1,291 research outputs found
Displacement/Length Scaling Relationships for Normal Faults; a Review, Critique, and Revised Compilation
The relationship between normal fault displacement (D) and length (L) varies due to numerous factors, including fault size, maturity, basin tectonic history, and host rock lithology. Understanding how fault D and L relate is useful, given related scaling laws are often used to help refine interpretations of often incomplete, subsurface datasets, which has implications for hydrocarbon and low-carbon energy applications. Here we provide a review of D/L scaling laws for normal faults, discuss factors that could influence these relationships, including both geological factors and errors in measurement, and provide a critique of previously published D/L databases. We then present our newly assembled database of 4059 normal faults from 66 sources that include explicit information on: 1) fault length and displacement, 2) host rock lithology, 3) host basin tectonic history, and 4) maturity, as well as fault D and L through time when these data are available. We find an overall scaling law of D = 0.3L0.92, which is similar to previously published scaling equations and that varies in response to the aforementioned geological factors. Our data show that small faults (<1 m length) tend to be over-displaced compared to larger faults, active faults tend to be over-displaced compared to inactive faults, and faults with stiffer host rock lithologies, like igneous and carbonate rocks, tend to be under-displaced with respect to faults within softer, more compliant host rocks, like clastic sedimentary rocks. Our dynamic D/L through time data show that faults follow the hybrid fault growth model, i.e., they initially lengthen, during which time they will appear under-displaced, before accumulating displacement. To the best of our knowledge, this is the first comprehensive, integrated, critical study of D/L scaling laws for normal faults and the factors influencing their growth. These revised relationships can now be utilized for predicting fault length or displacement when only one variable is available and provide the basis for general understanding D/L scaling laws in the context of normal fault growth. This underpinning database is open-access and is available for analysis and manipulation by the broader structural geology community.publishedVersio
Involution of the mouse mammary gland is associated with an immune cascade and an acute-phase response, involving LBP, CD14 and STAT3
INTRODUCTION:
Involution of the mammary gland is a complex process of controlled apoptosis and tissue remodelling. The aim of the project was to identify genes that are specifically involved in this process.
METHODS:
We used Affymetrix oligonucleotide microarrays to perform a detailed transcript analysis on the mechanism of controlled involution after withdrawal of the pups at day seven of lactation. Some of the results were confirmed by semi-quantitative reverse transcriptase polymerase chain reaction, Western blotting or immunohistochemistry.
RESULTS:
We identified 145 genes that were specifically upregulated during the first 4 days of involution; of these, 49 encoded immunoglobulin genes. A further 12 genes, including those encoding the signal transducer and activator of transcription 3 (STAT3), the lipopolysaccharide receptor (CD14) and lipopolysaccharide-binding protein (LBP), were involved in the acute-phase response, demonstrating that the expression of acute-phase response genes can occur in the mammary gland itself and not only in the liver. Expression of LBP and CD14 was upregulated, at both the RNA and protein level, immediately after pup withdrawal; CD14 was strongly expressed in the luminal epithelial cells. Other genes identified suggested neutrophil activation early in involution, followed by macrophage activation late in the process. Immunohistochemistry and histological staining confirmed the infiltration of the involuting mammary tissue with neutrophils, plasma cells, macrophages and eosinophils.
CONCLUSION:
Oligonucleotide microarrays are a useful tool for identifying genes that are involved in the complex developmental process of mammary gland involution. The genes identified are consistent with an immune cascade, with an early acute-phase response that occurs in the mammary gland itself and resembles a wound healing process
Topos-Theoretic Extension of a Modal Interpretation of Quantum Mechanics
This paper deals with topos-theoretic truth-value valuations of quantum
propositions. Concretely, a mathematical framework of a specific type of modal
approach is extended to the topos theory, and further, structures of the
obtained truth-value valuations are investigated. What is taken up is the modal
approach based on a determinate lattice \Dcal(e,R), which is a sublattice of
the lattice \Lcal of all quantum propositions and is determined by a quantum
state and a preferred determinate observable . Topos-theoretic extension
is made in the functor category \Sets^{\CcalR} of which base category
\CcalR is determined by . Each true atom, which determines truth values,
true or false, of all propositions in \Dcal(e,R), generates also a
multi-valued valuation function of which domain and range are \Lcal and a
Heyting algebra given by the subobject classifier in \Sets^{\CcalR},
respectively. All true propositions in \Dcal(e,R) are assigned the top
element of the Heyting algebra by the valuation function. False propositions
including the null proposition are, however, assigned values larger than the
bottom element. This defect can be removed by use of a subobject
semi-classifier. Furthermore, in order to treat all possible determinate
observables in a unified framework, another valuations are constructed in the
functor category \Sets^{\Ccal}. Here, the base category \Ccal includes all
\CcalR's as subcategories. Although \Sets^{\Ccal} has a structure
apparently different from \Sets^{\CcalR}, a subobject semi-classifier of
\Sets^{\Ccal} gives valuations completely equivalent to those in
\Sets^{\CcalR}'s.Comment: LaTeX2
Vibrational signature of broken chemical order in a GeS2 glass: a molecular dynamics simulation
Using density functional molecular dynamics simulations, we analyze the
broken chemical order in a GeS glass and its impact on the dynamical
properties of the glass through the in-depth study of the vibrational
eigenvectors. We find homopolar bonds and the frequencies of the corresponding
modes are in agreement with experimental data. Localized S-S modes and 3-fold
coordinated sulfur atoms are found to be at the origin of specific Raman peaks
whose origin was not previously clear. Through the ring size statistics we
find, during the glass formation, a conversion of 3-membered rings into larger
units but also into 2-membered rings whose vibrational signature is in
agreement with experiments.Comment: 11 pages, 8 figures; to appear in Phys. Rev.
Environment and Rural Affairs Monitoring & Modelling Programme – ERAMMP Report-26: ‘Quick Start’ Agricultural Small Sectors Modelling.
The potential impact of Brexit on the farming sector and wider environment is just one of the many challenges facing the Welsh Government. There are a range of decision and modelling tools which can be used to explore potential outcomes and the areas at risk where the environmental regulatory floor needs to be enhanced or social transition programmes put in place.
To meet this challenge in Wales, a partnership between the Welsh Government, their stakeholders and a consortium of research organisations led by the UK Centre for Ecology and Hydrology (UKCEH) was formed. This partnership, called ERAMMP, (https://erammp.wales/en) combined expert knowledge and a range of decision and modelling tools to examine potential changes in agricultural land use that might result from Brexit, and to explore potential benefits of new land management options
Cancellation of Global Anomalies in Spontaneously Broken Gauge Theories
We discuss the generalization to global gauge anomalies of the familiar
procedure for the cancellation of local gauge anomalies in effective theories
of spontaneously broken symmetries. We illustrate this mechanism in a recently
proposed six-dimensional extension of the standard model.Comment: 5 pages; v2: version to appear in Phys. Rev.
Tidal inlet function: field evidence and numerical simulation in the INDIA project
In recognition of the environmentally sensitive nature of inlets and of a requirement to improve present knowledge of their function, the INDIA project has studied a small natural tidal inlet located in the Ría Formosa, Algarve, Portugal. The project has used state-of-the-art field equipment to study present day processes, and a range of numerical models to extend the spatial and temporal range of the measurements. Underpinned by knowledge of inlet evolution over several years, and by knowledge of other inlet systems, a conceptual model describing the medium-to long-term evolution of the inlet is presented. Key elements of the model are then examined with reference to field observations and to numerical simulations of tides, waves, sediments and morphology. Supported by historical evidence of inlet evolution in the Ría Formosa, the picture that emerges of inlet dynamics is essentially one of relative simplicity and predictability in the short-to medium-term
Pseudospin symmetry as a relativistic dynamical symmetry in the nucleus
Pseudospin symmetry in nuclei is investigated by solving the Dirac equation
with Woods-Saxon scalar and vector radial potentials, and studying the
correlation of the energy splittings of pseudospin partners with the nuclear
potential parameters. The pseudospin interaction is related to a
pseudospin-orbit term that arises in a Schroedinger-like equation for the lower
component of the Dirac spinor. We show that the contribution from this term to
the energy splittings of pseudospin partners is large. The near pseudospin
degeneracy results from a significant cancelation among the different terms in
that equation, manifesting the dynamical character of this symmetry in the
nucleus. We analyze the isospin dependence of the pseudospin symmetry and find
that its dynamical character is behind the different pseudospin splittings
observed in neutron and proton spectra of nuclei.Comment: 13 pages, 9 figures, uses REVTeX4 macro
- …