Associations between university students’ online learning preferences, readiness, and satisfaction

The aim of this study was to examine the associations between the preferences, readiness, and satisfaction of freshman learners after taking online courses. The study group was comprised of Turkish students (892 females, 396 males) who attended their first-year classes at a public university. Participating students attended courses in different departments, but all took these courses for one year online. Data were analysed using optimal scaling analysis. Nonlinear canonical correlation analysis (OVERALS) was used as the variables examined were of different scale levels. According to our findings, learners who preferred face-to-face format were individuals with low levels of learner control, motivation, and satisfaction, and individuals who preferred the online format had high satisfaction levels. Individuals who preferred to take courses in a blended format had low or medium levels of self-directed learning, no previous online course experience, and a medium level of control

A postpartum woman diagnosed with multiple vertebral fragility fractures due to pregnancy and lactation-associated osteoporosis

Pregnancy and lactation-associated osteoporosis (PLO) is a rare condition diagnosed with vertebral fractures detected in late pregnancy and early postpartum periods. The incidence of PLO is reported to be 0.4 in 100 000 women. Maternal bone resorption and absorption of calcium from the intestines are increased in order to ensure adequate calcium transfer to the fetus, 80% of which is in the last trimester. Bone mineral density decreases during lactation and is associated with high bone turnover. Although various factors have been suggested to be responsible, the cause and etiopathogenesis of osteoporosis associated with pregnancy and lactation have not been fully elucidated. Herein, we reported a 28 year-old primigravid woman without risk factors for secondary osteoporosis diagnosed with vertebral fractures at postpartum third month

Alfa-tokoferol’ün ağır sepsiste sitokin düzeyleri ve gastrik intramukozal ph üzerine etkisi

Amaç: Ağır sepsis gelişen olgularda alfa-tokoferol’ün sitokin düzeylerine ve gastrik intramukozal pH üzerine etkisi araştırıldı. Hastalar ve Yöntemler: Çalışmada ağır sepisli 40 hasta rastgele iki gruba ayrıldı. Grup I’deki (n=20) olgulara üç gün 600 mg alfa tokoferol intramusküler, grup II’deki (n=20) olgulara aynı volümde serum fizyolojik uygulandı. Her iki grupta hemodinamik parametreler, glutatyon, katalaz düzeyleri, nazofarengeal vücut ısısı, arteryel kan gazı değişiklikleri, plazma sitokin düzeyleri (interlökin 1? ve 6), biyokimyasal parametreler ve intramukozal pH, yoğun bakım ünitesinde ve mekanik ventilatöre bağlı kalış süresi ve mortalite oranı kaydedildi. Bütün ölçümler başlangıç (çalışmaya başlamadan 15 dakika önce) ve alfa-tokoferol verildikten 24, 48, 72 ve 96 saat sonra yapıldı. Bulgular: İki grup arasında ölçülen parametrelerin hiçbirinde anlamlı fark saptanmadı (p>0.05). Sonuç: Ağır sepsisli olgularda üç gün süreyle verilen 600 mg alfa-tokoferol’ün hemodinamik ve biyokimyasal parametreler, gastrik intramukozal pH veya sitokin düzeylerine veya hasta prognozu üzerine herhangi bir etkisini saptamadık.Objectives: We evaluated the effects of alpha-tocopherol on serum cytokine levels and gastric intramucosal pH in patients with severe sepsis. Patients ve Methods: Forty patients with severe sepsis were randomized to two groups. Group I (n=20) received 600 mg alpha-tocopherol intramuscularly, and group II (control group, n=20) received the same dose physiological saline solution for three days. The following data were recorded for both groups: hemodynamic parameters, glutathione, catalase levels, nasopharyngeal body temperature, arterial blood gas changes, plasma cytokine levels (interleukin 1≤ and 6), biochemical parameters and intramucosal pH, length of stay in the intensive care unit, duration of mechanical ventilation support, and mortality. All measurements were made at baseline (15 min before alpha-tocopherol administration) and 24, 48, 72, and 96 hours after alpha-tocopherol administration. Results: None of the parameters evaluated differed significantly between the two groups (p>0.05). Conclusion: We found that intramuscular alpha-tocopherol 600 mg did not affect hemodynamic and biochemical parameters, gastric intramucosal pH, cytokine levels, or prognosis in patients with severe sepsis

Yüksek pozitif ekspiryum sonu basıncı nedeniyle oluşan pnömomediyastinum olgusu

A 26-year-old female patient, who presented to the emergency department with chronic renal failure, general condition disturbance and dyspnea, was intubated due to low oxygen saturation. The results of the blood biochemical test were normal except for low saturation. Our case did not have any coronary artery disease or obstructive pulmonary disease. While she was undergoing the positive end-expiratory pressure (PEEP) treatment in the intensive care unit, the patient was detected to have right heart failure on her echocardiogram examination and pneumomediastinum was found on her direct radiography examination and on chest x-ray and computed tomography (CT) on the 2nd day of her hospitalization. The development of pneumomediastinum associated with PEEP for low saturation appears to be a rare phenomenon. In accompany with the findings of the case, the examination data and the literature information were prepared as a case report.Kronik böbrek yetmezliği, genel durum bozukluğu ve solunum sıkıntısı ile acil servise başvuran 26 yaşındaki kadın hasta satürasyon problemi nedeniyle entübe edildi. Satürasyon düşüklüğü dışında genel kan biyokimyasında belirgin patoloji ayırt edilmedi. Olguda koroner arter hastalığı ya da kronik obstruktif akciğer hastalığı yoktu. Yoğun bakımda, pozitif ekspiryum sonu basınç (PEEP) tedavisi altındayken, ekokardiyografi (EKO) tetkikinde olgunun sağ kalp yetmezliği olduğu ve direkt grafi tetkikinde, yatışının 2. gününde akciğer grafisinde ve bilgisayarlı tomografi (BT) tetkikinde pnömomediyastinum tespit edildi. Düşük saturasyon için yapılan pozitif expirium sonu basınç (PEEP) tedavisi altında iken pnömomediastinum gelişmesi nadir bir durumdur. Olgunun bulguları eşliğinde tetkik verileri ve literatür bilgisi olgu sunumu olarak hazırlandı

Yüksek pozitif ekspiryum sonu basıncı nedeniyle oluşan pnömomediyastinum olgusu

A 26-year-old female patient, who presented to the emergency department with chronic renal failure, general condition disturbance and dyspnea, was intubated due to low oxygen saturation. The results of the blood biochemical test were normal except for low saturation. Our case did not have any coronary artery disease or obstructive pulmonary disease. While she was undergoing the positive end-expiratory pressure (PEEP) treatment in the intensive care unit, the patient was detected to have right heart failure on her echocardiogram examination and pneumomediastinum was found on her direct radiography examination and on chest x-ray and computed tomography (CT) on the 2nd day of her hospitalization. The development of pneumomediastinum associated with PEEP for low saturation appears to be a rare phenomenon. In accompany with the findings of the case, the examination data and the literature information were prepared as a case report.Kronik böbrek yetmezliği, genel durum bozukluğu ve solunum sıkıntısı ile acil servise başvuran 26 yaşındaki kadın hasta satürasyon problemi nedeniyle entübe edildi. Satürasyon düşüklüğü dışında genel kan biyokimyasında belirgin patoloji ayırt edilmedi. Olguda koroner arter hastalığı ya da kronik obstruktif akciğer hastalığı yoktu. Yoğun bakımda, pozitif ekspiryum sonu basınç (PEEP) tedavisi altındayken, ekokardiyografi (EKO) tetkikinde olgunun sağ kalp yetmezliği olduğu ve direkt grafi tetkikinde, yatışının 2. gününde akciğer grafisinde ve bilgisayarlı tomografi (BT) tetkikinde pnömomediyastinum tespit edildi. Düşük saturasyon için yapılan pozitif expirium sonu basınç (PEEP) tedavisi altında iken pnömomediastinum gelişmesi nadir bir durumdur. Olgunun bulguları eşliğinde tetkik verileri ve literatür bilgisi olgu sunumu olarak hazırlandı

Why do some patients with stage 1A and 1B endometrial endometrioid carcinoma experience recurrence? A retrospective study in search of prognostic factors

Objectives: Endometrial endometrioid carcinoma (EEC) is the most encountered subtype of endometrial cancer (EC). Our study aimed to investigate the factors affecting recurrence in patients with stage 1A and 1B EEC. Material and methods: Our study included 284 patients diagnosed with the International Federation of Gynecology and Obstetrics stage 1A/1B EEC in our center from 2010 to 2018. The clinicopathological characteristics of the patients were obtained retrospectively from their electronic files. Results: The median age of the patients was 60 years (range 31–89). The median follow-up time of the patients was 63.6 months (range 3.3–185.6). Twenty-two (7.74%) patients relapsed during follow-up. Among the relapsed patients, 59.1% were at stage 1A ECC, and 40.9% were at stage 1B. In our study, the one-, three-, and five-year recurrence-free survival (RFS) rates were 98.9%, 95.4%, and 92.9%, respectively. In the multivariate analysis, grade and tumor size were found to be independent parameters of RFS in all stage 1 EEC patients. Furthermore, the Ki-67 index was found to affect RFS in stage 1A EEC patients, and tumor grade affected RFS in stage 1B EEC patients. In the time-dependent receiver operating characteristic curve analysis, the statistically significant cut-off values were determined for tumor size and Ki-67 index in stage 1 EEC patients. Conclusions: Stage 1-EEC patients in the higher risk group in terms of tumor size, Ki-67, and grade should be closely monitored for recurrence. Defining the prognostic factors for recurrence in stage 1 EEC patients may lead to changes in follow-up algorithms

Outcomes of high-risk breast lesions diagnosed using image-guided core needle biopsy: results from a multicenter retrospective study

PURPOSEThe clinical management of high-risk lesions using image-guided biopsy is challenging. This study aimed to evaluate the rates at which such lesions were upgraded to malignancy and identify possible predictive factors for upgrading high-risk lesions.METHODSThis retrospective multicenter analysis included 1.343 patients diagnosed with high-risk lesions using an image-guided core needle or vacuum-assisted biopsy (VAB). Only patients managed using an excisional biopsy or with at least one year of documented radiological follow-up were included. For each, the Breast Imaging Reporting and Data System (BI-RADS) category, number of samples, needle thickness, and lesion size were correlated with malignancy upgrade rates in different histologic subtypes. Pearson’s chi-squared test, the Fisher–Freeman–Halton test, and Fisher’s exact test were used for the statistical analyses.RESULTSThe overall upgrade rate was 20.6%, with the highest rates in the subtypes of intraductal papilloma (IP) with atypia (44.7%; 55/123), followed by atypical ductal hyperplasia (ADH) (38.4%; 144/375), lobular neoplasia (LN) (12.7%; 7/55), papilloma without atypia (9.4%; 58/611), flat epithelial atypia (FEA) (8.7%; 10/114), and radial scars (RSs) (4.6%; 3/65). There was a significant relationship between the upgrade rate and BI-RADS category, number of samples, and lesion size Lesion size was the most predictive factor for an upgrade in all subtypes.CONCLUSIONADH and atypical IP showed considerable upgrade rates to malignancy, requiring surgical excision. The LN, IP without atypia, pure FEA, and RS subtypes showed lower malignancy rates when the BI-RADS category was lower and in smaller lesions that had been adequately sampled using VAB. After being discussed in a multidisciplinary meeting, these cases could be managed with follow-up instead of excision

Web Tabanlı Öz-Değerlendirme Sisteminde Algılanan Öz Müdahalenin Etkililiği

In this study Web Based Self-Assessment System (WB-SS) was developed by upgrading an online test tool. The developed system provides learners to test themselves and receive delayed feedback . This study was conducted at Hacettepe University, Computer Education and Instructional Technology Department with 59 pre-service teachers who were enrolled in the Educational Measurement and Evaluation course. According to the research results, the effect of cognition regulation awareness on the effectiveness of perceived self-intervention was found significant, however the effect of cognition knowledge wasn t significant. Cognition regulation explained 20% of the variance of the effectiveness of perceived self-intervention. Only the effect of task value (sub-dimension of motivation) on the effectiveness of self-intervention was positively. There is no considerable difference between achievement increments according to number of test taken.Bu araştırmada, belirlenen bir sistemde güncellemeler yapılarak öğrenenlerin kendilerini test edebilecekleri ve ertelenmiş dönüt alabilecekleri Web Tabanlı Öz-Değerlendirme Sistemi ortaya konulmuştur. Araştırmanın çalışma grubunu Hacettepe Üniversitesi Eğitim Fakültesi Bilgisayar ve Öğretim Teknolojileri Eğitimi Bölümünde okuyan ve Eğitimde Ölçme ve Değerlendirme dersini alanlar oluşturmaktadır. Araştırma sonuçlarına göre öğrenenlerin Bilişin Düzenlemesi farkındalığının WT-ÖS'de algılanan öz müdahale etkililiği üzerine anlamlı bir etkisi varken, Biliş Bilgisi farkındalığının anlamlı etkisinin olmadığı görülmüştür. Bununla beraber öğrenenlerin Bilişin Düzenlenmesi puanları WT-ÖS'deki algılanan öz müdahalenin etkililiğinin %20'sini açıklamaktadır. Güdülenme stratejilerinden sadece görev değerinin pozitif yönde etkisi olduğu görülmüştür. Öğrenenlerin test sayısına göre başarı gelişiminde istatistiksel olarak anlamlı bir farklılık olmadığı sonucuna ulaşılmıştır