7,529 research outputs found
Interplay of spin density wave and superconductivity with different pairing symmetry
A model study for the coexistence of the spin density wave and
superconductivity is presented. With reference to the recent angle resolved
photo emmission experimental data in high T_c cuprates, presence of the nested
pieces of bands is assumed. The single band Hubbard model, therefore, when
treated within the Hatree-Fock mean field theory leads to a spin density wave
(SDW) ground state. The superconductivity (SC) is assumed to be due to a
generalised attractive potential with a separable form without specifying to
any particular origin. It therefore allows a comparative study of the
coexistence of superconductivity of different order parameter symmetry with the
spin density wave state. We find that the phase diagram, comprising of the
amplitudes of the respective gaps (SC and SDW) Vs. band filling resembles to
that of the high T_c cuprates only when the order parameter of the
superconducting phase has d-wave symmetry. Thermal variation of different order
parameters (e.g, SC and SDW) also show interesting coexistence and reentrance
behaviors that are consistent with experimental observations, specially for the
borocarbides.Comment: 8 pages, 6 figures (postscript attached), Physica C (in press
Synthesis, Analgesic, Anti-inflammatory and Antimicrobial Activities of Some Novel Pyrazoline Derivatives
Purpose: Microbial infections often produce pain and inflammation. Chemotherapeutic, analgesic and anti-inflammatory drugs are prescribed simultaneously in normal practice. The compound possessing all three activities is not common.The purpose of the present study was to examine whether molecular modification might result in detection of new potential antirheumatic drugs having antimicrobial activities.
Method: A series of novel 4-(5′-substituted aryl-4′, 5′-dihydropyrazole-3′-yl-amino) phenols 2a-f have been synthesized by treating substituted aryl-N-chalconyl amino phenols 1a-f with hydrazine hydrate. The starting materials were synthesized from p-aminoacetophenone. Their structures were confirmed by IR, 1H NMR spectral data. The synthesized compounds were investigated for analgesic, ant-inflammatory and antimicrobial activities.
Result: The data reported in Tables 2, 3 & 4 shows that effect of variation in chemical structure on activity was rather unpredictable. Seldom did a particular structural modification lead to uniform alteration in activity in all tests. The substitution which appeared to be most important for high order of activity in the greatest number of test was the p-choloroaryl group. The introduction of p-nitro and p-hydroxy group in aryl moiety of the pyrazole analogs 2c and 2e produce compounds with potent analgesic, anti-inflamatory and, in a few cases, antimicrobial properties.
Conclusion: The observed increase in analgesic, anti-inflammatory and antimicrobial activities are attributed to the presence of 4-NO2, 2-OH and 4-Cl in phenyl ring at 5-position of pyrazoline ring of synthesized compounds. In some cases their activities are equal or more potent than the standard drugs.
Keywords: Pyrazole, Analgesic, Anti-inflammatory, Antibacterial activity Tropical Journal of Pharmaceutical Research Vol. 7 (2) 2008: pp. 961-96
A phenomenological equation of state for isospin asymmetric nuclear matter
A phenomenological momentum-independent (MID) model is constructed to
describe the equation of state (EOS) for isospin asymmetric nuclear matter,
especially the density dependence of the nuclear symmetry energy
. This model can reasonably describe the general
properties of the EOS for symmetric nuclear matter and the symmetry energy
predicted by both the sophisticated isospin and momentum dependent MDI model
and the Skyrme-Hartree-Fock approach. We find that there exists a nicely linear
correlation between and as well as between and , where and represent, respectively, the
slope and curvature parameters of the symmetry energy at the normal nuclear
density while and are, respectively, the
incompressibility and the third-order derivative parameter of symmetric nuclear
matter at . These correlations together with the empirical
constraints on , and lead to an
estimation of -477 MeV MeV for the
second-order isospin asymmetry expansion coefficient for the incompressibility
of asymmetric nuclear matter at the saturation point.Comment: 9 pages, 4 figures, contribution to Special Topic on Large-Scale
Scientific Facilities (LSSF) in Science in China Series G: Physics, Mechanics
& Astronom
Ferritins: furnishing proteins with iron
Ferritins are a superfamily of iron oxidation, storage and mineralization proteins found throughout the animal, plant, and microbial kingdoms. The majority of ferritins consist of 24 subunits that individually fold into 4-α-helix bundles and assemble in a highly symmetric manner to form an approximately spherical protein coat around a central cavity into which an iron-containing mineral can be formed. Channels through the coat at inter-subunit contact points facilitate passage of iron ions to and from the central cavity, and intrasubunit catalytic sites, called ferroxidase centers, drive Fe2+ oxidation and O2 reduction. Though the different members of the superfamily share a common structure, there is often little amino acid sequence identity between them. Even where there is a high degree of sequence identity between two ferritins there can be major differences in how the proteins handle iron. In this review we describe some of the important structural features of ferritins and their mineralized iron cores and examine in detail how three selected ferritins oxidise Fe2+ in order to explore the mechanistic variations that exist amongst ferritins. We suggest that the mechanistic differences reflect differing evolutionary pressures on amino acid sequences, and that these differing pressures are a consequence of different primary functions for different ferritins
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Measurement of Î (1520) production in pp collisions at âs=7TeV and pâPb collisions at âsNN=5.02TeV
The production of the Î (1520) baryonic resonance has been measured at midrapidity in inelastic pp collisions at s=7TeV and in pâPb collisions at sNN=5.02TeV for non-single diffractive events and in multiplicity classes. The resonance is reconstructed through its hadronic decay channel Î (1520) â pK - and the charge conjugate with the ALICE detector. The integrated yields and mean transverse momenta are calculated from the measured transverse momentum distributions in pp and pâPb collisions. The mean transverse momenta follow mass ordering as previously observed for other hyperons in the same collision systems. A Blast-Wave function constrained by other light hadrons (Ï, K, KS0, p, Î) describes the shape of the Î (1520) transverse momentum distribution up to 3.5GeV/c in pâPb collisions. In the framework of this model, this observation suggests that the Î (1520) resonance participates in the same collective radial flow as other light hadrons. The ratio of the yield of Î (1520) to the yield of the ground state particle Î remains constant as a function of charged-particle multiplicity, suggesting that there is no net effect of the hadronic phase in pâPb collisions on the Î (1520) yield
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Measurement of prompt D0, D+, D*+, and DS+ production in pâPb collisions at âsNN = 5.02 TeV
The measurement of the production of prompt D0, D+, D*+, and DS+ mesons in protonâlead (pâPb) collisions at the centre-of-mass energy per nucleon pair of sNN = 5.02 TeV, with an integrated luminosity of 292 ± 11 ÎŒbâ1, are reported. Differential production cross sections are measured at mid-rapidity (â0.96 < ycms< 0.04) as a function of transverse momentum (pT) in the intervals 0 < pT< 36 GeV/c for D0, 1 < pT< 36 GeV/c for D+ and D*+, and 2 < pT< 24 GeV/c for D+ mesons. For each species, the nuclear modification factor RpPb is calculated as a function of pT using a proton-proton (pp) ref- erence measured at the same collision energy. The results are compatible with unity in the whole pT range. The average of the non-strange D mesons RpPb is compared with theoretical model predictions that include initial-state effects and parton transport model predictions. The pT dependence of the D0, D+, and D*+ nuclear modification factors is also reported in the interval 1 < pT< 36 GeV/c as a function of the collision centrality, and the central-to-peripheral ratios are computed from the D-meson yields measured in different centrality classes. The results are further compared with charged-particle measurements and a similar trend is observed in all the centrality classes. The ratios of the pT-differential cross sections of D0, D+, D*+, and DS+ mesons are also reported. The DS+ and D+ yields are compared as a function of the charged-particle multiplicity for several pT intervals. No modification in the relative abundances of the four species is observed with respect to pp collisions within the statistical and systematic uncertainties. [Figure not available: see fulltext.]
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Measurement of Ï(1S) Elliptic Flow at Forward Rapidity in Pb-Pb Collisions at sqrt[s_{NN}]=5.02ââTeV.
The first measurement of the Ï(1S) elliptic flow coefficient (v_{2}) is performed at forward rapidity (2.
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