Education through cinema. Franklin Delano Roosevelt's polio on the movies (III): Hyde Park on Hudson (2012)

Through the figure of Franklin D. Roosevelt in 1939, permanent sequelae of spinal poliomyelitis are analyzed. The limitations caused by the disease and the way of minimising their impact are discussed. Sexuality in physical disabilities is studied.Se analizan las secuelas permanentes de la polio espinal a través de la figura de Franklin D. Roosevelt (FDR) en 1939. Se comentan las limitaciones que ocasionan y las formas de minimizarlas. Se hace un estudio de la sexualidad en la discapacidad física

Education through cinema. Franklin Delano Roosevelt's polio on the movies (I): Sunrise at Campobello (1960)

This paper, in accordance with educational purposes, analyzes acute paralytic poliomyelitis, its evolution and the rehabilitation of its sequels. All these aspects of the disease are reflected in the film Sunrise at Campobello, through the figure of Franklin Delano Roosevelt and his life between 1921 and 1928. Clinical, psychological, epidemiological, rehabilitative, family and social aspects of polio infection are examined.</p

Education through cinema. Franklin Delano Roosevelt's polio on the movies (III): Hyde Park on Hudson (2012)

Through the figure of Franklin D. Roosevelt in 1939, permanent sequelae of spinal poliomyelitis are analyzed. The limitations caused by the disease and the way of minimising their impact are discussed. Sexuality in physical disabilities is studied.</p

Education through cinema. Franklin Delano Roosevelt's polio on the movies (I): Warm Springs (2005)

This paper, in accordance with educational purposes, analyzes acute paralytic poliomyelitis, its evolution and the rehabilitation of its sequels. All these aspects of the disease are reflected in the film Warm Springs, through the figure of Franklin Delano Roosevelt and his life between 1921 and 1928. Clinical, psychological, epidemiological, rehabilitative, family and social aspects of polio infection are examined./n Se analiza con fines docentes la polio aguda paralítica, su evolución y la rehabilitación de las secuelas permanentes a través de la figura de Franklin Delano Roosevelt entre 1921 y 1928, utilizando la película Warm Springs. Se examinan aspectos clínicos, psicológicos, epidemiológicos, rehabilitadores, familiares y sociales

Evidencia de asociación entre el gen SLC6A4 y efectos epistáticos con variantes en HTR2A en la etiología del autismo en la población antioqueña

Introduction. Autism spectrum disorders are severe neurodevelopmental disorders with a stronggenetic component. The potential role of the serotoninergic system in the development of autistic disorder has been based on the observation of hyperserotoninemia in autistic subjects and the results of drug treatment studies. Multiple molecules involved in serotonin metabolism and neurotransmission have been studied; however, replication studies have been inconsistent. This may be partially related to the marked genetic heterogeneity of autism in different populations.Objectives. The relationship between autism and single nucleotide polymorphisms of SLC6A4, HTR2Aand ITGB3 genes was evaluated in an urban population of northwestern Colombia.Materials and methods. In Antioquia, Colombia, 42 families with history of autism were screened for 10 SNPs in SLC6A4, HTR2A and ITGB3 genes and evaluated for associations with the transmission disequilibrium test. The interactions among these genes and autism was assessed with multidimensional reduction methods.Results. A significant main effect was seen among the SLC6A4 gene variants rs4583306 (OR=2.6,p=0.004) and rs2066713 (OR=2.2, p=0.03). No main effect of the ITGB3 or HTR2A variants was found, however, in the interaction effects, the SLC6A4 and HTR2A genes demonstrated significant evidence of association with autism (p&lt;0.001).Conclusion. Significant association of markers were discovered within the SLC6A4 gene and the combination of SLC6A4 and HTR2A (S-A) genes to autism. These results were consistent with previous studies conducted in other populations and provide further evidence for the implication of these rotoninergic system in the etiology of autistic disorders. doi: http://dx.doi.org/10.7705/biomedica.v32i4.593Introducción. El espectro autista constituye un grupo de trastornos graves del neurodesarrollo, conun fuerte componente genético. Se ha sugerido un papel importante del sistema serotoninérgico en el desarrollo de este grupo de trastornos, con base en los estudios de respuesta a medicamentos y la hiperserotoninemia, característica común en el autismo. Se han implicado múltiples moléculas en el metabolismo y la neurotransmisión de la serotonina; sin embargo, los resultados de los estudios hantenido poca congruencia entre diferentes poblaciones.Objetivos. Evaluar la relación entre el autismo y el polimorfismo de nucleótido simple (SingleNucleotide Polymorphism, SNP) en los genes SLC6A4, HTR2A e ITGB3, en una muestra de la población antioqueña.Materiales y métodos. Se genotipificaron 42 núcleos familiares con autismo para 10 variantes enlos genes SLC6A4, ITGB3 y HTR2A. Se evaluó la asociación utilizando la prueba de desequilibrio enla transmisión. Se exploró el impacto de la interacción entre estos genes y el autismo, utilizando la reducción multidimensional.Resultados. Se encontró asociación de las variantes rs4583306 (OR=2,6, p=0,004) y rs2066713(OR=2,2 p=0,03), en el gen SLC6A4, y asociación de combinaciones genotípicas entre los genes SLC6A4 y HTR2A y el riesgo de autismo (p=0,0001).Conclusiones. Se encontró asociación significativa con variantes en el gen transportador de serotoninacon el autismo, al igual que interacción entre variantes en los genes HTR2A con SLC6A4. Estos resultados concuerdan con los de estudios previos en otras poblaciones y son pruebas a favor delpapel del sistema serotoninérgico en la etiología del espectro autista. doi: http://dx.doi.org/10.7705/biomedica.v32i4.59

Education through cinema. Franklin Delano Roosevelt's polio on the movies (I): Warm Springs (2005)

This paper, in accordance with educational purposes, analyzes acute paralytic poliomyelitis, its evolution and the rehabilitation of its sequels. All these aspects of the disease are reflected in the film Warm Springs, through the figure of Franklin Delano Roosevelt and his life between 1921 and 1928. Clinical, psychological, epidemiological, rehabilitative, family and social aspects of polio infection are examined. </p

Educación inclusiva con calidad : construyendo capacidad institucional para la atención a la diversidad : guía

Resumen basado en el de la publicaciónRuta metodológica de apoyo a las instituciones educativas para que realicen de manera sistemática, su proceso de transformación de la gestión hacia el enfoque de inclusión. Esto contribuye a desarrollar la capacidad institucional para que se brinde atención educativa pertinente a la diversidad de la población y a la que se encuentra en situación de vulnerabilidad; a través de la consolidación de modelos educativos caracterizados por ser pluralistas, abiertos, flexibles y equitativos.ES