Data on alpine grassland diversity in Gran Paradiso National Park, Italy

The diversity of alpine grassland species and their functional traits constitute alpine ecosystem functioning and services that support human-wellbeing. However, alpine grassland diversity is threatened by land use and climate change. Field surveys and monitoring are necessary to understand and preserve such endangered ecosystems. Here we describe data on abundances (percentage cover) of 247 alpine plant species (including mosses and lichens) inside nine 20 m by 20 m plots that were subdivided into 2 m by 2 m subplots. The nine plots are located in Gran Paradiso National Park, Italy. They cover three distinct alpine vegetation subtypes (\u2018pure\u2019 natural grassland, sparsely vegetated \u2018rocky\u2019 grassland, and wetland) in each of three valleys (Bardoney, Colle de Nivolet and Levionaz) between 2200 and 2700 m a.s.l., i.e. above the treeline. The vegetation survey was conducted in 2015 at the peak of vegetation development during August. The dataset is provided as supplementary material and associated with the research article \u201cOptimizing sampling effort and information content of biodiversity surveys: a case study of alpine grassland\u201d [1]. See [1] for data interpretation

Young women with a disorder of sex development: learning to share information with health professionals, friends and intimate partners about bodily differences and infertility

Aim: To understand the experiences of young women with a disorder of sex development when sharing information about their body with healthcare professionals, friends and intimate partners. Background: Disorders of sex development are lifelong conditions that create bodily difference such as absence of reproductive organs which can impact on young women's fertility and sexual experiences. Design: Interpretive phenomenological analysis with thirteen young women (14-19 years old) with a disorder of sex development. Methods: The young women chose to participate in either a face-to-face semi-structured interview or to complete a paper diary between 2011-2012. Results: A superordinate theme focusing on the meaning bodily differences held for these young women is presented through three themes: self-awareness and communicating this to others; actualizing intimacy; and expressing meaning of altered fertility to self or professionals or partners. During early adolescence, the young women were guarded and reticent about sharing personal information about their disorder of sex development but as they moved towards adulthood, some of the young women learnt to engage in conversations with more confidence. Frustrations about their bodily differences and the limitations of their bodies were talked about as factors which limited physical spontaneity, impacted on their perceived sexual fulfilment and challenged the development or sustainability of close friendships or intimate partnerships. The young women wanted empathic, sensitive support from knowledgeable health professionals to help them understand their bodies. Conclusion: Attachment and a 'sense of being' were the concepts that were closely linked to the young women's development of a secure identity

Spin fluctuations in the quasi-two dimensional Heisenberg ferromagnet GdI_2 studied by Electron Spin Resonance

The spin dynamics of GdI_2 have been investigated by ESR spectroscopy. The temperature dependences of the resonance field and ESR intensity are well described by the model for the spin susceptibility proposed by Eremin et al. [Phys. Rev. B 64, 064425 (2001)]. The temperature dependence of the resonance linewidth shows a maximum similar to the electrical resistance and is discussed in terms of scattering processes between conduction electrons and localized spins.Comment: to be published in PR

Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles

Genome-wide association analyses identify 123 susceptibility loci for migraine and implicate neurovascular mechanisms in its pathophysiology. Subtype analyses highlight risk loci specific for migraine with or without aura in addition to shared risk variants.Migraine affects over a billion individuals worldwide but its genetic underpinning remains largely unknown. Here, we performed a genome-wide association study of 102,084 migraine cases and 771,257 controls and identified 123 loci, of which 86 are previously unknown. These loci provide an opportunity to evaluate shared and distinct genetic components in the two main migraine subtypes: migraine with aura and migraine without aura. Stratification of the risk loci using 29,679 cases with subtype information indicated three risk variants that seem specific for migraine with aura (in HMOX2, CACNA1A and MPPED2), two that seem specific for migraine without aura (near SPINK2 and near FECH) and nine that increase susceptibility for migraine regardless of subtype. The new risk loci include genes encoding recent migraine-specific drug targets, namely calcitonin gene-related peptide (CALCA/CALCB) and serotonin 1F receptor (HTR1F). Overall, genomic annotations among migraine-associated variants were enriched in both vascular and central nervous system tissue/cell types, supporting unequivocally that neurovascular mechanisms underlie migraine pathophysiology.Clinical epidemiolog

A framework for understanding clinical reasoning in community nursing

Background: Clinical reasoning is employed to develop solutions to health needs. The impact of the clinical environment on the organization of knowledge-guiding practice has received limited attention. This gap in the clinical landscape restricts the sharing of decision-making processes. Aims: Focusing on the community, and specifically the patient's home as a context for nursing, this paper describes the creation of a collective conceptual map for a group of community nurses. There is a twofold aim of exploring the process of exposing and articulating the clinical framework and enhancing and sharing understanding of the clinical paradigm in this context. Design: An interpretive research approach was utilized. Hermeneutic phenomenology guided the level of meaning accessed and constructivism was used to build an educational picture. Methods: Multiple methods including focus groups, observation and narrative recordings were utilized to collect and analyse research data. Results: All nurses may engage with the same concepts – health, need, care and partnerships – but organized into particular frames by the guiding practice philosophy and service organization. A four-stage framework for understanding clinical reasoning in the community setting is presented. This acknowledges the multi-faceted nature of health, the lived experience of health deficits, and is located in a participation and negotiated model of care. Practice examples are presented to expose the construction of need and response which often occurs in a triadic decision-making process. Conclusions: Environment of care has significant implications on need identification and response. Relevance to clinical practice: Mechanisms to enhance the sharing of clinical reasoning and decision-making transparency are essential to aid inter- and intra-professional communication. Presentation of a clinical reasoning framework exposes the breath of 'signals' encountered in practice and the range of knowledge employed in understanding and responding to patient need