The glacial geomorphology of the Lago Buenos Aires and Lago Pueyrredón ice lobes of central Patagonia

<p>This paper presents a glacial geomorphological map of landforms produced by the Lago General Carrera–Buenos Aires and Lago Cochrane–Pueyrredón ice lobes of the former Patagonian Ice Sheet. Over 35,000 landforms were digitized into a Geographical Information System from high-resolution (<15 m) satellite imagery, supported by field mapping. The map illustrates a rich suite of ice-marginal glacigenic, subglacial, glaciofluvial and glaciolacustrine landforms, many of which have not been mapped previously (e.g. hummocky terrain, till eskers, eskers). The map reveals two principal landform assemblages in the central Patagonian landscape: (i) an assemblage of nested latero-frontal moraine arcs, outwash plains or corridors, and inset hummocky terrain, till eskers and eskers, which formed when major ice lobes occupied positions on the Argentine steppe; and (ii) a lake-terminating system, dominated by the formation of glaciolacustrine landforms (deltas, shorelines) and localized ice-contact glaciofluvial features (e.g. outwash fans), which prevailed during deglaciation.</p

Reply to comments by Bourgois et al. (2019) on: “Glacial lake evolution and Atlantic-Pacific drainage reversals during deglaciation of the Patagonia Ice Sheet”

We welcome the comments of Bourgois et al. (2019) and the opportunity to debate geomorphology, geochronology and palaeoclimate during the Late Glacial Interglacial Transition (LGIT, ~18.0-8.0 ka) in the region of the Río Baker, central Patagonia. Bourgois et al. (2019) conclude that we have propagated inconsistencies in our proposed reconstruction of palaeolake evolution due to geomorphic analytical bias. However, in our view the empirical geomorphological data we have compiled over many field seasons has resulted in a data-rich (though still incomplete) relative chronology that enables us to evaluate inconsistencies in landscape interpretations from previously published geochronological datasets. We would argue that a geochronological bias, over any geomorphological bias, has represented the main reason for multiple landscape interpretations in this region. Indeed, the conflicting palaeolake evolution models published for the Río Baker basin (Turner et al. 2005; Bell, 2008; Hein et al., 2010; Bourgois et al., 2016; Glasser et al., 2016; Martinod et al., 2016) was a major impetus for our paper. These contrasting models were in part a result of the coincident publication of two separate geochronological datasets in 2016, one focused on optically stimulated luminescence (OSL) dating of palaeolake landforms (Glasser et al., 2016), the other cosmogenic nuclide exposure ages (Bourgois et al., 2016). Both datasets provided updates on what we termed the Turner/Hein model in Thorndycraft et al. (2019), but as they did not have access to each other’s datasets they ended up with different landscape interpretations

Reply to comments by Bourgois et al. (2019) on: “Glacial lake evolution and Atlantic-Pacific drainage reversals during deglaciation of the Patagonia Ice Sheet”

No abstract available

Transduction of SIV-Specific TCR Genes into Rhesus Macaque CD8+ T Cells Conveys the Ability to Suppress SIV Replication

The SIV/rhesus macaque model for HIV/AIDS is a powerful system for examining the contribution of T cells in the control of AIDS viruses. To better our understanding of CD8(+) T-cell control of SIV replication in CD4(+) T cells, we asked whether TCRs isolated from rhesus macaque CD8(+) T-cell clones that exhibited varying abilities to suppress SIV replication could convey their suppressive properties to CD8(+) T cells obtained from an uninfected/unvaccinated animal.We transferred SIV-specific TCR genes isolated from rhesus macaque CD8(+) T-cell clones with varying abilities to suppress SIV replication in vitro into CD8(+) T cells obtained from an uninfected animal by retroviral transduction. After sorting and expansion, transduced CD8(+) T-cell lines were obtained that specifically bound their cognate SIV tetramer. These cell lines displayed appropriate effector function and specificity, expressing intracellular IFNγ upon peptide stimulation. Importantly, the SIV suppression properties of the transduced cell lines mirrored those of the original TCR donor clones: cell lines expressing TCRs transferred from highly suppressive clones effectively reduced wild-type SIV replication, while expression of a non-suppressing TCR failed to reduce the spread of virus. However, all TCRs were able to suppress the replication of an SIV mutant that did not downregulate MHC-I, recapitulating the properties of their donor clones.Our results show that antigen-specific SIV suppression can be transferred between allogenic T cells simply by TCR gene transfer. This advance provides a platform for examining the contributions of TCRs versus the intrinsic effector characteristics of T-cell clones in virus suppression. Additionally, this approach can be applied to develop non-human primate models to evaluate adoptive T-cell transfer therapy for AIDS and other diseases

A comparison of micro-CT and thin section analysis of Lateglacial glaciolacustrine varves from Glen Roy, Scotland

Despite the prevalence of thin section analysis in studies of Quaternary sediments, there are limitations associated with the production of thin sections (sediment modification) and the inherently 2D view that a thin section affords. Non-destructive and rapid scanning technologies such as X-ray computed microtomography (μCT) enable material samples to be visualised and analysed in 3D. In a Quaternary context, however, such techniques are in their infancy. This paper assesses the optimum approach to μCT analysis of Quaternary sediments, applying the method on Lateglacial glaciolacustrine varves from Glen Roy, Scotland. Scan datasets are examined at each stage of the thin section process and comparisons are made between 2D μCT images and thin sections for the recognition of 2D sediment features, with further appraisal of 3D models to identify 3D sediment structures. Comparable sediment features are observed in 2D μCT images and thin sections, however, the μCT imaging resolution determines the precision of microfacies descriptions. Additional 3D structures are distinguished from volumetric models that are otherwise impossible to identify in thin section slides. These 3D structures can locally alter sediment properties (e.g. layer thickness) as seen in 2D thin sections and/or digital images, although such variation cannot be detected with these media. It has been demonstrated that clear benefits exist in understanding the 3D structure of Quaternary sediments, both prior to thin-sectioning to avoid complicating (e.g. deformation) structures, and after thin-sectioning to establish the complex 3D context of 2D datasets. It is recommended that μCT and thin section techniques are applied in parallel in future studies, which will profit from the integration of ‘true’ 3D data. It is also advised that samples are scanned soon after field sampling, due to the significant modification of in situ sediment structures that can occur during thin section processing

Glacial lake evolution and Atlantic-Pacific drainage reversals during deglaciation of the Patagonian Ice Sheet

Modelling experiments of drainage events from proglacial lakes of the Rio Baker catchment (central Patagonia, 46-48 degrees S) indicate that Atlantic-Pacific drainage reversals may have caused freshwater forcing of regional climate. However, much of the region remains unmapped in detail and available geochronological data is equivocal, leading to multiple published palaeolake evolution models. We evaluate these models through new geomorphological mapping from the Baker valley; cosmogenic dating of moraine boulders that demonstrates an Antarctic Cold Reversal ice readvance that blocked drainage through the Rio Baker; an altitudinal-based review of published geochronology; and regional analysis of shoreline glacio-isostasy and palaeolake levels. We use these datasets to present a new regional palaeolake evolution model underpinned by Bayesian age modelling. We demonstrate that 10(3) km(3) of freshwater was released to the Pacific over at least 6 drainage events from before 15.3-15.0 cal yr BP to the early Holocene. The final stages of lake drainage involved catastrophic flooding along the Baker valley, evidenced by high magnitude flood landforms such as boulder bars, likely caused by failure of large valley floor moraine dams. We place these drainage events in the context of Late Quaternary meltwater pathways associated with advance/retreat of the Patagonian Ice Sheet and early human occupation across the region. Although broad patterns of ice retreat and lake formation may be similar across Patagonia, driven by Southern Hemisphere palaeoclimate, regional topographic settings likely resulted in spatial and temporal heterogeneity of Atlantic-Pacific drainage reorganisation across southernmost South America. (C) 2018 The Authors. Published by Elsevier Ltd

The evolution of the Patagonian Ice Sheet from 35 ka to the present day (PATICE)

We present PATICE, a GIS database of Patagonian glacial geomorphology and recalibrated chronological data. PATICE includes 58,823 landforms and 1,669 geochronological ages, and extends from 38°S to 55°S in southern South America. We use these data to generate new empirical reconstructions of the Patagonian Ice Sheet (PIS) and subsequent ice masses and ice-dammed palaeolakes at 35 ka, 30 ka, 25 ka, 20 ka, 15 ka, 13 ka (synchronous with the Antarctic Cold Reversal), 10 ka, 5 ka, 0.2 ka and 2011 AD. At 35 ka, the PIS covered of 492.6 x103 km2, had a sea level equivalent of ~1,496 mm, was 350 km wide and 2090 km long, and was grounded on the Pacific continental shelf edge. Outlet glacier lobes remained topographically confined and the largest generated the suites of subglacial streamlined bedforms characteristic of ice streams. The PIS reached its maximum extent by 33 – 28 ka from 38°S to 48°S, and earlier, around 47 ka from 48°S southwards. Net retreat from maximum positions began by 25 ka, with ice-marginal stabilisation then at 21 – 18 ka, which was then followed by rapid irreversible deglaciation. By 15 ka, the PIS had separated into disparate ice masses, draining into large ice-dammed lakes along the eastern margin, which strongly influenced rates of recession. Glacial readvances or stabilisations occurred at least at 14 – 13 ka, 11 ka, 6 – 5 ka, 2 – 1 ka, and 0.5 – 0.2 ka. We suggest that 20th century glacial recession (% a-1) is occurring faster than at any time documented during the Holocene

Data for: The evolution of the Patagonian Ice Sheet from 35 ka to the Present Day (PATICE)

Supplementary Data. Includes Excel data tables for ages and shapefiles for ages, geomorphology and ice-sheet reconstruction

Data for: The evolution of the Patagonian Ice Sheet from 35 ka to the Present Day (PATICE)

All data used in the PATICE database is available in the Supplementary Information, which comprise: • Full Excel tables of recalibrated published ages (including all data required to rerun the calculations). • ESRI Shapefiles of each dating technique and compiled geomorphology. • ESRI Shapefiles of outlines of ice extent and uncertainty in the ice margin. • ESRI Shapefile of ice flow and ice divide at the LLGM. • ESRI Shapefile of names of outlet lobes