Developments in electromagnetic tomography instrumentation.

A new EMT sensor and instrumentation is described which combines the best features of previous systems and has a modular structure to allow for future system expansion and development

Application of nonextensive statistics to particle and nuclear physics

We present an overview of possible imprints of non-extensitivity in particle and nucler physics. Special emphasis is put on the intrinsic fluctuations present in the system under consideration as the possible source of nonextensivity. The possible connection of nonextensivity and the self organized criticality apparently being observed in some cosmic rays and hadronic experiments will also be discussed.Comment: Contribution to International School and Conference on "Non Extensive Thermodynamics and physical applications", Villasimius-Capo Boi (Cagliari), Italy, 23-30 March 200

Game saturation of intersecting families

We consider the following combinatorial game: two players, Fast and Slow, claim $k$-element subsets of $[n]=\{1,2,...,n\}$ alternately, one at each turn, such that both players are allowed to pick sets that intersect all previously claimed subsets. The game ends when there does not exist any unclaimed $k$-subset that meets all already claimed sets. The score of the game is the number of sets claimed by the two players, the aim of Fast is to keep the score as low as possible, while the aim of Slow is to postpone the game's end as long as possible. The game saturation number is the score of the game when both players play according to an optimal strategy. To be precise we have to distinguish two cases depending on which player takes the first move. Let $gsat_F(\mathbb{I}_{n,k})$ and $gsat_S(\mathbb{I}_{n,k})$ denote the score of the saturation game when both players play according to an optimal strategy and the game starts with Fast's or Slow's move, respectively. We prove that $\Omega_k(n^{k/3-5}) \le gsat_F(\mathbb{I}_{n,k}),gsat_S(\mathbb{I}_{n,k}) \le O_k(n^{k-\sqrt{k}/2})$ holds

Malaria parasite translocon structure and mechanism of effector export.

The putative Plasmodium translocon of exported proteins (PTEX) is essential for transport of malarial effector proteins across a parasite-encasing vacuolar membrane into host erythrocytes, but the mechanism of this process remains unknown. Here we show that PTEX is a bona fide translocon by determining structures of the PTEX core complex at near-atomic resolution using cryo-electron microscopy. We isolated the endogenous PTEX core complex containing EXP2, PTEX150 and HSP101 from Plasmodium falciparum in the 'engaged' and 'resetting' states of endogenous cargo translocation using epitope tags inserted using the CRISPR-Cas9 system. In the structures, EXP2 and PTEX150 interdigitate to form a static, funnel-shaped pseudo-seven-fold-symmetric protein-conducting channel spanning the vacuolar membrane. The spiral-shaped AAA+ HSP101 hexamer is tethered above this funnel, and undergoes pronounced compaction that allows three of six tyrosine-bearing pore loops lining the HSP101 channel to dissociate from the cargo, resetting the translocon for the next threading cycle. Our work reveals the mechanism of P. falciparum effector export, and will inform structure-based design of drugs targeting this unique translocon

Visions in monochrome: Families, marriage and the individualisation thesis

This paper takes issue with the way in which the individualisation thesis – in which it is assumed that close relationships have become tenuous and fragile - has become so dominant in ‘new’ sociological theorising about family life. Although others have criticised this thesis, in this paper the main criticism derives from empirical research findings carried out with members of transnational families living in Britain whose values and practices do not fit easily with ideas of individualisation. It is argued that we need a much more complex and less linear notion of how families change across generations and in time

Third World gap year projects: Youth transitions and the mediation of risk

This is the post-print version of the final published article. The definitive, peer-reviewed and edited version of this article is available from the link below. Copyright @ 2008 Pion.In recent years in the UK there has been a great expansion in the number of young people travelling to Third World countries between school and university in order to participate as volunteers on structured gap year projects. Travel to such places is commonly perceived as ‘risky’, and takes young people outside the protective cocoon of UK health and safety legislation. One of the functions played by the providers of gap year projects is to mediate risk. On the basis of analysis of promotional literature, interviews with organisers of gap year projects, and focus groups of returned volunteers, in this paper I argue that the various strategies of risk mediation undertaken by gap year providers serve to reconcile modernising tendencies in UK society toward risk control and structure with postmodern inclinations towards individualisation and uncertainty

When the working day is through: The end of work as identity?

This article seeks to present a counter-case to the ‘end of work thesis’ advocated by writers such as Beck, Sennett and Bauman. It argues that work remains a significant locus of personal identity and that the depiction by these writers of endemic insecurity in the workplace is inaccurate and lacks empirical basis. The article draws upon case study data to illustrate how, across a range of workplaces, work remains an importance source of identity, meaning and social affiliation