylvania Dutch Pioneershttps://digitalcommons.ursinus.edu/dutchmanmag/1011/thumbnail.jp

Pennsylvania Folklife Vol. 14, No. 4

• Kutztown and America • Sixteen Years of the Folk Festival • Like the One Grandma Had! • Kutztown\u27s Mennonites • Folk Festival Program • Festival Highlights • The Ice-House in Pennsylvania • The Conestoga Wagon • Folklife Studies Bibliography 1964https://digitalcommons.ursinus.edu/pafolklifemag/1020/thumbnail.jp

A phase I trial of Flavopiridol in relapsed multiple myeloma

PURPOSE: Flavopiridol is primarily a cyclin-dependent kinase-9 inhibitor, and we performed a dose escalation trial to determine the maximum tolerated dose and safety and generate a pharmacokinetic (PK) profile. METHODS: Patients with a diagnosis of relapsed myeloma after at least two prior treatments were included. Flavopiridol was administered as a bolus and then continuous infusion weekly for 4 weeks in a 6-week cycle. RESULTS: Fifteen patients were treated at three dose levels (30 mg/m(2) bolus, 30 mg/m(2) CIV to 50 mg/m(2) bolus, and 50 mg/m(2) CIV). Cytopenias were significant, and elevated transaminases (grade 4 in 3 patients, grade 3 in 4 patients, and grade 2 in 3 patients) were noted but were transient. Diarrhea (grade 3 in 6 patients and grade 2 in 5 patients) did not lead to hospital admission. There were no confirmed partial responses although one patient with t(4;14) had a decrease in his monoclonal protein >50 % that did not persist. PK properties were similar to prior publications, and immunohistochemical staining for cyclin D1 and phospho-retinoblastoma did not predict response. CONCLUSIONS: Flavopiridol as a single agent given by bolus and then infusion caused significant diarrhea, cytopenias, and transaminase elevation but only achieved marginal responses in relapsed myelom