Expected Sensitivity to Galactic/Solar Axions and Bosonic Super-WIMPs based on the Axio-electric Effect in Liquid Xenon Dark Matter Detectors

We present systematic case studies to investigate the sensitivity of axion searches by liquid xenon detectors, using the axio-electric effect (analogue of the photoelectric effect) on xenon atoms. Liquid xenon is widely considered to be one of the best target media for detection of WIMPs (Weakly Interacting Massive Particles which may form the galactic dark matter) using nuclear recoils. Since these detectors also provide an extremely low radioactivity environment for electron recoils, very weakly-interacting low-mass particles (< 100 keV/c^2), such as the hypothetical axion, could be detected as well - in this case using the axio-electric effect. Future ton-scale liquid Xe detectors will be limited in sensitivity only by irreducible neutrino background (pp-chain solar neutrino and the double beta decay of 136Xe) in the mass range between 1 and 100 keV/c^2. Assuming one ton-year of exposure, galactic axions (as non-relativistic dark matter) could be detected if the axio-electric coupling g_Ae is greater than 10^-14 at 1 keV/c^2 (or $10^-13 at 100 keV/c^2). Below a few keV/c^2, and independent of the mass, a solar axion search would be sensitive to a coupling g_Ae ~ 10^-12. This limit will set a stringent upper bound on axion mass for the DFSV and KSVZ models for the mass ranges m_A < 0.1 eV/c^2 and < 10 eV/c^2, respectively. Vector-boson dark matter could also be detected for a coupling constant alpha'/alpha > 10^-33 (for mass 1 keV/c^2) or > 10^-27 (for mass 100 keV/c^2).Comment: 17 pages, 10 figure

Thin film evolution equations from (evaporating) dewetting liquid layers to epitaxial growth

In the present contribution we review basic mathematical results for three physical systems involving self-organising solid or liquid films at solid surfaces. The films may undergo a structuring process by dewetting, evaporation/condensation or epitaxial growth, respectively. We highlight similarities and differences of the three systems based on the observation that in certain limits all of them may be described using models of similar form, i.e., time evolution equations for the film thickness profile. Those equations represent gradient dynamics characterized by mobility functions and an underlying energy functional. Two basic steps of mathematical analysis are used to compare the different system. First, we discuss the linear stability of homogeneous steady states, i.e., flat films; and second the systematics of non-trivial steady states, i.e., drop/hole states for dewetting films and quantum dot states in epitaxial growth, respectively. Our aim is to illustrate that the underlying solution structure might be very complex as in the case of epitaxial growth but can be better understood when comparing to the much simpler results for the dewetting liquid film. We furthermore show that the numerical continuation techniques employed can shed some light on this structure in a more convenient way than time-stepping methods. Finally we discuss that the usage of the employed general formulation does not only relate seemingly not related physical systems mathematically, but does as well allow to discuss model extensions in a more unified way

Rayleigh and depinning instabilities of forced liquid ridges on heterogeneous substrates

Depinning of two-dimensional liquid ridges and three-dimensional drops on an inclined substrate is studied within the lubrication approximation. The structures are pinned to wetting heterogeneities arising from variations of the strength of the short-range polar contribution to the disjoining pressure. The case of a periodic array of hydrophobic stripes transverse to the slope is studied in detail using a combination of direct numerical simulation and branch-following techniques. Under appropriate conditions the ridges may either depin and slide downslope as the slope is increased, or first breakup into drops via a transverse instability, prior to depinning. The different transition scenarios are examined together with the stability properties of the different possible states of the system.Comment: Physics synopsis link: http://physics.aps.org/synopsis-for/10.1103/PhysRevE.83.01630

Depinning of three-dimensional drops from wettability defects

Substrate defects crucially influence the onset of sliding drop motion under lateral driving. A finite force is necessary to overcome the pinning influence even of microscale heterogeneities. The depinning dynamics of three-dimensional drops is studied for hydrophilic and hydrophobic wettability defects using a long-wave evolution equation for the film thickness profile. It is found that the nature of the depinning transition explains the experimentally observed stick-slip motion.Comment: 6 pages, 9 figures, submitted to ep

Characterization of the Hamamatsu R11410-10 3-Inch Photomultiplier Tube for Liquid Xenon Dark Matter Direct Detection Experiments

To satisfy the requirements of the next generation of dark matter detectors based on the dual phase TPC, Hamamatsu, in close collaboration with UCLA, has developed the R11410-10 photomultipler tube. In this work, we present the detailed tests performed on this device. High QE (>30%) accompanied by a low dark count rate (50 Hz at 0.3 PE) and high gain (10^7) with good single PE resolution have been observed. A comprehensive screening measurement campaign is ongoing while the manufacturer quotes a radioactivity of 20 mBq/PMT. These characteristics show the R11410-10 to be particularly suitable for the forthcoming zero background liquid xenon detectors.Comment: 19 pages, 18 figure

Avaliação do risco cardiovascular em pacientes obesos hipertensos com síndrome metabólica: estudo ARCOS

Weight loss improves metabolic abnormalities and reduces cardiovascular risk in obese hypertensive patients. To evaluate the impact of a sustained weight loss on coronary risk, 181 hypertensive patients with metabolic syndrome underwent to orlistat therapy, 120 mg, t.i.d., plus diet for 36 weeks. During therapy, Framingham risk scores (FRS) were calculated for determination of coronary heart disease risk in ten years. Body mass index decreased from 35.0 ± 4.2 to 32.6 ± 4.5 kg/m² (p 5% occurred in 64.6% of all patients, associated with improvement in glucose metabolism. Among those with abnormal glucose metabolism, 38 out 53 patients (71.7%) improved their glucose tolerance (p 5% em 64,6% de todos os pacientes, associada com melhora no metabolismo da glicose. Entre os 53 pacientes com metabolismo de glicose anormal, 38 (71,7%) melhoraram sua tolerância à glicose (p< 0,0005). Em conclusão, terapia de longa duração com orlistat auxilia a reduzir e manter mais baixo o peso corpóreo, reduzindo o risco de doença coronária e melhorando o metabolismo da glicose e protegendo, dessa maneira, contra o diabetes tipo 2.Federal University of São Paulo Divisions of EndocrinologyFederal University of São Paulo Division of NephrologyInstituto Dante Pazzaneze de Cardiologia Service of CardiologyRoche LaboratoriesUNIFESP, Divisions of EndocrinologyUNIFESP, Division of NephrologySciEL

Interpreting ambiguous ‘trace’ results in Schistosoma mansoni CCA Tests: Estimating sensitivity and specificity of ambiguous results with no gold standard

Background The development of new diagnostics is an important tool in the fight against disease. Latent Class Analysis (LCA) is used to estimate the sensitivity and specificity of tests in the absence of a gold standard. The main field diagnostic for Schistosoma mansoni infection, Kato-Katz (KK), is not very sensitive at low infection intensities. A point-of-care circulating cathodic antigen (CCA) test has been shown to be more sensitive than KK. However, CCA can return an ambiguous ‘trace’ result between ‘positive’ and ‘negative’, and much debate has focused on interpretation of traces results. Methodology/Principle findings We show how LCA can be extended to include ambiguous trace results and analyse S. mansoni studies from both Côte d’Ivoire (CdI) and Uganda. We compare the diagnostic performance of KK and CCA and the observed results by each test to the estimated infection prevalence in the population. Prevalence by KK was higher in CdI (13.4%) than in Uganda (6.1%), but prevalence by CCA was similar between countries, both when trace was assumed to be negative (CCAtn: 11.7% in CdI and 9.7% in Uganda) and positive (CCAtp: 20.1% in CdI and 22.5% in Uganda). The estimated sensitivity of CCA was more consistent between countries than the estimated sensitivity of KK, and estimated infection prevalence did not significantly differ between CdI (20.5%) and Uganda (19.1%). The prevalence by CCA with trace as positive did not differ significantly from estimates of infection prevalence in either country, whereas both KK and CCA with trace as negative significantly underestimated infection prevalence in both countries. Conclusions Incorporation of ambiguous results into an LCA enables the effect of different treatment thresholds to be directly assessed and is applicable in many fields. Our results showed that CCA with trace as positive most accurately estimated infection prevalence

Comment on "On the subtleties of searching for dark matter with liquid xenon detectors"

In a recent manuscript (arXiv:1208.5046) Peter Sorensen claims that XENON100's upper limits on spin-independent WIMP-nucleon cross sections for WIMP masses below 10 GeV "may be understated by one order of magnitude or more". Having performed a similar, though more detailed analysis prior to the submission of our new result (arXiv:1207.5988), we do not confirm these findings. We point out the rationale for not considering the described effect in our final analysis and list several potential problems with his study.Comment: 3 pages, no figure

Sanidade, transmissão via semente e patogenicidade de fungos em sementes de Cedrela fissilis procedentes da Região Sul do Brasil.

Pesquisas relacionadas à patologia de sementes de espécies florestais nativas, especialmente aquelas mais aprofundadas, são escassas. Assim, o objetivo deste estudo foi avaliar a sanidade das sementes de cedro através de dois métodos de detecção, avaliar a transmissão de fungos associados às sementes para as plântulas e avaliar a patogenicidade de fungos associados às sementes e transmitidos para as plântulas. Para tanto, sementes de seis procedências, dentre os estados do Rio Grande do Sul, Santa Catarina e Paraná, foram utilizadas. Estas foram submetidas a testes de sanidade, pelos métodos do papel-filtro e batata-dextroseágar (BDA), a teste de transmissão via sementes para as plântulas e a teste de patogenicidade de isolados de Rhizoctonia sp., patógeno escolhido por ser o mais frequente nos testes de sanidade e transmitido via semente. Os fungos encontrados em ambos os testes foram: Pestalotia sp., Rhizoctonia sp., Penicillium sp., Phomopsis sp., Rhizopus sp., Aspergillus sp. e Fusarium sp. Ambos os métodos podem ser utilizados para teste de sanidade em sementes de cedro. Os fungos transmitidos via semente para plântula foram Fusarium sp. e Rhizoctonia sp., sendo que, estes causaram danos nas raízes e posterior tombamento. Foi identificado um isolado de Rhizoctonia sp. patogênico para plântulas de cedro, causando os mesmos sintomas relatados no teste de transmissão

Dark matter search in a Beam-Dump eXperiment (BDX) at Jefferson Lab

MeV-GeV dark matter (DM) is theoretically well motivated but remarkably unexplored. This Letter of Intent presents the MeV-GeV DM discovery potential for a 1 m$^3$ segmented plastic scintillator detector placed downstream of the beam-dump at one of the high intensity JLab experimental Halls, receiving up to 10$^{22}$ electrons-on-target (EOT) in a one-year period. This experiment (Beam-Dump eXperiment or BDX) is sensitive to DM-nucleon elastic scattering at the level of a thousand counts per year, with very low threshold recoil energies ($\sim$1 MeV), and limited only by reducible cosmogenic backgrounds. Sensitivity to DM-electron elastic scattering and/or inelastic DM would be below 10 counts per year after requiring all electromagnetic showers in the detector to exceed a few-hundred MeV, which dramatically reduces or altogether eliminates all backgrounds. Detailed Monte Carlo simulations are in progress to finalize the detector design and experimental set up. An existing 0.036 m$^3$ prototype based on the same technology will be used to validate simulations with background rate estimates, driving the necessary R$\&$D towards an optimized detector. The final detector design and experimental set up will be presented in a full proposal to be submitted to the next JLab PAC. A fully realized experiment would be sensitive to large regions of DM parameter space, exceeding the discovery potential of existing and planned experiments by two orders of magnitude in the MeV-GeV DM mass range.Comment: 28 pages, 17 figures, submitted to JLab PAC 4