577 research outputs found

    Henri Temianka Correspondence; (miscellaneous)

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    This collection contains material pertaining to the life, career, and activities of Henri Temianka, violin virtuoso, conductor, music teacher, and author. Materials include correspondence, concert programs and flyers, music scores, photographs, and books.https://digitalcommons.chapman.edu/temianka_correspondence/3268/thumbnail.jp

    Henri Temianka Correspondence; (lte)

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    This collection contains material pertaining to the life, career, and activities of Henri Temianka, violin virtuoso, conductor, music teacher, and author. Materials include correspondence, concert programs and flyers, music scores, photographs, and books.https://digitalcommons.chapman.edu/temianka_correspondence/3167/thumbnail.jp

    The Clash of the Commons: An Imagined Library Commons Discourse

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    The commons has been adopted by LIS as a metaphor for transformational library spaces. However, post-colonial scholarship exposes the material violence and exclusionary practices that coincide(d) with commons-making in Europe and North America. When weighing such assessments against the traditional role of American libraries as mechanisms of colonial values, it becomes necessary for library professionals to critique their continued evocation of commons discourse from a perspective that centers decolonization. Responding to this challenge, I historicize the commons as both an imagined ideology and an actual instrument of power to contextualize Indigenous and post-colonial assessments of commons-making in the settler colonial United States and dismantle taken-for-granted definitions of the commons. I then demonstrate how the history of the US public library has served to naturalize imagined commons-making projects. Finally, I use this discussion as a lens through which to analyze the commons discourse animating a selection of promotional literature published by urban public library commons spaces. Informed by the work of Eve Tuck and K. Wayne Yang, I will argue that LIS literature’s fetishization of the commons to describe modernized urban library spaces reflects an idealized, future-oriented commons produced by the colonial consciousness that obscures the material reality of minority displacement

    Illusion and experience of speed and scale

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    Thesis (M.S.V.S.)--Massachusetts Institute of Technology, Dept. of Architecture, 1993.Includes bibliographical references (leaves 69-70).The Speed of the Earth is a proposed sculpture dealing with light as pure experience within the context of short-lived rapid movement and large scale horizontal orientation within the environment. This will be accomplished through the use of rapidly sequenced strobe lights sited in a straight east/west axis line, which create a momentary event of pure light that is both corporeal and illusive. The proposed sculpture will also addresses the concept of relative perception, the light event itself creating a tangible depiction/illustration of the speed of the Earth's rotation on its axis and representing a fixed point in space that reverses the standard point of reference for the viewer's basis of location. This thesis explores the use of linear and temporal scale in environmental art, concentrating on specific works that have direct association to aspects of the proposed thesis sculpture. The strobe light is briefly discussed. The artist's personal background and perspective are described within the context of the evolution of the thesis sculpture. The proposed thesis sculpture and its planned implementation and application is described and documented.by Mitchell Benoff.M.S.V.S

    Molecular basis of halorespiration control by CprK, a CRP-FNR type transcriptional regulator

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    Certain bacteria are able to conserve energy via the reductive dehalogenation of halo-organic compounds in a respiration-type metabolism. The transcriptional regulator CprK from Desulfitobacterium spp. induces expression of halorespiratory genes upon binding of o-chlorophenol ligands and is reversibly inactivated by oxygen through disulphide bond formation. We report crystal structures of D. hafniense CprK in the ligand-free (both oxidation states), ligand-bound (reduced) and DNA-bound states, making it the first member of the widespread CRP-FNR superfamily for which a complete structural description of both redox-dependent and allosteric molecular rearrangements is available. In conjunction with kinetic and thermodynamic ligand binding studies, we provide a model for the allosteric mechanisms underpinning transcriptional control. Amino acids that play a key role in this mechanism are not conserved in functionally distinct CRP-FNR members. This suggests that, despite significant structural homology, distinct allosteric mechanisms are used, enabling this protein family to control a very wide range of processes

    Molecular basis of halorespiration control by CprK, a CRP-FNR type transcriptional regulator

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    Certain bacteria are able to conserve energy via the reductive dehalogenation of halo-organic compounds in a respiration-type metabolism. The transcriptional regulator CprK from Desulfitobacterium spp. induces expression of halorespiratory genes upon binding of o-chlorophenol ligands and is reversibly inactivated by oxygen through disulphide bond formation. We report crystal structures of D. hafniense CprK in the ligand-free (both oxidation states), ligand-bound (reduced) and DNA-bound states, making it the first member of the widespread CRP-FNR superfamily for which a complete structural description of both redox-dependent and allosteric molecular rearrangements is available. In conjunction with kinetic and thermodynamic ligand binding studies, we provide a model for the allosteric mechanisms underpinning transcriptional control. Amino acids that play a key role in this mechanism are not conserved in functionally distinct CRP-FNR members. This suggests that, despite significant structural homology, distinct allosteric mechanisms are used, enabling this protein family to control a very wide range of processes

    Relationships between heavy metal concentrations in three different body fluids and male reproductive parameters: a pilot study

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    <p>Abstract</p> <p>Background</p> <p>Animal studies have shown the reproductive toxicity of a number of heavy metals. Very few human observational studies have analyzed the relationship between male reproductive function and heavy metal concentrations in diverse biological fluids.</p> <p>Methods</p> <p>The current study assessed the associations between seminal and hormonal parameters and the concentration of the 3 most frequent heavy metal toxicants (lead, cadmium and mercury) in three different body fluids. Sixty one men attending infertility clinics that participated in a case-control study to explore the role of environmental toxins and lifestyles on male infertility were analyzed. Concentration of lead, cadmium and mercury were measured in blood and seminal plasma and whole blood using anodic stripping voltammetry and atomic absorption spectrophotometry. Serum samples were analyzed for follicle-stimulating hormone, luteinizing hormone and testosterone. Semen analyses were performed according to World Health Organization criteria. Mann-Whitney test and Spearman's rank correlations were used for unadjusted analyses. Multiple linear regression models were performed controlling for age, body mass index and number of cigarettes per day.</p> <p>Results</p> <p>There were no significant differences between cases and controls in the concentrations of heavy metals in any of the three body fluids. In multivariate analyses using all subjects no significant associations were found between serum hormone levels and metal concentrations. However there was a significant positive association between the percentage of immotile sperms and seminal plasma levels of lead and cadmium.</p> <p>Conclusions</p> <p>Our results suggest that the presence of lead and cadmium in the reproductive tract of men may be related to a moderate alteration of their seminal parameters.</p

    Recent cadmium exposure among male partners may affect oocyte fertilization during in vitro fertilization (IVF)

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    We recently reported evidence suggesting associations between urine cadmium concentrations, reflecting long-term exposure, measured in 25 female patients (relative risk = 1.41, P = 0.412) and 15 of their male partners (relative risk = 0.19, P = 0.097) and oocyte fertilization in vitro. Blood cadmium concentrations reflect more recent exposure. We here incorporate those measures into our prior data set and employ multivariable log-binomial regression models to generate hypotheses concerning the relative effects of long-term and recent cadmium exposure on oocyte fertilization in vitro. No association is indicated for blood cadmium from women and oocyte fertilization, adjusted for urine cadmium and creatinine, blood lead and mercury, age, race/ethnicity and cigarette smoking (relative risk = 0.88, P = 0.828). However, we suggest an inverse adjusted association between blood cadmium from men and oocyte fertilization (relative risk = 0.66, P = 0.143). These results suggest that consideration of long-term and recent exposures are both important for assessing the effect of partner cadmium levels on oocyte fertilization in vitro
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