Identification of Linearized RMS-Voltage Dip Patterns Based on Clustering in Renewable Plants

[EN] Generation units connected to the grid are currently required to meet low-voltage ride-through (LVRT) requirements. In most developed countries, these requirements also apply to renewable sources, mainly wind power plants and photovoltaic installations connected to the grid. This study proposes an alternative characterisation solution to classify and visualise a large number of collected events in light of current limits and requirements. The authors' approach is based on linearised root-mean-square-(RMS)-voltage trajectories, taking into account LRVT requirements, and a clustering process to identify the most likely pattern trajectories. The proposed solution gives extensive information on an event's severity by providing a simple but complete visualisation of the linearised RMS-voltage patterns. In addition, these patterns are compared to current LVRT requirements to determine similarities or discrepancies. A large number of collected events can then be automatically classified and visualised for comparative purposes. Real disturbances collected from renewable sources in Spain are used to assess the proposed solution. Extensive results and discussions are also included in this study.The authors thank the financial support from the 'Ministerio de Economia y Competitividad' (Spain) and the European Union - ENE2016-78214-C2-2-R, Fulbright/Spanish Ministry of Education Visiting Scholar - PRX14/00694. This work was also supported by the US Department of Energy under contract no. DE-AC36-08-GO28308 with the National Renewable Energy LaboratoryGarcía-Sánchez, TM.; Gómez-Lázaro, E.; Muljadi, E.; Kessler, M.; Muñoz-Benavente, I.; Molina-García, A. (2018). Identification of Linearized RMS-Voltage Dip Patterns Based on Clustering in Renewable Plants. IET Generation Transmission & Distribution. 12(6):1256-1262. https://doi.org/10.1049/iet-gtd.2017.0474S12561262126Craciun B. Kerekes T. Sera D.et al.: ‘Overview of recent grid codes for PV power integration’.13th Int. Conf. on Optimization of Electrical and Electronic Equipment (OPTIM) 2012 May2012 pp.959–965‘World Energy Outlook 2012’. Technical Report International Egency Agency (IEA) 2012. Available atwww.iea.orgBehrens C.E.: ‘Energy policy: 113th congress issues’.Congressional Research Service 2013Lopes, J. A. P., Hatziargyriou, N., Mutale, J., Djapic, P., & Jenkins, N. (2007). Integrating distributed generation into electric power systems: A review of drivers, challenges and opportunities. Electric Power Systems Research, 77(9), 1189-1203. doi:10.1016/j.epsr.2006.08.016Glassmire, J., Komor, P., & Lilienthal, P. (2012). Electricity demand savings from distributed solar photovoltaics. Energy Policy, 51, 323-331. doi:10.1016/j.enpol.2012.08.022Carvalho, D., Wemans, J., Lima, J., & Malico, I. (2011). Photovoltaic energy mini-generation: Future perspectives for Portugal. Energy Policy, 39(9), 5465-5473. doi:10.1016/j.enpol.2011.05.016Battaglini, A., Komendantova, N., Brtnik, P., & Patt, A. (2012). Perception of barriers for expansion of electricity grids in the European Union. Energy Policy, 47, 254-259. doi:10.1016/j.enpol.2012.04.065‘European Commission 2010a. Energy 2020. A strategy for competitive sustainable and secure energy’. Technical Report Brussels November2011Beurskens P.V.L.W.M. Hekkenberg M.: ‘Renewable energy projections as published in the national renewable energy action plans of the european member states’. Technical Report European Environment Agency (EEA) November2011Coll-Mayor, D., Paget, M., & Lightner, E. (2007). Future intelligent power grids: Analysis of the vision in the European Union and the United States. Energy Policy, 35(4), 2453-2465. doi:10.1016/j.enpol.2006.09.001Passey, R., Spooner, T., MacGill, I., Watt, M., & Syngellakis, K. (2011). The potential impacts of grid-connected distributed generation and how to address them: A review of technical and non-technical factors. Energy Policy, 39(10), 6280-6290. doi:10.1016/j.enpol.2011.07.027Sangroniz N. Mora J.A. Teixeira M.D.: ‘Review of international grid codes for wind generation’ 2009‘Global Market Outlook for Photovoltaics Until 2016’. Technical Report European Photovoltaic Industry Association 2012. Available atwww.epia.orgKim S. Bollen M.: ‘Towards the development of a set of grid code requirements for wind farms: transient reactive power requirements’. Technical Report Available as Elforsk Report 13 : 04. Part 3 Report of Vindforsk Project V‐369 Vindforsk III January2013Tsili, M., & Papathanassiou, S. (2009). A review of grid code technical requirements for wind farms. IET Renewable Power Generation, 3(3), 308. doi:10.1049/iet-rpg.2008.0070Hossain, J., & Mahmud, A. (Eds.). (2014). Renewable Energy Integration. Green Energy and Technology. doi:10.1007/978-981-4585-27-9Sourkounis C. Tourou P.: ‘Grid code requirements for wind power integration in Europe’.Conf. Papers in Energy 2013 pp.1–9Voltage Ride-Through Capability Verification of Wind Turbines With Fully-Rated Converters Using Reachability Analysis. (2014). IEEE Transactions on Energy Conversion, 29(2), 392-405. doi:10.1109/tec.2013.2295168Mohseni, M., & Islam, S. M. (2012). Review of international grid codes for wind power integration: Diversity, technology and a case for global standard. Renewable and Sustainable Energy Reviews, 16(6), 3876-3890. doi:10.1016/j.rser.2012.03.039‘Royal Decree 1565/2010 by which regulates and modifies certain aspects of the activity of production of electric energy in special regime. (In spanish)’. Technical Report November2010Sourkounis C. Tourou P.: ‘Grid code requirements for wind power integration in Europe’.Conf. Papers in Science 2013Jiménez, F., Gómez-Lázaro, E., Fuentes, J. A., Molina-García, A., & Vigueras-Rodríguez, A. (2011). Validation of a double fed induction generator wind turbine model and wind farm verification following the Spanish grid code. Wind Energy, 15(4), 645-659. doi:10.1002/we.498Montoro D.: ‘Recommendations for unified technical regulations for grid‐connected PV systems’. Technical Report SUNRISE project – European Photovoltaic Industry Association the European Construction Industry Federation the European Association of Electrical Contractors International Union of Architects 2009. Available athttp://www.pvsunrise.eu/Merino, J., Mendoza-Araya, P., & Veganzones, C. (2014). State of the Art and Future Trends in Grid Codes Applicable to Isolated Electrical Systems. Energies, 7(12), 7936-7954. doi:10.3390/en7127936deAlmeida P. Barbosa P. Duque C.et al.: ‘Grid connection considerations for the integration of PV and wind sources’.IEEE 16th Int. Conf. on Harmonics and Quality of Power (ICHQP) May2014 pp.6–9‘Network code requirements for grid connection applicable to all generators’. Technical Report European Network of Transmission System Operators for Electricity ENTSO‐E October2013. Available athttps://www.entsoe.eu/Kagan N. Ferrari E. Matsuo N.et al.: ‘Influence of rms variation measurement protocols on electrical system performance indices for voltage sags and swells’.Proc. Ninth Int. Conf. on Harmonics and Quality of Power 2000 2000 vol.3 pp.790–795Bollen, M. H. J. (2003). Algorithms for characterizing measured three-phase unbalanced voltage dips. IEEE Transactions on Power Delivery, 18(3), 937-944. doi:10.1109/tpwrd.2003.813879Bollen M.H.: ‘Comparing voltage dip survey results’.Power Engineering Society Winter Meeting 2002 2002 vol.2 pp.1130–1134Moreno‐Muñoz A. de laRosa J.: ‘Voltage sag in highly automated factories’.Industry Applications Society Annual Meeting IAS'08 2008 pp.1–6Gomez-Lazaro, E., Fuentes, J. A., Molina-Garcia, A., & Canas-Carreton, M. (2009). Characterization and Visualization of Voltage Dips in Wind Power Installations. IEEE Transactions on Power Delivery, 24(4), 2071-2078. doi:10.1109/tpwrd.2009.2027513Gunther, E. W., & Mebta, H. (1995). A survey of distribution system power quality-preliminary results. IEEE Transactions on Power Delivery, 10(1), 322-329. doi:10.1109/61.368382Belloni F. Chiappa C. Chiumeo R.et al.: ‘Voltage dip measurements along MV lines vs primary substations measurements’.Int. Conf. on Renewable Energies and Power Quality (ICREPQ'12) March2012 pp.28–30Garcia-Sanchez, T., Gomez-Lazaro, E., Muljadi, E., Kessler, M., & Molina-Garcia, A. (2016). Statistical and Clustering Analysis for Disturbances: A Case Study of Voltage Dips in Wind Farms. IEEE Transactions on Power Delivery, 31(6), 2530-2537. doi:10.1109/tpwrd.2016.2522946Barrera Nunez V. Melendez Frigola J. Herraiz Jaramillo S.: ‘A survey on voltage sag events in power systems’.IEEE/PES Transmission and Distribution Conf. and Exposition: Latin America 2008 August2008 pp.1–3‘IEEE Standard 519‐1992: Recommended practices and requirements for harmonic control in electrical power systems’. Technical Report 1993. Available athttp://ieeexplore.ieee.org/servlet/opac?punumber=2227‘1159‐2009‐IEEE Recommended practice for monitoring electric power quality’. Technical Report June2009. Available athttp://ieeexplore.ieee.org/servlet/opac?punumber=515405

Characteristics and outcome of adult patients with acute promyelocytic leukemia and increased body mass index treated with the PETHEMA Protocols

Objective The obesity/overweight may have an influence on APL outcomes. Methods This is the biggest multicentre analysis on 1320 APL patients treated with AIDA-induction and risk-adapted consolidation between 1996 and 2012. Patients body mass index (BMI) was classified as underweight (= 30 kg/m(2)) according to the World Health Organization (WHO) criteria. Results and conclusions Relationship between male gender, older age, and other known laboratory abnormalities in overweight/obese patients was significant. The induction mortality rate was significantly higher in APL with BMI >= 25 vs BMI = 25 had a trend to lower OS (74% vs 80%; P = .06). However, in the multivariate analysis, BMI did not retain the independent predictive value (P = .46). There was no higher incidence of differentiation syndrome with BMI >= 25, but there was a trend in obese. There was no difference in relapse rate according to the BMI. In summary, overweight/obesity does not represent an independent risk factor for APL outcomes. The influence of obesity in APL patients treated with chemotherapy-free regimens remains to be established

Clinical predictors of lacunar syndrome not due to lacunar infarction

Background: Lacunar syndrome not due to lacunar infarct is poorly characterised. This single centre, retrospective study was conducted to describe the clinical characteristics of patients with lacunar syndrome not due to lacunar infarct and to identify clinical predictors of this variant of lacunar stroke. Methods: A total of 146 patients with lacunar syndrome not due to lacunar infarction were included in the "Sagrat Cor Hospital of Barcelona Stroke Registry" during a period of 19 years (1986-2004). Data from stroke patients are entered in the stroke registry following a standardized protocol with 161 items regarding demographics, risk factors, clinical features, laboratory and neuroimaging data, complications and outcome. The characteristics of these 146 patients with lacunar syndrome not due to lacunar infarct were compared with those of the 733 patients with lacunar infarction. Results: Lacunar syndrome not due to lacunar infarct accounted for 16.6% (146/879) of all cases of lacunar stroke. Subtypes of lacunar syndromes included pure motor stroke in 63 patients, sensorimotor stroke in 51, pure sensory stroke in 14, atypical lacunar syndrome in 9, ataxic hemiparesis in 5 and dysarthria-clumsy hand in 4. Valvular heart disease, atrial fibrillation, sudden onset, limb weakness and sensory symptoms were significantly more frequent among patients with lacunar syndrome not due to lacunar infarct than in those with lacunar infarction, whereas diabetes was less frequent. In the multivariate analysis, atrial fibrillation (OR = 4.62), sensorimotor stroke (OR = 4.05), limb weakness (OR = 2.09), sudden onset (OR = 2.06) and age (OR = 0.96) were independent predictors of lacunar syndrome not due to lacunar infarct. Conclusions: Although lacunar syndromes are highly suggestive of small deep cerebral infarctions, lacunar syndromes not due to lacunar infarcts are found in 16.6% of cases. The presence of sensorimotor stroke, limb weakness and sudden onset in a patient with atrial fibrillation should alert the clinician to the possibility of a lacunar syndrome not due to a lacunar infarct

Isotemporal substitution of inactive time with physical activity and time in bed: Cross-sectional associations with cardiometabolic health in the PREDIMED-Plus study

© 2019 The Author(s). Background: This study explored the association between inactive time and measures of adiposity, clinical parameters, obesity, type 2 diabetes and metabolic syndrome components. It further examined the impact of reallocating inactive time to time in bed, light physical activity (LPA) or moderate-To-vigorous physical activity (MVPA) on cardio-metabolic risk factors, including measures of adiposity and body composition, biochemical parameters and blood pressure in older adults. Methods: This is a cross-sectional analysis of baseline data from 2189 Caucasian men and women (age 55-75 years, BMI 27-40 Kg/m2) from the PREDIMED-Plus study (http://www.predimedplus.com/). All participants had ≥3 components of the metabolic syndrome. Inactive time, physical activity and time in bed were objectively determined using triaxial accelerometers GENEActiv during 7 days (ActivInsights Ltd., Kimbolton, United Kingdom). Multiple adjusted linear and logistic regression models were used. Isotemporal substitution regression modelling was performed to assess the relationship of replacing the amount of time spent in one activity for another, on each outcome, including measures of adiposity and body composition, biochemical parameters and blood pressure in older adults. Results: Inactive time was associated with indicators of obesity and the metabolic syndrome. Reallocating 30 min per day of inactive time to 30 min per day of time in bed was associated with lower BMI, waist circumference and glycated hemoglobin (HbA1c) (all p-values < 0.05). Reallocating 30 min per day of inactive time with 30 min per day of LPA or MVPA was associated with lower BMI, waist circumference, total fat, visceral adipose tissue, HbA1c, glucose, triglycerides, and higher body muscle mass and HDL cholesterol (all p-values < 0.05). Conclusions: Inactive time was associated with a poor cardio-metabolic profile. Isotemporal substitution of inactive time with MVPA and LPA or time in bed could have beneficial impact on cardio-metabolic health. Trial registration: The trial was registered at the International Standard Randomized Controlled Trial (ISRCTN: http://www.isrctn.com/ISRCTN89898870) with number 89898870 and registration date of 24 July 2014, retrospectively registered

Innovation Practices in Emerging Economies: Do University Partnerships Matter?

Enterprises’ resources and capabilities determine their ability to achieve competitive advantage. In this regard, the key innovation challenges that enterprises face are liabilities associated with their age and size, and the entry barriers imposed on them. In this line, a growing number of enterprises are starting to implement innovation practices in which they employ both internal/external flows of knowledge in order to explore/exploit innovation in collaboration with commercial or scientific agents. Within this context, universities play a significant role providing fertile knowledge-intensive environments to support the exploration and exploitation of innovative and entrepreneurial ideas, especially in emerging economies, where governments have created subsidies to promote enterprise innovation through compulsory university partnerships. Based on these ideas, the purpose of this exploratory research is to provide a better understanding about the role of universities on enterprises’ innovation practices in emerging economies. More concretely, in the context of Mexico, we explored the enterprises’ motivations to collaborate with universities in terms of innovation purposes (exploration and exploitation) or alternatives to access to public funds (compulsory requirement of being involved in a university partnership). Using a sample of 10,167 Mexican enterprises in the 2012 Research and Technological Development Survey collected by the Mexican National Institute of Statistics and Geography, we tested a multinomial regression model. Our results provide insights about the relevant role of universities inside enterprises’ exploratory innovation practices, as well as, in the access of R&D research subsidies

Lymnaea schirazensis, an Overlooked Snail Distorting Fascioliasis Data: Genotype, Phenotype, Ecology, Worldwide Spread, Susceptibility, Applicability

BACKGROUND: Lymnaeid snails transmit medical and veterinary important trematodiases, mainly fascioliasis. Vector specificity of fasciolid parasites defines disease distribution and characteristics. Different lymnaeid species appear linked to different transmission and epidemiological patterns. Pronounced susceptibility differences to absolute resistance have been described among lymnaeid populations. When assessing disease characteristics in different endemic areas, unexpected results were obtained in studies on lymnaeid susceptibility to Fasciola. We undertook studies to understand this disease transmission heterogeneity. METHODOLOGY/PRINCIPAL FINDINGS: A ten-year study in Iran, Egypt, Spain, the Dominican Republic, Mexico, Venezuela, Ecuador and Peru, demonstrated that such heterogeneity is not due to susceptibility differences, but to a hitherto overlooked cryptic species, Lymnaea schirazensis, confused with the main vector Galba truncatula and/or other Galba/Fossaria vectors. Nuclear rDNA and mtDNA sequences and phylogenetic reconstruction highlighted an old evolutionary divergence from other Galba/Fossaria species, and a low intraspecific variability suggesting a recent spread from one geographical source. Morphometry, anatomy and egg cluster analyses allowed for phenotypic differentiation. Selfing, egg laying, and habitat characteristics indicated a migration capacity by passive transport. Studies showed that it is not a vector species (n = 8572 field collected, 20 populations): snail finding and penetration by F. hepatica miracidium occur but never lead to cercarial production (n = 338 experimentally infected). CONCLUSIONS/SIGNIFICANCE: This species has been distorting fasciolid specificity/susceptibility and fascioliasis geographical distribution data. Hence, a large body of literature on G. truncatula should be revised. Its existence has henceforth to be considered in research. Genetic data on livestock, archeology and history along the 10,000-year post-domestication period explain its wide spread from the Neolithic Fertile Crescent. It is an efficient biomarker for the follow-up of livestock movements, a crucial aspect in fascioliasis emergence. It offers an outstanding laboratory model for genetic studies on susceptibility/resistance in F. hepatica/lymnaeid interaction, a field of applied research with disease control perspectives

Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study

Summary Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income countries globally, and identified factors associated with mortality. Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis, exomphalos, anorectal malformation, and Hirschsprung’s disease. Recruitment was of consecutive patients for a minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause, in-hospital mortality for all conditions combined and each condition individually, stratified by country income status. We did a complete case analysis. Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal malformation, and 517 with Hirschsprung’s disease) from 264 hospitals (89 in high-income countries, 166 in middleincome countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male. Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3). Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups). Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in lowincome countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries; p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11], p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20 [1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention (ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed (ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65 [0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality. Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between lowincome, middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger than 5 years by 2030